1999年11月
Interaction among the subunits of golgi membrane mannosyltransferase complexes of the yeast Saccharomyces cerevisiae
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- ,
- ,
- 巻
- 63
- 号
- 11
- 開始ページ
- 1970
- 終了ページ
- 1976
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1271/bbb.63.1970
- 出版者・発行元
- TAYLOR & FRANCIS LTD
Saccharomyces cerevisiae Mnn9 protein is a type II Golgi membrane protein which concerns in protein mannosylation. When solubilized by Triton X-100, it was recovered in two distinct complexes both baring mannosyltransferase activity; one with Van1 protein (V-complex) and the other with Anp1, Hocl, Mnn10, and Mnn11 proteins (A-complex). Characterization of the null mutants suggested that A-complex is also concerned in protein O-glycosylation. A-complex was more resistant than V-complex to dissociating conditions. Interaction between the lumenal domains of Van1 and Mnn9 was detected by a two-hybrid experiment. The anchor domain of Mnn9 protein could be replaced with other membrane anchors without losing the ability to form complexes similar to V- and A-complexes. Thus the lumenal domains are important to assemble these distinct complexes.
- リンク情報
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- DOI
- https://doi.org/10.1271/bbb.63.1970
- CiNii Articles
- http://ci.nii.ac.jp/naid/110002679397
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/10635561
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000084016700018&DestApp=WOS_CPL
- ID情報
-
- DOI : 10.1271/bbb.63.1970
- ISSN : 0916-8451
- eISSN : 1347-6947
- CiNii Articles ID : 110002679397
- PubMed ID : 10635561
- Web of Science ID : WOS:000084016700018