Kazuo Shiraki - My portal

Profile Information

Affiliation: Visiting Professor, St. Luke's College of Nursing, St. Luke's College of Nursing
: 名誉教授, 鳥取大学

Degree: Doctor(Medicine)(The University of Tokyo)

J-GLOBAL ID: 200901043437665230
researchmap Member ID: 1000303597

Research Interests

Research Areas

Research History

2000 - 2007

聖路加看護大学大学院看護学研究科教授
2007

- 同上客員教授
2000

- Professor, The Graduate School, St. Luke's
1981 - 1999

鳥取大学医学部教授(小児科学)
1981 - 1999

Professor, Department of Pediatrics,
1970 - 1981

Faculty of Medicine, The University of Tokyo
1970 - 1981

Lecturer, Assistant Professor and Associate
1967 - 1969

ロスアンゼルス小児病院リサーチフェロー
1967 - 1969

Research Fellow, Children's Hospital of
1965 - 1967

国立小児病院医員(新生児科)
1965 - 1967

Fellow, National Children's Hospital
1963 - 1965

東京大学医学部助手(小児科)
1963 - 1965

Research Assistant, Department of Pediatrics,
Collage of Nursing
Tottori University
Professor, University of Tokyo
Los Angeles, USA.
University of Tokyo

Education

- 1963

The University of Tokyo
- 1963

Pediatrics, Graduate School, Division of Medical Sciences, The University of Tokyo
- 1958

School of Medicine, Faculty of Medicine, The University of Tokyo
- 1958

Faculty of Medicine, The University of Tokyo

Committee Memberships

2004

功労会員, 日本周産期・新生児医学会
1996 - 2002

監事、名誉会員, 日本肝臓学会
1974 - 2001

運営委員、監事、名誉会員, 日本小児栄養消化器肝臓学会
1996 - 2000

運営委員、名誉会員, 日本小児感染症学会
1994 - 1998

理事,副会長、名誉会員, 日本小児科学会
1984 - 1988

理事、名誉会員, 日本小児保健協会

Awards

Papers

Long-term virological response and growth rate of children with chronic hepatitis C who received natural interferon-alpha

K Shiraki, T Morishima, S Terasawa, M Koike, T Fujisawa, H Tajiri

EUROPEAN JOURNAL OF PEDIATRICS, 161(11) 629-630, Nov, 2002
Prospective reevaluation of risk factors in mother-to-child transmission of hepatitis C virus: High virus load, vaginal delivery, and negative anti-NS4 antibody

M Okamoto, Nagata, I, J Murakami, S Kaji, T Iitsuka, T Hoshika, R Matsuda, Y Tazawa, K Shiraki, S Hino

JOURNAL OF INFECTIOUS DISEASES, 182(5) 1511-1514, Nov, 2000
Evolution in the hypervariable region of hepatitis C virus in infants after vertical transmission

J Murakami, M Okamoto, H Miyata, Nagata, I, K Shiraki, S Hino

PEDIATRIC RESEARCH, 48(4) 450-456, Oct, 2000
Perinatal transmission of hepatitis B virus and its prevention

Kazuo Shiraki

Journal of Gastroenterology and Hepatology (Australia), 15(MAY) E11-E15, 2000
Identification of a novel GC-rich 113-nucleotide region to complete the circular, single-stranded DNA genome of TT virus, the first human circovirus

H Miyata, H Tsunoda, A Kazi, A Yamada, MA Khan, J Murakami, T Kamahora, K Shiraki, S Hino

JOURNAL OF VIROLOGY, 73(5) 3582-3586, May, 1999
Shift of the buoyant of HCV particles in infants infected by mother-to-infant transmission

International Pediatrics, 41 369-373, 1999
Aberrant expression of double-stranded RNA-dependent protein kinase in hepatocytes of chronic hepatitis and differentiated hepatocellular carcinoma

A Shimada, G Shiota, H Miyata, T Kamahora, H Kawasaki, K Shiraki, S Hino, T Terada

CANCER RESEARCH, 58(19) 4434-4438, Oct, 1998
Detection of maternofetal transfusion by placental alkaline phosphatase levels

T Kaneda, K Shiraki, K Hirano, Nagata, I

JOURNAL OF PEDIATRICS, 130(5) 730-735, May, 1997
Virological characteristics of HCV infection in Japanese haemophiliacs

S Takayama, M Taki, T Meguro, K Nishikawa, K Shiraki, K Yamada

HAEMOPHILIA, 3(2) 131-136, Apr, 1997
Pathology of the chronic hepatitis C in children

KAGE M, SHIRAKI K, FUJISAWA T, TAZAWA Y, OKANIWA M, MATSUI A, ETOU T, SUGIYAMA K, UCHIMURA Y

Hepatology, 26(3) 771-775, 1997
Three brothers with progressive hepatic dysfunction and severe hepatic steatosis due to a patent ductus venosus

T Uchino, F Endo, S Ikeda, K Shiraki, Y Sera, Matsuda, I

GASTROENTEROLOGY, 110(6) 1964-1968, Jun, 1996
Mother-to-infants infection by hepatitis B virus and its prevention in Japan

Internat. Hepatology Commun., 5 47-48, 1996
Two Independent outbreaks of measles in partially vaccinated junior high schools in Tottori, Japan

KAWAMOTO A, HONDA T, ISHIDA K, OZEKI T, HAYASHIBARA H, SHIRAKI K, HINO S

Arch Virol, 140(2) 349-354, 1995
Safety and efficacy of a recombinant yeast-derived pre-S2+S-containing hepatitis B vaccine(TGP-943) : Phase 1,2 and 3 clinical testing

Vaccine, 1994
LIVER DYSFUNCTION, ANEMIA, AND GRANULOCYTOPENIA AFTER EXANTHEMA-SUBITUM

T TAKIKAWA, H HAYASHIBARA, Y HARADA, K SHIRAKI

LANCET, 340(8830) 1288-1289, Nov, 1992
MOTHER-TO-INFANT TRANSMISSION OF HEPATITIS-C VIRUS

NAGATA, I, K SHIRAKI, K TANIMOTO, Y HARADA, Y TANAKA, T OKADA

JOURNAL OF PEDIATRICS, 120(3) 432-434, Mar, 1992
THE EFFECT OF HUMAN-MILK ON DNA-SYNTHESIS OF NEONATAL RAT HEPATOCYTES IN PRIMARY CULTURE

Y KOHNO, K SHIRAKI, T MURA

PEDIATRIC RESEARCH, 29(3) 251-255, Mar, 1991
VITAMIN-K ABSORPTION CAPACITY AND ITS ASSOCIATION WITH VITAMIN-K DEFICIENCY

T SHINZAWA, T MURA, M TSUNEI, K SHIRAKI

AMERICAN JOURNAL OF DISEASES OF CHILDREN, 143(6) 686-689, Jun, 1989
HBSAG-POSITIVE GIANT-CELL HEPATITIS WITH CIRRHOSIS IN A 10-MONTH-OLD INFANT

T SHINOZAKI, K SAITO, K SHIRAKI

ARCHIVES OF DISEASE IN CHILDHOOD, 56(1) 64-66, 1981
ACUTE HEPATITIS-B IN INFANTS BORN TO CARRIER MOTHERS WITH THE ANTIBODY TO HEPATITIS-B E-ANTIGEN

K SHIRAKI, N YOSHIHARA, M SAKURAI, T ETO, T KAWANA

JOURNAL OF PEDIATRICS, 97(5) 768-770, 1980

Misc.

Epidemiological survey of Japanese children infected with hepatitis B and C viruses

Toshiyuki Iitsuka, Jun Murakami, Ikuo Nagata, Susumu Kanzaki, Kazuo Shiraki

HEPATOLOGY RESEARCH, 40(9) 878-886, Sep, 2010
Fluctuating liver functions in siblings with MPV17 mutations and possible improvement associated with dietary and pharmaceutical treatments targeting respiratory chain complex II

Shunsaku Kaji, Kei Murayama, Ikuo Nagata, Hironori Nagasaka, Masaki Takayanagi, Akira Ohtake, Hiroyasu Iwasa, Masahiko Nishiyama, Yasushi Okazaki, Hiroko Harashima, Takahiro Eitoku, Michiko Yamamoto, Hiroaki Matsushita, Koichi Kitamoto, Shinji Sakata, Takeshi Katayama, Shuji Sugimoto, Yoshio Fujimoto, Jun Murakami, Susumu Kanzaki, Kazuo Shiraki

MOLECULAR GENETICS AND METABOLISM, 97(4) 292-296, Aug, 2009
Guidelines for care of pregnant women carrying hepatitis C virus and their infants

Kazuo Shiraki, Hitoshi Ohto, Noriyuki Inaba, Tomoo Fujisawa, Hitoshi Tajiri, Susumu Kanzaki, Akira Matsui, Tsuneo Morishima, Kenji Goto, Akihiko Kimura, Shigeo Hino

PEDIATRICS INTERNATIONAL, 50(1) 138-140, Feb, 2008
Five- and 10-year survival rates after surgery for biliary atresia: A report from the Japanese Biliary Atresia Registry

M Nio, R Ohi, T Miyano, M Saeki, K Shiraki, K Tanaka

JOURNAL OF PEDIATRIC SURGERY, 38(7) 997-1000, Jul, 2003
Long-term virological response and growth rate of children with chronic hepatitis C who received natural interferon-alpha

K Shiraki, T Morishima, S Terasawa, M Koike, T Fujisawa, H Tajiri

EUROPEAN JOURNAL OF PEDIATRICS, 161(11) 629-630, Nov, 2002
Prospective reevaluation of risk factors in mother-to-child transmission of hepatitis C virus: High virus load, vaginal delivery, and negative anti-NS4 antibody

M Okamoto, Nagata, I, J Murakami, S Kaji, T Iitsuka, T Hoshika, R Matsuda, Y Tazawa, K Shiraki, S Hino

JOURNAL OF INFECTIOUS DISEASES, 182(5) 1511-1514, Nov, 2000
Evolution in the hypervariable region of hepatitis C virus in infants after vertical transmission

J Murakami, M Okamoto, H Miyata, Nagata, I, K Shiraki, S Hino

PEDIATRIC RESEARCH, 48(4) 450-456, Oct, 2000
Perinatal transmission of hepatitis B virus and its prevention

J Gastr Hepat, 15(Supp.) 11-15, 2000
Identification of a novel GC-rich 113-nucleotide region to complete the circular, single-stranded DNA genome of TT virus, the first human circovirus

H Miyata, H Tsunoda, A Kazi, A Yamada, MA Khan, J Murakami, T Kamahora, K Shiraki, S Hino

JOURNAL OF VIROLOGY, 73(5) 3582-3586, May, 1999
Shift of the buoyant of HCV particles in infants infected by mother-to-infant transmission

International Pediatrics, 41 369-373, 1999
Aberrant expression of double-stranded RNA-dependent protein kinase in hepatocytes of chronic hepatitis and differentiated hepatocellular carcinoma

A Shimada, G Shiota, H Miyata, T Kamahora, H Kawasaki, K Shiraki, S Hino, T Terada

CANCER RESEARCH, 58(19) 4434-4438, Oct, 1998
Detection of maternofetal transfusion by placental alkaline phosphatase levels

T Kaneda, K Shiraki, K Hirano, Nagata, I

JOURNAL OF PEDIATRICS, 130(5) 730-735, May, 1997
Virological characteristics of HCV infection in Japanese haemophiliacs

S Takayama, M Taki, T Meguro, K Nishikawa, K Shiraki, K Yamada

HAEMOPHILIA, 3(2) 131-136, Apr, 1997
Pathology of the chronic hepatitis C in children

Hepatology, 26(3) 771-775, 1997
Three brothers with progressive hepatic dysfunction and severe hepatic steatosis due to a patent ductus venosus

T Uchino, F Endo, S Ikeda, K Shiraki, Y Sera, Matsuda, I

GASTROENTEROLOGY, 110(6) 1964-1968, Jun, 1996
Mother-to-infants infection by hepatitis B virus and its prevention in Japan

Internat. Hepatology Commun., 5 47-48, 1996
Two Independent outbreaks of measles in partially vaccinated junior high schools in Tottori, Japan

Arch Virol, 140(2) 349-354, 1995
SAFETY AND EFFICACY OF A RECOMBINANT YEAST-DERIVED PRE-S2 PLUS S-CONTAINING HEPATITIS-B VACCINE (TGP-943) - PHASE-1, PHASE-2 AND PHASE-3 CLINICAL-TESTING

H SUZUKI, S IINO, K SHIRAKI, Y AKAHANE, H OKAMOTO, K DOMOTO, S MISHIRO

VACCINE, 12(12) 1090-1096, Sep, 1994
LIVER DYSFUNCTION, ANEMIA, AND GRANULOCYTOPENIA AFTER EXANTHEMA-SUBITUM

T TAKIKAWA, H HAYASHIBARA, Y HARADA, K SHIRAKI

LANCET, 340(8830) 1288-1289, Nov, 1992
MOTHER-TO-INFANT TRANSMISSION OF HEPATITIS-C VIRUS

NAGATA, I, K SHIRAKI, K TANIMOTO, Y HARADA, Y TANAKA, T OKADA

JOURNAL OF PEDIATRICS, 120(3) 432-434, Mar, 1992

Books and Other Publications

ナースとコメディカルのための小児科学（第3版）

日本小児医事出版社, 2010
小児消化器肝臓病マニュアル病（監修）（共著）

診断と治療社, 2003
小児科学（第2版）（監修）

医学書院, 2003
Maternal transmission of hepatitis

Hepatolobiliary, Pancreatic and Splenic Disease in Children : Medical and Surgical Management(Elsevier), 1997
Maternal transmission of hepatitis

Hepatolobiliary, Pancreatic and Splenic Disease in Children : Medical and Surgical Management(Elsevier), 1997
Vertical transmission of hepatitis B virus and its prevention in Japan

Viral Hepatitis and Liver Disease(Springer-Verlag), 1994
Vertical transmission of hepatitis B virus and its prevention in Japan

Viral Hepatitis and Liver Disease(Springer-Verlag), 1994
Cholestatic syndromes of infancy and childhood : genetic cholestatic syndromes, neonatal hepatitis, biliary atresia and choledochal cyst of infancy

Hepatology : A Textbook of Liver Disease(W. B. Saunders), 1982
Cholestatic syndromes of infancy and childhood : genetic cholestatic syndromes, neonatal hepatitis, biliary atresia and choledochal cyst of infancy

Hepatology : A Textbook of Liver Disease(W. B. Saunders), 1982
Cholestasis in Infancy. (共著)

Univ. Tokyo Press, 1980
Cholestasis in Infancy. (共著)

Univ. Tokyo Press, 1980

Professional Memberships

Works

C型肝炎ウィルス母子感染に関する研究

1990
Research on the Mother-To-Infant Transmission of Hepatitic C Virus

1990
Ｂ型肝炎母子感染防止事業（厚生省）の創設、推進

白木和夫

Jun, 1985

Research Projects

C型肝炎ウイルスの母子感染に関する研究

厚生労働科学研究費補助金, 1990 - 2007
B型肝炎ウイルスの母子感染とその予防に関する研究

厚生労働科学研究費補助金, 1971 - 2002
Mother-to-Infant Transmission of Hepatitis B Virus and Its Prevention

Health and Labour Sciences Research Grants, 1971 - 2002
Mother-to-Infant Transmission of Hepatitis C virus

Health and Labour Sciences Research Grants, 1990