TANAKA Tomohiro

J-GLOBAL         Last updated: Sep 10, 2019 at 13:46
 
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Name
TANAKA Tomohiro
E-mail
tttanakamed.nagoya-cu.ac.jp
Affiliation
Nagoya City University
Section
Graduate School of Medical Sciences Department of Gastroenterology and Metabolism
Job title
Assistant Professor
Degree
Ph.D.(Kyoto University), M.D.(Kyoto University)

Research Areas

 
 

Academic & Professional Experience

 
2008
 - 
Today
 Assistant professor, Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine
 
2008
 - 
2008
 JSPS Research fellow
 
2007
 - 
2008
 Postdoctoral fellow, Kyoto University COE program
 
2005
 - 
2007
 Clinical Fellow, Division of Endocrinology and Metabolism, Kyoto University Hospital
 
1999
 - 
2001
 Resident, Kitano Hospital, Osaka
 

Education

 
 
 - 
2005
Endocrinology and Metabolism, Graduate School, Division of Medicine, Kyoto University
 
 
 - 
1998
Faculty of Medicine, Faculty of Medicine, Kyoto University
 

Committee Memberships

 
2008
   
 
Japan Endocrine Society  Delegate
 
2007
   
 
Japanese Association for the Study of Obesity  Delegate
 

Awards & Honors

 
2007
Young Investigator Award, The Society of Cardiovascular Endocrinology and Metabolism
 
2007
Imura Special Award
 
2007
Young Investigator Award, Japanese Society of Molecular Medicine
 
2006
Young Investigator Award, Japan Endocrine Society
 
2005
Keystone Symposia Scholarship Award
 

Published Papers

 
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles:a multi-center evaluation
Channabasavaiah B.Gurumurthy , Aidan R.O’Brien , Rolen M.Quadros , John Adams Jr , Pilar Alcaide , Shinya Ayabe , Johnathan Ballard , Surinder K.Batra , Marie-Claude Beauchamp , Kathaleen A.Becker , Guillaume Bernas , David Brough , Francisco Carrillo-Salinas , Wesley Chan , Hanying Chen , Ruby Dawson , Victoria DeMambro , Jinke D’Hont , Katharine M.Dibb , James D.Eudy , Lin Gan , Jing Gao , Amy Gonzales , Anyonya R.Guntur , Huiping Guo , Donald W.Harms , Anne .Harrington , Kathryn E.Hentges , Neil Humphyreys , Shiho Imai , Hideshi Ishii , Mizuho Iwama , Eric Jonasch , Michaelle Karolak , Bernard Keavney , Nay-Chi Khin , Masamitsu Konno , Yuko Kotani , Yayoi Kunihiro , Imayavaramban Lakshmanan , Catherine Laochelle , Catherine B.Lawrence , Lin Li , Volkhard Lindner , Xian-De Liu , Gloria Lopez-Castejon , Andrew Loudon , Jenna Lowe , Loydie A.Jerome-Majewska , Taiji Matsusaka , Hiromi Miura , Yoshiki Miyasaka , Benjamin Morpurgo , Katherine Motyl , Yo-ichi Nabeshima , Koji Nakade , Toshiaki Nakashiba , Kenidhi Nakashima , Yuishi Obata , Sanae Ogiwara , Mariette Ouellet , Leif Oxburgh , Sandra Piltz , Ilka Pinz , Moorthy P.Ponnusamy , David Ray , Ronald J.States , Lora Strrs , Fumihiro Sugiyama , Satoru Takahashi , Tomohiro Tanaka , Andrew W.Trafford , Yoshihiro Uno , Leen Vanhoutte , Frederique Vanrockeghem , Brandon J.Willis , Christian S.Wright , Yuko Yamauchi , Xin Yi , Kazuto Yoshimi , Xuesong Zhang , Yu Zhang , Masato Ohtsuka , Styabrata Das , Daniel J.Garry , Tino Hochepied , Paul Thoms , Jan Parker-Thornburg , Antony D.Adamson , Atsushi Yoshik , Jean-Francois Schmouth , Andrei Golovko , William R. Thompson , K.C.Kent Lloyd , Joshua A. Wood , Mitra Cowan , Tomoji Mashimo ,Seiya Mizuno , Hao Zhu , Petr Kasparek , Luc Liaw , Joseph M. Miano, Gaetan Burgio
Genome Biology   20(171)    Jun 2019   [Refereed]
Re-Evaluating One-step Generation of Mice Carrying Conditional Alleles by CRISPR-Cas9-Mediated Genome Editing Technology
Channabasavaiah Gurumurthy, Rolen Quadros, John Adams Jr, Pilar Alcaide, Shinya Ayabe, Johnathan Ballard, Surinder K. Batra, Marie-Claude Beauchamp, Kathleen A Becker, Guillaume Bernas, David Brough, Francisco Carrillo-Salinas, Ruby Dawson, Victoria DeMambro, Jinke D’Hont, Katharine Dibb, James D. Eudy, Lin Gan, Jing Gao, Amy Gonzales, Anyonya Guntur, Huiping Guo, Donald W. Harms, Anne Harrington, Kathryn E. Hentges, Neil Humphreys, Shiho Imai, Hideshi Ishii, Mizuho Iwama, Eric Jonasch, Michelle Karolak, Bernard Keavney, Nay-Chi Khin, Masamitsu Konno, Yuko Kotani, Yayoi Kunihiro, Imayavaramban Lakshmanan, Catherine Larochelle, Catherine B. Lawrence, Lin Li, Volkhard Lindner, Xian-De Liu, Gloria Lopez-Castejon, Andrew Loudon, Jenna Lowe, Loydie Jerome-Majeweska, Taiji Matsusaka, Hiromi Miura, Yoshiki Miyasaka, Benjamin Morpurgo, Katherine Moty, Yo-ichi Nabeshima, Koji Nakade, Toshiaki Nakashiba, Kenichi Nakashima, Yuichi Obata, Sanae Ogiwara, Mariette Ouellet, Leif Oxburgh, Sandra Piltz, Ilka Pinz, Moorthy P. Ponnusamy, David Ray, Ronald J. Redder, Clifford J Rosen, Nikki Ross, Mark T. Ruhe, Larisa Ryzhova, Ane M. Salvador, Radislav Sedlacek, Karan Sharma, Chad Smith, Katrien Staes, Lora Starrs, Fumihiro Sugiyama, Satoru Takahashi, Tomohiro Tanaka, Andrew Trafford, Yoshihiro Uno, Leen Vanhoutte, Frederique Vanrockeghem, Brandon J. Willis, Christian S. Wright, Yuko Yamauchi, Xin Yi, Kazuto Yoshimi, Xuesong Zhang, Yu Zhang, Masato Ohtsuka, Satyabrata Das, Daniel J. Garry, Tino Hochepied, Paul Thomas, Jan Parker-Thornburg, Antony D Adamson, Atsushi Yoshiki, Jean-Francois Schmouth, Andrei Golovko, William R. Thompson, KC. Kent Lloyd, Joshua A. Wood, Mitra Cowan, Tomoji Mashimo, Seiya Mizuno, Hao Zhu, Petr Kasparek, Lucy Liaw, Joseph M. Miano, Gaetan Burgio
bioRxiv      Sep 2018
CRISPR/Cas9-mediated Angpt18 knockout wuppresses plasma triglyceride concentrations and adiposity in rats
R.Iaumi, T.Kusakabe, M.Noguchi, H.Iwakura, T.Tanaka, T Miyazawa, D.Aotani, K.Hosoda, K.Kangawa, K.Nakao
J.Lipid Res.   59(9) 1575-1585   Jul 2018   [Refereed]
Switching of other dipeptidyl peptidase 4 inhibitors to alogliptin improves glycemic control in Japanese patients with type2 diabetes mellitus.
T. Yagi, T. Tanaka, Y. Hayashi, T. Mizuno, K. Ogawa, H. Koyama, K. Imaeda, T. Joh.
Nagoya Medical Journal      Jan 2018   [Refereed]
A Case of Euthyroid Graves’ Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody
A. Hotta, T. Tanaka, H. Kato, S. Kakoi, Y. Shimizu, C. Hasegawa, A. Hayakawa, S. Yasuda, K. Ogawa, S. Ito, H. Ohguchi, T. Yagi, H. Koyama, M. Kawamura, K. Sugitani, Y. Ogura, T. Joh, and K. Imaeda. (Corresponding author)
Case Rep Endocrinol      2018   [Refereed]
CLICK: one-step generation of conditional knockout mice
Y. Miyasaka, Y. Uno, K. Yoshimi, Y. Kunihiro, T. Yoshimura, T. Tanaka, H. Ishikubo, Y. Hiraoka, N. Takemoto, T. Tanaka, Y. Ooguchi, P. Skehel, T. Aida, J. Takeda, T. Mashimo.
BMC Genomics   19(1) 318   2018   [Refereed]
Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways.
T. Yagi, E. Kubota, H. Koyama, T. Tanaka, H. Kataoka, K. Imaeda, T. Joh.
Oncotarget   9(12) 10650-10664   2018   [Refereed]
H. Ohguchi, K. Imaeda, A. Hotta, S. Kakoi, S. Yasuda, Y. Shimizu, A. Hayakawa, H. Mishima, C. Hasegawa, S. Ito, K. Ogawa, Y. Yagi, H. Koyama, T. Tanaka, H. Kato, S.Takahashi, T. Joh.
Internal Medicine      2018   [Refereed]
Koyama H, Tanaka T, Imaeda K
BMJ case reports   2017    Aug 2017   [Refereed]
Nakayama Y, Masuda Y, Ohta H, Tanaka T, Washida M, Nabeshima YI, Miyake A, Itoh N, Konishi M
Scientific reports   7(1) 330   Mar 2017   [Refereed]

Misc

 
Omics-based molecular pathology of the hypothalamus in murine models of obesity
Tomohiro Tanaka
Kyoto Conferebce of Young Lions in Obesity Research      Oct 2015
Dynamism of the hypothalamic transcriptome uncoverd "stages" during the development of diet-induced obesity in mice
Takuhiro Sonoyama,Tomohiro Tanaka,Hiroshi Sawada,Masafumi Inoue,Yohei Ogino,Tingting Guo,Kazuwa Nakao
Kyoto Conference of Young Lions in Obesity Research      Oct 2015
K.-I. Tomiyama; R. Maeda; I. Urakawa; Y. Yamazaki; T. Tanaka; S. Ito; Y. Nabeshima; T. Tomita; S. Odori; K. Hosoda; K. Nakao; A. Imura; Y.-I. Nabeshima
Proceedings of the National Academy of Sciences of the United States of America   107(4) 1666-1671   Jan 2010   [Refereed]
Distinct Roles of Intra-and Extrahepatic β-Klotho in Regulating Plasma Triglyceride Level and Body Weight in Mice
K Kobayashi,T Tanaka,Y Nabeshima
International Congress of Endocrinology      Jun 2014

Conference Activities & Talks

 
Spatio-temporal Signature of Hypothalamic Transcriptome in Obesity
TANAKA Tomohiro
79thScientific sessions,San Francisco,CA(America)   10 Jun 2019   
Multi-Omics-Based Spatio-Temporal Signatures of Hypothalamic Pathology in Obesity
TANAKA Tomohiro
The 11th Scientific Meeting of the Asian Association for the Study of Diabetes 仙台   23 Mar 2019   
Spatio-Temporal Signatures of Hypothalamic Transcriptome/Metabolome in Obesity
T Tanaka, T Sonoyama, K Kaneko, H Koyama, D Aotani, Y Nabeshima, K Nakao
2nd International Syomposium of Kyoto Biomolecular Mass Spectrometry Society   3 Feb 2018   
Spatio-Temporal Signatures of Hypothalamic Transcriptome/Metabolome in Obesity
T. Tanaka, T. Sonoyama, K.Kaneko, T. Unzai, Y.Ogino, T. Guo, K.Kobayashi, H. Koyama, D. Aotani, K. Imada, K.Nakao.
35th Annual Scientific Meeting of the Obesity Society   1 Nov 2017   
Role of Dietary Linoleic Acid in the Development of Obesity--A Multiomics Analysis
T Tanaka, M Inoue, T Sonoyama, Y Ogino, T Guo, H Koyama, K Nakao
34th Annual Scientific Meeting of The Obesity Society   3 Nov 2016   

Research Grants & Projects

 
Novel mechanisms linking metabolism and ageing - approach from klotho research
Project Year: 2008 - 2010
Molecular basis for the dysregulation of adipocyte-brain signaling in metabolic syndrome
Project Year: 2006 - 2007

Patents

 
メタボリックシンドローム予防又は治療薬
特開2007-112720(P2007-112720A)