HOSOYA Ken-ichi

J-GLOBAL         Last updated: Aug 30, 2018 at 18:29
HOSOYA Ken-ichi
University of Toyama
Faculty of Pharmacy and Pharmaceutical Sciences, School of Pharmacy
(BLANK), Ph.D.

Research Areas


Academic & Professional Experience

Apr 2006
Professor, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
Oct 2013
Mar 2018
Dean, Faculty of Pharmaceutical Sciences, University of Toyama
Oct 2009
Sep 2013
Associate Dean, Faculty of Pharmaceutical Sciences, University of Toyama
Oct 2005
Mar 2006
Professor, Faculty of Pharmaceutical Sciences, University of Toyama
Oct 2000
Sep 2005
Professor, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University


Apr 1983
Mar 1985
Graduate School of Pharmaceutical Sciences, Josai University
Apr 1979
Mar 1983
Pharmacy, Faculty of Pharmaceutical Sciences, Josai University

Awards & Honors

Nov 2009
Fellow, American Association of Pharmaceutical Scientists

Published Papers

Tachikawa M, Toki H, Watanabe M, Tomi M, Hosoya KI, Terasaki T
Anatomical science international   93(4) 456-463   Sep 2018   [Refereed]
Kinoshita Y, Nogami K, Jomura R, Akanuma SI, Abe H, Inouye M, Kubo Y, Hosoya KI
Molecular pharmaceutics   15(8) 3583-3594   Aug 2018   [Refereed]
Akanuma SI, Yamakoshi A, Sugouchi T, Kubo Y, Hartz AMS, Bauer B, Hosoya KI
Molecular pharmaceutics   15(6) 2327-2337   Jun 2018   [Refereed]
Kubo Y, Akanuma SI, Hosoya KI
Expert opinion on drug metabolism & toxicology   14(5) 513-531   May 2018   [Refereed]
Tachikawa M, Hirose S, Akanuma SI, Matsuyama R, Hosoya KI
Microvascular research   117 16-21   May 2018   [Refereed]
Kubo Y, Nakazawa A, Akanuma SI, Hosoya KI
Pharmaceutical research   35(5) 93   Mar 2018   [Refereed]
Akanuma SI, Higashi H, Maruyama S, Murakami K, Tachikawa M, Kubo Y, Hosoya KI
Experimental eye research   168 128-137   Mar 2018   [Refereed]
Tachikawa M, Watanabe M, Fukaya M, Sakai K, Terasaki T, Hosoya KI
Neurochemical research   43(2) 500-510   Feb 2018   [Refereed]
Tachikawa M, Yashiki A, Akanuma SI, Matsukawa H, Ide S, Minami M, Hosoya KI
Neurochemistry international   113 1-7   Feb 2018   [Refereed]
Akanuma SI, Yamazaki Y, Kubo Y, Hosoya KI
Fluids and barriers of the CNS   15(1) 1   Jan 2018   [Refereed]


Chem. Pharm. Bull.   36(9) 3702-3705   1988
Effect of Azone concentration and solvents on the skin permeation of 5-fluorouracil and indomethacin,
Yakuzaigaku   51 80-86   1991
J. Pharm. Sci.   81(1) 58-64   1992
Kenichi HOSOYA, Hiroyuki KUBO, Hideshi NATSUME, Kenji SUGIBAYASHI, Yasunori MORIMOTO
Biol. Pharm. Bull.   17(2) 316-322   1994
Design and evaluation of sustained-release granules of sodium valproate
Yakuzaigaku   54 49-54   1994
Pharmacokinetics of valproic acid after oral administration of sustained-release granules of sodium valproate in human
Yakuzaigaku   54 55-60   1994
Contribution of Na+-glucose cotransport to the short-circuit current in th e pigmented rabbit conjunctiva
Curr. Eye Res.   15 447-451   1996
Curr. Eye Res.   16 693-697   1997
Nucleoside transport mechanisms in the pigmented rabbit conjunctiva
Invest. Ophthalmol. Vis. Sci.   39 372-377   1998
Carrier-mediated transport of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, in the pigmented rabbit conjunctiva
J. Pharmacol. Exp. Ther.   285 223-227   1998
Carrier-mediated transport of monocarboxylate transport in the pigmented rabbit conjunctiva
Invest. Ophthalmol. Vis. Sci.   39 1436-1443   1998
Nucleotide stimulation of net Cl- secretion in the rabbit conjunctiva
J. Pharmacol. Exp. Ther.   291 53-59   1999
mRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines ; a new in vitro BBB model for drug targeting
J Drug Targeting   8(357-370)    2000
Conditionally immortalized brain capillary endothelial cell lines established from transgenic mouse harboring temperature-sensitive SV 40 large T-antigen gene
AAPS Pharm Sci.(http : //www.pharmsci.org)   2(Article 27)    2000
GAT2/BGT-1 as a system responsible for the transport of g-aminobutyric acid at the mouse blood-brain barrier
J. Cereb. Blood Flow Metab.   21, 1232-1239    2001
Newly developed rat brain pericyte cell line, TR-PCT1, responds to transforming growth factor-b1 and b-glycerophosphate
Eur. J. Cell Biol.   81, 145-152    2002
Induction of the xCT gene expression and L-cystine transport activity by diethyl maleate at the inner blood-retinal barrier
Invest. Ophthalmol. Vis. Sci.   43, 774-779    2002
The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the bra
J. Cereb. Blood Flow Metab.   22, 1327-1335    2002

Books etc

Drug delivery to the posterior segment. IN Retina, 3rd Edition
Mosby, St. Louis   2001   
Brain barrier function : its analysis and reconstitution. IN Tissue Engineering for Therapeutic Use 4
Elsevier, Amsterdam   2000   
The brain efflux index method(BEI). IN Brain barrier Systems, Alfred Benzon Symposium 45
Munksgaard, Copenhagen   1999   

Research Grants & Projects

Transport mechanism at the blood-retinal barrier