Papers

Peer-reviewed International journal
Jun 18, 2018

Vector competence of Haemaphysalis longicornis ticks for a Japanese isolate of the Thogoto virus.

Scientific reports
  • Melbourne Rio Talactac
  • ,
  • Kentaro Yoshii
  • ,
  • Emmanuel Pacia Hernandez
  • ,
  • Kodai Kusakisako
  • ,
  • Remil Linggatong Galay
  • ,
  • Kozo Fujisaki
  • ,
  • Masami Mochizuki
  • ,
  • Tetsuya Tanaka

Volume
8
Number
1
First page
9300
Last page
9300
Language
English
Publishing type
Research paper (scientific journal)
DOI
10.1038/s41598-018-27483-1

Thogoto virus (THOV), a tick-borne arbovirus not previously reported in East Asia, was recently isolated from Haemaphysalis longicornis in Kyoto, Japan. In this study, we investigated the vector competence of H. longicornis ticks for a Japanese isolate of the Thogoto virus using anal pore microinjection and experimental virus acquisition. Our results showed that anal pore microinjection can readily infect adult ticks, and THOV-infected ticks can successfully transmit the virus to mice. Blood feeding was also critical in the distribution of the virus in tick organs, most especially in the salivary glands. Furthermore, co-feeding between an infected adult and naïve nymphs can also produce infected molted adults that can horizontally transmit THOV to mice. Altogether, our results suggest that H. longicornis is a competent vector for the Japanese THOV isolate and could be the primary tick vector of the virus in Japan.

Link information
DOI
https://doi.org/10.1038/s41598-018-27483-1
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29915199
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006283
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000435448300043&DestApp=WOS_CPL
ID information
  • DOI : 10.1038/s41598-018-27483-1
  • ISSN : 2045-2322
  • Pubmed ID : 29915199
  • Pubmed Central ID : PMC6006283
  • Web of Science ID : WOS:000435448300043

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