TAMBE Yukihiro

J-GLOBAL         Last updated: Jun 13, 2019 at 18:55
 
Avatar
Name
TAMBE Yukihiro
URL
http://www.shiga-med.ac.jp/~hqmicro/
Affiliation
Shiga University of Medical Science
Section
Undergraduate School of Medicine, Faculty of Medicine, Shiga University of Medical Science Undergraduate School of Medicine Faculty of Medicine
Job title
Assistant Professor

Research Areas

 
 

Education

 
 
 - 
1996
Graduate School, Division of Pharmaceutical Sciences, Kyoto University
 

Published Papers

 
Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer
Tambe, Y., Terado, T., Kim, C. J., Mukaisho, K., Yoshida, S., Sugihara, H., Tanaka, H., Chida, J., Kido, H., Yamaji, K., Yamamoto, T., Nakano, H., Omura, S. and Inoue, H.
Molecular Carinogenesis   in press    2019   [Refereed]
Anti-oncogenic activities of cyclin D1b siRNA on human bladder cancer cells via induction of apoptosis and suppression of cancer cell stemness and invasiveness.
Kim, C. J., Terado, T., Tambe, Y., Mukaisho, K., Suguhara, H., Kawauchi, A., Inoue, H.
International Journal of Oncology   52(1) 231-240   Jan 2018   [Refereed]
Periostin suppresses in vitro invasiveness via PDK1/Akt/mTOR signaling pathway in a orthotopic model of bladder cancer.
Kim CJ, Tambe Y, Mukaisho K, Sugihara H, Kageyama S, Kawauchi A, Inoue H.
Oncology Letters   13(6) 4276-4284   Jun 2017   [Refereed]
Mol Carcinog   55 52-63   Jan 2016   [Refereed]
Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity
Kim CJ, Tambe Y, Mukaisho K, Sugihara H, Kawauchi A, Inoue H.
Oncology Letters   12 4850-4856   2016   [Refereed]
Role of alternative splicing of periostin in human bladder carcinogenesis.
Int. J. Oncol.   32 161-169   2008
Down-regulation of drs mRNA is associated with the progression of adult T-cell leukemia/lymphoma.
Int. J. Oncol.   30 1343-1348   2007
GADD34 inhibits mammalian target of rapamycin signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress.
Int. J. Mol. Med.   19(3) 475-483   2007

Misc

 
God in a cup
Michaele Weissman, Yukihiro Tambe, Naoko Kubo
   Feb 2018   [Invited]

Conference Activities & Talks

 
Anti tumor activity of a novel PDK4 inhibitor, cryptotanshinone,in pancreatic cancer by suppressing the KRAS expression
Yukihiro Tambe, Tokio Terado, Chul-Jang Kim, Hirofumi Nakano, Ken-ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
28 Sep 2018   
Anti-oncogenic activity of a novel PDK4 inhibitor in bladder cancer by suppressing the H-Ras and cancer stemness
Chul Jang Kim, Tokio Terado, Yukihiro Tambe, Hirofumi Nakano, Akihiro Kawauchi, Hirokazu Inoue
27 Sep 2018   
Effect of PDK4 inhibitor on in vivo tumorigenesis and cancer stemness of human pancreatic cancer cell lines
Yukihiro Tambe, Tokio Terado, Chul-Jang Kim, Hirofumi Nakano,Ken-ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
30 Sep 2017   
Anti-oncogenic activities of cyclin D1b siRNA for human bladder cancer cells via apoptosis and cancer stemness
Chul Jang Kim, Tokio Terado, Yukihiro Tambe, Ken-ichi Mukaisho,Hiroyuki Sugihara, Akihiro Kawauchi, Hirokazu Inoue
28 Sep 2017   
Effect of PDK4 inhibitors on malignant phenotypes of human pancreatic cancer cell lines
Yukihiro Tambe, Chul Jang Kim, Hirofumi Nakano, Hirokazu Inoue
7 Oct 2016   
Anti-oncogenic activity of cyclin D1b siRNA in human bladder cancer cells
Chul Jang Kim, Yukihiro Tambe, Akihiro Kawauchi, Hirokazu Inoue
7 Oct 2016   
Effect of inhibitors for LDH and PDK4 on malignant phenotypes of mouse and human cancer cell lines
Yukihiro Tambe, Chul Jang Kim, Hirokazu Inoue
10 Oct 2015   
Periostin suppresses invasiveness and tumorigenicity via Akt/mTOR pathway in a mouse orthotopic model of bladder cancer
Chul Jang Kim, Yukihiro Tambe, Ken-ichi Mukaisho, Hiroyuki Sugihara, Akihiro Kawauchi, Hirokazu Inoue
9 Oct 2015   
Role of the drs tumor suppressor for regulation of glucose metabolism via LDH-B and malignant transformation
Yukihiro Tambe, Hirokazu Inoue, Chul Jang Kim
26 Sep 2014   
Activation of Akt contributes to the rectal tumorigenesis incyclin D1b transgenic mice
Chul Jang Kim, Yukihiro Tambe, Ken-ichi Mukaisho, Hiroyuki Sugihara, Akihiro Kawauchi, Hirokazu Inoue
26 Sep 2014   
Molecular mechanism of the regulation of Warburg effect by the drs tumor suppressor gene.
Yukihiro Tambe, Hirokazu Inoue.
5 Oct 2013   
Molecular mechanism of female specific rectal carcinogenesis in cyclin D1b transgenic mice
Chul Jang Kim, Yukihiro Tambe, Ken-ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
4 Oct 2013   
In vivo and in vitro oncogenic potential of human cyclin D1b variant
Hirokazu Inoue, Yukihiro Tambe, Ken-ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Gen Kondoh, Chul Jang Kim
21 Sep 2012   
The drs tumor suppressor gene is involved in regulation of Warburg effect
Yukihiro Tambe, Hirokazu Inoue.
20 Sep 2012   
Studies on the oncogenic potential of rectal tumor developed in cyclic D1b transgenic mice
Chul Jang Kim, Yukihiro Tambe, Ken-ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Gen Kondoh, Hirokazu Inoue.
19 Sep 2012   
Role of the drs tumor suppressor in regulation of energy metabolism
Yukihiro Tambe, Hirokazu Inoue.
3 Oct 2011   
Role of cyclin D1b variant in rectal tumorigenesis
TAMBE Yukihiro
3 Oct 2011   
Cell-type dependent regulation of EMT and cell invasiveness of human cancer cells by periostin
Hirokazu Inoue, Kanami Sakamoto, Yukihiro Tambe, Chul Jang Kim
10 Dec 2010   
The drs tumor suppressor is involved in the suppression of viral replication via p38-RSK1-S6 dependent pathway
Yukihiro Tambe, Tokuhiro Chano, Hirokazu Inoue
23 Sep 2010   
Cell-type dependent regulation of EMT and cell invasiveness of cancer cells by periostin
Chul Jang Kim, Yukihiro Tambe, Hirokazu Inoue.
22 Sep 2010   
Functional analysis of variant cyclin D1b on enhances cell invasiveness of human bladder cancer cells
Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Yusaku Okada, Hirokazu Inoue.
3 Oct 2009   
Role of drs tumor suppressor gene in cell survival under energy depletion
Hirokazu Inoue, Tokuhiro Chano, Yukihiro Tambe.
3 Oct 2009   
Suppression of viral replication by the drs tumor suppressor genes
Yukihiro Tambe, Hirokazu Inoue.
1 Oct 2009   
Cyclin D1b variant enhances cell invasiveness of human bladder cancer cells.
Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Yusaku Okada, Hirokazu Inoue.
28 Oct 2008   
Regulation of autophagy maturation by the interaction of Drs tumor suppressor and Rab24.
Yukihiro Tambe, Takahiro Isono, Tokuhiro Chano, Hirokazu Inoue.
28 Oct 2008   
Stress-inducible GADD34 interacts with TSC1/2 to suppress mTOR signaling pathway
Hirokazu Inoue, Kahori Minami, Yukihiro Tambe, Takahiro Isono, Tokuhiro Chano.
5 Oct 2007   
Analysis of oncogenic activities of cyclin D1b variant in human bladder cancer cells.
Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Yusaku Okada, Hirokazu Inoue.
5 Oct 2007   
Roles of stress-inducible GADD34 for cell survival in energy depletion and cellular senescense.
Kahori Minami, Hirokazu Inoue, Yukihiro Tambe, Takahiro Isono, Tokuhiro Chano.
5 Oct 2007   
An apoptosis inducing tumor suppressor, Drs, interacts with Rab24 and regulates the maturation process of autophagy.
Yukihiro Tambe, Takahiro Isono, Tokuhiro Chano, Hirokazu Inoue.
5 Oct 2007   
GADD34 controls cell survival by regulating autophagy
Kahori Minami, Yukihiro Tambe, Hirokazu Inoue, Ryosuke Watanabe, Takahiro Isono, Takahiro Kawakami, Takao Terashita, Tokuhiro Chano
20th IUBMB International Congress, Kyoto   23 Jun 2006   
An apoptosis-inducing tumor suppressor gene, drs, is involved in regulation of autophagy and defence for viral infection.
Yukihiro Tambe, Akitsugu Yamamoto, Takahiro Isono, Tokuhiro Chano, Hirokazu Inoue
20th IUBMB International Congress, Kyoto   23 Jun 2006   
Inhibition of mTOR signaling by GADD34 via TSC1/TSC2 contributes to cell survival against bioenergitic stress
Ryosuke Watanabe, Yukihiro Tambe, Hirokazu Inoue, Kahori Minami, Masataka Haneda, Ken-ichi Isobe, Toshiyuki Kobayashi, Okio Hino, Hidetoshi Okabe, Tokuhiro Chano
20th IUBMB International Congress, Kyoto   21 Jun 2006   
Novel apoptotic pathway induced by the drs gene and tumor suppression
TAMBE Yukihiro
10 Dec 2003   

Research Grants & Projects

 
Study on mechanism of Cyclin D1b
Project Year: 2011   
Study on mechanism of drs