MISC

2001年8月

Post-ischemic hypothermia blocks caspase-3 activation in the newborn rat brain after hypoxia-ischemia

BRAIN RESEARCH
  • H Fukuda
  • ,
  • T Tomimatsu
  • ,
  • N Watanabe
  • ,
  • JW Mu
  • ,
  • M Kohzuki
  • ,
  • M Endo
  • ,
  • E Fujii
  • ,
  • T Kanzaki
  • ,
  • Y Murata

910
1-2
開始ページ
187
終了ページ
191
記述言語
英語
掲載種別
DOI
10.1016/S0006-8993(01)02659-2
出版者・発行元
ELSEVIER SCIENCE BV

The effects of hypothermia on caspase-3 activation were investigated in the newborn rat brain after hypoxia-ischemia (HI). Intense caspase-3 activation was observed in the control brains after HI, but this activation was significantly reduced by postischemic hypothermia. These findings suggest that the inhibition of caspase-3 activation array be an interventional point underlying the neuroprotective effect of hypothermia in neonates. (C) 2001 Elsevier Science B.V. All rights reserved.

Web of Science ® 被引用回数 : 56

リンク情報
DOI
https://doi.org/10.1016/S0006-8993(01)02659-2
CiNii Articles
http://ci.nii.ac.jp/naid/10017132539
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/11489270
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000170683300023&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/S0006-8993(01)02659-2
  • ISSN : 0006-8993
  • CiNii Articles ID : 10017132539
  • PubMed ID : 11489270
  • Web of Science ID : WOS:000170683300023

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