論文

査読有り
2012年5月

Economic evaluation of vaccination programme of 7-valent pneumococcal conjugate vaccine to the birth cohort in Japan

VACCINE
  • Shu-ling Hoshi
  • ,
  • Masahide Kondo
  • ,
  • Ichiro Okubo

30
22
開始ページ
3320
終了ページ
3328
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.vaccine.2012.02.033
出版者・発行元
ELSEVIER SCI LTD

Aiming to introduce 7-valent pneumococcal conjugate vaccine (PVC-7) into routine vaccination schedule, the government of Japan gives a temporary budget to encourage municipalities in launching public vaccination programme which started on November 26, 2010 and ends on March 31, 2012. This study aims to appraise the 'value for money' of PCV-7 vaccination programme from the societal perspective and the budget impact from the perspective of municipalities, which is responsible for providing routine vaccination.
We conducted a cost-effectiveness analysis with Markov modelling and calculated incremental cost-effectiveness ratio (ICER) value of launching such programme with two levels of co-payment, (sic)1000 (US$13) or (sic)0, and two scenarios of the uptake of vaccine (vaccinated-alone or co-vaccinated with other vaccines).
We found that when vaccinated-alone, ICERs in QALY were (sic)7,441,000 (US$93,013) or (sic)9,065,000 (US$113,313), and when co-vaccinated (sic)7,441,000 (US$93,013) or (sic)5,489,000 (US$68,613), without or with productivity loss, respectively, regardless of co-payment level of the programme. Co-vaccinated programmes had lower ICER than vaccinated-alone programmes due to the savings in productivity loss. By adopting WHO's classification that an intervention is 'cost-effective' if ICER (in QALY) is between 1 and 3 times of GDP as a criterion, PCV-7 vaccination programme in Japan is concluded as "cost-effective" from the perspective of society.
The introduction of either no co-payment or (sic)1000 (US$13) co-payment vaccination programme appears to be not budget saving for the first 6 years, whereas the level of budget impact are less than (sic)11,000,000 (US$137,500) or (sic)8,500,000 (US$106,250), respectively, for a municipality with 1000 birth cohort in the 1st year and 2nd to 5th year birth cohort proportional to the birth cohort population of estimated future population. (c) 2012 Elsevier Ltd. All rights reserved.

Web of Science ® 被引用回数 : 13

リンク情報
DOI
https://doi.org/10.1016/j.vaccine.2012.02.033
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000303905000010&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.vaccine.2012.02.033
  • ISSN : 0264-410X
  • Web of Science ID : WOS:000303905000010

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