豊島秀男 (Hideo Toyoshima) - マイポータル - researchmap

基本情報

所属: 自治医科大学附属さいたま医療センター准教授

学位: 医学博士(東京大学)

J-GLOBAL ID: 200901004795829435
researchmap会員ID: 1000312827

研究分野

2

経歴

2

1990年 - 1996年

東京大学医学部助手
1990年 - 1996年

Assistant Professor, Faculty of Medicine,University of Tokyo

学歴

2

- 1985年

東京大学, 医学部, 医
- 1985年

東京大学

MISC

14

Smad-mediated Transcription Is Required for Transforming Growth Factor-β1-induced p57Kip2 Proteolysis in Osteoblastic Cells

NISHIMORI S, TANAKA Y, CHIBA T, FUJII M, MIYAZONO K, OGASAWARA T, KAWAGUCHI H, IGARASHI T, TOYOSHIMA H

The Journal of Biological Chemistry 276(14) 10700-10705 2001年4月
Smad-mediated transcription is required for transforming growth factor-beta 1-induced p57(Kip2) proteolysis in osteoblastic cells

S Nishimori, Y Tanaka, T Chiba, M Fujii, T Imamura, K Miyazono, T Ogasawara, H Kawaguchi, T Igarashi, T Fujita …

JOURNAL OF BIOLOGICAL CHEMISTRY 276(14) 10700-10705 2001年4月
p57Kip2 is degraded through the proteasome in osteoblasts stimulated to proliferation by transforming growth factor β1.

URANO T, YASHIRODA H, MURAOKA M, TANAKA K, HOSOI T, INOUE S, OUCHI Y, TANAKA K, TOYOSHIMA H

Journal of Biological Chemistry 274(18) 12197-12200 1999年4月
p57(Kip2) is degraded through the proteasome in osteoblasts stimulated to proliferation by transforming growth factor beta 1

T Urano, H Yashiroda, M Muraoka, K Tanaka, T Hosoi, S Inoue, Y Ouchi, K Tanaka, H Toyoshima

JOURNAL OF BIOLOGICAL CHEMISTRY 274(18) 12197-12200 1999年4月
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage

RYC Poon, W Jiang, H Toyoshima, T Hunter

JOURNAL OF BIOLOGICAL CHEMISTRY 271(22) 13283-13291 1996年5月
Role of cyclin A and p27 in anti-IgM-induced G(1) growth arrest of murine B-cell lymphomas

SA Ezhevsky, H Toyoshima, T Hunter, DW Scott

MOLECULAR BIOLOGY OF THE CELL 7(4) 553-564 1996年4月
Inctivation of p27Kip1 by the viral E1A oncoprotein in TGF β-treated cells.

MAL A, POON R Y C, HOWE P H, TOYOSHIMA H, HUNTER T, HARTER M L

Nature 380(6571) 262-265 1996年3月
Inactivation of p27(Kip1) by the viral E1A oncoprotein in TGF beta-treated cells

A Mal, RYC Poon, PH Howe, H Toyoshima, T Hunter, ML Harter

NATURE 380(6571) 262-265 1996年3月
Redistribution of the CDK inhibitor p27 between different cyclin・CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation.

Molecular Biology of the Cell 6(9) 1197-1213 1995年9月
REDISTRIBUTION OF THE CDK INHIBITOR P27 BETWEEN DIFFERENT CYCLIN-CENTER-DOT-CDK COMPLEXES IN THE MOUSE FIBROBLAST CELL-CYCLE AND IN CELLS ARRESTED WITH LOVASTATIN OR ULTRAVIOLET-IRRADIATION

RYC POON, H TOYOSHIMA, T HUNTER

MOLECULAR BIOLOGY OF THE CELL 6(9) 1197-1213 1995年9月
P27, A NOVEL INHIBITOR OF G1 CYCLIN-CDK PROTEIN-KINASE ACTIVITY, IS RELATED TO P21

H TOYOSHIMA, T HUNTER

CELL 78(1) 67-74 1994年7月
Differently spliced cDNAs of human ltk receptor tyrosine kinase predict receptor proteins with and without tyrosine kinase domain and a soluble receptor protein.

TOYOSHIMA H, KOZUTSUMI H, MARU Y, HAGIWARA K, FURUYA A, MIOH H, HANAI N, TAKAKU F, HIRAI H

Proceedings of the National Academy of Sciences of the United States of America 90(12) 5404-5408 1993年
Differently spliced cDNAs of human ltk receptor tyrosine kinase predict receptor proteins with and without tyrosine kinase domain and a soluble receptor protein.

Proceedings of the National Academy of Sciences of the United States of America 90(12) 5404-5408 1993年
SECONDARY STRUCTURE OF THE HUMAN T-CELL LEUKEMIA-VIRUS TYPE-1 REX-RESPONSIVE ELEMENT IS ESSENTIAL FOR REX-REGULATION OF RNA PROCESSING AND TRANSPORT OF UNSPLICED RNAS

H TOYOSHIMA, M ITOH, JI INOUE, M SEIKI, F TAKAKU, M YOSHIDA

JOURNAL OF VIROLOGY 64(6) 2825-2832 1990年6月

所属学協会

5

共同研究・競争的資金等の研究課題

2

動脈硬化における細胞分化と細胞周期

その他の研究制度
Cell Differentiation and Cell Cycle in Atherosclerosis

The Other Research Programs