小林和夫 (Kazuo Kobayashi) - マイポータル - researchmap

基本情報

所属: 旧所属大阪市立大学大学院医学研究科基礎医科学専攻（都市医学大講座）教授

学位: 医学博士

J-GLOBAL ID: 200901038560541207
researchmap会員ID: 1000322571

外部リンク: http://www.med.osaka-cu.ac.jp/hostdefense

研究キーワード

3

研究分野

2

学歴

4

委員歴

5

受賞

1

1991年

昭和医学会上条奨学賞

MISC

63

Benzene-extracted components are important for the major activity of diesel exhaust particles - Effect on interleukin-8 gene expression in human bronchial epithelial cells

S Kawasaki, H Takizawa, K Takami, M Desaki, H Okazaki, T Kasama, K Kobayashi, K Yamamoto, K Nakahara, M Tanaka …

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 24(4) 419-426 2001年4月
Proposal of Sphingomonas wittichii sp nov for strain RW1(T), known as a dibenzo-p-dioxin metabolizer

E Yabuuchi, H Yamamoto, S Terakubo, N Okamura, T Naka, N Fujiwara, K Kobayashi, Y Kosako, A Hiraishi

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 51 281-292 2001年3月
Trehalose 6,6 '-dimycolate (Cord factor) of Mycobacterium tuberculosis induces foreign-body- and hypersensitivity-type granulomas in mice

H Yamagami, T Matsumoto, N Fujiwara, T Arakawa, K Kaneda, Yano, I, K Kobayashi

INFECTION AND IMMUNITY 69(2) 810-815 2001年2月
Structure-activity relationship of mycoloyl glycolipids derived from Rhodococcus sp. 4306

S Ueda, N Fujiwara, T Naka, Sakaguchi, I, Y Ozeki, Yano, I, T Kasama, K Kobayashi

MICROBIAL PATHOGENESIS 30(2) 91-99 2001年2月
The immunopathogenesis of delayed-type hypersensitivity.

Microsc. Res. Tech. 53 241-245 2001年
Trehalose 6,6 '-dimycolate (cord factor) of Mycobacterium tuberculosis induces corneal angiogenesis in rats

N Saita, N Fujiwara, Yano, I, K Soejima, K Kobayashi

INFECTION AND IMMUNITY 68(10) 5991-5997 2000年10月
Expression of vascular endothelial growth factor by synovial fluid neutrophils in rheumatoid arthritis (RA)

T Kasama, K Kobayashi, N Yajima, F Shiozawa, Y Yoda, HT Takeuchi, Y Mori, M Negishi, H Ide, M Adachi

CLINICAL AND EXPERIMENTAL IMMUNOLOGY 121(3) 533-538 2000年9月
Nuclear factor-kappa B activation in silica-induced interleukin 8 production by human bronchial epithelial cells

M Desaki, H Takizawa, T Kasama, K Kobayashi, Y Morita, K Yamamoto

CYTOKINE 12(8) 1257-1260 2000年8月
In vivo administration of mycobacterial cord factor (trehalose 6,6'-dimycolate) can induce lung and liver granulomas and thymic atrophy in rabbits

N Hamasaki, KI Isowa, K Kamada, Y Terano, T Matsumoto, T Arakawa, K Kobayashi, Yano, I

INFECTION AND IMMUNITY 68(6) 3704-3709 2000年6月
Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis

J Lu, T Kasama, K Kobayashi, Y Yoda, F Shiozawa, M Hanyuda, M Negishi, H Ide, M Adachi

JOURNAL OF IMMUNOLOGY 164(11) 5922-5927 2000年6月
Mycobacterium leprae typing by genomic diversity and global distribution of genotypes

M Matsuoka, S Maeda, M Kai, N Nakata, GT Chae, TP Gillis, K Kobayashi, S Izumi, Y Kashiwabara

INTERNATIONAL JOURNAL OF LEPROSY AND OTHER MYCOBACTERIAL DISEASES 68(2) 121-128 2000年6月
Erythromycin suppresses nuclear factor-kB and activator protein-1 activation in human bronchial epithelial cells.

Biochem. Biophys. Res. Commun. 267(1) 124-128 2000年
A novel sphingolipid containing galacturonic acid and 2-hyroxy fatty acid in cellular lipids of Sphingomonas yanoikuyae.

J. Bacteriol. 182(9) 2660-2663 2000年
Diesel exhaust particles induce NF-kappa B activation in human bronchial epithelial cells in vitro: Importance in cytokine transcription

H Takizawa, T Ohtoshi, S Kawasaki, T Kohyama, M Desaki, T Kasama, K Kobayashi, K Nakahara, K Yamamoto, K Matsushima …

JOURNAL OF IMMUNOLOGY 162(8) 4705-4711 1999年4月
Diaminodiphenylsulfone resistance of Mycobacterium leprae due to mutations in the dihydropteroate synthase gene, (共著)

FEMS Microbiology Letters 177(2) 231-235 1999年
Synovial fluid neutrophil expression of interleukin 8 in rheumatoid arthritis, (共著)

Japanese Journal of Rheumatology 9 175-187 1999年
Macrophage inflammation protein 1 alpha expression by synovial fluid neutrophils in rheumatoid arthritis, (共著)

Annals of Rheumatic Disease 58 297-302 1999年
Biphasic regulation of the development of murine type (]G0025[) collagen-induced arthritis by interleukin-12. Possible involvement of endogenous interleukin-10 and tumor necrosis factor α.

Arthritis Rheum. 42 100-109 1999年
The possible role of interleukin (IL)-12 and interferon-gamma-inducing factor IL-18 in protection against experimental Mycobacterium leprae infection in mice

K Kobayashi, M Kai, M Gidoh, N Nakata, M Endoh, RP Singh, T Kasama, H Saito

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY 88(3) 226-231 1998年9月
Expression of chemokines and induction of rapid cell death in human blood neutrophils by Mycobacterium tuberculosis

K Kasahara, Sato, I, K Ogura, H Takeuchi, K Kobayashi, M Adachi

JOURNAL OF INFECTIOUS DISEASES 178(1) 127-137 1998年7月

もっとみる

書籍等出版物

2

Clinical Mycobacteriology, (共著)

Prous Science 1998年
Basic Mechanisms of Granulomatous Inflammation, (共著)

Elsevier 1989年

所属学協会

9

Works(作品等)

2

抗酸菌感染症における宿主防御機構の解明

1997年 - 1999年
Mechanisms of host defense against mycobacterial infection

1997年 - 1999年

共同研究・競争的資金等の研究課題

9

新規ワクチン開発

その他の研究制度
自己免疫疾患の病因

その他の研究制度
びまん性肺疾患の分子機序

その他の研究制度
薬剤耐性抗酸菌感染症の新規治療戦略

その他の研究制度
抗酸菌感染における宿主応答

その他の研究制度
Development of new vaccines against infectious diseases

The Other Research Programs
Molecular mechanisms of diffuse lung diseases

The Other Research Programs
New therapeutic strategies for controlling drug-resistant mycobacterial infection

The Other Research Programs
Host responses to mycobacterial infection

The Other Research Programs