2003年
Rod-driven focal macular electroretinogram
Japanese Journal of Ophthalmology
- ,
- ,
- 巻
- 47
- 号
- 4
- 開始ページ
- 356
- 終了ページ
- 361
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/S0021-5155(03)00073-X
- 出版者・発行元
- Elsevier Inc.
Purpose: To determine the stimulus conditions required to elicit rod-driven, focal macular electroretinograms (rod FMERGs). Methods: A blue (λmax = 470 nm) stimulus, 5° in size, was imaged at a luminance of 1.5 cd/m2 on different regions of the human retina. Electroretinograms (ERGs) elicited by this stimulus were recorded from the light- and dark-adapted retina of four subjects without any ophthalmological abnormalities. A subject with cone dystrophy was also tested by this method. Results: Stimulus luminance ≦1.5 cd/m2 did not elicit a response when it was imaged on the optic disc, but higher intensities elicited a small b-wave from stray light. When this stimulus was imaged on the macular area or the 15° temporal retina, an ERG was elicited that had the shape of the full-field scotopic ERG. This stimulus with a luminance of 1.5 cd/m2 did not elicit a response from stimulation of the macular area of a light-adapted retina but elicited a slow-rising positive b-wave after 30 minutes of dark adaptation. In a subject with cone dystrophy, focal rod response was elicited from the macula, despite no response under photopic conditions. Conclusion: We conclude that this stimulus will elicit a response that is derived exclusively from rods and is a focal response with no contribution from stray light. © 2003 Japanese Ophthalmological Society.
- リンク情報
- ID情報
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- DOI : 10.1016/S0021-5155(03)00073-X
- ISSN : 0021-5155
- CiNii Articles ID : 10013678466
- PubMed ID : 12842203
- SCOPUS ID : 0037709008