橋本祐一 (Yuuichi Hashimoto) - マイポータル

基本情報

学位: 医学(順天堂大学)

J-GLOBAL ID: 200901086021679631
researchmap会員ID: 1000314964

研究分野

ライフサイエンス / 薬理学 /

学歴

- 1990年

順天堂大学, 体育学研究科
- 1988年

鹿屋体育大学

論文

CLSPCOL rescues Alzheimer's disease mouse models.

Shinya Kusakari, Mikiro Nawa, Yuichi Hashimoto, Masaaki Matsuoka

Translational neuroscience 13(1) 11-19 2022年1月1日
Improvement in Aqueous Solubility in Small Molecule Drug Discovery Programs by Disruption of Molecular Planarity and Symmetry

Minoru Ishikawa, Yuichi Hashimoto

JOURNAL OF MEDICINAL CHEMISTRY 54(6) 1539-1554 2011年3月査読有り
Expression of N19S-SOD1, an SOD1 mutant found in sporadic amyotrophic lateral sclerosis patients, induces low-grade motoneuronal toxicity

Yuji Obata, Takako Niikura, Kohsuke Kanekura, Yuichi Hashimoto, Masaoki Kawasumi, Yoshiko Kita, Sadakazu Aiso, Masaaki Matsuoka, Ikuo Nishimoto

Journal of Neuroscience Research 81(5) 720-729 2005年9月1日査読有り
Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein-3 regulates cell survival and apoptosis

M Ikonen, BR Liu, Y Hashimoto, LQ Ma, KW Lee, T Niikura, Nishimoto, I, P Cohen

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(22) 13042-13047 2003年10月査読有り
The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.

Yuichi Hashimoto, Takako Niikura, Tomohiro Chiba, Emi Tsukamoto, Hisae Kadowaki, Hideki Nishitoh, Yohichi Yamagishi, Miho Ishizaka, Marina Yamada, Mikiro Nawa …

The Journal of pharmacology and experimental therapeutics 306(3) 889-902 2003年9月
Characterization of the toxic mechanism triggered by Alzheimer's amyloid-β peptides via p75 neurotrophin receptor in neuronal hybrid cells

Emi Tsukamoto, Yuichi Hashimoto, Kohsuke Kanekura, Takako Niikura, Sadakazu Aiso, Ikuo Nishimoto

Journal of Neuroscience Research 73(5) 627-636 2003年9月1日査読有り
Alzheimer病における神経細胞死の分子メカニズム (Alzheimer病の分子メカニズム)

金蔵孝介, 新倉貴子, 橋本祐一

医学のあゆみ 206(3) 210-217 2003年7月19日
Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: Functional potentiation by isomerization and dimerization

Kenzo Terashita, Yuichi Hashimoto, Takako Niikura, Hirohisa Tajima, Yohichi Yamagishi, Miho Ishizaka, Masaoki Kawasumi, Tomohiro Chiba, Kohsuke Kanekura, Marina Yamada …

Journal of Neurochemistry 85(6) 1521-1538 2003年6月査読有り
Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults

Y Yamagishi, Y Hashimoto, T Niikura, Nishimoto, I

PEPTIDES 24(4) 585-595 2003年4月査読有り
Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death

Yuichi Hashimoto, Osahiko Tsuji, Takako Niikura, Yohichi Yamagishi, Miho Ishizaka, Masaoki Kawasumi, Tomohiro Chiba, Kohsuke Kanekura, Marina Yamada, Emi Tsukamoto …

Journal of Neurochemistry 84(4) 864-877 2003年2月
Death and survival of neuronal cells exposed to Alzheimer's insults

T Niikura, Y Hashimoto, H Tajima, Nishimoto, I

JOURNAL OF NEUROSCIENCE RESEARCH 70(3) 380-391 2002年11月
Molecular mechanisms for neuronal cell death by Alzheimer's amyloid precursor protein-relevant insults

M Kawasumi, Y Hashimoto, T Chiba, K Kanekura, Y Yamagishi, M Ishizaka, H Tajima, T Niikura, Nishimoto, I

NEUROSIGNALS 11(5) 236-250 2002年9月
Neurotoxic mechanisms by Alzheimer's disease-linked N141I mutant presenilin 2

Y Hashimoto, T Niikura, Y Ito, Y Kita, K Terashita, Nishimoto, I

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 300(3) 736-745 2002年3月
Neurotoxic mechanisms triggered by Alzheimer's disease-linked mutant M146L presenilin 1: involvement of NO synthase via a novel pertussis toxin target

Y Hashimoto, Y Ito, E Arakawa, Y Kita, K Terashita, T Niikura, Nishimoto, I

JOURNAL OF NEUROCHEMISTRY 80(3) 426-437 2002年2月
Detailed characterization of neuroprotection by a rescue factor Humanin against various Alzheimer's disease-relevant insults

Y Hashimoto, T Niikura, Y Ito, H Sudo, M Hata, E Arakawa, Y Abe, Y Kita, Nishimoto, I

JOURNAL OF NEUROSCIENCE 21(23) 9235-9245 2001年12月
A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

HASHIMOTO Y, NIIKURA T, TAJIMA H, YASUKAWA T, SUDO H, SOBUE G, KOIDE T, KUROKAWA K, NISHIMOTO I

Proceedings of the National Academy of the Sciences of the United States of America 98(11) 6336-6341 2001年5月
Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein

Y Hashimoto, Y Ito, T Niikura, Z Shao, M Hata, F Oyama, Nishimoto, I

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 283(2) 460-468 2001年5月
ヒューマニン─各種Alzheimer病関連刺激が誘導する神経細胞死を抑制する新規の短鎖ペプチド

川澄正興, 橋本祐一, 新倉貴子

医学のあゆみ 199(7) 523-526 2001年
臨床応用に向けたアルツハイマ－病研究

実験医学 19 2265-2270 2001年
Neuronal cell apoptosis by a receptor-binding domain peptide of ApoE4, not through low-density lipoprotein receptor-related protein

Akari Hagiwara, Yuichi Hashimoto, Takako Niikura, Yuko Ito, Kenzo Terashita, Yoshiko Kita, Ikuo Nishimoto, Kazuo Umezawa

Biochemical and Biophysical Research Communications 278(3) 633-639 2000年11月30日

もっとみる

主要なMISC

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and A beta (vol 98, pg 6336, 2001)

Y Hashimoto, T Niikura, H Tajima, T Yasukawa, H Sudo, Y Ito, Y Kita, M Kawasumi, K Kouyama, M Doyu …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(22) 12854-12854 2001年10月

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橋本祐一

基本情報

研究分野

学歴

論文

主要なMISC

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