KANDA Atsuhiro

J-GLOBAL         Last updated: Jun 21, 2019 at 07:51
 
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Name
KANDA Atsuhiro
Affiliation
Hokkaido University
Section
Graduate School of Medicine
Job title
Researcher
Degree
Ph.D. (D.Pharm)(Setsunan University), B.Sc.(Setsunan University), Ph.D. (Med.Sc.D)(Hokkaido University)
Research funding number
80342707

Research Areas

 
 

Academic & Professional Experience

 
2010
 - 
Today
Hokkaido University
 
2008
 - 
2010
Research fellow, National Eye Institutes
 
2005
 - 
2008
Post-doc fellow, University of Michigan
 
2000
 - 
2001
Researcher, Nagaoka Perfumery Corporation, Technology Research and Development Center
 
2001
   
 
Research Assistant, JSPS, Genome project
 

Education

 
 
 - 
2000
Graduate School, Division of Pharmaceutical Sciences, Setsunan University
 

Awards & Honors

 
2018
Cosmo Bio Award
 
2017
The Japanese Society of Anti-aging Medicine Best Presentation Award
 
2017
The Japan Society of DiabeticComplications Young Investigator Award
 
2017
Bayer Retina Award
 
2017
Global Ophthalmology Awards Program (GOAP) Research Award, Bayer
 

Published Papers

 
Galectin-1 promotes choroidal neovascularization and subretinal fibrosis mediated via epithelial-mesenchymal transition
Di W, Kanda A, Ye L, Kase S, Noda, K, Ishida S.
FASEB J      Feb 2019   [Refereed]
Yoshida S, Murata M, Noda K, Matsuda T, Saito M, Saito W, Kanda A, Ishida S
Japanese journal of ophthalmology      Feb 2018   [Refereed]
Clinical features of Japanese patients with anti-α-enolase antibody-positive autoimmune retinopathy: Novel subtype of multiple drusen.
Ando R, Saito W, Kanda A, Kase S, Fujinami K, Sugahara M, Nakamura Y, Eguchi S, Mori S, Noda K, Shinoda K, Ishida S
Am J Ophthalmol.      2018   [Refereed]
Kanda A, Dong Y, Noda K, Saito W, Ishida S
Scientific reports   7(1) 16168   Nov 2017   [Refereed]
Murata M, Noda K, Kawasaki A, Yoshida S, Dong Y, Saito M, Dong Z, Ando R, Mori S, Saito W, Kanda A, Ishida S
Current eye research   42(12) 1-10   Sep 2017   [Refereed]
Kinoshita S, Ohguchi T, Noda K, Murata M, Yasueda SI, Obata H, Matsunaga T, Fukushima T, Kanda A, Ishida S
Current eye research   42(8) 1149-1154   Aug 2017   [Refereed]
Matsuda T, Noda K, Murata M, Kawasaki A, Kanda A, Mashima Y, Ishida S
Investigative ophthalmology & visual science   58(7) 3254-3261   Jun 2017   [Refereed]
Kanda A, Ishizuka ET, Shibata A, Matsumoto T, Toyofuku H, Noda K, Namba K, Ishida S
Molecular therapy. Nucleic acids   7 116-126   Jun 2017   [Refereed]
Dong Y, Kanda A, Noda K, Saito W, Ishida S
Scientific reports   7 44266   Mar 2017   [Refereed]
Dong Y, Noda K, Murata M, Yoshida S, Saito W, Kanda A, Ishida S
Current eye research   42(1) 111-117   Jan 2017   [Refereed]
Hase K, Kanda A, Hirose I, Noda K, Ishida S
PloS one   12(12) e0189696   2017   [Refereed]
Dong Z, Shinmei Y, Dong Y, Inafuku S, Fukuhara J, Ando R, Kitaichi N, Kanda A, Tanaka K, Noda K, Harada T, Chin S, Ishida S
Heliyon   2(10) e00191   Oct 2016   [Refereed]
Kinoshita S, Noda K, Saito W, Kanda A, Ishida S
Acta ophthalmologica   94(6) e521-3   Sep 2016   [Refereed]
Dong Y, Kase S, Dong Z, Fukuhara J, Tagawa Y, Ishizuka ET, Murata M, Shinmei Y, Ohguchi T, Kanda A, Noda K, Ishida S
International journal of molecular medicine   38(2) 545-550   Aug 2016   [Refereed]
Dong Y, Dong Z, Kase S, Ando R, Fukuhara J, Kinoshita S, Inafuku S, Tagawa Y, Ishizuka ET, Saito W, Murata M, Kanda A, Noda K, Ishida S
International journal of ophthalmology   9(8) 1100-1105   2016   [Refereed]
Kanda A, Noda K, Saito W, Ishida S
Scientific reports   5 17946   Dec 2015   [Refereed]
[Atp6ap2/ (Pro) renin Receptor is Required for Laminar Formation during Retinal Development in Mice].
Kanda A
Nippon Ganka Gakkai zasshi   119(11) 787-798   Nov 2015   [Refereed]
Inafuku S, Noda K, Amano M, Ohashi T, Yoshizawa C, Saito W, Murata M, Kanda A, Nishimura S, Ishida S
Investigative ophthalmology & visual science   56(9) 5316-5322   Aug 2015   [Refereed]
Kanda A, Noda K, Ishida S
The Journal of biological chemistry   290(15) 9690-9700   Apr 2015   [Refereed]
Kitai H, Sakakibara-Konishi J, Oizumi S, Hirohashi Y, Saito W, Kanda A, Sato N, Nishimura M
Lung cancer (Amsterdam, Netherlands)   87(1) 73-76   Jan 2015   [Refereed]
Ishizuka ET, Kanda A, Kase S, Noda K, Ishida S
Investigative ophthalmology & visual science   56(1) 74-80   Dec 2014   [Refereed]
Dong Z, Iwata D, Kitaichi N, Takeuchi M, Sato M, Endo N, Iwabuchi K, Ando R, Fukuhara J, Kinoshita S, Lennikov A, Kitamura M, Mizuuchi K, Kanda A, Noda K, Namba K, Yamagishi S, Ohno S, Ishida S
Journal of leukocyte biology   96(6) 1077-1085   Dec 2014   [Refereed]
[(Pro) renin receptor in the pathogenesis of proliferative diabetic retinopathy].
Kanda A
Nippon Ganka Gakkai zasshi   118(11) 916-926   Nov 2014   [Refereed]
Kinoshita S, Noda K, Tagawa Y, Inafuku S, Dong Y, Fukuhara J, Dong Z, Ando R, Kanda A, Ishida S
The Journal of nutritional biochemistry   25(11) 1177-1182   Nov 2014   [Refereed]
Inafuku S, Noda K, Amano M, Ohashi T, Yoshizawa C, Saito W, Kanda A, Nishimura S, Ishida S
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie   252(8) 1235-1243   Aug 2014   [Refereed]
Ando R, Noda K, Tomaru U, Kamoshita M, Ozawa Y, Notomi S, Hisatomi T, Noda M, Kanda A, Ishibashi T, Kasahara M, Ishida S
Investigative ophthalmology & visual science   55(7) 4682-4690   Jul 2014   [Refereed]
Kinoshita S, Kase S, Ando R, Dong Z, Fukuhara J, Dong Y, Inafuku S, Noda K, Noda M, Kanda A, Ishida S
Investigative ophthalmology & visual science   55(6) 3461-3467   May 2014   [Refereed]
Yaguchi H, Yabe I, Takahashi H, Okumura F, Takeuchi A, Horiuchi K, Kano T, Kanda A, Saito W, Matsumoto M, Nakayama KI, Hatakeyama S, Sasaki H
Journal of neurology   261(1) 224-226   Jan 2014   [Refereed]
Kanda A, Noda K, Yuki K, Ozawa Y, Furukawa T, Ichihara A, Ishida S
The Journal of neuroscience : the official journal of the Society for Neuroscience   33(49) 19341-19351   Dec 2013   [Refereed]
Expression of αB-crystallin and vascular endothelial growth factor in conjunctival squamous cell carcinoma.
Dong Z, Kase S, Ando R, Fukuhara J, Kinoshita S, Dong Y, Takashina S, Kanda A, Noda M, Noda K, Ishida S
Anticancer research   33(9) 3745-3751   Sep 2013   [Refereed]
Ando R, Noda K, Namba S, Saito W, Kanda A, Ishida S
Acta ophthalmologica   92(3) e245-6   Aug 2013   [Refereed]
Kanda A, Noda K, Saito W, Ishida S
The British journal of ophthalmology   97(5) 666-668   May 2013   [Refereed]
Fukuhara J, Kase S, Ohashi T, Ando R, Dong Z, Noda K, Ohguchi T, Kanda A, Ishida S
Histochemistry and cell biology   139(2) 381-389   Feb 2013   [Refereed]
Fukuhara J, Noda K, Murata M, Namba S, Kinoshita S, Dong Z, Ando R, Lennikov A, Kanda A, Ishida S
Investigative ophthalmology & visual science   54(1) 274-279   Jan 2013   [Refereed]
Kase S, Rao NA, Yoshikawa H, Fukuhara J, Noda K, Kanda A, Ishida S
Investigative ophthalmology & visual science   54(1) 57-62   Jan 2013   [Refereed]
Specific inhibition of serine/arginine-rich protein kinase attenuates choroidal neovascularization.
Dong Z, Noda K, Kanda A, Fukuhara J, Ando R, Murata M, Saito W, Hagiwara M, Ishida S
Molecular vision   19 536-543   2013   [Refereed]
Kanda A, Noda K, Saito W, Ishida S
Diabetologia   55(11) 3104-3113   Nov 2012   [Refereed]
Kanda A, Noda K, Oike Y, Ishida S
Laboratory investigation; a journal of technical methods and pathology   92(11) 1553-1563   Nov 2012   [Refereed]
Receptor-associated prorenin system in the pathogenesis of retinal diseases.
Satofuka S, Kanda A, Ishida S
Frontiers in bioscience (Scholar edition)   4 1449-1460   Jun 2012   [Refereed]
Murata M, Noda K, Fukuhara J, Kanda A, Kase S, Saito W, Ozawa Y, Mochizuki S, Kimura S, Mashima Y, Okada Y, Ishida S
Investigative ophthalmology & visual science   53(7) 4055-4062   Jun 2012   [Refereed]
Dong Z, Kase S, Ando R, Fukuhara J, Saito W, Kanda A, Murata M, Noda K, Ishida S
Retina (Philadelphia, Pa.)   32(6) 1190-1196   Jun 2012   [Refereed]
Horie Y, Meguro A, Kitaichi N, Lee EB, Kanda A, Noda K, Song YW, Park KS, Namba K, Ota M, Inoko H, Mizuki N, Ishida S, Ohno S
Rheumatology (Oxford, England)   51(6) 983-986   Jun 2012   [Refereed]
Fukuhara J, Kase S, Noda K, Murata M, Noda M, Ando R, Dong Z, Kanda A, Ishida S
Ophthalmic research   48(1) 33-37   2012   [Refereed]
McKay GJ, Patterson CC, Chakravarthy U, Dasari S, Klaver CC, Vingerling JR, Ho L, de Jong PT, Fletcher AE, Young IS, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Hingorani AD, Sofat R, Dean M, Sawitzke J, Seddon JM, Peter I, Webster AR, Moore AT, Yates JR, Cipriani V, Fritsche LG, Weber BH, Keilhauer CN, Lotery AJ, Ennis S, Klein ML, Francis PJ, Stambolian D, Orlin A, Gorin MB, Weeks DE, Kuo CL, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Wright AF, Hayward C, Baird PN, Guymer RH, Attia J, Thakkinstian A, Silvestri G
Human mutation   32(12) 1407-1416   Dec 2011   [Refereed]
Stanton CM, Yates JR, den Hollander AI, Seddon JM, Swaroop A, Stambolian D, Fauser S, Hoyng C, Yu Y, Atsuhiro K, Branham K, Othman M, Chen W, Kortvely E, Chalmers K, Hayward C, Moore AT, Dhillon B, Ueffing M, Wright AF
Investigative ophthalmology & visual science   52(12) 8828-8834   Nov 2011   [Refereed]
McKay GJ, Silvestri G, Chakravarthy U, Dasari S, Fritsche LG, Weber BH, Keilhauer CN, Klein ML, Francis PJ, Klaver CC, Vingerling JR, Ho L, De Jong PT, Dean M, Sawitzke J, Baird PN, Guymer RH, Stambolian D, Orlin A, Seddon JM, Peter I, Wright AF, Hayward C, Lotery AJ, Ennis S, Gorin MB, Weeks DE, Kuo CL, Hingorani AD, Sofat R, Cipriani V, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Yates JR, Webster AR, Moore AT, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Young IS, Fletcher AE, Patterson CC
American journal of epidemiology   173(12) 1357-1364   Jun 2011   [Refereed]
Tissue factor expression in human pterygium.
Ando R, Kase S, Ohashi T, Dong Z, Fukuhara J, Kanda A, Murata M, Noda K, Kitaichi N, Ishida S
Molecular vision   17 63-69   Jan 2011   [Refereed]
Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina.
Kanda A, Stambolian D, Chen W, Curcio CA, Abecasis GR, Swaroop A
Molecular vision   16 1317-1323   Jul 2010   [Refereed]
Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL, Complications of Age-Related Macular Degeneration Prevention Trial Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A
Proceedings of the National Academy of Sciences of the United States of America   107(16) 7401-7406   Apr 2010   [Refereed]
A comprehensive analysis of sequence variants and putative disease-causing mutations in photoreceptor-specific nuclear receptor NR2E3.
Kanda A, Swaroop A
Molecular vision   15 2174-2184   Oct 2009   [Refereed]
Kanda A, Abecasis G, Swaroop A
The British journal of ophthalmology   92(4) 448-450   Apr 2008   [Refereed]
Kanda A, Chen W, Othman M, Branham KE, Brooks M, Khanna R, He S, Lyons R, Abecasis GR, Swaroop A
Proceedings of the National Academy of Sciences of the United States of America   104(41) 16227-16232   Oct 2007   [Refereed]
Kanda A, Friedman JS, Nishiguchi KM, Swaroop A
Human mutation   28(6) 589-598   Jun 2007   [Refereed]
Kanda A, Takuwa-Kuroda K, Aoyama M, Satake H
The FEBS journal   274(9) 2229-2239   May 2007   [Refereed]
Kanda A, Minakata H
Peptides   27(7) 1755-1761   Jul 2006   [Refereed]
Kanda A, Takahashi T, Satake H, Minakata H
The Biochemical journal   395(1) 125-135   Apr 2006   [Refereed]
Kanda A, Satake H, Kawada T, Minakata H
The Biochemical journal   387(1) 85-91   Apr 2005   [Refereed]
Iwakoshi-Ukena E, Ukena K, Takuwa-Kuroda K, Kanda A, Tsutsui K, Minakata H
The Journal of comparative neurology   477 310-323   Sep 2004   [Refereed]
Kawada T, Kanda A, Minakata H, Matsushima O, Satake H
The Biochemical journal   382(1) 231-237   Aug 2004   [Refereed]
Nozawa Y, Nishihara K, Akizawa Y, Orimoto N, Nakano M, Uji T, Ajioka H, Kanda A, Matsuura N, Kiniwa M
Journal of gastroenterology and hepatology   19(5) 506-511   May 2004   [Refereed]
Kanda A, Takuwa-Kuroda K, Iwakoshi-Ukena E, Furukawa Y, Matsushima O, Minakata H
The Journal of endocrinology   179 281-291   Nov 2003   [Refereed]
Kanda A, Takuwa-Kuroda K, Iwakoshi-Ukena E, Minakata H
Biochemical and biophysical research communications   309(4) 743-748   Oct 2003   [Refereed]
Takuwa-Kuroda K, Iwakoshi-Ukena E, Kanda A, Minakata H
Regulatory peptides   115 139-149   Sep 2003   [Refereed]

Misc

 
なぜ糖尿病で失明するのか〜内科の意見、眼科の意見 糖尿病における眼内炎症性メデイエーター 受容体結合プロレニン系
神田 敦宏
日本抗加齢医学会総会プログラム・抄録集   18回 161-161   May 2018
眼科のトランスレーショナルリサーチ 多機能蛋白質に着目した糖尿病網膜症に対する創薬研究
野田 航介, 村田 美幸, 稲福 沙織, 松田 剛, 吉田 志帆, 董 陽子, 木下 哲志, 安藤 亮, 藤谷 顕雄, 齋藤 理幸, 董 震宇, 森 祥平, 加瀬 諭, 吉澤 史子, 齋藤 航, 神田 敦宏, 石田 晋, 眞島 行彦, 笹瀬 智彦, 天野 麻穂, 大橋 哲, 西村 伸一郎, 今川 貴仁, 白仁田 明生
日本眼科学会雑誌   122(3) 223-248   Mar 2018
近年の基礎研究は、血管内皮増殖因子(vascular endothelial growth factor:VEGF)が糖尿病網膜症の病態形成に主要な役割を演じることを明らかとした。そして、同分子群に対する阻害薬の臨床応用は糖尿病網膜症の治療予後を劇的に改善し、現在我々はanti-VEGF eraと呼ばれるこの時代において同疾患の治療体系が刻々と変貌するのを目の当たりにしている。かつては光凝固と硝子体手術のみが進行した糖尿病網膜症に対する治療手段であったことを考えると隔世の感がある。しかしな...
増殖糖尿病網膜症患者における血漿ガレクチン-1と炎症関連分子との相関解析
長谷 敬太郎, 神田 敦宏, 野田 航介, 石田 晋
日本眼科学会雑誌   122(臨増) 237-237   Mar 2018
糖尿病網膜症における新規血管新生因子ガレクチン-1の発現調節メカニズム
神田 敦宏, 野田 航介, 齋藤 航, 石田 晋
日本眼科学会雑誌   122(2) 132-133   Feb 2018
糖尿病網膜症における新規血管新生因子ガレクチン-1の発現調節メカニズム
神田 敦宏, 野田 航介, 齋藤 航, 石田 晋
生命科学系学会合同年次大会   2017年度 [1P-0023]   Dec 2017

Books etc

 
Novel Tachykinins isolated from the Posterior Salivary Gland of the Cephalopod Octopus vulgaris: Expression and Localization of the Precursor Gene.
Peptide Science 2002. Japan. Protein Research Foundation.   2003   

Conference Activities & Talks

 
Galectin-1, an angiogenic factor associated with diabetic retinopathy, is regulated by advanced glycation end products triggering inflammatory cues
KANDA Atsuhiro
14th Congress of the International Ocular Inflammation Society (IOIS)   Oct 2017   
Advanced glycation end products link inflammatory response to upregulation of galectin-1 in diabetic retinopathy
KANDA Atsuhiro
Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting   May 2017   
Aflibercept traps galectin-1, an angiogenic factor associated with diabetic retinopathy [Invited]
KANDA Atsuhiro
2016 Autumn Meeting of Ophthalmological Society of Taiwan (TOS)   Nov 2016   
Galectin-1 is associated with progression of diabetic retinopathy
KANDA Atsuhiro
XXⅡ Biennial Meeting of the International Society for Eye Research(ISER)   Sep 2016   
Galectin-1 is an angiogenic factor associated with proliferative diabetic retinopathy : Novel target for aflibeccept
KANDA Atsuhiro
ARVO (Association for Research in Vision and Ophthalmology) Annual Meeting   May 2016   

Research Grants & Projects

 
Isolation and cDNA cloning of oxytocin/vasopressin superfamily peptides of Octopus vulgaris