KONNO Hiroyuki

J-GLOBAL         Last updated: Dec 11, 2019 at 13:06
 
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Name
KONNO Hiroyuki
E-mail
konnoyz.yamagata-u.ac.jp

Research Areas

 
 

Academic & Professional Experience

 
1999
 - 
2000
University of Pennsylvania, Postdoctoral fellow
 

Education

 
 
 - 
1999
Pharmaceutical Science, Graduate School, Division of Pharmaceutical Sciences, Tohoku University
 
 
 - 
1994
Biological Science of Agriculturare, Faculty of Agriculture, Tohoku University
 

Published Papers

 
Uenoyama R, Miyazaki M, Miyazaki T, Shigeno Y, Tokairin Y, Konno H, Yamashita T
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   1132 121826   Nov 2019   [Refereed]
Miyakoshi T, Konno H
Organic & biomolecular chemistry   17(11) 2896-2905   Dec 2018   [Refereed]
Han J, Romoff TT, Moriwaki H, Konno H, Soloshonok VA
ACS omega   4(21) 18942-18947   Nov 2019   [Refereed]
Tokairin Y, Soloshonok VA, Moriwaki H, Konno H
Amino acids   51(3) 419-432   Nov 2018   [Refereed]
Kobayashi S, Tokairin Y, Miyakoshi T, Saito T, Nagaoka K, Ikeda Y, Fujii J, Konno H
Analytical biochemistry   578 13-22   Aug 2019   [Refereed]
Hotsumi M, Tajiri M, Nikaido Y, Sato T, Makabe K, Konno H
Bioorganic & medicinal chemistry letters   29(16) 2157-2161   Aug 2019   [Refereed]
Okukawa M, Watanabe T, Miura M, Konno H, Yano S, Nonomura Y
Journal of oleo science   68(8) 759-763   Aug 2019   [Refereed]
Kato S, Sasaki M, Yano S, Konno H
Bioscience, biotechnology, and biochemistry   83(7) 1216-1219   Jul 2019   [Refereed]
Watanabe T, Yamamoto Y, Miura M, Konno H, Yano S, Nonomura Y
Journal of oleo science   68(3) 291-296   Mar 2019   [Refereed]
Nosaka K, Uchiyama R, Tadano K, Endo Y, Hayashi M, Konno H, Mimuro H
Microbiology (Reading, England)   165(2) 224-232   Feb 2019   [Refereed]
Kameda R, Sohma T, Kobayashi K, Uchiyama R, Nosaka K, Konno H, Akaji K, Hattori Y
Chemical & pharmaceutical bulletin   67(3) 253-257   2019   [Refereed]
Sato T, Hotsumi M, Makabe K, Konno H
Bioorganic & medicinal chemistry letters   28(22) 3520-3525   Dec 2018   [Refereed]
Yano S, Suyotha W, Zanma S, Konno H, Cherdvorapong V, Wakayama M
The Journal of general and applied microbiology   64(5) 212-220   Nov 2018   [Refereed]
Investigation for the cyclization of linear tetrapeptides: Synthesis of tentoxin B and dihydrotentoxin.
KONNO Hiroyuki
Tetrahedron   74 6173-6181   Aug 2018   [Refereed]
Kikuchi Mariko, Kurotani Reiko, Konno Hiroyuki
TETRAHEDRON LETTERS   58(43) 4145-4148   Oct 2017   [Refereed]
Murai Y, Mori S, Konno H, Hikichi Y, Kai K
Organic letters   19(16) 4175-4178   Aug 2017   [Refereed]
Konno H, Onuma T, Nitanai I, Wakabayashi M, Yano S, Teruya K, Akaji K
Bioorganic & medicinal chemistry letters   27(12) 2746-2751   Jun 2017   [Refereed]
Yoshino Ryo, Tokairin Yoshinori, Kikuchi Mari, Konno Hiroyuki
TETRAHEDRON LETTERS   58(16) 1600-1603   Apr 2017   [Refereed]
Yoshino Ryo, Tokairin Yoshinori, Konno Hiroyuki
TETRAHEDRON LETTERS   58(16) 1604-1606   Apr 2017   [Refereed]
Tokairin Yoshinori, Konno Hiroyuki
TETRAHEDRON   73(1) 39-45   Jan 2017   [Refereed]
Kikuchi M, Konno H
Bioscience, biotechnology, and biochemistry   80(6) 1066-1069   Jun 2016   [Refereed]
Konno H, Wakabayashi M, Takanuma D, Saito Y, Akaji K
Bioorganic & medicinal chemistry   24(6) 1241-1254   Mar 2016   [Refereed]
Synthesis of β-Hydroxytyrosine, A Component of Burkholdines.
Konno H, Sasaki Y, Sato R, Zhu X, Otsuki Y, Ikoma M
Natural product communications   11(2) 213-218   Feb 2016   [Refereed]
Konno H, Sato T, Saito Y, Sakamoto I, Akaji K
Bioorganic & medicinal chemistry letters   25(22) 5127-5132   Nov 2015   [Refereed]
Konno H, Abumi K, Sasaki Y, Yano S, Nosaka K
Bioorganic & medicinal chemistry letters   25(16) 3199-3202   Aug 2015   [Refereed]
Tokairin Yoshinori, Takeda Sho, Kikuchi Mari, Konno Hiroyuki
TETRAHEDRON LETTERS   56(31) 4642   Jul 2015   [Refereed]
Konno Hiroyuki, Sema Yoshihiro, Tokairin Yoshinori
TETRAHEDRON   71(21) 3433-3438   May 2015   [Refereed]
Tokairin Yoshinori, Takeda Sho, Kikuchi Mari, Konno Hiroyuki
TETRAHEDRON LETTERS   56(21) 2809-2812   May 2015   [Refereed]
Tokairin Yoshinori, Maita Kakeru, Takeda Sho, Konno Hiroyuki
SYNTHESIS-STUTTGART   47(3) 351-358   Feb 2015   [Refereed]
Endo H, Nikaido Y, Nakadate M, Ise S, Konno H
Bioorganic & medicinal chemistry letters   24(24) 5621-5626   Dec 2014   [Refereed]
Kikuchi M, Konno H
Organic letters   16(16) 4324-4327   Aug 2014   [Refereed]
Kikuchi Mari, Konno Hiroyuki
HETEROCYCLES   89(7) 1620-1631   Jul 2014   [Refereed]
Awahara C, Tatsumi T, Furuta S, Shinjoh G, Konno H, Nosaka K, Kobayashi K, Hattori Y, Akaji K
Bioorganic & medicinal chemistry   22(8) 2482-2488   Apr 2014   [Refereed]
Hayashi Maria, Kobayashi Kazuya, Esaki Hiroyoshi, Konno Hiroyuki, Akaji Kenichi, Tazuya Keiko, Yamada Kazuko, Nakabayashi Toshikatsu, Nosaka Kazuto
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS   1844(4) 803-809   Apr 2014   [Refereed]
Konno H, Endo H, Ise S, Miyazaki K, Aoki H, Sanjoh A, Kobayashi K, Hattori Y, Akaji K
Bioorganic & medicinal chemistry letters   24(2) 685-690   Jan 2014   [Refereed]
Kurogome Yuji, Kogiso Masaya, Looi Kok Kong, Hattori Yasunao, Konno Hiroyuki, Hirota Mitsuru, Makabe Hidefumi
TETRAHEDRON   69(39) 8349-8352   Sep 2013   [Refereed]
Konno Hiroyuki, Sema Yoshihiro, Ishii Manabu, Hattori Yasunao, Nosaka Kazuto, Akaji Kenichi
TETRAHEDRON LETTERS   54(36) 4848-4850   Sep 2013   [Refereed]
Kikuchi Mari, Konno Hiroyuki
TETRAHEDRON   69(34) 7098-7101   Aug 2013   [Refereed]
Konno H, Otsuki Y, Matsuzaki K, Nosaka K
Bioorganic & medicinal chemistry letters   23(14) 4244-4247   Jul 2013   [Refereed]
Konno H
Bioscience, biotechnology, and biochemistry   76(7) 1257-1261   Jul 2012   [Refereed]
Nosaka K, Esaki H, Onozuka M, Konno H, Hattori Y, Akaji K
FEMS microbiology letters   330(2) 140-147   May 2012   [Refereed]
Akaji K, Konno H, Mitsui H, Teruya K, Shimamoto Y, Hattori Y, Ozaki T, Kusunoki M, Sanjoh A
Journal of medicinal chemistry   54(23) 7962-7973   Dec 2011   [Refereed]
Konno Hiroyuki, Nosaka Kazuto, Akaji Kenichi
TETRAHEDRON   67(47) 9067-9071   Nov 2011   [Refereed]
Kikuchi M, Watanabe Y, Tanaka M, Akaji K, Konno H
Bioorganic & medicinal chemistry letters   21(16) 4865-4868   Aug 2011   [Refereed]
Kikuchi Mari, Nosaka Kazuto, Akaji Kenichi, Konno Hiroyuki
TETRAHEDRON LETTERS   52(30) 3872-3875   Jul 2011   [Refereed]
Hattori Yasunao, Konno Hiroyuki, Miyoshi Hideto, Makabe Hidefumi
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN   69(2) 159-168   Feb 2011   [Refereed]
Toho Kazuya, Abe Naoki, Yamada Teiko, Ito Yoshifumi, Konno Hiroyuki, Kuwahara Shigefumi, Kiyota Hiromasa
LETTERS IN ORGANIC CHEMISTRY   8(1) 1-4   Jan 2011   [Refereed]
Konno Hiroyuki, Makabe Hidefumi, Hattori Yasunao, Nosaka Kazuto, Akaji Kenichi
TETRAHEDRON   66(40) 7946-7953   Oct 2010   [Refereed]
Tatsumi T, Awahara C, Naka H, Aimoto S, Konno H, Nosaka K, Akaji K
Bioorganic & medicinal chemistry   18(7) 2720-2727   Apr 2010   [Refereed]
Konno Hiroyuki, Takebayashi Yoko, Nosaka Kazuto, Akaji Kenichi
HETEROCYCLES   81(1) 79-89   Jan 2010   [Refereed]
Oasa M, Hattori Y, Konno H, Makabe H
Bioscience, biotechnology, and biochemistry   74(6) 1274-1275   2010   [Refereed]
Makabe Hidefumi, Kuwabara Asuka, Hattori Yasunao, Konno Hiroyuki
HETEROCYCLES   78(9) 2369-2376   Sep 2009   [Refereed]
Konno H, Aimoto S, Smith SO, Nosaka K, Akaji K
Bioorganic & medicinal chemistry   17(16) 5769-5774   Aug 2009   [Refereed]
Tanaka M, Tanaka T, Ohta S, Kawakami T, Konno H, Akaji K, Aimoto S, Saito H
Journal of peptide science : an official publication of the European Peptide Society   15(1) 36-42   Jan 2009   [Refereed]
Nosaka K, Onozuka M, Konno H, Akaji K
FEBS letters   582(29) 3991-3996   Dec 2008   [Refereed]
Akaji K, Konno H, Onozuka M, Makino A, Saito H, Nosaka K
Bioorganic & medicinal chemistry   16(21) 9400-9408   Nov 2008   [Refereed]
Makabe H, Konno H, Miyoshi H
Current drug discovery technologies   5(3) 213-229   Sep 2008   [Refereed]
Hattori Y, Konno H, Abe M, Miyoshi H, Goto T, Makabe H
Bioorganic & medicinal chemistry   15(8) 3026-3031   Apr 2007   [Refereed]
Konno Hiroyuki, Kusumoto Sayako, Kanai Sotaro, Yamahana Yasuyuki, Nosaka Kazuto, Akaji Kenichi
HETEROCYCLES   68(12) 2579-2585   Dec 2006   [Refereed]
Makabe H, Kimura Y, Higuchi M, Konno H, Murai M, Miyoshi H
Bioorganic & medicinal chemistry   14(9) 3119-3130   May 2006   [Refereed]

Misc

 
Mari Onozuka, Hiroyuki Konno, Yuko Kawasaki, Kenichi Akaji, Kazuto Nosaka, Kazuto Nosaka
FEMS Yeast Research   8(2) 266-275   Mar 2008
The physiological significance of thiaminase II, which catalyzes the hydrolysis of thiamin, has remained elusive for several decades. The C-terminal domains of THI20 family proteins (THI20/21/22) and the whole region of PET18 gene product of Sacch...
Hiroyuki Konno, Yasuhiro Okuno, Hidefumi Makabe, Kazuto Nosaka, Akio Onishi, Yoshinari Abe, Atsuya Sugimoto, Kenichi Akaji
Tetrahedron Letters   49(5) 782-785   Jan 2008
Total synthesis of cis-solamin A was accomplished without using protecting groups starting from (-)-muricatacin in 11 steps with an overall yield of 4.5%. The backbone of cis-solamin A was constructed by olefin cross-metathesis between the tetrahy...
Hiroyuki Konno, Sachiyo Aoyama, Kazuto Nosaka, Kenichi Akaji
Synthesis   (23) 3666-3672   Dec 2007
Asymmetric syntheses of all diastereoisomers of β-methoxytyrosine, an unusual amino acid contained in callipeltin A, were accomplished starting from a cinnamyl ester derivative. The stereochemistry of β-methoxytyrosine in callipeltin E was estimat...
Yasunao Hattori, Yasunao Hattori, Yuka Kimura, Aki Moroda, Hiroyuki Konno, Masato Abe, Hideto Miyoshi, Tetsuhisa Goto, Tetsuhisa Goto, Hidefumi Makabe
Chemistry - An Asian Journal   1(6) 894-904   Dec 2006
The asymmetric total synthesis of murisolin, (15R, 16R, 19R, 20S)-murisolin A, and (15R, 16R, 19S, 20S)-16,19-cis-murisolin was performed by using an epoxy alcohol as a versatile chiral building block for synthesizing the stereoisomers of mono-THF...
Hiromi Naka, Kenta Teruya, Jeong Kyu Bang, Saburo Aimoto, Tadashi Tatsumi, Hiroyuki Konno, Kazuto Nosaka, Kenichi Akaji
Bioorganic and Medicinal Chemistry Letters   16(14) 3761-3764   Jul 2006
Core sequences necessary for substrate recognition and its inhibition at the PR/p3 site of HTLV-1 protease were clarified for the first time. From the cleavage rates of peptides containing a part of the PR/p3 site, a heptapeptide was found to be t...

Research Grants & Projects

 
Synthesis and Biological activities of Cysteine Protease Inhibitors
Synthetic Study of Bioactive Peptides with Unusual Amino Acids

Patents

 
Optical active glycol and the synthetic method
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