Sakai Hiromi

J-GLOBAL         Last updated: Sep 17, 2019 at 19:20
 
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Name
Sakai Hiromi
E-mail
hirosakainaramed-u.ac.jp
URL
http://www.naramed-u.ac.jp/~chem/
Affiliation
Nara Medical University
Section
Faculty of Liberal Arts and Sciences / School of Medicine, Department of Chemistry
Job title
Professor
Degree
PhD(D.Eng)(Waseda University), PhD(D.Med.Sci.)(Keio University)
Research funding number
70318830
ORCID ID
0000-0002-0681-3032

Research Areas

 
 

Academic & Professional Experience

 
Apr 2013
 - 
Mar 2014
客員上級研究員(研究院客員教授), 重点領域研究機構, 早稲田大学
 
Apr 2013
   
 
Professor, Department of Chemistry, Nara Medical University
 
Apr 2012
 - 
Mar 2013
Senior Researcher (Professor), Organization for University Research Initiatives, Waseda University
 
Sep 2009
 - 
Mar 2013
Principal Investigator, Waseada Bioscience Research Institute in Singapore
 
Oct 2011
 - 
Mar 2012
Principal researcher (Associate Professor), Organization for University Research Initiatives, Waseda University
 
Apr 2002
 - 
Mar 2012
Visiting lecturer, Visiting Associate Professor, Center for Integrated Medical Research, Keio University
 
Apr 2007
 - 
Mar 2010
Associate Professor, Research Institute for Science and Engineering, Waseda University
 
Oct 2003
 - 
Mar 2007
Associate Professor, Advanced Research Institute for Science and Engineering, Waseda University
 
Apr 1999
 - 
Sep 2003
Lecturer, Advanced Research Institute for Science and Engineering, Waseda University
 
Apr 1994
 - 
Mar 1999
Researcher, Advanced Research Institute for Science and Engineering, Waseda University
 
Jun 1996
 - 
Apr 1998
海外特別研究員(カリフォルニア大学サンディエゴ校 バイオエンジニアリング部門、医学部), Japan Society for the Promotion of Science (JSPS), Overseas Research Fellow (Depts. of Bioengineering and Medicine, University of California, San Diego
 
Apr 1994
 - 
May 1996
Research fellow, Japan Society for the Promotion of Science (JSPS)
 

Education

 
Apr 1985
 - 
Mar 1989
Department of Applied Chemistry, Faculty of Science and Engineering, Waseda University
 
Apr 1989
 - 
Mar 1994
Polymer Chemistry, Graduate School, Division of Science and Engineering, Waseda University
 
 
 - 
Oct 2006
医学研究科, 慶應義塾大学
 

Committee Memberships

 
Apr 2015
 - 
Jun 2015
International Society for Artificial Cells, Blood Substitutes, and Immobilization Biotechnology  ISBS 2015 Scientific advisory board member
 
2010
 - 
2011
International Society for Oxygen Transport to Tissues (ISOTT)  Executive Committee Member
 
2009
   
 
International Society for Artificial Cells, Blood Substitutes, and Immobilization Biotechnology  Scientific Advisory Board Member
 

Awards & Honors

 
Nov 2008
向 科学技術振興財団 創立10周年記念 優秀研究
 
Dec 2006
Young Investigator Award of the International Liposome Society (London)
 
Oct 2003
平成15年度JSAO-Grant Yoshimi賞 (日本人工臓器学会)
 
Mar 1994
水野記念学術賞(早稲田大学)
 

Published Papers

 
H. Sakai, C. Leong
Artif. Cells, Nanomed. Biotechnol.   47(1) 3123-3128   Dec 2019   [Refereed]
K. Hagisawa, M. Kinoshita, M. Takikawa, S. Takeoka, D. Saitoh, S. Seki, H. Sakai.
Transfusion   in press    Jul 2019   [Refereed]
Yamada M, Matsuhira T, Yamamoto K, Sakai H.
Biochemistry   58(10) 1400-1410   Mar 2019   [Refereed]
Matsuhira T, Yamamoto K, Sakai H.
Biomacromolecules   20(4) 1592-1602   Feb 2019   [Refereed]
Taguchi K, Nagao S, Maeda H, Yanagisawa H, Sakai H, Yamasaki K, Wakayama T, Watanabe H, Otagiri M, Maruyama T.
Drug Delivery   25(1) 1266-1274   Nov 2018   [Refereed]
S. Ghirmai, L. Bülow, H. Sakai.
Artif. Cells, Nanomedicine, Biotechnol.   46(7) 1364-1372   Nov 2018   [Refereed]
Tatsuya Shonaka, Naoto Matsuno, Hiromichi Obara, Ryo Yoshikawa, Yuji Nishikawa, Mikako Gouchi, Masahide Otani, Hiroyuki Takahashi, Hiroshi Azuma, Hiromi Sakai, Hiroyuki Furukawa
Transplantation Proceedings   50 2821-2825   Nov 2018   [Refereed]
T. Matsuhira, T. Kure, K. Yamamoto, H. Sakai.
Biomacromolecules   19(8) 3412-3420   Aug 2018   [Refereed]
Kohsuke Hagisawa; Manabu Kinoshita; Bonpei Takase; Kenichi Hashimoto; Daizoh Saitoh; Shuhji Seki; Yasuhiro Nishida; Hiromi Sakai
Shock   50(3) 324-330   Mar 2018   [Refereed]

Misc

 
廃棄する血液から人工赤血球をつくる
酒井宏水
コンバーテック   541(46) 20-23   Apr 2018   [Invited]

Books etc

 
ハーパー・生化学 (原書30版) (翻訳)
清水孝雄(監訳)
丸善   Nov 2016   
(第6章) 人工赤血球による生体組織への酸素輸送. 「全人力・科学力・透析力に基づく透析医学」平方秀樹 監修
酒井宏水
医薬ジャーナル社   May 2014   
(Chapter 39) International Consortium for Development of Hemoglobin-Based Oxygen Carriers, Oxygen Therapeutics and Multifunctional Resuscitation Fluids–A White Paper. In: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics (Ed
Hae Won Kim, Jonathan S Jahr, Andrea Mozzarelli and Hiromi Sakai
Springer   Dec 2013   
(Chapter 28) Cellular-Type Hemoglobin-Based Oxygen Carrier as a Resuscitative Fluid for Hemorrhagic Shock: Acute and Long-Term Safety Evaluation Using Beagle Dogs. In: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics (Edito
Tatsuhiko Ikeda, Hirohisa Horinouchi, Yoraro Izumi, Hiromi Sakai and Koichi Kobayashi
Springer   Dec 2013   
(Chapter 22) Biocompatibility of Hemoglobin Vesicles, a Cellular-Type Artificial Oxygen Carrier, on Blood Cells and Plasma Proteins In Vitro and In Vivo. In: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics (Editors, Hae Wo
Hiroshi Azuma, Mitsuhiro Fujihara and Hiromi Sakai
Springer   Dec 2013   

Conference Activities & Talks

 
Translational Research of Artificial Red Cells for a Transfusion Alternative and O2/CO Therapeutics [Invited]
Sakai Hiromi
6th World Congress on Nanomedical Sciences (ISNSCON 2018)   8 Jan 2019   
Present Status of Blood Substitute Research in Japan [Invited]
Sakai Hiromi
Symposium: “Transportador artificial de oxigeno” / Academia Nacional de Medicina de Mexico   14 Nov 2018   
備蓄・緊急投与が可能な人工赤血球製剤の実用化を目指す研究 [Invited]
日本赤十字社 第30回 学術講演会   7 Mar 2018   日本赤十字社
備蓄・緊急投与が可能な人工赤血球製剤 [Invited]
ライフサイエンス 新技術説明会 ~医療系大学~ (JST)   14 Dec 2017   科学技術振興機構
Translational Research of Hb-vesicles (Artificial Red Cells) for a Transfusion Alternative and O2/CO Therapeutics
XVI-International Symposium on Blood Substitutes and Oxygen Therapeutics , Montreal, Canada   15 Nov 2017   
Present Status of Blood Substitute Research in Japan
Hiromi Sakai, Koichi Kobayashi
XVI-International Symposium on Blood Substitutes and Oxygen Therapeutics, Montreal, Canada   14 Nov 2017   
備蓄・緊急投与が可能な人工赤血球製剤
第25回小児ITP研究会   9 Nov 2017   
備蓄・緊急投与が可能な人工赤血球製剤
BioJapan 2017 (medU-net 14機関共同出展アカデミックシーズ発表会)   13 Oct 2017   
Translational Research of Artificial Red Cells (Hemoglobin-Vesicles) for Oxygen and Carbon Monoxide Therapeutics
Hiromi Sakai
The 17th IUPAC International Symposium on MacroMolecular Complexes (MMC-17, Waseda Univ.)   30 Aug 2017   
Hidden antioxidative functions of NADH coexisting with hemoglobin (BIOL 77).
Hiromi Sakai, Magohei Yamada
The 254th ACS National Meeting (Washington DC)   22 Aug 2017   American Chemical Society

Patents

 
特願2016-040494 : ヘモグロビンのメト化抑制能を有する人工赤血球
WO2012137834 A1 : Production method of vesicles
5020525 : 配位子置換型輸液製剤
4763265 : メト化防止剤を含有する人工酸素運搬体
3,466,516 : Stably storable artificial oxygen carriers