Atsuko Sehara

Profile Information

Affiliation: Institute for Frontier Medical Sciences, Field of Regeneration Control,Department of Growth Regulation, Kyoto University

Degree: Ph. D(Kyoto University)

J-GLOBAL ID: 200901054654187666
researchmap Member ID: 1000326586

External link: http://www.frontier.kyoto-u.ac.jp/rc03/index-jhtml.

Research Interests

Research Areas

Research History

1999 - 2000

東京都臨床医学総合研究所・室長
1999 - 2000

The Tokyo Metropolitan Inst. of Med. Sci
1988 - 1998

国立精神神経センター・神経研究所・室長
1988 - 1998

Inst. Newrosci. , National Center of Newrologyad Psycliatry

Education

- 1982

Kyoto University
- 1982

Graduate School, Division of Medicine, Kyoto University

Papers

Anteroposterior molecular registries in ectoderm of the echinus rudiment

Adachi S, Niimi I, Sakai Y, Sato F, Minokawa T, Urata M, Sehara-Fujisawa A, Kobayashi I, Yamaguchi M

Dev Dyn, 247(12) 1297-1307, Dec, 2018 Peer-reviewed
Integrin β1 activity is required for cardiovascular formation in zebrafish

Iida A, Wang Z, Hirata H, Sehara-Fujisawa A

Genes Cells, 23(11) 938-951, Nov, 2018 Peer-reviewed
Focal adhesions are essential to drive zebrafish heart valve morphogenesis

Felix Gunawan, Alessandra Gentile, Ryuichi Fukuda, Ayele Taddese Tsedeke, Vanesa Jimenez-Amilburu, Radhan Ramadass, Atsuo Iida, Atsuko Sehara-Fujisawa, Didier Stainier

J Cell Biol, in press, 2018 Peer-reviewed
Secretome analysis to elucidate metalloprotease-dependent ectodomain shedding of glycoproteins during neuronal differentiation

Kazuya Tsumagari, Kyoko Shirakabe, Mayu Ogura, Fuminori Sato, Yasushi Ishihama, Atsuko Sehara-Fujisawa

GENES TO CELLS, 22(2) 237-244, Feb, 2017 Peer-reviewed
The Sal-like 4 - integrin α6β1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells.

Itou J, Tanaka S, Li W, Iida A, Sehara-Fujisawa A, Sato F, Toi M

Biochimica et biophysica acta, 1864(1) 76-88, Jan, 2017 Peer-reviewed
Generation of a transgenic medaka (Oryzias latipes) strain for visualization of nuclear dynamics in early developmental stages

Takanobu Inoue, Atsuo Iida, Shingo Maegawa, Atsuko Sehara-Fujisawa, Masato Kinoshita

DEVELOPMENT GROWTH & DIFFERENTIATION, 58(9) 679-687, Dec, 2016 Peer-reviewed
Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo

Aosa Kamezaki, Fuminori Sato, Kazuhiro Aoki, Kazuhide Asakawa, Koichi Kawakami, Fumio Matsuzaki, Atsuko Sehara-Fujisawa

SCIENTIFIC REPORTS, 6 28873, Jul, 2016 Peer-reviewed
ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage without developmental defects

Yudai Tokumasu, Atsuo Iida, Zi Wang, Satoshi Ansai, Masato Kinoshita, Atsuko Sehara-Fujisawa

DEVELOPMENT GROWTH & DIFFERENTIATION, 58(4) 409-421, May, 2016 Peer-reviewed
Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells

Emi Shoji, Hidetoshi Sakurai, Tokiko Nishino, Tatsutoshi Nakahata, Toshio Heike, Tomonari Awaya, Nobuharu Fujii, Yasuko Manabe, Masafumi Matsuo, Atsuko Sehara-Fujisawa

SCIENTIFIC REPORTS, 5 12831, Aug, 2015 Peer-reviewed
High-resolution live imaging reveals axon-glia interactions during peripheral nerve injury and repair in zebrafish

Yan Xiao, Adele Faucherre, Laura Pola-Morell, John M. Heddleston, Tsung-Li Liu, Teng-Leong Chew, Fuminori Sato, Atsuko Sehara-Fujisawa, Koichi Kawakami, Hernan Lopez-Schier

DISEASE MODELS & MECHANISMS, 8(6) 553-564, Jun, 2015 Peer-reviewed
Mest but Not MiR-335 Affects Skeletal Muscle Growth and Regeneration

Yosuke Hiramuki, Takahiko Sato, Yasuhide Furuta, M. Azim Surani, Atsuko Sehara-Fujisawa

PLOS ONE, 10(6) e0130436, Jun, 2015 Peer-reviewed
Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain

Tomomi Sato, Fuminori Sato, Aosa Kamezaki, Kazuya Sakaguchi, Ryoma Tanigome, Koichi Kawakami, Atsuko Sehara-Fujisawa

PLOS ONE, 10(5) e0127360, May, 2015 Peer-reviewed
ADAM12 Produced by Tumor Cells Rather than Stromal Cells Accelerates Breast Tumor Progression

Camilla Frohlich, Camilla Nehammer, Reidar Albrechtsen, Pauliina Kronqvist, Marie Kveiborg, Atsuko Sehara-Fujisawa, Arthur M. Mercurio, Ulla M. Wewer

MOLECULAR CANCER RESEARCH, 9(11) 1449-1461, Nov, 2011 Peer-reviewed
Generation of a monoclonal antibody reactive to prefusion myocytes

Tomohiro Kurisaki, Aki Masuda, Shiho Nakagiri, Yoshihiro Hayata, Motoki Kuhara, Yoshiro Kishi, Atsuko Sehara-Fujisawa

JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 32(1) 31-38, Aug, 2011 Peer-reviewed
ERK5 Regulates Muscle Cell Fusion through Klf Transcription Factors

Kazunori Sunadome, Takuya Yamamoto, Miki Ebisuya, Kunio Kondoh, Atsuko Sehara-Fujisawa, Eisuke Nishida

DEVELOPMENTAL CELL, 20(2) 192-205, Feb, 2011 Peer-reviewed
Metalloprotease-Dependent Onset of Blood Circulation in Zebrafish

Atsuo Iida, Kazuya Sakaguchi, Kiyoaki Sato, Hidetoshi Sakurai, Daigo Nishimura, Aya Iwaki, Miki Takeuchi, Makoto Kobayashi, Kazuyo Misaki, Shigenobu Yonemura …

CURRENT BIOLOGY, 20(12) 1110-1116, Jun, 2010 Peer-reviewed
A Disintegrin and Metalloprotease 12 (ADAM12) Is a Prognostic Factor in Resected Pathological Stage I Lung Adenocarcinoma

Nobuya Mino, Ryo Miyahara, Ei Nakayama, Tsuyoshi Takahashi, Ayuko Takahashi, Shotaro Iwakiri, Makoto Sonobe, Kenichi Okubo, Toshiki Hirata, Atsuko Sehara …

JOURNAL OF SURGICAL ONCOLOGY, 100(3) 267-272, Sep, 2009 Peer-reviewed
Roles of Meltrin-beta/ADAM19 in Progression of Schwann Cell Differentiation and Myelination during Sciatic Nerve Regeneration

Shuji Wakatsuki, Norihiro Yumoto, Koji Komatsu, Toshiyuki Araki, Atsuko Sehara-Fujisawa

JOURNAL OF BIOLOGICAL CHEMISTRY, 284(5) 2957-2966, Jan, 2009 Peer-reviewed
Phenotypic analysis of Meltrin alpha (ADAM12)-deficient mice: Involvement of Meltrin alpha in adipogenesis and myogenesis

T Kurisaki, A Masuda, K Sudo, J Sakagami, S Higashiyama, Y Matsuda, A Nagabukuro, A Tsuji, Y Nabeshima, M Asano …

MOLECULAR AND CELLULAR BIOLOGY, 23(1) 55-61, Jan, 2003 Peer-reviewed
Meltrin beta mini, a new ADAM19 isoform lacking metalloprotease and disintegrin domains, induces morphological changes in neuronal cells

T Kurisaki, S Wakatsuki, A Sehara-Fujisawa

FEBS LETTERS, 532(3) 419-422, Dec, 2002 Peer-reviewed

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