NISHIYAMA Akira

J-GLOBAL         Last updated: Jul 10, 2019 at 11:58
 
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Name
NISHIYAMA Akira
Affiliation
Kagawa University
Section
Faculty of Medicine
Job title
Professor
Degree
1993: M.D. Kagawa Medical University, 1999: Ph.D. Kagawa Medical University, 医学博士(Kagawa Medical University)

Research Areas

 
 

Academic & Professional Experience

 
2018
 - 
Today
香川大学
 
2015
 - 
Today
香川大学
 
2011
 - 
Today
Visiting Professor, Chinese Academy of Medical Science
 
2007
 - 
Today
香川大学
 
2002
 - 
2007
Adjunct Faculty, Health Sciences Center, Tulane University, School of Medicine
 
2000
 - 
2002
Assistant Professor, Department of Pharmacology, Kagawa Medical University
 
2000
 - 
2002
Visiting Assistant Professor, Department of Physiology, Tulane University Health Sciences Center
 
1998
 - 
2001
Postdoctoral Fellow, Department of Physiology, Tulane University, School of Medicine
 
1994
 - 
1995
Senior Assistant Resident, Department of Anesthesiology and ICU, National Iwakuni Hospital
 
1993
 - 
1994
Junior Assistant Resident, Medical School,Department of Anesthesiology and ICU,, Okayama University
 

Education

 
 
 - 
1999
生体制御部門, Graduate School, Division of Medical Science, Kagawa Medical University
 
 
 - 
1993
医学科, Faculty of Medicine, Kagawa Medical University
 

Awards & Honors

 
1999
米国生理学会/The Hoecht Marion Roussel Excellence Award
 
2000
Young Investigator Travel Award: The 18th Scientific Meeting of the International Society of Hypertension
 
2000
米国医学研究会/Best Trainee Award
 
2000
国際高血圧学会/Young Investigator Award
 
2001
Young Investigator Award: Southern AFMR/ SCI Scientific Meetings.
 
2001
Bristol Squibb Recognition Awards for Young Investigators: The American Society of Hypertension
 
2001
Young Investigator Award: Japanese Association of Cardiovascular Pharmacology
 
2001
米国高血圧学会/Bristol Squibb Recognition Award
 
2002
Young Investigator Award: The 18th Annual Meeting of the Japanese Pharmacological Society
 
2002
Young Investigator Award for Japanese Fellow: The 56th Conference of the High Blood Pressure Council
 
2002
米国心臓学会/Young Investigator Award for Japanese Fellow
 
2004
Young Investigator Award/Japanese Society of Toxicology
 
2004
Young Investigator Award/ Vascular Biology Conference
 
2004
Vascular Biology Conference/ Young Investigator Award
 
2005
Young Investigator Award: The 5th Tokyo Aldosterone Forum
 
2005
Okamoto Research Award: Japan Vascular Disease Research Foundation
 
2006
The Harry Goldblatt Award Finalist
 

Published Papers

 
Diuretic effects of sodium glucose cotransporter 2 inhibitors and their influence on the renin-angiotensin system.
Ansary TM, Nakano D, Nishiyama A.
Int J Mol Sci.      2019   [Refereed]
Pathophysiological mechanisms of mineralocorticoid receptor-dependent cardiovascular and chronic kidney disease.
NISHIYAMA Akira
Hypertens Res.      2019   [Refereed]
(Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signaling pathway despite constitutive pathway component mutations.
Wang J. Shibayama Y, Zhang A, Ohsaki H, Asano E, Suzuki Y, Kushida Y, Kobara H, Masaki T, Wang Z, Nishiyama A.
Br J Cancer.   120(2) 229-237   2019   [Refereed]
Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone (CS-3150), on blood pressure and urinary angiotensinogen in low-renin Dahl salt-sensitive hypertensive rats.
Li L, Guan Y, Kobori H, Morishita A, Koboara H, Masaki T, Nakano D, Nishiyama A.
Hypertens Res.      2019   [Refereed]
Effect of the novel nonsteroidal selective mineralocorticoid receptor antagonist, esaxerenone (CS-3150), on blood pressure and renal injury in high salt-treated type 2 diabetic mice.
Bhuiyan SA, Rafiq K, Kobara H, Masaki T, Nakano D, Nishiyama A.
Hypertens Res.      2019   [Refereed]
Nrf2-related gene expression is impaired during a glucose challenge in type II diabetic rat hearts.
Thorwald MA, Godoy-Lugo JA, Rodriguez MA, Jamal M, Kinoshita H, Nakano D, Nishiyama A, Forman HJ, Ortiz RM.
Free Radic Biol Med.   130 306-317   2019   [Refereed]
The Japanese Society of Hypertension-Digest of plan for the future.
Node K, Kishi T, Tanaka A, Itoh H, Rakugi H, Ohya Y, Miura K, Okamura T, Ishimitsu T, Ichihara A, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nakamura S, Nishiyama A, Hasebe N, Higaki J, Tamura K, Kawano Y, Yatabe T, Ito S
Hypertens Res.   41(12) 989-990   Oct 2018   [Refereed]
Klotho protein supplementation reduces blood pressure and renal hypertrophy in db/db mice, a model of type2 diabetes.
Takenaka T, Kobori H, Miyazaki T, Suzuki H, Nishiyama A, Ishii N, Yamashita M, Hayashi M.
Acta Physiologica (Oxf).   e13190   Sep 2018   [Refereed]
A sodium-glucose cotransporter 2 inhibitor attenuates renal capillary injury and fibrosis by a vascular endothelial growth factor-dependent pathway after renal injury in mice.
Zhang Y, Nakano D, Guan Y, Hitomi H, Masaki T, Kobara H, Sugaya Y, Nishiyama A.
Kidney Int   94(3) 524-535   Sep 2018   [Refereed]
Combined therapy with gas gangrene antitoxin and recombinant human soluble thrombomodulin for clostridium perfringens sepsis in a rat model.
Hifumi T, Nakano D, Chiba J, Takahashi M, Yamamoto A, Fujisawa Y, Kuroda Y, Kawakita K, Nihsiyama A.
Toxicon.   141 112-117   Jan 2018   [Refereed]
Klotho ameliorates medullary fibrosis and pressure natriuresis in hypertensive rat kidneys.
Takenaka T, Inoue T, Miyazaki T, Kobori H, Nishiyama A, Ishii N, Hayashi M, Suzuki Hl.
Hypertension   72(5) 1151-1159   2018   [Refereed]
Tubular cell senescence in the donated kidney predicts allograft function, but not doner remnant kidney function, in living donor kidney transplantation.
Sofue T, Kushida Y, Ozaki T, Moritoki M, Nishijima Y, Ohsaki H, Ueda N, Kakehi Y, Nishiyama A, Minamino T.
Am J Nephrol.   47(1) 8-17   2018   [Refereed]
Gene expression changes in the retina after systemic administration of aldosterone.
Ono A, Hirooka K, Nakano Y, Nitta E, Nishiyama A, Tsujikawa A.
Jpn J Ophthalmol   62(4) 499-507   2018   [Refereed]
Ultrasonic standing wave preparation of a liquid cell for glucose measurements in urine by midinfrared spectroscopy and potential application to smart toilets.
Yamamoto N, Kawashima N, Kitazaki T, Mori K, Kang H, Nishiyama A, Wada K, Ishimaru I.
J Biomed Opt   23(5) 1-4   2018   [Refereed]
Thorwald M, Rodriguez R, Lee A, Martinez B, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM.
Redox Biol   14 371-378   2018   [Refereed]
Chronic AT1 blockade improves glucose homeostasis in obese OLETF rats.
Rodriguez R, Minas JN, Vazquez-Medina JP, Nakano D, Parkes DG, Nishiyama A, Ortiz RM.
J Endocrinol   237(3) 271-284   2018   [Refereed]
Add-on effect of angiotensin receptor blockade (candesartan) on clinical remission in active iga nephropathy patients treated with steroid pulse therapy and tonsillectomy: a randomized, parallel-group comparison trial
Kohagura K, Arima H, Miyasato H, Chang TH, Yamazato M, Kobori H, Nishiyama A, Iseki K, Ohya Y.
Kidney Blood Pressure Res   43 780-792   2018   [Refereed]
Effects of Olmesartan and Azilsartan on Albuminuria and the Intrarenal Renin-Angiotensin System.
Takami T, Okada S, Saito Y, Nishijima Y, Kobori H, Nishiyama A.
World J Res Rev.   6(1) 7-10   2018   [Refereed]
Angiotensin receptor and tumor necrosis factor-α activation contribute to glucose intolerance independent of systolic blood pressure in obese rats.
Rodriguez R, Lee A, Mathis KW, Broome HJ, Thorwald M, Martinez B, Nakano D, Nishiyama A, Ryan MJ, Ortiz RM.
Am J Physiol Renal Physiol   315(4) F1081-F1090   2018   [Refereed]
Guanylyl cyclase a in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.
Kitamura H, Nakano D, Sawanobori Y, Asaga T, Yokoi H, Yanagita M, Mukoyama M, Tokudome T, Kangawa K, Shirakami G, Nishiyama A.
Anesthesiology   129(2) 296-310   2018   [Refereed]
A novel approach to adenine-induced chronic kidney disease associated anemia in rodents.
Rahman A, Yamazaki D, Sufiun A, Kitada K, Hitomi H, Nakano D, Nishiyama A.
PLoS One   13(2) e0192531   2018   [Refereed]
Altered circadian timing system-mediated non-dipping pattern of blood pressure and associated cardiovascular disorders in metabolic and kidney diseases.
Rahman A, Hasan AU, Nishiyama A, Kobori H.
Int J Mol Sci.   19(2)    2018   [Refereed]
Effect of a SGLT2 inhibitor on the systemic and intrarenal renin-angiotensin system in subtotally nephrectomized rats.
Li L, Konishi Y, Morikawa T, Zhang Y, Kitabayashi C, Kobara H, Masaki T, Nakano D, Hitomi H, Kobori H, Nishiyama A.
J Pharmacol Sci   137(2) 220-223   2018   [Refereed]
Simultaneous GLP-1 receptor activation and angiotensin receptor blockade increase natriuresis independent of altered arterial pressure in obese OLETF rats.
Rodriguez R, Moreno M, Lee AY, Godoy-Lugo JA, Nakano D, Nishiyama A, Parkes D, Awayda MS, Ortiz RM.
Hypertens Res.   41(10) 798-808   2018   [Refereed]
Yamazaki D, Hitomi H, Nishiyama A.
Hypertens Res.   41(3) 147-156   2018   [Refereed]
The effects of sodium-glucose cotransporter 2 inhibitors on sympathetic nervous activity.
Wan N, Rahman A, Hitomi H, Nishiyama A.
Front Endocrinol   9 421   2018   [Refereed]
Independent regulation of renin-angiotensin-aldosterone system in the kidney.
Nishiyama A, Kobori H.
Clin Exp Nephrol.   22(6) 1231-1239   2018   [Refereed]
Effects of the selective chymase inhibitor, TEI-F00806, on intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice.
Ansary TM, Urushihara M, Fujisawa Y, Nagata S, Urata H, Nakano D, Hirofumi H, Kitamura K, Kagami S, Nishiyama A.
Exp Physiol.   103(11) 1524-1531   2018   [Refereed]
Involvement of complement 3 in the salt-sensitive hypertension by activation of renal renin-angiotensin system in spontaneously hypertensive rats.
Negishi E, Fukuda N, Otsuki T, Katakawa M, Komatsu K, Chen L, Tanaka S, Kobayashi H, Hatanaka Y, Ueno T, Endo M, Mashimo T, Nishiyama A, Abe M.
Am J Physiol Renal Physiol.   315(6) F1747-F1758   2018   [Refereed]
Cardiac Glutathione Levels Increase in Response to Glucose in Diabetic Rats.
Thorwald MA, Godoy-Lugo JA, Rodriguez GJ, Rodriguez MA, Jamal M, Kinoshita H, Nakano D, Nishiyama A, Forman HJ, Ortiz RM.
Free Radic Biol Med      2018   [Refereed]
(Pro)renin receptor is crucial for glioma development via the Wnt/β-catenin signaling pathway.
Kouchi M, Shibayama Y, Ogawa D, Miyake K, Nishiyama A, Tamiya T.
J Neurosurg.   127(4) 819-828   Oct 2017   [Refereed]
High glucose augments angiotensinogen in human renal proximal tubular cells through hepatocyte nuclear factor-5.
Wang J, Shibayama Y, Kobori H, Liu Y, Kobara H, Masaki T, Wang Z, Nihsiyama A.
PLoS ONE.   12(10) e0185600   Oct 2017   [Refereed]
Innovative delivery method using a detachable device to deliver a large polyglycolic acid sheet to a gastric ulcer perforation.
Mori H, Kobara H, Rahman A, Nishiyama N, Nishiyama A, Suzuki Y, Masaki T.
Endoscopy.   49(7) E165-E167   Jul 2017   [Refereed]
Klotho suppresses the renin-angiotensin system in adriamycin nephropathy.
Takenaka T, Inoue T, Miyazaki T, Kobori H, Nishiyama A, Ishii N, Hayashi M, Suzuk H.
Nephrol Dial Transpl   32(5) 791-800   May 2017   [Refereed]
Kobayashi R, Wakui H, Azushima K, Uneda K, Haku S, Ohki K, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Toya Y, Nishiyama A, Yamashita A, Tanabe K, Maeshima Y, Umemura S, Tamura K.
Kidney Int.   91(5) 1115-1125   May 2017   [Refereed]
High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
Kitada K, Daub S, Zhang Y, Klein JD, NAKANO Daisuke, Pedchenko T, ?Lantier L, LaRocque LM, Marton A, Neubert P, Schr?der A, Rakova N, Jantsch J, Dikalova AE, Dikalov Sl, Harrison DG, M?ller DN, NISHIYAMA Akira
J Clin Invest.   127(5) 1944-1959   May 2017   [Refereed]
Exogenous thyroxine improves glucose intolerance in insulin-resistant rats.
Vazquez-Anaya G, Martinez B, Soñanez-Organis JG, Nakano D, Nishiyama A, Ortiz RM.
J. Endocrinol.   232(3) 501-511   May 2017   [Refereed]
Hasan AU, Ohmori K, Hashimoto T, Kamitori K, Yamaguchi F, Noma T, Igarashi J, Tsuboi K, Tokuda M, Nishiyama A, Kohno M.
Biochem Biophys Res Commun.    486(1) 76-82   Apr 2017   [Refereed]
The Relationship Between the Renin-Angiotensin-Aldosterone System and NMDA Receptor-Mediated Signal and the Prevention of Retinal Ganglion Cell Death.
Kobayashi M, Hirooka K, Ono A, Nakano Y, Nishiyama A, Tsujikawa A.
Invest Ophthalmol Vis Sci.    8(3) 1397-1403   Mar 2017   [Refereed]
Miyashita T, Inamoto R, Fukuda S, Hoshikawa H, Hitomi H, Kiyomoto H, Nishiyama A, Mori N.
Auris Nasus Larynx   44(1) 52-57   Feb 2017   [Refereed]
Hasan AF, Ohmori Km Hashimoto T, Kamitori K, Yamaguchi F, Konishi K, Noma T, Igarashi J, Yamashita T, Hirano K, Tokuda M, Minamino T, Nishiyama A, Kohno M.
Biogerontol   18(1) 55-68   Feb 2017   [Refereed]
Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice.
Ishikawa S, Noma T, Fu H-Y, Matsuzaki T, Ishizawa M, Ishikawa K, Murakami K, Nishimoto N, Nishiyama A, Minamino T. 
PLoS One   12(11) e0187894   2017   [Refereed]
Responses of renal hemodynamics and tubular functions to acute sodium–glucose cotransporter 2 inhibitor administration in non-diabetic anesthetized rats.
Ansary T, Fujisawa Y, Rahman A, Nakano D, Hitomi H, Kobara H, Masaki T, Titze JM, Kitada K, Nishiyama A.
Sci Rep.   7(1) 9555   2017   [Refereed]
Guan Y, Nakano D, Zhang Y, Li L, Liu W, Nishida M, Kuwabara T, Morishita A, Hitomi H, Mori K, Mukoyama M, Masaki T, Hirano K, Nishiyama A. 
J. Pharmacol. Sci.   135(2) 81-88   2017   [Refereed]
Effects of sodium glucose cotransporter 2 inhibitors on urinary excretion of intact and total angiotensinogen in patients with type 2 diabetes.
Yoshimoto T, Furuki T, Kobori H, Miyakawa M, Imachi H, Murao K, Nishiyama A.
J Investing Med.   65(7) 1057-1061   2017   [Refereed]
Human pluripotent stem cell?derived erythropoietin-producing cells ameliorate renal anemia in mice
HITOMI Hirofumi, Kasahara T, Katagiri N, Hoshina A, Mae S, Kotaka M, Toyohara T, Rahman A, NAKANO Daisuke, Niwa A, Saito M, Nakata T, NISHIYAMA Akira
Sci Trans Med.   9(409) eaaj2300   2017   [Refereed]
Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice.?
Arai S, Kitada K, Mizuno M, Suzuki Y, Sakata F, NAKANO Daisuke, Tomita T, Hiramoto E, Takei Y, Maruyama S, NISHIYAMA Akira, Matsuo S
Arai S, Kitada K, Mizuno M, Suzuki Y, Sakata F, NAKANO Daisuke, Tomita T, Hiramoto E, Takei Y, Maruyama S, NISHIYAMA Akira, Matsuo S   7(1) 6450   2017   [Refereed]
Hasan AU, Kittikulsuth W, YAMAGUCHI Fuminori, Ansary TM, Rahman A, Shibayama Y, NAKANO Daisuke, HITOMI Hirofumi, NISHIYAMA Akira
Exp Cell Res.   358(2) 343-351   2017   [Refereed]
Effect of a selective SGLT2 inhibitor, luseogliflozin, on circadian rhythm of sympathetic nervous function and locomotor activities in metabolic syndrome rats.
Fujisawa Y, NAKANO Daisuke, Rahman A, HITOMI Hirofumi, NISHIYAMA Akira
Clin Exp Pharmacol Physiol.   44(4) 522-525   2017   [Refereed]
Uzu T, Araki SI, Kashiwagi A, Haneda M, Koya D, Yokoyama H, Kida Y, Ikebuchi M, Nakamura T, Nishimura M, Takahara N, Obata T, Omichi N, Sakamoto K, Shingu R, Taki H, Nagai Y, Tokuda H, Kitada M, Misawa M, Nishiyama A, Kobori H, Maegawa H, Shiga
PLoS ONE.   11(12) e0164936   2017   [Refereed]
Asadur R, Hitomi H, Nishiyama A
Hypertens Res.   40(6) 533-540   2017   [Refereed]
川嶋なつみ, 野郷孝介, 細野皐月, 西山成, 和田健司, 石丸伊知郎
Optical Engineering   55(11) 110506   Nov 2016   [Refereed]
Mizushige T, Kobori H, Hitomi H, Nishijima Y, Tomoda F, Morimoto S, Kohno M, Nishiyama A.
Int J Mol Sci.   17(11) E1800   Oct 2016   [Refereed]
Extensive pelagic spectroscopic measurement using an ultrasonically assisted unit based on a traveling wave
森敬太, 野郷孝介, 吉田光宏, Pradeep K.W.Abeygunawardhana, 鈴木聡, 西山 成?, 和田 健司, 石丸伊知郎
Proc. BISCp6-26 (September 2016), BISC’16 The 2nd Biomedical Imaging and Sensing Conference 2016   p6-26   Sep 2016   [Refereed]
Megalin-mediated tubulo-glomerular alterations in high-fat diet-induced kidney disease.
Kuwahara S, Hosojima M, Kaneko R, Aoki H, Nakano D, Sasagawa T, Kobasawa H, Kaseda H, Yasukawa R, Ishikawa I, Suzuki A, Sato H, Kageyama S, Tanaka T, Kitamura N, Narita I, Nishiyama A, Saito A.
J Am Soc Nephrol   27(7) 1996-2008   Jul 2016   [Refereed]
Takeshige Y, Fujisawa Y, Rahman A, Kittkulsuth W, NAKANO Daisuke, Mori H, MASAKI Tsutomu, OHMORI Koji, KOHNO Masakazu, Ogata H, NISHIYAMA Akira
Hypertens Res.   39(6) 415-422   Jun 2016   [Refereed]
Roksnoer LCW, Heijnen BFJ, Nakano D, Peti-Peterdi J, Walsh SB, Garrelds IM, van Gool JMG, Zietse R, Struijker-Boudier HAJ, Hoorn EJ、Dacser AH.
Hypertension   67(5) 927-933   May 2016   [Refereed]
Rahman A, Kittikulsuth W, Fujisawa Y, Sufiun A, Rafiq K, HITOMI Hirofumi, NAKANO Daisuke, Sohara E, Uchida S, NISHIYAMA Akira
J Hypertens.   34(5) 893-906   May 2016   [Refereed]
Husková Z, Kopkan L, Červenková L, Doleželová Š, Vaňourková Z, Škaroupková P, Nishiyama A, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Červenka L.
Clin Exp Pharmacol Physiol.   43(2) 438-449   Apr 2016   [Refereed]
Souma T, Nezu M, Nakano D, Yamazaki S, Hirano I, Sekine H, Dan T, Takeda K, Fong GH, Nishiyama A, Ito S, Miyata T, Yamamoto M, Suzuki N
J Am Soc Nephrol   27(2) 428-438   Feb 2016   [Refereed]
Sato S, Qi W, Kawashima N, Nogo K, Hosono S, Nishiyama A, Wada K,b and Ishimaru I.
Optical Engineering   55(2) 025106   Feb 2016   [Refereed]
野郷孝介, 和田健司, 西山成, 石丸伊知郎
Optical Review,   Vol.23(No.2) 360-363   Feb 2016   [Refereed]
Arai S, Kitada K, Yamazaki T, Takai R, Zhang X, Tsugawa Y, Sugisawa R, Matsumoto A, Mori M, Yoshihara Y, Doi K, Maehara N, Kusunoki S, Takahata A, Noiri E, Suzuki Y, Yahagi N, Nishiyama A, Gunaratnam L, Takano T, Miyazaki T.
Nat Med.   22(2) 183-193   Feb 2016   [Refereed]
野郷孝介, 和田健司, 西山成, 石丸伊知郎
Proc. of BiOS, Biomedical Optics Conference, part of SPIE Photonics West      Feb 2016   [Refereed]
Isobe S, Ohashi N, Ishigaki S, Tsuji T, Sakao Y, Kato A, Miyajima H, Fujigaki Y, Nishiyama A, Yasuda H.
Hypertens Res.   39(5) 312-320   2016   [Refereed]
NAKANO Daisuke, NISHIYAMA Akira
J Pharmacol Sci   132(1) 1-5   2016   [Refereed]
Devarajan S, Yahiro E, Uehara Y, Habe S, Nishiyama A, Miura S, Saku K, Urata H.
Am J Physiol Heart Circ Physiol   309(11) H1987-1996   Dec 2015   [Refereed]
Rafiq K, Fujisawa Y, Sherajee SJ, Rahman A, Sufiun A, KOBORI Hiroyuki, Koepsell H, Mogi M, Horiuchi M, NISHIYAMA Akira
Diabetologia.   58(12) 2885-2898   Dec 2015   [Refereed]
Nakano D, Doi K, Kitamura H, Kuwabara T, Mori K, Mukoyama M, Nishiyama A
J am Soc Nephrol.   26(12) 3035-3044   Dec 2015   [Refereed]
Kato S, Maruyama S, Makino H, Wada J, Ogawa D, Uzu T, Araki H, Koya D, Kanasaki K, Oiso Y, Goto M, NISHIYAMA Akira, KOBORI Hiroyuki, Imai E, Ando M, Matsuo S
Clin Exp Nephrol.   19(6) 1098-1106   Dec 2015   [Refereed]
Minas JN, Thorwald M, Conte D, V?zquez-Medina J-P, NISHIYAMA Akira, Ortiz RM
Clin Exp Pharmacol Physiol.   42(11) 1178-1188   Nov 2015   [Refereed]
Alánová P, Husková Z, Kopkan L, Sporková A, Jíchová Š, Neckář J, Imig JD, Klevstig M, Kolář F, Rami Reddy N, Falck JR, Sadowski J, Nishiyama A, Kramer HJ, Melenovský V, Červenková L, Kujal P, Vernerová Z, Červenka L.
Vascul Pharmacol.   73 44-56   Oct 2015   [Refereed]
Takenaka T, Inoue T, Miyazaki T, NISHIYAMA Akira, Ishii N, Hayashi M, Suzuki H
Am J Physiol Renal Physiol.   309(3) F216-226   Aug 2015   [Refereed]
Mizushige T, KOBORI Hiroyuki, NISHIJIMA Yoko, Yano Y, Sakata K, Hayakawa M, NISHIYAMA Akira
J Diabetes Res.      Aug 2015   [Refereed]
Červenka L, Melenovský V, Husková Z, Škaroupková P, Nishiyama A, Sadowski J.
Clin Exp Pharmacol Physio.   42(7) 795-807   Jul 2015   [Refereed]
Qi W, Suzuki Y, Sato S, Fujiwara M, Kawashima N, Suzuki S, Abeygunawardhana P, Wada K, Nishiyama A, Ishimaru I.
Applied Optics   54(20) 6254-6259   Jul 2015   [Refereed]
Morita T, NAKANO Daisuke, Kitada K, Morimoto S, Ichihara A, HITOMI Hirofumi, KOBORI Hiroyuki, Shiojima I, NISHIYAMA Akira
European J Pharmacol.   756 85-91   Jun 2015   [Refereed]
細野皐月, 和田健司, 西山成, 石丸伊知郎
Clinical and Biomedical Spectroscopy and Imaging IV, Proc. of SPIE-OSA   Vol. 9537, 953715    Jun 2015   [Refereed]
藤原大, 和田健司, 西山成, 石丸伊知郎
Clinical and Biomedical Spectroscopy and Imaging IV, Proc. of SPIE-OSA   Vol. 9537, 953714    Jun 2015   [Refereed]
Zhou MS, Liu C, Tian R, NISHIYAMA Akira, Raij L
Cardiovasc Diabetol.   14(1) 45   May 2015   [Refereed]
Okabe M, Miyazaki Y, Niimura F, Pastan I, NISHIYAMA Akira, Yokoo T, Ichikawa I, Matsusaka T
Am J Physiol Renal Physiol.   308(8) F932-937   Apr 2015   [Refereed]
Palm-Size Ultra-Compact Wide-Field Fourier Spectroscopic Imaging Technology
鈴木 陽、斉 威、佐藤 駿、藤原 大、平松裕行、川嶋なつみ、鈴木 聡、Abeygunawardhana、和田健司、西山 成、小林宏明、石丸伊知郎
43(3) 222-226   Apr 2015   [Refereed]
Proposal of ultrasonic-assisted spectroscopy for practical usages
野郷孝介, 和田健司, 西山成, 石丸伊知郎
OPTICS & PHOTONICS International 2016 Congress   APBP5-4    Apr 2015   [Refereed]
Ono M, Sakao Y, Tsuji T, Ohashi N, Yasuda H, NISHIYAMA Akira, Fujigaki Y, Kato A
Clin Exp Nephrol.   19(2) 185-196   Apr 2015   [Refereed]
Proposal of Raman Fourier-spectroscopic tomography for iPS solid organs in the field of regenerative medicine
小川哲, 和田健司, 西山成, 石丸伊知郎
Proc. of OPTICS & PHOTONICS International 2016 Congress   APBPp2-3    Apr 2015   [Refereed]
Proc. of OPTICS & PHOTONICS International 2016 Congress
森敬太, 和田健司, 西山成, 石丸伊知郎
森敬太, 和田健司, 西山成, 石丸伊知郎   APBP5-5    Apr 2015   [Refereed]
Sufiun A, Rafiq K, Fujisawa Y, Rahman A, Mori H, Nakano D, Kobori H, Ohmori K, Masaki T, Kohno M, Nishiyama A.
Hypertens Res   38(4) 237-243   Apr 2015   [Refereed]
Shibayama Y, Fujimori T, Nguyen G, Hirose T, Totsune K, Ichihara A, Kitada K, Nakano D, Kobori H, Kohno M, Masaki T, Suzuki Y, Yachida S, Nishiyama A.
Sci Rep.   5 8854   Mar 2015   [Refereed]
SOFUE Tadashi, INUI Masashi, HARA Taiga, MORITOKI Masahiro, NISHIJIMA Yoko, KUSHIDA Yoshio, NISHIYAMA Akira, KAKEHI Yoshiyuki, KOHNO Masakazu
Transplant Proc.   47(2) 332-336   Mar 2015   [Refereed]
Renal tubule angiotensin II type 1 receptor-associated protein promotes natriuresis andinhibits salt-sensitive blood pressure elevation.
Wakui H, Uneda K, Tamura K, Ohsawa M, Azushima K, Kobayashi R, Ohki K, Dejima T, Kanaoka T, Tsurumi-Ikeya Y, Matsuda M, Haruhara K, Nishiyama A, Yabana M, Fujikawa T, Yamashita A, Umemura S. 
J Am Heart Assoc   4(3) e001597   Mar 2015   [Refereed]
Proposal of AAA-battery-size one-shot ATR Fourier spectroscopic imager for on-site analysis
細野皐, 和田健司, 西山成, 石丸伊知郎
Proc. of BiOS, Biomedical Optics Conference, part of SPIE Photonics West      Feb 2015   [Refereed]
川嶋なつみ, 西山成, 和田健司, 石丸伊知郎
Proc. of BiOS, Biomedical Optics Conference, part of SPIE Photonics West      Feb 2015   [Refereed]
石丸伊知郎, 和田健司, 西山成
Proc. of BiOS, Biomedical Optics Conference, part of SPIE Photonics West      Feb 2015   [Refereed]
Souma T, Nezu M, NAKANO Daisuke, Yamazaki S, Hirano I, Sekine H, Dan T, Takeda K, Fong GH, NISHIYAMA Akira, Ito S, Miyata T, Yamamoto M, Suzuki N
J Am Soc Nephrol .      2015   [Refereed]
Sporkova A, Jichova S, Huskova Z, Kopkan L, NISHIYAMA Akira, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L
Clin Exp Pharmacol Physiol.   41(12) 1003-1013   Dec 2014   [Refereed]
NISHIJIMA Yoko, KOBORI Hiroyuki, KAIFU Kumiko, MIZUSHIGE Tomoko, HARA Taiga, NISHIYAMA Akira, KOHNO Masakazu
J Renin Angiotensin Aldosterone Syst.   15(4) 505-508   Dec 2014   [Refereed]
WIDE-FIELD INFRARED SPECTROSCOPIC IMAGING FOR NON-DESTRUCTIVE COMPONENT ANALYSIS
藤原大, 和田健司, 西山成, 石丸伊知郎
World FORENSIC FESTIVAL 2014 Abstract Book,   P 03-21,   Oct 2014   [Refereed]
Kitada K, NAKANO Daisuke, Ohsaki H, HITOMI Hirofumi, Minamino T, yatabe J, Felder RA, Mori H, MASAKI Tsutomu, KOBORI Hiroyuki, NISHIYAMA Akira
J Diabetes Complicat   28(5) 604-611   Oct 2014   [Refereed]
Ohsawa M, Tamura K, Wakui H, Maeda A, Dejima T, Kanaoka T, Azushima K, Uneda K, Tsurumi-Ikeya Y, Kobayashi R, Matsuda M, Uchida S, Toya Y, KOBORI Hiroyuki, NISHIYAMA Akira, Yamashita A, Ishikawa Y, Umemura S
Kidney Int.   86(3) 570-581   Sep 2014   [Refereed]
Rafiq K, NISHIYAMA Akira, Konishi Y, Morikawa T, Kitabayashi C, KOHNO Masakazu, MASAKI Tsutomu, Mori H, KOBORI Hiroyuki, Imanishi M
PLoS ONE   9(9) e107853   Sep 2014   [Refereed]

Misc

 
The Sendai declaration for the eradication of kidney disease.
Kashihara N, Nangaku M, Ito S, Nishiyama A, Harris D.
Clin Exp Nephrol.   22(1) 1-2   2018
A novel role of renin inhibitor in the complement cascade.
Nakano D, Nishiyama A.
Kidney Int.   94(4) 650-652   2018
Commentary for Aliskiren inhibits renin-mediated complement activation.
Nakano D, Nishiyama A.
Kidney Int.      2018
How should we treat patients with primary aldosteronism to prevent new-onset diabetes mellitus?
Hitomi H, Nishiyama A.
J Hypertens.   35(8) 1575-1576   2017
Sodium intake affects gender difference in aldosterone concentration.
Kitada K, Nishiyama A.
Am J Physiol Renal Physiol.   313(4) F957-F958   2017
Pathophysiology of renal injury in salt-sensitive hypertension
NISHIYAMA,Akira
薬学研究症例財団研究報告集   61-67   2005
Role of aldosterone in the kidney
NISHIYAMA,Akira, ABE,Youichi
Hypertension Frontier.   (8) 47-59   2005
Abnormal renal microcirculation in type II diabetic nephropathy: role of angiotensin II and oxidative stress
NISHIYAMA,Akira
第35回三井生命科学研究財団研究報告集   41-44   2004
Study for the role of oxidative stress in renal failure and hemodialysis
HIGASHIYAMA,Chikako, KIYOMOTO,Hideyasu, NISHIYAMA,Akira, IMANISHI,Masahito, KOHNO,Masakaz
腎臓   (27) 105-109   2004
Contribution of redox-sesitive MAP kinase to the progression of renal injury in Dahl salt-sensitive hypertensive rats.
NISHIYAMA,Akira
腎とフリーラジカル   (7) 30-34   2004
Minerarocorticoid receptor and its antagonists
NISHIYAMA,Akira, ABE,Youichi
ホルモンと臨床   (52) 777-785   2004
Renal injury and aldosterone
NISHIYAMA,Akira, ABE,Youichi
日薬理誌   (124) 101-109   2004

Books etc

 
Kidney and blood pressure regulation.
Karger   2004   
Kidney and blood pressure regulation./Renal renin-angiotensin system.
Karger   2004   
Oxidative stress in applied bascic research and clinical practice. Studies on Renal Disorders. /Renin-angiotensin system in the kidney and oxidative stress s: Local renin-angiotensin-aldosterone system and NADPH
Humana Press.   2011   
Chapter 4: Renin-angiotensin system in the kidney and oxidative stress: Local renin-angiotensin-aldosterone system and NADPH oxidase-dependent oxidative stress in the kidney. In: Miyata T, Eckardt K-U, Nangaku M, ed. Studies on renal disorders, oxidati・・・
2011   
Chapter 4: Renin-angiotensin system in the kidney and oxidative stress: Local renin-angiotensin-aldosterone system and NADPH oxidase-dependent oxidative stress in the kidney. In: Miyata T, Eckardt K-U, Nangaku M, ed. Studies on renal disorders, ox...

Conference Activities & Talks

 
Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone(CS-3150),on blood pressure and urinary angiotensinogen in low-renin dahl satl-sensitive hypertensive rats.
Nishiyama A, Nakako D, Kobori H, Li L.
ISN WCN2019   Apr 2019   
(Pro)renin Receptor Promotes Colorectal Cancer through the Wnt/Beta-Catenin Signaling Pathway despite Constitutive Pathway Component Mutations.
Nishiyama A, Shibayama Y, Wang J.
AHA Joint Hypertension 2018   Sep 2018   
High Salt Intake Induces Catabolism Accompanied By Hepatic Urea Osmolyte Production And Decreases Renal Sympathetic Nerve Activity
Morisawa N, Kitada K, Yamazaki D, Nakano D, Fujisawa Y, Nishiyama A.
AHA Joint Hypertension 2018   Sep 2018   
Intravital microscopy.
Nishiyama A.
16th APCN & 2018 Annual Congress of Chinese Society of Nephrology   Mar 2018   
Loss of Urine Concentration and Subsequent Dehydration Characterizes Hypertension in Rats with Chronic Renal Failure.
Johannes K, Kitada K, Marton A, Daub S, Morisawa N, Zhang Y, Pedchenko T, Zhao Y, Klein JD, Bailey JL, Cordasic N, Hilgers KF, Sands JM, Nishiyama A.
Gordon Research Conference   Feb 2018   
Podocyte Injury Enhances Intrarenal Angiotensin II Generation and Sodium Retention Dependently on Megalin.
Koizumi M, Niimura F, Nishiyama A, Yanagita M, Fukagawa M, Matsusaka T.
Gordon Research Conference   Feb 2018   
Melanocortin 3 Receptor Deletion Induces Skin-Specific Na+ and Water Loss that Cannot Be Compensated by Glucocorticoid-Driven Urea Osmolyte Generation and Accumulation.
Kitada K, Klein JD, Nisiyama A, Luft FC, Sands JM, Titze J
Gordon Research Conference   Feb 2018   
Role of (pro)renin receptor in the pathophysiology of cancer.
Nishiyama A, Shibayama Y.
Gordon Research Conference   Feb 2018   
Treatment with the SGLT2 Inhibitor Luseogliflozin after Ischemia/Reperfusion Attenuated Renal Fibrosis through Reversing the Endothelial Rarefaction in Mice.
Nakano D, Nishiyama A.
KIDNEY WEEK 2017   Nov 2017   
Aberration of (pro)renin receptor induces genomic instablity in human pancreatic ductal epithelial cells
Shibayama Y, Yasuda J, Yamazaki D, Rahman A, Yachida S, Nishiyama A.
AACR Annual Meeting 2017   Apr 2017   
Esaxerenone (CS-3150), a non-steroidal selective mineralocorticoid receptor antagonist, elicits renoprotective effects in high salt-treated type 2 diabetic KKAy mice
Nishiyama A, Hitomi H, Nakano D.
ISN WCN2017   Apr 2017   
Hepatocyte nuclear factor -5 acts as a glucose-responsive element of human angiotensinogen promoter.
Wang J, Kobori H, Shibayama Y, Nakano D, Hitomi H, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Role of (pro) renin receptor in the activation of wnt/ β-catenin pathway in colon cancer.
Wang J, Shibayama Y, Nakano D, Hitomi H, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
The activated intrarenal renin-angiotensin systems and oxidative stress in tubular can be the original mechanism of renal damage in primary aldosteronism.
Iwakura Y, Morimoto R, Kikuchi K, Ono Y, Tezuka Y, Tsukada Y, Nezu M, Igarashi Y, Kudo M, Nishiyama A, Ito S, Satoh F.
26th Meeting of the International Society of Hypertension   Sep 2016   
Dipping pattern of blood pressure and renal injury in Dahl salt-sensitive hypertensive rats.
Nishiyama A, Sufiun A, Fujisawa Y, Rahman A, Nakano D, Hitomi H.
26th Meeting of the International Society of Hypertension   Sep 2016   
Atrial natriuretic peptide improves urine flow at proximal tubules in septic acute kidney injury.
Kitamura H, Nakano D, Yifan Z, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Effects of SGLT2 inhibitors on circadian rhythm of blood pressure in rats.
Rahman A, Takeshige Y, Fujisawa Y, Hitomi H, Nakano D, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Mouse glomerular injury reduced by blocking n-type calcium channel.
Guan Y, Nakano D, Yifan Z, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Role of hepatocyte nuclear factor-5 in high glucose-induced augmentation of proximal tubular angiotensinogen.
Nishiyama A, Kobori H, Shibayama Y, Wang J
53th ERA-EDTA Congress   May 2016   
Intravital imaging of oxidative stress in renal proximal tubules.
Nishiyama A, Nakano D
The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide   May 2016   
A sodium-glucose co-transporter 2 inhibitor prevents abnormality of circadian rhythm of blood pressure in salt-treated obese rats.
Nishiyama A, Nakano D, Ogata H, Takeshige Y
American Heart Association Scientific Session   Oct 2015   
Cell cycle progression in the early phase of septic kidney
Nakano D, Nishiyama A
American Society of Nephrology   Oct 2015   
Effects of diuretics on SGLT2 inhibitor-induced changes in blood pressure and natriuresis in obese rats suffering from the metabolic syndrome.
Rahman A, Kittikulsuth W, Fujisawa Y, Hitomi H, Nakano D, Sohara E, Uchida S, Nishiyama A
American Society of Nephrology   Oct 2015   
Changes in dipping pattern of blood pressure during the progression of renal injury in Dahl salt-sensitive hypertensive rats.
Sufiun A, Fujisawa Y, Rahman A, Nakano D, Hitomi H, Nishiyama A
American Heart Association High Blood Pressure Council   Sep 2015   
Role of (Pro)renin receptor in the pathogenesis of colon cancer.
Nishiyama A, Wang J, Yachida S, Nguyen G, Hirose T, Shibayama Y
American Heart Association High Blood Pressure Council   Sep 2015   
Remote ischemic preconditioning of hind-limb in anesthetized mice did not protect kidney from ischemia/reperfusion injury
第58回日本腎臓学会学術総会   Jun 2015   
Mouse podocytes injury is reduced by bloking N-type calcium channel.
第58回日本腎臓学会学術総会   Jun 2015   
Effect of intravenous administration of a SGLT2 inhibitor on renal hemodynamics and functions in anesthetized rats.
第58回日本腎臓学会学術総会   Jun 2015   
Effect of diuretics on SGLT2 inhibitor-induced changes in blood pressure and renal function in obese metabolic syndrome rats.
第58回日本腎臓学会学術総会   Jun 2015   
SGLT2 inhibitor, empagliflozin, decreases blood pressure through an increase in urinary excretion of sodium in salt-treated obese OLETF rats.
Takeshige Y, Fujisawa Y, Rahman A, Nakano D, Ogata H, Nishiyama A
World Congress of Nephrology   Mar 2015   
Effect of vildagliptin, a dpp-4 specific inhibitor, on blood pressure and its circadian dipping pattern during the development of salt-dependent hypertension in Dahl salt-sensitive rats.
Sufiun A, Rafiq K, Nishiyama A
World Congress of Nephrology   Mar 2015   
Reduction of Tubular Flow Rate as a Mechanism of Oliguria in Endotoxemia Revealed by Intravital Imaging
Nakano D, Doi K, Kuwabara T, Mori K, Masashi Mukoyama M, Nishiyama A
American Society of Nepjrology, Kidney week 2014   Nov 2014   
DDP-4阻害薬は食塩感受性高血圧ラットにおいて尿中Na排泄増加を伴ったdipping patternの改善と降圧作用を示す
第44回日本腎臓学会東部学術大会   Oct 2014   
SGLT2阻害薬エンパグリフロジンは、ナトリウム利尿を介してdippingパターンの正常化を伴った降圧を示す
第44回日本腎臓学会東部学術大会   Oct 2014   
SGLT2阻害薬によるナトリウム利尿作用は、利尿薬の併用によって影響を受けない
第44回日本腎臓学会西部学術大会   Oct 2014   
肥満ラットのインスリン抵抗性は、腎交感神経切除によってSGLT-2発現減少を介して改善する
第44回日本腎臓学会西部学術大会   Oct 2014   
CKDにおける腎内局所レニン・アンジオテンシン系の役割
第44回日本腎臓学会西部学術大会   Oct 2014   
アンジオテンシンⅡによるポドサイト内カルシウム濃度上昇には、N型カルシウムチャネルが必須である
第44回日本腎臓学会東部学術大会   Oct 2014   
Effects of Diuretics on Sglt2 Inhibitor-induced Changes in Urinary Sodium Excretion Rate In Obese Metabolic Syndrome Rats.
Nishiyama A, Fujisawa Y, Sufiun A, Rafiq K, Nakano D, Kobori H, Rahman A
High Blood Pressure Research   Sep 2014   
Effect of Dipeptidyl Peptidase-4 Inhibition on Blood Pressure and its Dipping Pattern in Dahl Salt-Sensitive Rats.
Nishiyama A, Fujisawa Y, Rahman A, Nakano D, Rafiq K, Kobori H, Sufiun A
High Blood Pressure Research   Sep 2014   
Role of the renal sympathetic nerve in renal glucose metabolism during the development of type 2 diabetes in rats.
Rafiq K, Fujisawa Y, Nishiyama A
ISN NEXUS Symposium Hypertension and Kidney   Sep 2014   
Effect of diuretics on SGLT2 inhibitor-induced natriuresis in obese metabolic syndrome rats.
Rahman A, Nishiyama A
ISN NEXUS Symposium Hypertension and Kidney   Sep 2014   
Effects of the SGLT2 inhibitor, empagliflozin, on blood pressure and its circadian pattern in salt-treated obese rats.
Takeshige Y, Nishiyama A.
ISN NEXUS Symposium Hypertension and Kidney   Sep 2014   
Renal sympathetic denervation improves glucose metabolism through an activation of sodium dependent glucose transporter 2 in type 2 diabetic rats.
Nishiyama A, Fujisawa Y, Rahman A, Mogi M, Sufiun A, Rafiq K
International Society of Hypertension   Jun 2014   
Effects of vildagliptin on blood pressure and dipping pattern in Dahl salt-sensitive rats.
Nishiyama A, Fujisawa Y, Rahman A, Nakano D, Kobori H, Rafiq K, Sufiun A
International Society of Hypertension   Jun 2014   
Circadian rhythm of angiotensinogen levels in the plasma and urine of patients with chronic kidney disease.
Nishijima Y, Kobori H, Mizushige T, Hara T, Kohno M, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effect of a direct renin inhibitor on blood pressure and renin-angiotensin system in a patient with renovascular hypertension.
Kishida M, Nishiyama A, Hamada M, Shibata M, Kitabayashi C, Morikawa T, Konishi Y, Arai Y, Ichihara A, Kobori H, Imanishi M
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effects of a SGLT2 inhibitor empagliflozin, on blood pressure and urinary excretion of sodium in salt-treated metabolic syndrome rats.
Takeshige Y, Fujisawa Y, Sufiun A, Rahman A, Rafiq K, Nakano D, Ogata H
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effects of renal sympathetic denervation on blood pressure and glucose metabolism in obese type 2 diabetic rats.
Rafiq K, Sherajee S, Fujisawa Y, Mogi M, Sufiun A, Rahman A, Nakano D, Koepsell H, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
The efficacy and safety of febuxostat in the treatment of post-transplant hyperuricemia in stable kidney transplant recipients.
Sofue T, inui M, Hara T, Nishijima Y, Moriwaki K, Hayashida Y, Ueda N, Nishiyama A, kakehi Y, Kohno M
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effects of alogliptin on urinary excretion rates of albumin and angiotensinogen in patients with type 2 diabetes.
Mizushige T, Kobori H, Nishijima Y, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effects of high salt and renal denervation on blood pressure and dipping pattern in rats treated with adenine.
Sufiun A, Rahman A, Kitada K, Fujisawa Y, Nakano D, Rafiq K, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effects of erythropoietin originated by human ips cell-derived erythropoietin producing cells on adenine-induced renal anemia in mice.
Rahman M, Hitomi H, Osafune K, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effect of vildagliptin, a dpp-4 inhibitor, on blood pressure and dippiping pattern in dahl salt-sensitive rats.
Sufiun A, Fujisawa Y, Rahman A, Nakano D, Rafiq K, Kobori H, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Renal sympathetic denervation suppresses insulin resistance in pre-diabetic obese oletf rats.
Rafiq K, Sherajee S, Fujisawa Y, Mogi M, Rahman A, Sufiun A, Nakano D, Koepsell H, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Multiphoton imaging of microcirculation in the septic kidney.
Nakano D, Nishiyama A
The 18th International Vascular Biology Meeting   Apr 2014   
Pharmacological Impacts of GLP-1 Analogues and DPP-4 Inhibitors on Their Cardiovascular Protective Effects
8th International Congress on Uremia Research and Toxicity   Mar 2014   
Extra-renal effect of RAAS Blockade
8th International Congress on Uremia Research and Toxicity   Mar 2014   
(Pro)renin receptor is crucial for Wnt/β-cathenin-dependent genesis of pancreatic ductal adenocarcinoma.
Nishiyama A, Shibayama Y
Gordon Research Conference, The renin-Angiotensin System Beyond Angiotensin II   Mar 2014   
Suppression of insulin resistance by renal sympathetic denervation in obese rats.
Rafiq K, Fujisawa Y, Rahman  A, Sufiun A, Nakano N, Nishiyama A
Annual Meetings of the American Society of Nephrology   Nov 2013   
Incretin Hormones in CVD; Overview
American Heart Association Scientific Session.   Nov 2013   
Angiotensin Receptor Activation Contributes to Glucose Intolerance and Increased Insulin Resistance Independent of Elevated Systolic Blood Pressure, Adiposity and Dyslipidemia in a Model of Metabolic Syndrome
Lee AY, Rodriguez RR, Martinez B, Nakano D, Nishiyama A, Ortiz R
High Blood Pressure Research   Sep 2013   
Combined Treatment With Irbesartan and Vitamin D Retards Renal Injury in Salt-loaded Uni-nephrectomized Stroke-prone Spontaneously Hypertensive Rats
Takenaka T, Inoue T, Ohno Y, Miyazaki T, Nishiyama A, Ishii N, Suzuki H
High Blood Pressure Research   Sep 2013   
AngiotensinⅡPromotes Proliferation and Fibrosis in Parietal Epithelial Cells Contributing to the Development of Crescentic Glomerulonephritis
Shibayama Y, Urushihara M, Nishiyama A, Kobori H
High Blood Pressure Research   Sep 2013   
Renin Rebox? Intrarenal vs Systemic Angiotensin Regulation.
High Blood Pressure Research   Sep 2013   
Renal sympahtetic denervation at a prediabetic stage suppresses insulin resisitance in obese rats.
第61回日本心臓病学会学術集会   Sep 2013   
Renal sympathetic denervation at a prediabetic stage suppresses insulin resistance in OLETF rats
第49 回高血圧関連疾患モデル学会学術総会   Sep 2013   
Endothelial Cell-Derived ET--1 Contributes to the Severity of Septic Kidney Injury
Nakano D, Emoto N, Nakayama K, Yanagisawa M, Nishiyama A
International Conference on Endothelin   Sep 2013   
Urinary Angiotensinogen Could be a Prognostic Marker of Renoprotective Effects of Alogliptin in Patients with Type 2 Diabetes
Mizushige T, Kobori H, Nishijima Y, Yano Y, Sakata K, Hayakawa M, Nishiyama A
High Blood Pressure Research   Sep 2013   
Circadian Rhythm of Plasma and Urinary Angiotensinogen in Patients with Chronic Kidney Disease
Nishijima Y, Kobori H, Mizushige T, Hara T, Nishiyama A, Kohno M
High Blood Pressure Research   Sep 2013   
P21 is Essential for the Beneficical Effects of Renal Ischemic Preconditioning in Ischemic Acute Kidney Injury
Nishioka S, Nakano D, Kitada K, Ohsaki H, Sofue T, Kohno M, Nishiyama A
High Blood Pressure Research   Sep 2013   
An Iron Chelator, Deferasirox, Prevents Renal Iron Accumulation and Macrophage Infiltration But Not Cell Senescence in Type 1 Diabetic Mice
Nakano D, Morita T, Kitada K, Nishiyama A
High Blood Pressure Research   Sep 2013   
Angiotensin Receptor Blockade Ameliorates the Hypertension Associated with Acute Glucagon-like Peptide-1 Receptor Activation
Rodriguez R, Lee A, Moreno M, Vazquez G, Ruilova SD, Nishiyama A, Ortiz RM
High Blood Pressure Research   Sep 2013   
Azelnidipine enhances protective effects of olmesartan against bbb and renal injuries in type 2 diabetic mice, independent of blood pressure changes
Rafiq K, Nishiyama A
World Congress of Nephrology   May 2013   
Renal iron accumulation in type 1 diabetic mice is independent of cell senescence
Morita T, Nakano D, Kitada K, Nishiyama A
World Congress of Nephrology   May 2013   
Effects of olmesartan on albuminuria and urinary angiotensinogen excretion in patients with metabolic syndrome
Hitomi H, Kobori H, Nishiyama A
World Congress of Nephrology   May 2013   
Effects of erythropoietin producing cell-derived erythropoietin from human iPS cell on anemia.
第2回神経研究EXPO   Mar 2013   
Sympathetic renal denervation suppresses insulin resistance in type 2 diabetic rats.
第2回神経研究EXPO   Mar 2013   
Effect of high salt on blood pressure in adenine-induced renal injury in rats
第42回日本心脈管作動物質学会   Feb 2013   
Renal sympahtetic denervation improves insulin resisitance in obese rats.
第17回日本心血管内分泌代謝学会   2013   
Angiotensin Receptor Activation Contributes to Glucose Intolerance and Increased Insulin Resistance Independent of Elevated Systolic Blood Pressure Adiposity and Dyslipidema in a Model of Metabolic Syndrome
High Blood Pressure Research   2013   
Combind Treatment With Irbesartan and Vitamin D Retards Renal Injury in Salt-loaded Uni-nephrectomized Stroke-prone Spontaneously Hypertensive Rats
High Blood Pressure Research   2013   
(P)RR and pancreatic cancer
German Hypertension Society Dec   2012   
Identification of glucose-responsive elements in promoter regions of human angiotensinogen gene
第122回日本薬理学会近畿部会   2012   
Novel mechanisms of aldosterone mediated vascular injury: The forgotten A in the RAAS.
Annual Meetings of the American Society of Nephrology   2012   
Roles of Na+/H+ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis.
Annual Meetings of the American Society of Nephrology   2012   
Liver-, but not kidney-specific angiotensinogen gene knockout abrogates the enhancement of renal angiotensin Ⅱ synthesis that follows podocyte injury in progressive glomerulosclerosis.
Annual Meetings of the American Society of Nephrology   2012   
Renal sympathetic deneravation suppresses de novo albuminuria in rats with aortic regurgitation
24th Scientific Meeting of the International Society of Hypertension   2012   
Oxidative stress-induced glomerular mineralocorticoid recepter activation limits the benefit of salt reduction in Dahl salt-sensitive hypertensive rats.
24th Scientific Meeting of the International Society of Hypertension   2012   
Does iron cause cell senescence and renal inflammation in diabetic mouse model?
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   2012   
Roles of NHE-1 and intracellular pH in Angiotensin II-induced reactive oxygen species generation and podocyte apoptosis
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   2012   
Adenine induced renal injury with severe anemia in rat and mice
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   2012   
Effect of high salt on blood pressure in adenine-induced renal injury in rats
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   2012   
Restoration of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of olmesartan and azelnidipine in dahl salt-sensitive rats
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   2012   
Azelnidipine enhances protective effects of olmesartan against BBB and renal injuries in type 2 diabetic mice
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   2012   
p21 plays a protective role against renal ischemia reperfusion injury and is an essential factor for ischemic preconditioning
High Blood Pressure Research   2012   
Specified Proximal Tubule Segments Augmented Angiotensinogen mRNA and Protein Expressions in Diabetic Kidney in Rats and Humans
High Blood Pressure Research   2012   
The circadian rhythm of plasma angiotensinogen in healthy volunteers
High Blood Pressure Research   2012   
Aldosterone Evokes senescence-associated secreting phenotype and subsequent apoptsis in proximal tubular cells
High Blood Pressure Research   2012   
Telmisartan but not tempol improves the already established renal cell senescence in type 2 diabetic rats
High Blood Pressure Research   2012   

Works

 
Joint Research on the role of intrarenal renin-angiotensin-aldosterone system in the development of diabetic nephropathy
2002
Joint Research on the regulation of intrarenal renin-angiotensin-aldosterone system and its role in the development of hypertension and renal injury.
2002
Joint Research on the regulation of renal microcirculation.
2002
Joint Research on Mechanism of the development of nephropathy during salt-induced hypertension
2001

Research Grants & Projects

 
Study on the mechanism of the development of hypertension
Study on diabetic nephropathy
Study on the regulation of renal hemodynamics
ATP-dependent regulation of tubuloglomerular feedback (TGF) mechanism in hypertensive rats.
Role of symapthetic nerve activity in the development of hypertension.
Independent regulation of intrarenal renin-angiotensin-aldosterone system.
Role of angiotensin II (Ang II), aldosterone and mechanical force in reactive oxygen species (ROS) production.