山田源 (Gen Yamada) - マイポータル

基本情報

所属: 和歌山医大　WMU 形成外科　（先端医学研）特別研究員 (名誉教授)

J-GLOBAL ID: 200901065185955160
researchmap会員ID: 1000320110

研究分野

経歴

2022年4月 - 現在

和歌山医大形成外科特別研究員 (名誉教授)
2011年7月 - 2022年3月

和歌山医大 WMU 先端研教授

委員歴

SREP editorial member
2004年 - 2005年

日本学術振興会特別研究員など審査会専門委員（2004-2005）
2007年

- Society for Developmental Biology
2007年

- Congenital Anomalies
2007年

日本発生生物学会合同年会実行委員

論文

The role of p63 in embryonic external genitalia outgrowth in mice.

Kosei Tanaka, Daisuke Matsumaru, Kentaro Suzuki, Gen Yamada, Shinichi Miyagawa

Development, growth & differentiation 2023年1月21日
Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice.

Mellissa C Alcantara, Kentaro Suzuki, Alvin R Acebedo, Daiki Kajioka, Satoshi Hirohata, Tsuneyasu Kaisho, Yu Hatano, Kazuo Yamagata, Satoru Takahashi, Gen Yamada

iScience 25(12) 105609-105609 2022年12月22日
Exposure to the organophosphate pesticide fenitrothion directly induced defects in mouse embryonic external genitalia.

Alvin R Acebedo, Mellissa C Alcantara, Tsuyoshi Nakanishi, Takehiko Ogawa, Gen Yamada, Kentaro Suzuki

Toxicological sciences : an official journal of the Society of Toxicology 2022年8月11日
Androgen/Wnt/β-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum.

Mizuki Kajimoto, Kentaro Suzuki, Yuko Ueda, Kota Fujimoto, Toru Takeo, Naomi Nakagata, Taiju Hyuga, Kyoichi Isono, Gen Yamada

Congenital anomalies 62(3) 123-133 2022年5月
Development of Surgical and Visualization Procedures to Analyze Vasculatures by Mouse Tail Edema Model.

Shinji Kumegawa, Gen Yamada, Daiki Hashimoto, Tsuyoshi Hirashima, Mizuki Kajimoto, Kyoichi Isono, Kota Fujimoto, Kentaro Suzuki, Kazuhisa Uemura, Masatsugu Ema, Shinichi Asamura

Biological procedures online 23(1) 21-21 2021年11月11日
Stage-dependent function of Wnt5a during male external genitalia development.

Mellissa C Alcantara, Kentaro Suzuki, Alvin R Acebedo, Yuki Sakamoto, Michiru Nishita, Yasuhiro Minami, Akira Kikuchi, Gen Yamada

Congenital anomalies 2021年7月13日
Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes

Daiki Kajioka, Kentaro Suzuki, Shoko Matsushita, Shinjiro Hino, Tetsuya Sato, Shuji Takada, Kyoichi Isono, Toru Takeo, Mizuki Kajimoto, Naomi Nakagata, Mitsuyoshi Nakao, Mikita Suyama, Tony DeFalco, Shinichi Miyagawa, Gen Yamada

Proceedings of the National Academy of Sciences 118(23) e2024067118-e2024067118 2021年6月8日
Radiation inducible MafB gene is required for thymic regeneration.

Daiki Hashimoto, Jose Gabriel R Colet, Aki Murashima, Kota Fujimoto, Yuko Ueda, Kentaro Suzuki, Taiju Hyuga, Hiroaki Hemmi, Tsuneyasu Kaisho, Satoru Takahashi, Yousuke Takahama, Gen Yamada

Scientific reports 11(1) 10439-10439 2021年5月17日
3D reconstruction and histopathological analyses on murine corporal body.

Daiki Hashimoto, Mizuki Kajimoto, Yuko Ueda, Taiju Hyuga, Kota Fujimoto, Saaya Inoue, Kentaro Suzuki, Tomoya Kataoka, Kazunori Kimura, Gen Yamada

Reproductive medicine and biology 20(2) 199-207 2021年4月査読有り
New Insights into Development of Female Reproductive Tract—Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development

Ryuma Haraguchi, Gen Yamada, Aki Murashima, Daisuke Matsumaru, Riko Kitazawa, Sohei Kitazawa

International Journal of Molecular Sciences 22(3) 1211-1211 2021年1月26日
Evaluation of surgical procedures of mouse urethra by visualization and the formation of fistula

Taiju Hyuga, Daiki Hashimoto, Daisuke Matsumaru, Shinji Kumegawa, Shinichi Asamura, Kentaro Suzuki, Kei-ichi Katayama, Shigeru Nakamura, Hideo Nakai, Gen Yamada

Scientific Reports 10(1) 18251-18251 2020年12月査読有り
総排泄腔分割の三次元イメージング解析発生毒性メカニズムの解明に向けて

松丸大輔, 村嶋亜紀, 宮川信一, 原田理代, 山田源, 中西剛

日本薬学会年会要旨集 140年会 26J-pm19 2020年3月
総排泄腔分割の三次元イメージング解析発生毒性メカニズムの解明に向けて

松丸大輔, 村嶋亜紀, 宮川信一, 原田理代, 山田源, 中西剛

日本薬学会年会要旨集 140年会 26J-pm19 2020年3月
Hedgehog Signaling for Urogenital Organogenesis and Prostate Cancer: An Implication for the Epithelial–Mesenchyme Interaction (EMI)

Taiju Hyuga, Mellissa Alcantara, Daiki Kajioka, Ryuma Haraguchi, Kentaro Suzuki, Shinichi Miyagawa, Yoshiyuki Kojima, Yutaro Hayashi, Gen Yamada

International Journal of Molecular Sciences 21(1) 58 2019年12月20日査読有り
Regulatory roles of epithelial-mesenchymal interaction (EMI) during early and androgen dependent external genitalia development.

Hyuga T, Suzuki K, Acebedo AR, Hashimoto D, Kajimoto M, Miyagawa S, Enmi J, Yoshioka Y, Yamada G

Differentiation 110 29-35 2019年11月査読有り
外生殖器亀頭海綿体における性差構築過程の解析

根本みずき, Ipulan Lerrie Ann, 松丸大輔, 橋本大輝, 日向泰樹, 鈴木堅太郎, 山田源

和歌山医学 70(2) 54-60 2019年6月
Developmental mutant mouse models for external genitalia formation.

Daiki Hashimoto, Taiju Hyuga, Alvin R Acebedo, Mellissa C Alcantara, Kentaro Suzuki, Gen Yamada

Congenital anomalies 59(3) 74-80 2019年5月
Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice

Alvin R. Acebedo, Kentaro Suzuki, Shinjiro Hino, Mellissa C. Alcantara, Yuki Sato, Hisashi Haga, Ken-ichi Matsumoto, Mitsuyoshi Nakao, Kenji Shimamura, Toru Takeo, Naomi Nakagata, Shinichi Miyagawa, Ryuichi Nishinakamura, Robert S. Adelstein, Gen Yamada

Communications Biology 2 95 2019年3月査読有り
Bmp4 is an essential growth factor for the initiation of genital tubercle (GT) outgrowth

Kajioka D, Suzuki K, Nakada S, Matsushita S, Miyagawa S, Takeo T, Nakagata N, Yamada G

Congenital Anomalies 2019年2月査読有り
The Role of Fgf Signaling on Epithelial Cell Differentiation in Mouse Vagina

YU HIRANO, KENTARO SUZUKI, TAISEN IGUCHI, GEN YAMADA, SHINICHI MIYAGAWA

In Vivo 33(5) 1499-1505 2019年

もっとみる

MISC

X線誘導性胸腺退縮における組織学的解析加齢性胸腺退縮との比較

橋本大輝, Colet Jose G, 村嶋亜紀, 山田源

和歌山医学 69(1) 24-28 2018年3月
The roles of androgen and growth factor signaling in Wolffian duct development

Aki Murashima, Gen Yamada

MECHANISMS OF DEVELOPMENT 145 S150-S150 2017年7月
雄性生殖管-ウォルフ管-に着目した雌性生殖器の発生機序についての考察

原口竜摩, 北澤理子, 松丸大輔, 山田源, 北澤荘平

日本病理学会会誌 102(1) 436-436 2013年4月
アンドロゲンシグナルの性差構築機構器官形成における性差発現の新次元

村嶋亜紀, 宮川信一, 荻野由紀子, 中潟直己, 山田源

細胞工学 30(8) 856-862 2011年7月
Essential functions of androgen signaling emerged through the developmental analysis of vertebrate sex characteristics

Yukiko Ogino, Shinichi Miyagawa, Hironori Katoh, Gail S. Prins, Taisen Iguchi, Gen Yamada

EVOLUTION & DEVELOPMENT 13(3) 315-325 2011年5月
New horizons at the caudal embryos: coordinated urogenital/reproductive organ formation by growth factor signaling

Kentaro Suzuki, Aris Economides, Motoko Yanagita, Daniel Graf, Gen Yamada

CURRENT OPINION IN GENETICS & DEVELOPMENT 19(5) 491-496 2009年10月
Genetic interactions of the Androgen and Wnt/β-catenin Pathways for the Masculinization of External Genitalia.

Miyagawa,S, Satoh,Y, Haraguchi,R, Suzuki,K, Iguchi,T, Taketo,M.M, Nakagata,N, Matsumoto,T, Takeyama,KI, Kato,S. a, Yamada,G

Molecular Endocrinology 23(6) 871-880 2009年6月
Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling.

Suzuki,K, Yamaguchi,Y, Villacorte,M, Mihara,M, Akiyama,M, Shimizu,H, Taketo,M.M, Nakagata,N, Tsukiyama,T, Yamaguchi,T.P, Birchmeier,W, Kato,S, Yamada,G

Development 136(3) 367-372 2009年2月
Positive regulation of steroidogenic acute regulatory protein gene expression through the interaction between Dlx and GATA-4 for testicular steroidogenesis

Hisayo Nishida, Shinichi Miyagawa, Maxence Vieux-Rochas, Monica Morini, Yukiko Ogino, Kentaro Suzuki, Naomi Nakagata, Hueng-Sik Choi, Giovanni Levi, Gen Yamada

ENDOCRINOLOGY 149(5) 2090-2097 2008年5月
Abnormal urethra formation in mouse models of Split-hand/split-foot malformation type 1 and type 4

Kentaro Suzuki, Ryuma Haraguchi, Tsutomu Ogata, Ottavia Barbieri, Olinda Alegria, Maxence Vieux-Rochas, Naomi Nakagata, Masataka Ito, Alea A. Mills, Takeshi Kurita, Giovanni Levi, Gen Yamada

EUROPEAN JOURNAL OF HUMAN GENETICS 16(1) 36-44 2008年1月
A high-resolution anatomical ontology of the developing murine genitourinary tract (vol 7, pg 680, 2007)

Melissa H. Little, Jane Brennan, Kylie Georgas, Jamie A. Davies, Duncan R. Davidson, Richard A. Baldock, Annemiek Beverdam, John F. Bertram, Blanche Capel, Han Sheng Chiu, Dave Clements, Luise Cullen-McEwen, Jean Fleming, Thierry Gilbert, Doris Herzlinger, Derek Houghton, Matt H. Kaufman, Elena Kleymenova, Peter A. Koopman, Alfor G. Lewis, Andrew P. McMahon, Cathy L. Mendelsohn, Eleanor K. Mitchell, Bree A. Rumballe, Derina E. Sweeney, M. Todd Valerius, Gen Yamada, Yiya Yang, Jing Yu

GENE EXPRESSION PATTERNS 8(1) 47-50 2007年12月
Cessation of gastrulation is mediated by suppression of epithelial-mesenchymal transition at the ventral ectodermal ridge

Sho Ohta, Kentaro Suzuki, Katsuro Tachibana, Hideaki Tanaka, Gen Yamada

DEVELOPMENT 134(24) 4315-4324 2007年12月
Sonic hedgehog expression during early tooth development in Suncus murinus

Mami Miyado, Hidenao Ogi, Gen Yamada, Junzo Kitoh, Takamichi Jogahara, Sen-Icm Oda, Iwao Sato, Kenji Miyado, Masataka Sunohara

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 363(2) 269-275 2007年11月
Regional differences in the functional and biochemical properties of endothelin receptor subtypes in the rabbit prostatic urethra

Yoshihiro Wada, Wataru Takahashi, Jamshid Latifpour, Gen Yamada, Nobuyuki Kai, Jiro Honda, Juro Nakanishi, Robert M. Weiss

BJU INTERNATIONAL 100(2) 430-437 2007年8月
A high-resolution anatomical ontology of the developing murine genitourinary tract

Melissa H. Little, Jane Brennan, Kylie Georgas, Jamie A. Davies, Duncan R. Davidson, Richard A. Baldock, Annemiek Beverdam, John F. Bertram, Blanche Capel, Han Sheng Chiu, Dave Clements, Luise Cullen-McEwen, Jean Fleming, Thierry Gilbert, Doris Herzlinger, Derek Houghton, Matt H. Kaufman, Elena Kleymenova, Peter A. Koopman, Alfor G. Lewis, Andrew P. McMahon, Cathy L. Mendelsohn, Eleanor K. Mitchell, Bree A. Rumballe, Derina E. Sweeney, M. Todd Valerius, Gen Yamada, Yiya Yang, Jing Yu

GENE EXPRESSION PATTERNS 7(6) 680-699 2007年6月
Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling

Ryuma Haraguchi, Jun Motoyama, Hiroshi Sasaki, Yoshihiko Satoh, Shinichi Miyagawa, Naomi Nakagata, Anne Moon, Gen Yamada

DEVELOPMENT 134(3) 525-533 2007年2月
Molecular genetic cascades for external genitalia formation: An emerging organogenesis program

G. Yamada, K. Suzuki, R. Haraguchi, S. Miyagawa, Y. Satoh, M. Kamimura, N. Nakagata, H. Kataoka, A. Kuroiwa, Y. Chen

DEVELOPMENTAL DYNAMICS 235(7) 1738-1752 2006年7月
Cloning and expression analysis of androgen receptor gene in chicken embryogenesis

H Katoh, Y Ogino, G Yamada

FEBS LETTERS 580(6) 1607-1615 2006年3月
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

JH Shim, CC Xiao, AE Paschal, ST Bailey, P Rao, MS Hayden, KY Lee, C Bussey, M Steckel, N Tanaka, G Yamada, S Akira, K Matsumoto, S Ghosh

GENES & DEVELOPMENT 19(22) 2668-2681 2005年11月
【臨床分子内分泌学甲状腺・副甲状腺・骨内分泌代謝系】 FGFs 基礎研究の進展 FGF遺伝子改変動物

宮川信一, 松丸大輔, 上村美佳, 村嶋亜紀, 三原健一郎, 山田源

日本臨床 63(増刊10 臨床分子内分泌学(3)) 492-497 2005年10月