池内俊彦 (Toshihiko Ikeuchi) - マイポータル

基本情報

J-GLOBAL ID: 200901054004781970
researchmap会員ID: 1000326167

外部リンク: http://www.warp.or.jp/~ikeuchi

研究分野

経歴

学歴

MISC

136

Apoptosis-inducing activity of endocrine-disrupting chemicals in cultured PC12 cells.

H. Sasaya, Toyama Univ, K. Yasuzumi, H. Maruoka, Kurab, A. Fujita, Y. Kato, T. Waki, K. Shimoke, T. Ikeuchi

Advances in Biological Chemistry 2, 92-105 2012年5月
New orally bioavailable 2-aminobenzamide-type histone deacetyase inhibitor promotes neurite outgrowth via histone H3 modification in PC12 cells: a possible therapeutic candidate for neuronal diseases.

H. Maruoka, Kurabo, R. Hosokawa, Y. Hirata, H. Kawa, K. Okamoto, T. Waki, S. Uesato, T. Ikeuchi, K. Shimoke

Journal of Bioengineering and Biomedical Science S5, 1-5 2012年3月
Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons

Hiroki Maruoka, Harue Sasaya, Kensuke Sugihara, Koji Shimoke, Toshihiko Ikeuchi

JOURNAL OF BIOCHEMISTRY 150(5) 473-475 2011年11月
Appearance of Nuclear-sorted Caspase-12 Fragments in Cerebral Cortical and Hippocampal Neurons in Rats Damaged by Autologous Blood Clot Embolic Brain Infarctions

Koji Shimoke, Yoshinori Matsuki, Kenji Fukunaga, Yoshinobu Matsumura, Eriko Fujita, Kensuke Sugihara, Masamichi Nobuhara, Hiroki Maruoka, Toshihiko Ikeuchi, Motoshige Kudo

CELLULAR AND MOLECULAR NEUROBIOLOGY 31(5) 795-802 2011年7月
ANALYSIS OF THE ROLE OF NERVE GROWTH FACTOR IN PROMOTING CELL SURVIVAL DURING ENDOPLASMIC RETICULUM STRESS IN PC12 CELLS

Koji Shimoke, Harue Sasaya, Toshihiko Ikeuchi

METHODS IN ENZYMOLOGY: UNFOLDED PROTEIN RESPONSE AND CELLULAR STRESS, VOL 490, PT B 490 53-70 2011年
Dibutyryl-cAMP up-regulates nur77 expression via histone modification during neurite outgrowth in PC12 cells

Hiroki Maruoka, Harue Sasaya, Yuichi Shimamura, Yosuke Nakatani, Koji Shimoke, Toshihiko Ikeuchi

JOURNAL OF BIOCHEMISTRY 148(1) 93-101 2010年7月
Nerve growth factor attenuates 2-deoxy-D-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78

Soichiro Kishi, Koji Shimoke, Yosuke Nakatani, Takafumi Shimada, Nobuaki Okumura, Katsuya Nagai, Kazuo Shin-ya, Toshihiko Ikeuchi

NEUROSCIENCE RESEARCH 66(1) 14-21 2010年1月
Protection from ER stress-mediated apoptosis by the neurotrophins.

K. Shimoke, K. Fukunaga, Y. Matsumura, M. Kudo, Tokyo Med. Univ, T. Ikeuchi

Current Topics in Biochemical Research 11, 19-28. 2009年12月
Caspase-3 activation and lipid peroxidation are important for apoptotic cell death in cerebral infarction.

K. Shimoke, I, Yamazaki Y, Matsuki T, Ikeuchi M. Kudo

Journal of Tokyo Medical University 67, 15-21 2009年
Caspase-3 activation and lipid peroxidation are important for apoptotic cell death in cerebral infarction.

K. Shimoke, I, Yamazaki Y, Matsuki T, Ikeuchi M. Kudo

Journal of Tokyo Medical University 67, 15-21 2009年
ER stress is the initial response to polyglutamine toxicity in PC12 cells

Hitoshi Nakayama, Masashi Hamada, Nobuhiro Fujikake, Yoshitaka Nagai, Jing Zhao, Osamu Hatano, Koji Shimoke, Minoru Isosaki, Masanori Yoshizumi, Toshihiko Ikeuchi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 377(2) 550-555 2008年12月
ER stress is the initial response to polyglutamine toxicity in PC12 cells

Hitoshi Nakayama, Masashi Hamada, Nobuhiro Fujikake, Yoshitaka Nagai, Jing Zhao, Osamu Hatano, Koji Shimoke, Minoru Isosaki, Masanori Yoshizumi, Toshihiko Ikeuchi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 377(2) 550-555 2008年12月
Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells

Harue Sasaya, Takahiro Utsumi, Koji Shimoke, Hitoshi Nakayama, Yoshinobu Matsumura, Kenji Fukunaga, Toshihiko Ikeuchi

JOURNAL OF BIOCHEMISTRY 144(2) 251-257 2008年8月
Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells

Harue Sasaya, Takahiro Utsumi, Koji Shimoke, Hitoshi Nakayama, Yoshinobu Matsumura, Kenji Fukunaga, Toshihiko Ikeuchi

JOURNAL OF BIOCHEMISTRY 144(2) 251-257 2008年8月
p-nonylphenol induces endoplasmic reticulum stress-mediated apoptosis in neuronally differentiated PC12 cells

Takashi Kusunoki, Koji Shimoke, Satoko Komatsubara, Soichiro Kishi, Toshihiko Ikeuchi

NEUROSCIENCE LETTERS 431(3) 256-261 2008年2月
p-nonylphenol induces endoplasmic reticulum stress-mediated apoptosis in neuronally differentiated PC12 cells

Takashi Kusunoki, Koji Shimoke, Satoko Komatsubara, Soichiro Kishi, Toshihiko Ikeuchi

NEUROSCIENCE LETTERS 431(3) 256-261 2008年2月
神経系小胞体ストレスと誘導型アポトーシスのニコチンとニューロトロフィンによる防御機構

池内俊彦, 下家浩二

第11回関西大学先端科学技術シンポジウム講演集 109-116 2007年
Opposing mechanism of extracellular signal-regulated kinases on hydrogen peroxide-induced apoptosis in PC12 cells.

IKEUCHI Toshihiko, K, Shimoke M. Kudo

Journal of Tokyo Medical University 65, 283-289 2007年
Opposing mechanism of extracellular signal-regulated kinases on hydrogen peroxide-induced apoptosis in PC12 cells.

IKEUCHI Toshihiko, K, Shimoke M. Kudo

Journal of Tokyo Medical University 65, 283-289 2007年
Synthesis and cancer antiproliferative activity of new histone deacetylase inhibitors: hydrophilic hydroxamates and 2-aminobenzamide-containing derivatives

Y. Nagaoka, T. Maeda, Y. Kawai, D. Nakashima, T. Oikawa, K. Shimoke, T. Ikeuchi, H. Kuwajima, S. Uesato

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 41(6) 697-708 2006年6月

もっとみる

書籍等出版物

小胞体ストレス誘導型アポトーシスとその細胞内防御機構－脳神経細胞の死による疾患とその治療戦略立案の可能性－

理工学と技術 2007年
小胞体ストレス誘導型アポトーシスとその細胞内防御機構－脳神経細胞の死による疾患とその治療戦略立案の可能性－

2007年
Endoplasmic reticulum stress-induced apoptosis and its prevention by neurotrophins.

New Trends in Brain Research 2006年
Endoplasmic reticulum stress-induced apoptosis and its prevention by neurotrophins.

New Trends in Brain Research 2006年
タンパク質の生命科学－ポスト・ゲノム時代の主役－

中央公論新社 2001年
生命を学ぶタンパク質の科学

オーム社 1999年
タンパク質ものがたり-私たちの生命を支えるもの-

化学同人 1998年
タンパク質-生命を支える物質-

大阪大学 1996年
絵ときタンパク質と遺伝子

オーム社 1996年

講演・口頭発表等

New orally bioavailable HDAC inhibitor promotes neurite outgrowth in PC12 cell.

第6回日本エピジェネティクス研究会 2012年
Subtype specific mechanisms of neurite outgrowth and cell survival by HDAC families in PC12 cells.

第34回日本分子生物学会年会 2011年
Nerve growth factor decreases ER stress-mediated apoptosis through refolding unfolded protein structure by glucose-regulated protein 78 in PC12 cells.

Society for Neuroscience's 41st Annual Meeting 2011年
Apoptosis-inducing activity of endocrine-disrupting chemicals in cultured PC12 cells.

第84回日本生化学会大会 2011年
Forskolin suppresses ER stress-mediated apoptosis via enhanced expression of GRP78 by non-PI3-kinase pathway in PC12 cells.

第84回日本生化学会大会 2011年
Involvement of nur77 gene product in neurite outgrowth induced by dibutyryl cAMP and trichostatin A in PC12 cells.

第84回日本生化学会大会 2011年
Mechanism by which HDAC inhibitors suppress ER stress-induced apoptosis.

第5回日本エピジェネティクス研究会 2011年
Comparison between apoptosis-inducing effect and estrogen-like effect of endocrine-disrupting chemicals in cultured PC12 cells.

日本環境ホルモン学会第13回研究発表会 2010年
Comparison between apoptosis-inducing effect and estrogen-like effect of endocrine-disrupting chemicals in cultured PC12 cells.

Congress of Biochemistry and Molecular Biology 2010 2010年
Nerve growth factor decreases ER stress-induced apoptosis through down-regulation of PUMA and Bim in PC12 cells.

Society for Neuroscience' s 40th Annual Meeting 2010年
Regulatory effect of NGF on apoptosis and autophagy induced by tunicamycin with chloroquine in PC12 cells.

第53回日本神経化学会大会 2010年
Action of NGF signal on autophagy-related proteins.

日本分子生物学会第10回春季シンポジウム 2010年
Nicotine suppresses tunicamycin-induced GRP78 expression during ER stress-mediated apoptosis via preventing a common step upstream of Ire1-XBP1 and ATF6 pathways in PC12 cells

Congress of Biochemistry and Molecular Biology 2008 Abstracts 2008年
イネのセリンラセマーゼ：Mg2+による構造変化と２酵素活性の制御

第25回微量栄養素研究会シンポジウム 2008年
Nerve growth factor attenuates 2-deoxyglucose-triggered endoplasmic reticulum-mediated apoptosis via enhanced induction of GRP78 expression

第51回日本神経化学会年会 2008年
Nicotine suppresses tunicamycin-induced GRP78 expression during ER stress-mediated apoptosis via preventing a common step upstream of Ire1-XBP1 and ATF6 pathways in PC12 cells

Congress of Biochemistry and Molecular Biology 2008 Abstracts 2008年
Nerve growth factor attenuates 2-deoxyglucose-triggered endoplasmic reticulum-mediated apoptosis via enhanced induction of GRP78 expression

2008年
Polyglutamine-expanded protein-induced ER stress-mediated apoptosis and its suppression by NGF

第80回日本生化学会第30回日本分子生物学会合同年会2007 2007年
Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced expression during ER stress-mediated apoptosis in PC12 cells

第80回日本生化学会第30回日本分子生物学会合同年会2007 2007年
Nerve growth factor attenuates 2-deoxyglucose-triggered endoplasmic reticulum-mediated apoptosis viaup-regulation of GRP78 expression

第80回日本生化学会第30回日本分子生物学会合同年会2007 2007年

池内俊彦

基本情報

研究分野

経歴

学歴

MISC

書籍等出版物

講演・口頭発表等

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

産業財産権

メニュー