MATSUOKA Isao

J-GLOBAL         Last updated: Nov 16, 2018 at 18:55
 
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Name
MATSUOKA Isao
Nickname
130m
Affiliation
Takasaki University of Health and Welfare
Research funding number
10145633

Research Areas

 
 

Academic & Professional Experience

 
Apr 2006
 - 
Today
Professor, Faculty of Pharmacy, Takasaki University of Health and Welfare
 
Aug 1999
 - 
Mar 2006
Associate professor, School of Medicine, Fukusima Medical University
 
Apr 1981
 - 
Aug 1999
Research Assistant, School of Medicine, Fukusima Medical University
 

Education

 
 
 - 
1981
Faculty of Pharmaceutical Science, Hokkaido University
 

Published Papers

 
Yuji Odagaki, Masakazu Kinoshita, Toshio Ota, J. Javier Meana, J. Javier Meana, Luis F. Callado, Luis F. Callado, Isao Matsuoka, Jesús A. García-Sevilla
Purinergic Signalling   14 177-190   Jun 2018
© 2018, Springer Science+Business Media B.V., part of Springer Nature. Adenosine signaling plays a complex role in multiple physiological processes in the brain, and its dysfunction has been implicated in pathophysiology of neuropsychiatric diseas...
Kazuki Yoshida, Masaaki Ito, Yui Hoshino, Isao Matsuoka
Biochemical and Biophysical Research Communications   493 1587-1593   Dec 2017
© 2017 Elsevier Inc. Mast cells express many different purinergic receptors, including ionotropic P2X4 and P2X7, which recognize the accumulation of extracellular ATP released from activated and/or damaged cells. This results in the stimulation of...
Masaaki Ito, Shin ichiro Egashira, Kazuki Yoshida, Tomoko Mineno, Kazuo Kumagai, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Michio Ui, Isao Matsuoka
Life Sciences   180 137-142   Jul 2017
© 2017 Aims The P2Y6nucleotide receptor is widely involved in inflammatory responses, and is a promising molecular target for the treatment of inflammatory diseases. Although several P2Y6receptor antagonists have been developed and evaluated thus ...
Kazuki Yoshida, Masaaki Ito, Isao Matsuoka
International Immunopharmacology   43 99-107   Feb 2017
© 2016 Elsevier B.V. Mast cells (MCs) play a critical role in allergic inflammation. Although purinergic signalling is implicated in the regulation of various immune responses, its role in MC function is not fully understood. In this study, we inv...
Kazuki Yoshida, Masaaki Ito, Isao Matsuoka
European Journal of Pharmacology   767 41-51   Nov 2015
© 2015 Elsevier B.V. Activation of the P2X7 receptor by extracellular ATP is associated with various immune responses including allergic inflammation. Anti-allergic agents, such as H1-antihistamines, are known to inhibit the effects of different c...

Misc

 
P2Z/P2X7 receptor
KIMURA Junko, KAIHO Hiromi, MATSUOKA Isao
2 241-246   1999
Regulation of adenylyl cyclase gene expression by nicotine
The Autonomic nerve system   37 370-375

Research Grants & Projects

 
Role of extracellular nucleotide metabolism in regulation of physiological response
Molecular Pharmacology of ATP receptors