TAKAHASHI Noriko

J-GLOBAL         Last updated: Dec 31, 2018 at 13:18
 
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Name
TAKAHASHI Noriko
Affiliation
The University of Tokyo
Section
Graduate School of Medicine Center for Disease Biology and Integrative Medicine, Okazaki National Research Institutes (Institute for Physiological Sciences) Cell Physiology
Job title
Research Associates

Research Areas

 
 

Academic & Professional Experience

 
2017
 - 
Today
Professor and Chairperson, School of Medicine, Kitasato University
 
2010
 - 
2017
Lecturer, The University of Tokyo, CDBIM, Structural Physiology
 

Published Papers

 
Strong stimulation triggers full fusion exocytosis and very slow endocytosis of the small dense core granules in carotid glomus cells
Tse, A. Lee, A. K. Takahashi, N. Gong, A. Kasai, H. Tse, F. W.
J Neurogenetics   32(3) 267-278   Nov 2018   [Refereed]
In Vivo Volume Dynamics of Dendritic Spines in the Neocortex of Wild-Type and Fmr1 KO Mice
Ishii, K. Nagaoka, A. Kishida, Y. Okazaki, H. Yagishita, S. Ucar, H. Takahashi, N. Saito, N. Kasai, H.
eNeuro   5(5) 10.1523/eneuro.0282-18.2018   Nov 2018   [Refereed]
Munc18b increases insulin granule fusion, restoring deficient insulin secretion in type-2 diabetes human and Goto-Kakizaki rat islets with improvement in glucose homeostasis.
Qin T, Liang T, Zhu D, Kang Y, Xie L, Dolai S, Sugita S, Takahashi N, Ostenson CG, Banks K, Gaisano HY.
16 262-274   2017   [Refereed]
Kunii M, Ohara-Imaizumi M, Takahashi N, Kobayashi M, Kawakami R, Kondoh Y, Shimizu T, Simizu S, Lin B, Nunomura K, Aoyagi K, Ohno M, Ohmuraya M, Sato T, Yoshimura SI, Sato K, Harada R, Kim YJ, Osada H, Nemoto T, Kasai H, Kitamura T, Nagamatsu S, Harada A.
J Cell Biology   215(1) 121-138   2016   [Refereed]
Noguchi J, Hayama T, Watanabe S, Ucar H, Yagishita S, Takahashi N, Kasai H.
Sci Rep   6 32897   2016   [Refereed]
Komori N, Jakkampudi S, Motoishi R, Abe M, Kamada K, Furukawa K, Katan C, Sawada W, Takahashi N, Kasai H, Xue B, Kobayashi T.
Chem Commun (Camb).   52(2) 331-334   2016   [Refereed]
Takahashi N, Sawada W, Noguchi J, Watanabe S, Ucar H, Hayashi-Takagi A, Yagishita S, Ohno M, Tokumaru H, Kasai H.
Nature Communications   6 8531   Oct 2015   [Refereed]
Takahashi N.
Biol Pharm Bull   38(5) 656-662   2015   [Refereed][Invited]
Hayama T, Noguchi J, Watanabe S, Takahashi N, Hayashi-Takagi A, Ellis-Davies GC, Matsuzaki M, Kasai H.
Nat Neurosci.   16(10) 1409-1416   2013   [Refereed]
Lam PP, Ohno M, Dolai S, He Y, Qin T, Liang T, Zhu D, Kang Y, Liu Y, Kauppi M, Xie L, Wan WC, Bin NR, Sugita S, Olkkonen VM, Takahashi N, Kasai H, Gaisano HY.
Diabetes   62(7) 2416-2428   2013   [Refereed]
Kasai H, Takahashi N, Tokumaru H.
Physiol Rev   92(4) 1915-1964   2012   [Refereed]
Takahashi N.*, Hatakeyama H., Okado H., Noguchi J., Ohno M., Kasai H*.
Cell Metabolism   12 19-29   2010   [Refereed]
Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkarni RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T.
Cell Metabolism   12(6) 619-632   2010   [Refereed]
Hatakeyama H, Takahashi N, Kishimoto T, Nemoto T, Kasai H.
J Physiol   582 1087-1098   2007   [Refereed]
Kishimoto T, Kimura R, Liu TT, Nemoto T, Takahashi N, Kasai H.
EMBO J   25(4) 673-682   2006   [Refereed]
Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.
J Biol Chem   281(8) 5246-5257   2006   [Refereed]
Hatakeyama H, Kishimoto T, Nemoto T, Kasai H, Takahashi N*.
J Physiol   570 271-282   2006   [Refereed]
Fukui K, Yang Q, Cao Y, Takahashi N, Hatakeyama H, Wang H, Wada J, Zhang Y, Marselli L, Nammo T, Yoneda K, Onishi M, Higashiyama S, Matsuzawa Y, Gonzalez FJ, Weir GC, Kasai H, Shimomura I, Miyagawa J, Wollheim CB, Yamagata K.
Cell Metabolism   2(6) 373-384   2005   [Refereed]
Kishimoto T, Liu TT, Hatakeyama H, Nemoto T, Takahashi N, Kasai H.
J Physiol   568 905-915   2005   [Refereed]
Liu TT, Kishimoto T, Hatakeyama H, Nemoto T, Takahashi N, Kasai H.
J Physiol   568 917-929   2005   [Refereed]
Kasai K, Ohara-Imaizumi M, Takahashi N, Mizutani S, Zhao S, Kikuta T, Kasai H, Nagamatsu S, Gomi H, Izumi T.
J Clin Invest   115(2) 388-396   2005   [Refereed]
Takahashi N, Hatakeyama H, Okado H, Miwa A, Kishimoto T, Kojima T, Abe T, Kasai H.
J Cell Biology   165 255-262   2004   [Refereed]
Takahashi N, Kishimoto T, Nemoto T, Kadowaki T, Kasai H.
Science   297 1349-1352   2002   [Refereed]
Takahashi N*, Nemoto T, Kimura R, Tachikawa A, Miwa A, Okado H, Miyashita Y, Iino M, Kadowaki T, Kasai H.
Diabetes   51(S1) S25-S28   2002   [Refereed][Invited]
Noda M, Yamashita S, Takahashi N, Eto K, Shen LM, Izumi K, Daniel S, Tsubamoto Y, Nemoto T, Iino M, Kasai H, Sharp GW, Kadowaki T.
J Biol Chem   277(44) 41817-41826   2002   [Refereed]
Fast and cAMP-sensitive mode of Ca2+-dependent exocytosis in pancreatic β cells.
Kasai H., Suzuki T., Liu T.-T., Kishimoto T., Takahashi N.
Diabetes   S51 S19-S24   2002   [Refereed]
Takahashi N, Kadowaki T, Yazaki Y, Ellis-Davies GC, Miyashita Y, Kasai H.
Proc Natl Acad Sci USA   96 760-765   1999   [Refereed]
Eto K, Tsubamoto Y, Terauchi Y, Sugiyama T, Kishimoto T, Takahashi N, Yamauchi N, Kubota N, Murayama S, Aizawa T, Akanuma Y, Aizawa S, Kasai H, Yazaki Y, Kadowaki T.
Science   283(5404) 981-985   1999   [Refereed]
Takahashi N, Kadowaki T, Yazaki Y, Miyashita Y, Kasai H.
J Cell Biology   138(1) 55-64   1997   [Refereed]
Terauchi Y, Sakura H, Yasuda K, Iwamoto K, Takahashi N, Ito K, Kasai H, Suzuki H, Ueda O, Kamada N,Jishage K, Komeda K, Noda M, Kanazawa Y, Taniguchi S, Miwa I, Akanuma Y, Kodama T, Yazaki Y, Kadowaki T.
J Biol Chem   270(51) 30253-30256   1995   [Refereed]
Focal appearance of cerebellar torpedoes associated with discrete lesions in the cerebellar white matter
Takahashi N, Iwatsubo T, Nakano I, Machinami R.
Acta Neuropathologica   84(2) 153-156   1992   [Refereed]

Conference Activities & Talks

 
Configuration of SNARE proteins and calcium-dependent exocytosis.
Morimoto Y, Sawada W, Kasai H, Takahashi N
20th International Symposium on calcium binding proteins and calcium function in health and disease (CaBP2017)   23 Oct 2017   
Two-photon fluorescence lifetime imaging of primed SNARE complexes [Invited]
TAKAHASHI Noriko
The 39th Annual Meeting of the Japan Neuroscience Society, Novel mechanisms of the vesicular recycling in the presynaptic terminals   22 Jul 2016   Japan Neuroscience Society
SNARE configuration at presynaptic terminals analyzed with 2-photon excitation FLIM [Invited]
TAKAHASHI Noriko
The 38th Annual Meeting of the Japan Neuroscience Society   30 Jul 2015   
2-photon FLIM analysis of SNARE assembly in neuron and endocrine cells [Invited]
TAKAHASHI Noriko
the 92nd Annual Meeting of The Physiological Society of Japan, Forefront of exo- and endocytosis research   21 Mar 2015   

Research Grants & Projects

 
Physiology of pancreatic islet
Study of molecular mechanism of insulin exocytosis