Suzuki Shigeaki - My portal

Profile Information

Affiliation: Associate Professor, School of Medicine Department of Internal Medicine (Neurology), Keio University

Degree: 医学博士(Oct, 2001, 慶應義塾大学)

Researcher number: 50276242
J-GLOBAL ID: 200901080684394063
researchmap Member ID: 1000314960

External link: https://www.neurology.med.keio.ac.jp/staff/6-2/

Research Interests

Autoantibodies

Research Areas

Life sciences / Neurology / Autoimmunity

Research History

Jun, 2019 - Present

准教授, Keio University School of Medicine, Department of Neurology
Apr, 2007 - May, 2019

専任講師, Keio University School of Medicine
May, 1997 - Mar, 2007

Keio University School of Medicine, Department of Neurology
Apr, 2003 - Sep, 2003

New York Medical College
Jun, 1996 - Apr, 1997

慶應義塾大学伊勢慶應病院内科
Jun, 1996 - Apr, 1997

慶應義塾大学伊勢慶應病院内科
May, 1995 - May, 1996

Kawasaki Municipal Hosipital
Apr, 1993 - Apr, 1995

慶應義塾大学内科学教室入局（研修医）
Apr, 1993 - Apr, 1995

慶應義塾大学内科学教室入局（研修医）

Education

Mar, 1993 - Mar, 1993

慶應義塾大学医学部

Awards

Papers

154

Diagnostic potential of sarcoplasmic myxovirus resistance protein A expression in subsets of dermatomyositis

A. Uruha, Y. Allenbach, J. L. Charuel, L. Musset, A. Aussy, O. Boyer, K. Mariampillai, O. Landon-Cardinal, C. Rasmussen, L. Bolko …

Neuropathology and Applied Neurobiology, 45(5) 513-522, Aug, 2019
A case of anti-titin antibody positive nivolumab-related necrotizing myopathy with myasthenia gravis

Isami A, Uchiyama A, Shimaoka Y, Suzuki S, Kawachi I, Fujita N

Rinsho shinkeigaku = Clinical neurology, 59(7) 431-435, Jul 31, 2019
Concurrent positive anti-3-hydroxy-3-methylglutaryl-coenzyme a reductase antibody with reducing body myopathy: Possible double trouble.

Jantima Tanboon, Oranee Sanmaneechai, Sirirat Charuvanij, Tumtip Sangruchi, Angeles S Galindo-Feria, Ingrid E Lundberg, Yuko Ohnuki, Takashi Shiina, Shigeaki Suzuki, Ichizo Nishino

Neuromuscular disorders : NMD, 29(7) 543-548, Jul, 2019
Pembrolizumab-induced Ocular Myasthenia Gravis with Anti-titin Antibody and Necrotizing Myopathy.

Asako Onda, Shinji Miyagawa, Naoko Takahashi, Mina Gochi, Masamichi Takagi, Ichizo Nishino, Shigeaki Suzuki, Chizuko Oishi, Hiroshi Yaguchi

Internal medicine (Tokyo, Japan), 58(11) 1635-1638, Jun 1, 2019
Inflammatory myopathy associated with PD-1 inhibitors.

Morinobu Seki, Akinori Uruha, Yuko Ohnuki, Sachiko Kamada, Tomoko Noda, Asako Onda, Masayuki Ohira, Aiko Isami, Sumie Hiramatsu, Makoto Hibino …

Journal of autoimmunity, 100 105-113, Jun, 2019
Cytometric cell-based assays for anti-striational antibodies in myasthenia gravis with myositis and/or myocarditis.

Kenji Kufukihara, Yurika Watanabe, Takashi Inagaki, Koutaro Takamatsu, Shunya Nakane, Jin Nakahara, Yukio Ando, Shigeaki Suzuki

Scientific reports, 9(1) 5284-5284, Mar 27, 2019
Safety of tapering tacrolimus dose in patients with well-controlled anti-acetylcholine receptor antibody-positive myasthenia gravis

Nishida Y, Takahashi Y, Kanai T, Nose Y, Ishibashi S, Sanjo N, Uzawa A, Oda F, Ozawa Y, Kuwabara S …

European Journal of Neurology, 2019
Significance of follow-up thoracic imaging in myasthenia gravis

Murai H, Nagane Y, Suzuki S, Imai T, Motomura M, Utsugisawa K

Clinical and Experimental Neuroimmunology, 9(4) 246-250, Nov, 2018
Immune checkpoint inhibitors in the onset of myasthenia gravis with hyperCKemia.

Koutaro Takamatsu, Shunya Nakane, Shigeaki Suzuki, Takayuki Kosaka, Satoshi Fukushima, Toshihiro Kimura, Azusa Miyashita, Akihiro Mukaino, Shiori Yamakawa, Keisuke Watanabe …

Annals of clinical and translational neurology, 5(11) 1421-1427, Nov, 2018
Neuromuscular adverse events

Suzuki S

Japanese Journal of Cancer and Chemotherapy, 45(7) 1036-1040, Jul, 2018
Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial.

Sonoko Misawa, Satoshi Kuwabara, Yasunori Sato, Nobuko Yamaguchi, Kengo Nagashima, Kanako Katayama, Yukari Sekiguchi, Yuta Iwai, Hiroshi Amino, Tomoki Suichi …

The Lancet. Neurology, 17(6) 519-529, Jun, 2018
Immune checkpoint inhibitors and neuromuscular adverse events

Suzuki S

Brain and Nerve, 70(4) 461-466, Apr, 2018
Mitophagy in three cases of immune-mediated necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies: ultrastructural and immunohistochemical studies.

Shiro Matsubara, Kota Bokuda, Yuri Asano, Ryo Morishima, Keizo Sugaya, Kazuhito Miyamoto, Reiji Koide, Takashi Komori, Shigeaki Suzuki, Ichizo Nishino

Neuromuscular disorders : NMD, 28(3) 283-288, Mar, 2018
The first report of a japanese case of seipinopathy with a BSCL2 N88S mutation

Kazushi Minami, Shinichi Takahashi, Yoshihiro Nihei, Koichi Oki, Shigeaki Suzuki, Daisuke Ito, Hiroshi Takashima, Norihiro Suzuki

Internal Medicine, 57(4) 613-615, 2018
Successful treatment with nivolumab and concomitant radiation therapy under control of autoimmune diseases

Ota A, Aoyama R, Tanemura A, Kotobuki Y, Katayama I, Kakuta K, Tsujimoto K, Tanaka T, Suzuki S

Skin Research, 17(2) 62-69, 2018
Rationale for the clinical guidelines for myasthenia gravis in Japan

Hiroyuki Murai, Kimiaki Utsugisawa, Yuriko Nagane, Shigeaki Suzuki, Tomihiro Imai, Masakatsu Motomura

Annals of the New York Academy of Sciences, 1413(1) 35-40, 2018
New onset of myasthenia gravis after intravesical Bacillus Calmette-Guerin A case report and literature review

Tsubasa Takizawa, Marenori Kojima, Shigeaki Suzuki, Takashi Osada, Satoshi Kitagawa, Jin Nakahara, Shinichi Takahashi, Norihiro Suzuki

MEDICINE, 96(46), Nov, 2017
A clinical predictive score for postoperative myasthenic crisis

Tetsuya Kanai, Akiyuki Uzawa, Yasunori Sato, Shigeaki Suzuki, Naoki Kawaguchi, Keiichi Himuro, Fumiko Oda, Yukiko Ozawa, Jin Nakahara, Norihiro Suzuki …

ANNALS OF NEUROLOGY, 82(5) 841-849, Nov, 2017
Hyponatremia associated with human herpesvirus-6 (HHV-6) encephalitis after allogeneic hematopoietic stem cell transplantation: A presentation different from HHV-6 myelitis

Koichi Murakami, Sumiko Kohashi, Masatoshi Sakurai, Jun Kato, Takaaki Toyama, Yuya Koda, Yusuke Yamane, Risa Hashida, Ryohei Abe, Rie Yamazaki …

INTERNATIONAL JOURNAL OF HEMATOLOGY, 106(3) 436-440, Sep, 2017
Nivolumab-related myasthenia gravis with myositis and myocarditis in Japan

Shigeaki Suzuki, Nobuhisa Ishikawa, Fumie Konoeda, Nobuhiko Seki, Satoshi Fukushima, Kikuko Takahashi, Hisashi Uhara, Yoshikazu Hasegawa, Shinichiro Inomata, Yasushi Otani …

NEUROLOGY, 89(11) 1127-1134, Sep, 2017

Misc.

Absence of sarcoplasmic myxovirus resistance protein A (MxA) expression in antisynthetase syndrome in a cohort of 194 cases

M. Inoue, J. Tanboon, M. Okubo, K. Theerawat, Y. Saito, M. Ogasawara, L. A. Indrawati, A. Uruha, N. Okiyama, M. Fujimoto …

Neuropathology and Applied Neurobiology, 45(5) 523-524, Aug, 2019
Eculizumab improved weakness and taste disorder in thymoma-associated generalized myasthenia gravis with anti-striational antibodies: A case report

Amano E, Otsu S, Suzuki S, Machida A

eNeurologicalSci, 14 72-73, Mar, 2019
Alternative to steroid therapy for myasthenia gravis and myositis occurring as immune-related adverse events

Kamada S, Hanazono A, Sanpei Y, Inoue T, Suzuki S, Sugawara M, Iijima K

Clinical and Experimental Neuroimmunology, 10(3) 190-191, 2019
New Criteria Needed for Antisynthetase Syndrome-Reply.

Shigeaki Suzuki, Akinori Uruha, Ichizo Nishino

JAMA neurology, 75(2) 259-260, Feb 1, 2018
Perifascicular necrosis in anti-synthetase syndrome beyond anti-Jo-1

Uruha Akinori, Suzuki Shigeaki, Suzuki Norihiro, Nishino Ichizo

BRAIN, 139, Sep, 2016

Presentations

脳虚血・再灌流時のサイクリックAMP応答因子結合蛋白(CREB)リン酸化と細胞保護

Tanakakoutarou, Suzukishigeaki, Denpoutomohisa, Kosakaiarifumi

第80回日本生理学会大会, Mar, 2003 Invited
オリゴデンドロサイトおよびその前駆細胞の脳虚血反応

Tanaka Koutarou, Nagata Eiichirou, Suzuki Shigeaki, Denpou Tomohisa, Kosakai Arifumi

第14回日本脳循環代謝学会総会, Nov, 2002 Invited
実験的脳虚血後のIL-6 cytokine family共有受容体GP130の細胞局在

Suzukishigeaki, Tanakakoutarou, Nogawashigeru, Denpousomohisa, Kosakaiarifumi, Fukuuchiyasuo

第14回日本脳循環代謝学会総会, Nov, 2002
Activation and proleferation of oligodendrocyte progenitor cells after brain ischemia

Tanaka Kotaro, Nogawa Shigeru, Ito Daisuke, Suzuki Shigeaki, Dembo Tomohisa, Kosakai Arifumi, Fukuuchi Yasuo

Joint international symposium on molecular mechanism and epochal therapeutics dor ischemic stroke and dementia, Oct, 2002 Invited
COX-2 expression in brains of patients with familial Alzheimer's disease

Nogawa Shigeru, Takao Motoki, Suzuki Shigeaki, Tanaka Kortaro, Koto Atsuo, Fukuuchi Yasuo, Hayakawa Isao

International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke Dementia, Oct, 2002
オリゴデンドロサイト前期細胞の局所脳虚血・再灌流時の活性化・増殖反応

Tanaka koutarou, Nogawa shigeru, Suzuki shigeaki, Denbou tomohisa, Kosakai arifumi

第17回神経組織の成長・再生・移植研究会, Jun, 2002
：赤芽球癆(PRCA)を合併した重症筋無力症(MG)の臨床特徴

Suzuki Shigeaki, Kuwana Masataka, Tanaka Koutarou, Nogawa Shigeru, Kotou Atsuo, Fukuuchi Yasuo

第43回日本神経学会総会, May, 2002
高CPK血症のみを認めたMcArdle病の兄弟例―初期の筋電図所見と筋病理の対比―

Suzuki Shigeaki, Nogawa Shigeru, Tanaka Koutarou, Amano Takahiro, Fukuuchi Yasuo

第160回日本神経学会関東地方会, Apr, 2002
高CPK血症のみを呈したMcArdle病の兄弟例：初期の筋電図所見と筋病理の対比

Suzuki Shigeaki, Nogawa Shigeru, Tanaka Koutarou, Amano Takahiro, Fukuuchi Yasuo

第160回日本神経学会関東地方会, Mar, 2002
重症筋無力症におけるアセチルコリン受容体a鎖P3Aエクソン領域に対する自己反応性T細胞の解析

Suzuki Shigeaki, Kuwana Masataka, Yasuoka Hidekata, Tanaka Koutarou, Kawakami Yutaka, Fukuuchi Yasuo

第12回日本神経免疫学会, Feb, 2002
重症筋無力症におけるアセチルコリン受容体α鎖P3Aエクソン領域に対する自己反応性T細胞の検討。

Suzuki Shigeaki, Kuwana Masataka, Yasuoka Hidekata, Tanaka Koutarou, Kawakami Yutaka, Fukuuchi Yasuo

第14回日本神経免疫学会学術集会, Jan, 2002
赤芽球癆（PRCA）を合併した重症筋無力症（MG）の臨床特徴

Suzuki Shigeaki, Kuwana Masataka, Tanaka Koutarou, Nogawa Shigeru, Kotou Atsuo, Fukuuchi Yasuo

第43回日本神経学会総会, 2002
赤芽球癆（PRCA）を合併した重症筋無力症（MG）の臨床特徴

Suzuki Shigeaki, Kuwana Masataka, Tanaka Koutarou, Nogawa Shigeru, Kotou Atsuo, Fukuuchi Yasuo

第43回日本神経学会総会, 2002
オリゴデンドロサイト前駆細胞の局所脳虚血・再灌流時における活性化

Tanaka Koutarou, Fukuuchi Yasuo, Nogawa Shigeru, Itou Daisuke, Suzuki Shigeaki, Denbou Tomohisa, Kosakai Arifumi

第13回日本脳循環代謝学会総会, Oct, 2001
Trousseau症候群の剖検例における大脳および卵巣組織でのinterleukin-6発現

Suzuki Shigeaki, Tanaka Koutarou, Nogawa Shigeru, Fukuuchi Yasuo

第13回日本脳循環代謝学会総会, Oct, 2001
Persistent phosphorylation of cyclic AMP response element binding protein (CREB) is closely associated neuronal survial post-iscehmic recirculation in the rat brain

Tanaka Kortaro, Fukuuchi Yasuo, Nogawa Shigeru, Ito Daisuke, Suzuki Shigeaki, Dembo Tomohisa, Kosakai Arifumi

International Symposium on Cerebral Blood Flow, Metabolsim and Function (20th ; 2001 ; Taipei), Jun, 2001
Enhanced expression of Iba1, ionized calsium-binding adaptor molecule 1, after transient focal sichemia in rat brain

Ito Daisuke, Tanaka Kortaro, Suzuki Shigeaki, Dembo Tomohisa, Fukuuchi Yasuo

International Symposium on Cerebral Blood Flow, Metabolism and Fucntion (20th ; 2001 ; Taipei), Jun, 2001
Expression of interleukin-6 and leukemia inhibitory factor after cerebral ischemia

Suzuki Shigeaki, Tanaka Kortaro, Nogawa Shigeru, Dembo Tomohisa, Kosakai Arifumi, Fukuuuchi Yasuo

International Symposium on Cerebral Blood Flow, Metabolism and Function (20th ; 2001 ; Taipei), Jun, 2001
高齢発症の重症筋無力症における治療法の選択に関する検討

Suzuki Shigeaki, Sasaki Takahiro, Nogawa Shigeru, Hamada Junichi, Tanaka Koutarou, Tanahashi Norio, Amano Takahiro, Kotou Atsuo, Fukuuchi Yasuo

第19回日本神経治療学会総会, Jun, 2001
高齢発症の重症筋無力症における治療法の選択に関する検討

Suzuki Shigeaki, Sasaki Takahiro, Nogawa Shigeru, Hamada Junichi, Tanaka Koutarou, Tanahashi Norio, Amano Takahiro, Kotou Atsuo, Fukuuchi Yasuo

第19回日本神経治療学会総会, Jun, 2001

Teaching Experience

Apr, 2024 - Mar, 2025

LECTURE SERIES, INTERNAL MEDICINE (NEUROLOGY) (Keio University)
Apr, 2023 - Mar, 2024

LECTURE SERIES, INTERNAL MEDICINE (NEUROLOGY) (Keio University)
Apr, 2023 - Mar, 2024

LECTURE SERIES, INTERNAL MEDICINE (Keio University)
Apr, 2023 - Mar, 2024

IMMUNOLOGY (Keio University)
Apr, 2022 - Mar, 2023

LECTURE SERIES, INTERNAL MEDICINE (NEUROLOGY) (Keio University)
Apr, 2022 - Mar, 2023

LECTURE SERIES, INTERNAL MEDICINE (Keio University)
Apr, 2022 - Mar, 2023

IMMUNOLOGY (Keio University)
Apr, 2021 - Mar, 2022

LECTURE SERIES, INTERNAL MEDICINE (NEUROLOGY) (Keio University)
Apr, 2021 - Mar, 2022

LECTURE SERIES, INTERNAL MEDICINE (Keio University)
Apr, 2021 - Mar, 2022

IMMUNOLOGY (Keio University)
Apr, 2020 - Mar, 2021

LECTURE SERIES, INTERNAL MEDICINE (NEUROLOGY) (Keio University)
Apr, 2020 - Mar, 2021

LECTURE SERIES, INTERNAL MEDICINE (Keio University)
Apr, 2020 - Mar, 2021

IMMUNOLOGY (Keio University)
Apr, 2019 - Mar, 2020

LECTURE SERIES, INTERNAL MEDICINE (NEUROLOGY) (Keio University)
Apr, 2019 - Mar, 2020

LECTURE SERIES, INTERNAL MEDICINE (Keio University)
Apr, 2019 - Mar, 2020

IMMUNOLOGY (Keio University)
Apr, 2015 - Mar, 2016

神経疾患各論（多発性硬化症・免疫介在性脳炎） (Keio University)
神経疾患各論（多発性硬化症・免疫介在性脳炎） (慶應義塾)

Research Projects

抗横紋筋抗体の病因論的自己抗体としての意義とPD-1ミオパチーの疾患概念の確立

Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), MEXT,JSPS, Apr, 2020 - Mar, 2025

鈴木重明
壊死性ミオパチーに関連する自己抗体の病態機序の解明と臨床応用に向けて

Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), MEXT,JSPS, Apr, 2017 - Mar, 2020

鈴木重明
Clinical and histological features of inflammatory myopathies mediated by autoantibodies

Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), MEXT,JSPS, Apr, 2014 - Mar, 2017

鈴木重明
横紋筋細胞を用いた免疫沈降法による自己抗体検索の臨床応用に向けて

科学研究費（基盤研究C）, 文部科学省, Apr, 2011 - Mar, 2014

鈴木重明
慢性期脳虚血の病態におけるStat3リン酸化の意義

科学研究費（基盤研究C）, 文部科学省, Apr, 2008 - Mar, 2011
重症筋無力症患者における電位依存性Kチャネル(Kv1.4)に対する自己抗体の意義

科学研究費（若手研究B）, 文部科学省, Apr, 2006 - Mar, 2008

鈴木重明
重症筋無力症患者における横紋筋特異的な新規自己抗体の同定

科学研究費（若手研究B）, 文部科学省, Apr, 2004 - Mar, 2006

鈴木重明
脳虚血後の髄鞘修復におけるグリア系細胞の動態とサイトカインの発現

科学研究費（若手研究B）, 文部科学省, Apr, 2002 - Mar, 2004
日本人重症筋無力症の病因的自己反応性T細胞に認識されるT細胞エピトープの解析

科学研究費（奨励研究A）, 文部科学省, Apr, 2000 - Mar, 2002

鈴木重明