Takashi Ohtsuki

Profile Information

Affiliation: Assistant Professor, Department of Research Interdisciplinary Graduate School of Medicine and Engineering Life Environment Medical Engineering, University of Yamanashi
: (Concurrent)准教授

Degree: M.Sc.(Shinshu University)
Ph.D.(Shinshu University)
学士（農学）(信州大学)

J-GLOBAL ID: 200901090795254339
researchmap Member ID: 1000304598

External link: http://www.ccn.yamanashi.ac.jp/~tohtsuki/bt4/index.html

Research Interests

Research Areas

Research History

Nov, 2014 - Present

Graduate Faculty of Interdisciplinary Research Faculty of Education, Education (Childhood developmental education), University of Yamanashi
Apr, 2011 - Oct, 2014

Department of Research Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi
Apr, 2007

Department of Research Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi
Apr, 2003

Department of Research Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi
Apr, 1999

Faculty of Engineering, University of Yamanashi
1997 - 1999

The Institute of Medical Science, The University of Tokyo, Researcher
Oct, 1997

The Institute of Medical Science, The University of Tokyo

Education

- 1997

Shinshu University
- 1997

Graduate School, Division of Engineering, Shinshu University
- 1994

Shinshu University
- 1992

Shinshu University
- 1992

Faculty of Textile Science and Technology, Shinshu University

Committee Memberships

Awards

Papers

Effective methane production from the Japanese weed Gyougi-shiba (Cynodon dactylon) is accomplished by colocalization of microbial communities that assimilate water-soluble and -insoluble fractions

Shuhei Matsuda, Takashi Ohtsuki

FEMS Microbiology Letters, 368(4) fnab015, Feb 15, 2021 Peer-reviewedLast authorCorresponding author
Batch-Mode Analysis of Thermophilic Methanogenic Microbial Community Changes in the Overacidification Stage in Beverage Waste Treatment

Shuhei Matsuda, Takahiro Yamato, Yoshiyuki Mochizuki, Yoshinori Sekiguchi, Takashi Ohtsuki

International Journal of Environmental Research and Public Health, 17(20) 7514-7514, Oct 15, 2020 Peer-reviewedLast authorCorresponding author
Establishment and analysis of microbial communities capable of producing methane from grass waste at extremely high C/N ratio.

Matsuda S, Ohtsuki T

International Journal of New Technology and Research, 2(9) 81-86, Sep, 2016 Peer-reviewedLast authorCorresponding author
Ion detection by intramolecular charge-transfer absorption of benzocrown-bipyridinium conjugate appending octadecyl chain.

Kuwabara T, Satake R, Guo H, Katsumata M, Takahashi M, Suzuki Y, Ohtsuki T, Sato T, Kurokawa H

Journal of Ion Exchange, 27(2) 27-32, May, 2016 Peer-reviewed
Acceleration of removal of high concentration-phenol by activated sludge with nitrate-oxidized lignite.

Ohtsuki T, Hanagata M, Masuda T, Ui S

Japanese Journal of Water Treatment Biology, 51(2) 37-47, Jun, 2015 Peer-reviewedLead author
Modification of Chimeric (2S, 3S)-butanediol Dehydrogenase Based on Structural Information

Tomohito Shimegi, Kaito Mochizuki, Takuji Oyama, Takashi Ohtsuki, Masami Kusunoki, Sadaharu Ui

PROTEIN AND PEPTIDE LETTERS, 22(3) 226-233, 2015 Peer-reviewed
Streptomyces hokutonensis sp. nov., a novel actinomycete isolated from the strawberry root rhizosphere

Hideki Yamamura, Haruna Ashizawa, Moriyuki Hamada, Akira Hosoyama, Hisayuki Komaki, Misa Otoguro, Tomohiko Tamura, Yukikazu Hayashi, Youji Nakagawa, Takashi Ohtsuki …

JOURNAL OF ANTIBIOTICS, 67(6) 465-470, Jun, 2014 Peer-reviewed
Crystallization and preliminary X-ray diffraction analysis of domain-chimeric L-(2S,3S)-butanediol dehydrogenase

Tomohito Shimegi, Takuji Ooyama, Takashi Ohtsuki, Genji Kurisu, Masami Kusunoki, Sadaharu Ui

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 70(4) 461-463, Apr, 2014 Peer-reviewed
Crystallization and preliminary X-ray diffraction analysis of domain-chimeric l-(2S,3S)-butanediol dehydrogenase

Tomohito Shimegi, Takuji Ooyama, Takashi Ohtsuki, Genji Kurisu, Masami Kusunoki, Sadaharu Ui

Acta Crystallographica Section F:Structural Biology Communications, 70(4) 461-463, 2014 Peer-reviewed
X-ray crystallographic analysis of domain-chimeric L-(2S,3S)-butanediol dehydroggenase

T. SHimegi, T. Ooyama, T. Ohtsuki, M. Kusunoki, S. Ui

Photon Factory Activity Report, 2013 #31B, 2013
Construction of a Tailor-Made L (2S, 3S)-Butanediol Dehydrogenase by Exchanging Domains Between Native Structural Analogs

Tomohito Shimegi, Yuhsuke Takusagawa, Takashi Ohtsuki, Satoko Noda, Genji Kurisu, Masami Kusunoki, Sadaharu Ui

PROTEIN AND PEPTIDE LETTERS, 18(8) 825-830, Aug, 2011 Peer-reviewed
Chitin nanowhiskers mediate transformation of Escherichia coli by exogenous plasmid DNA

Mera A, Araki J, Ohtsuki T, Shimosaka M, Yoshida N

Journal of Biotechnology and Biomaterials, 1(6) 114, 2011 Peer-reviewed
Improvemnet of bioconversion suitability of Japanese cypress wood by combination of UV radiation, ozonization and decay treatment with white-rot and brown-rot fungi

Ohtsuki T, Noda S, Ui S

Canadian Journal of Pure and Applied Sciences, 5(1) 1333-1343, 2011 Peer-reviewedLead author
Structural basis for chiral substrate recognition by two 2,3-butanediol dehydrogenases

Masato Otagiri, Sadaharu Ui, Yuhsuke Takusagawa, Takashi Ohtsuki, Genji Kurisu, Masami Kusunoki

FEBS LETTERS, 584(1) 219-223, Jan, 2010 Peer-reviewed
High-yield Production of Scutellaria Radix Flavonoids (Baicalein, Baicalin and Wogonin) by Liquid-culture of Scutellaria baicalensis Root-derived Cells

Takashi Ohtsuki, Mika Himeji, Harumi Fukazawa, Miho Tanaka, Hisako Yamamoto, Akio Mimura

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, 52(2) 291-298, Mar, 2009 Peer-reviewedLead author
Development of activated sludge adapted to high concentrations of phenol and enhancement of its phenol removal ability by addition of a processed lignite

Takashi Ohtsuki, Kazuki Sakurai, Satoko Noda, Joji Ichihara, Takahito Masuda, Sadaharu Ui

Indian Journal of Science and Technology, 2(10) 1-4, 2009 Peer-reviewedLead author
Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell

Mika Himeji, Takashi Ohtsuki, Harumi Fukazawa, Miho Tanaka, Shin-ichi Yazaki, Sadaharu Ui, Koji Nishio, Hisako Yamamoto, Kachio Tasaka, Akio Mimura

CANCER LETTERS, 245(1-2) 269-274, Jan, 2007 Peer-reviewed
Production of large multienzyme complex by aerobic thermophilic fungus Chaetomium sp nov MS-017 grown on palm oil mill fibre

T Ohtsuki, Suyanto, S Yazaki, S Ui, A Mimura

LETTERS IN APPLIED MICROBIOLOGY, 40(2) 111-116, 2005 Peer-reviewedLead author
Production of L-2,3-butanediol by a new pathway constructed in Escherichia coli

S Ui, Y Takusagawa, T Sato, T Ohtsuki, A Mimura, M Ohkuma, T Kudo

LETTERS IN APPLIED MICROBIOLOGY, 39(6) 533-537, 2004 Peer-reviewed
Induction of apoptosis in human leukemia cells by naturally fermented sugar cane vinegar (kibizu) of Amami Ohshima Island

A Mimura, Y Suzuki, Y Toshima, S Yazaki, T Ohtsuki, S Ui, F Hyodoh

BIOFACTORS, 22(1-4) 93-97, 2004 Peer-reviewed

Misc.

3P-174 Progression of wood biodegradability for hydrogen-/methane fermentation by retreatment of mushroom culture substrate with edible mushrooms

Osada Moyuru, Ohtsuki Takashi, Ui Sadaharu

66 238-238, 2014
3P-172 Agrobacterium tumefaciens-mediated transformation of white-rot fungus Ceriporiopsis subvermispora

Suzuki Ami, Ohtsuki Takashi, Ui Sadaharu

66 237-237, 2014
2P-127 Isolation of the commensal bacterium enhancing growth and oil production of Botryococcus braunii

Ohtsuki Takashi, Sugauchi Yuichiro, Ui Sadaharu

66 138-138, 2014
バイオマスの有効利用を妨げる渋滞問題

大槻隆司

日本生物工学会誌, 90(2) 93-93, 2012 Invited
ブランチスピリット・東日本支部の生物工学教育活動(1) 〜学生発表討論会〜

大槻隆司

日本生物工学会誌, 88(1) 28-29, 2010 Invited
水素利用インフラ整備は微生物界でも大変!?

大槻隆司

日本生物工学会誌, 87(3) 135-135, 2009 Invited
”自由研究は面白い”に誘う私の工夫ー生徒の興味との接点を探すー

大槻隆司

楽しい理科授業, 38(7) 7, 2006 Invited
2G11-5 Development of biological control system for repressing basal stem cell rotting mushroom Ganoderma spp. on oil palm trees

NAKANO Masako, AKIZUMI Hironobu, AHKAM Subroto, YAZAKI Shinichi, OHTSUKI Takashi, UI Sadaharu, MIMURA Akio

16 200-200, 2004
3K10-1 Utilization of palm oil mill fiber in situ bioactivator process by Chaetomium sp. nov. MS-017 :

Suyanto, Ohtsuki Takashi, Yazaki Shinichi, Ui Sadaharu, Mimura Akio

15 227-227, 2003
Characterization of xylanosome produced by Chaetomium sp. nov. MS-017 on solid state fermentation of palm oil mill fiber

Ohtsuki Takashi, Suyanto, Yazaki Shinichi, Ui Sadaharu, Mimura Akio

15 113-113, 2003
314 Enzymes decomposing palm oil mill fiber in fungus Ms-017 under higher temperature :

Suyanto, Yazaki Shin-ichi, Ohtsuki Takashi, Ui Sadaharu, Mimura Akio

13 168-168, 2001
Enzyme production from rice straw using fungus under higher temperature.

Ohtsuki Takashi, Suyanto, Yazaki Shin-ichi, Ui Sadaharu, Mimura Akio

13 168-168, 2001
Good or evil: CD26 and HIV infection

T Ohtsuki, H Tsuda, C Morimoto

JOURNAL OF DERMATOLOGICAL SCIENCE, 22(3) 152-160, Apr, 2000 InvitedLead author
1027 Isolation and cultivation of fungi on palm oil mill fiber under higher temperature :

Suyanto, Yazaki Shin-ichi, Ohtsuki Takashi, Ui Sadaharu, Mimura Akio

12 246-246, 2000
Fungous decomposition of rice straw under higher temperature

Ohtsuki Takashi, Suyanto, Yazaki Shin-ichi, Ui Sasaharu, Mimura Akio

12 246-246, 2000
Core 2-containing O-glycans on CD43 are preferentially expressed in the memory subset of human CD4 T cells

R Mukasa, T Homma, T Ohtsuki, O Hosono, A Souta, T Kitamura, M Fukuda, S Watanabe, C Morimoto

INTERNATIONAL IMMUNOLOGY, 11(2) 259-268, Feb, 1999

Books and Other Publications

ファイバー・スーパーバイオミメティックス

(Role: Contributor, オンサイトでの燃料電池発電のための水素生産ユニット－バイオによる家庭用燃料生産システムの現状と課題－)

（株）エヌ・ティー・エス, 2006
Utilization of tropical biomass from plantations to produce useful materials for sustainable development of Indonesia. II. Development of in-field composting system by solid state fermentation process with thermophilic fungus for sustainable prosperit・・・

2005
Utilization of tropical biomass from plantations to produce useful materials for sustainable development of Indonesia. I. Biomass utilization of oil palm plantations in Indonesia: present status, problems and prospects

2005
Utilization of tropical biomass from plantations to produce useful materials for sustainable development of Indonesia. II. Development of rapid decomposition process of palm oil mill wastes

2004
Utilization of tropical biomass from plantations to produce useful materials for sustainable development of Indonesia. I. Biomass utilization of oil palm plantations in Indonesia: present status, problems and prospects

2004
Development of in situ bioactivator process on palm oil mill fiber by Chaetomium sp. nov. MS-017

2003
Integrated development of biomass plantations for energy, and commodity and fine chemicals

2002
Composting of palm oil mill fiber by fungi under higher temperature

2001

Presentations

活性汚泥処理能力に及ぼす腐植酸の影響

2011年度日本生物工学会若手研究者の集い夏のセミナー, 2011
改変型2,3-butanediol dehydrogenaseの立体構造解析

2011年度日本生物工学会若手研究者の集い夏のセミナー, 2011
微小化セルロースを資化する微生物群の菌相解析

平成22年度日本生物工学会大会, 2010
UV/オゾン処理と白色・褐色腐朽菌を用いた腐朽処理の組合せによるヒノキ材易利用化の検討

2010年度日本農芸化学会関東支部大会, 2010
木質資源の直接微生物変換効率化のための腐朽処理条件の検討

2010年度日本農芸化学会大会, 2010
高フェノール濃度馴化活性汚泥への腐植酸添加によるフェノール除去能の促進

2009年度日本農芸化学会関東支部大会, 2009
木質バイオマスへの糖化酵素作用性を高める処理条件の検討

2009年度日本農芸化学会大会, 2009
Subdomain chimeraによる有用SDRの創製とその立体構造

2008年度日本農芸化学会関東支部大会, 2008
セルロース分解微生物群制御をめざした機能微生物解析

2008年度日本農芸化学会大会, 2008
水素生産複合系における機能微生物の解析

2007年度日本農芸化学会大会, 2007
パーム油搾油粕の高温糸状菌固体醗酵による抗菌性物質の生産

２００６年度日本農芸化学会大会, 2006
インドネシアジャムーによるヒトマクロファージ様細胞活性化

２００６年度日本農芸化学会大会, 2006
拮抗微生物を活用したマンゴー炭疽病菌の予防的抑制

２００６年度日本農芸化学会大会, 2006
Microbial biotechnology for sustainable agriculture of peat land

9th National Congress of Indonesian Society for Microbiology & 3rd Asian Conference for Lactic Acid Bacteria, 2005
Modification of peat soil of Kalimantan by solid state fermentation of soil microorganisms and plant biomass

9th National Congress of Indonesian Society for Microbiology & 3rd Asian Conference for Lactic Acid Bacteria, 2005
ヒト二倍体細胞を用いる紫外線傷害評価法の構築と沖縄薬膳素材、抗酸化ビタミンへの応用

第１２回日本がん予防研究会・第２８回日本がん疫学研究会, 2005
Construction of hybrid microbial consortium for production of bio-hydrogen from tropical biomass

The 3rd Indonesian Biotechnology Conference, 2004
Development of bioactivator process on empty fruit bunches by indigenous microbial consortium

The 3rd Indonesian Biotechnology Conference, 2004
Elucidation of tropical health food factors by analyzing radical scavenging activity for the prevention of life style-related diseases

The 3rd Indonesian Biotechnology Conference, 2004
Production of xylanase complex and antifungal compounds by solid state fermentation of palm oil mill fiber using Chaetomium sp. nov. MS-017

The 3rd Indonesian Biotechnology Conference, 2004

Professional Memberships

Research Projects

Biohydrogen production from wheat straw enhanced by starch addition

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

OHTSUKI Takashi
Direct conversion of plant biomass to isoprene by microorganisms expressing cell-wall degrading enzymes from parasitic plants

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2012

OKAZAWA Atsushi, OHTSUKI Takashi
Utilization of network in microbial community
Utilization of biomass resources
Utilization of various functions of microorganisms
Production of useful compounds
複合微生物系構造・機能の解明と応用
バイオマスの有効利用
微生物機能の高度利用
代謝工学･遺伝子工学手法を用いた有用物質生産
Analysis and Utilization of Function of Microbial Community
Biological Degradation of Artificial Chemicals
Biological conversion of Waste Biomass to Valuable Products

Industrial Property Rights

特願2018-019985 セリ科植物の種子を高効率で発芽させる方法、そのためのキット及びその製造方法

大槻隆司
特開2012-39948 キノコ廃菌床を再利用した菌床

宇井定春, 中島俊, 大槻隆司, 野田悟子

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Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Presentations

Professional Memberships

Research Projects

Industrial Property Rights

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