2003年7月
Rod-driven focal macular electroretinogram
JAPANESE JOURNAL OF OPHTHALMOLOGY
- ,
- ,
- 巻
- 47
- 号
- 4
- 開始ページ
- 356
- 終了ページ
- 361
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/S0021-5155(03)00073-X
- 出版者・発行元
- ELSEVIER SCIENCE INC
Purpose: To determine the stimulus conditions required to elicit rod-driven, focal macular electroretinograms (rod FMERGs).
Methods: A blue (lambda(max) = 470 nm) stimulus, 5degrees in size, was imaged at a luminance of 1.5 cd/m(2) on different regions of the human retina. Electroretinograms (ERGS) elicited by this stimulus were recorded from the light- and dark-adapted retina of four subjects without any ophthalmological abnormalities. A subject with cone dystrophy was also tested by this method.
Results: Stimulus luminance : 1.5 cd/m(2) did not elicit a response when it was imaged on the optic disc, but higher intensities elicited a small b-wave from stray light. When this stimulus was imaged on the macular area or the 15degrees temporal retina, an ERG was elicited that had the shape of the full-field scotopic ERG. This stimulus with a luminance of 1.5 cd/m(2) did not elicit a response from stimulation of the macular area of a light-adapted retina but elicited a slow-rising positive b-wave after 30 minutes of dark adaptation. In a subject with cone dystrophy, focal rod response was elicited from the macula, despite no response under photopic conditions.
Conclusion: We conclude that this stimulus will elicit a response that is derived exclusively from rods and is a focal response with no contribution from stray light. (C) 2003 Japanese Ophthalmological Society.
Methods: A blue (lambda(max) = 470 nm) stimulus, 5degrees in size, was imaged at a luminance of 1.5 cd/m(2) on different regions of the human retina. Electroretinograms (ERGS) elicited by this stimulus were recorded from the light- and dark-adapted retina of four subjects without any ophthalmological abnormalities. A subject with cone dystrophy was also tested by this method.
Results: Stimulus luminance : 1.5 cd/m(2) did not elicit a response when it was imaged on the optic disc, but higher intensities elicited a small b-wave from stray light. When this stimulus was imaged on the macular area or the 15degrees temporal retina, an ERG was elicited that had the shape of the full-field scotopic ERG. This stimulus with a luminance of 1.5 cd/m(2) did not elicit a response from stimulation of the macular area of a light-adapted retina but elicited a slow-rising positive b-wave after 30 minutes of dark adaptation. In a subject with cone dystrophy, focal rod response was elicited from the macula, despite no response under photopic conditions.
Conclusion: We conclude that this stimulus will elicit a response that is derived exclusively from rods and is a focal response with no contribution from stray light. (C) 2003 Japanese Ophthalmological Society.
- リンク情報
-
- DOI
- https://doi.org/10.1016/S0021-5155(03)00073-X
- CiNii Articles
- http://ci.nii.ac.jp/naid/10013678466
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/12842203
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000184085700006&DestApp=WOS_CPL
- ID情報
-
- DOI : 10.1016/S0021-5155(03)00073-X
- ISSN : 0021-5155
- CiNii Articles ID : 10013678466
- PubMed ID : 12842203
- Web of Science ID : WOS:000184085700006