論文

査読有り
2018年12月

Effects of oral curcumin ingested before or after eccentric exercise on markers of muscle damage and inflammation

Scandinavian journal of medicine & science in sports
  • Tanabe, Yoko
  • ,
  • Chino, Kentaro
  • ,
  • Ohnishi, Takahiro
  • ,
  • Ozawa, Hitomi
  • ,
  • Sagayama, Hiroyuki
  • ,
  • Maeda, Seiji
  • ,
  • Takahashi, Hideyuki

29
4
開始ページ
524
終了ページ
534
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/sms.13373
出版者・発行元
WILEY

We examined the effect of curcumin (CUR) ingestion before or after exercise on changes in muscle damage and inflammatory responses after exercise. We conducted two parallel experiments with different CUR ingestion timings using a double-blind crossover. In Exp. 1, ten healthy men ingested 180 mg d of CUR or placebo (PLA) 7 days before exercise. In Exp. 2, ten other healthy men ingested 180 mg d of CUR or PLA 7 days after exercise. They performed 30 maximal isokinetic (120°s ) eccentric contractions of the elbow flexors using an isokinetic dynamometer, and this was repeated with the other arm ≥4 weeks later. Maximal voluntary contraction (MVC) torque of the elbow flexors, elbow joint range of motion (ROM), muscle soreness, and serum creatine kinase (CK) activity were measured before, immediately after, and 1-7 days after exercise. Plasma interleukin-8 (IL-8) was measured before, immediately after, 12 hours after, and 1-7 days after exercise. The changes were compared over time. In Exp. 1, no significant differences were found between CUR and PLA subjects for each parameter. However, increases in IL-8 were significantly reduced 12 hours after exercise when CUR was inges

リンク情報
DOI
https://doi.org/10.1111/sms.13373

エクスポート
BibTeX RIS