藤村孝志 (TAKASHI FUJIMURA) - マイポータル

基本情報

所属: 広島大学大学院統合生命科学研究科特任助教

研究者番号: 50392098
J-GLOBAL ID: 200901089271363841
researchmap会員ID: 1000357761

研究キーワード

アレルギー、アレルゲン、スギ花粉症、喘息、抗原特異的免疫療法、ワクチン

研究分野

ライフサイエンス / 免疫学 /

論文

Intravenous immunoglobulin (IVIg) acts directly on conventional T cells to suppress T cell receptor signaling.

Ayane Hori, Takashi Fujimura, Mai Murakami, Jungyeon Park, Seiji Kawamoto

Biochemical and biophysical research communications 522(3) 792-798 2020年2月12日
Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3.

Amer Ali Abd El-Hafeez, Hazim O Khalifa, Elham A M Mahdy, Vikas Sharma, Toru Hosoi, Pradipta Ghosh, Koichiro Ozawa, Monica M Montano, Takashi Fujimura, Ahmed R N Ibrahim …

Pharmacological reports : PR 71(2) 289-298 2019年4月
Influences of Maternal Factors Over Offspring Allergies and the Application for Food Allergy.

Takashi Fujimura, Shelly Zing Chin Lum, Yuka Nagata, Seiji Kawamoto, Michiko K Oyoshi

Frontiers in immunology 10 1933-1933 2019年
A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation.

Toshiaki Nakano, Shigeru Goto, Yuki Takaoka, Hui-Peng Tseng, Takashi Fujimura, Seiji Kawamoto, Kazuhisa Ono, Chao-Long Chen

BioFactors (Oxford, England) 44(6) 597-608 2018年11月
A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma.

Amer Ali Abd El-Hafeez, Takashi Fujimura, Rikiya Kamei, Noriko Hirakawa, Kenji Baba, Kazuhisa Ono, Seiji Kawamoto

Cytotechnology 70(3) 899-912 2018年6月
Synergistic tumor suppression by a Perilla frutescens-derived methoxyflavanone and anti-cancer tyrosine kinase inhibitors in A549 human lung adenocarcinoma.

Amer Ali Abd El-Hafeez, Takashi Fujimura, Rikiya Kamei, Noriko Hirakawa, Kenji Baba, Kazuhisa Ono, Seiji Kawamoto

Cytotechnology 70(3) 913-919 2018年6月
Anti-inflammatory intravenous immunoglobulin (IVIg) suppresses homeostatic proliferation of B cells.

Ayane Hori, Takashi Fujimura, Seiji Kawamoto

Cytotechnology 70(3) 921-927 2018年6月
Prominent IgE-binding and cytokine-inducing capacities of a newly cloned N-terminal region of Der f 14, an apolipophorin-like house dust mite allergen.

Kareem Gamal ElRamlawy, Takashi Fujimura, Tsunehiro Aki, Akiyasu Okada, Takayuki Suzuki, Takuya Abe, Takaharu Hayashi, Michael J Epton, Wayne R Thomas, Inas Hussein Rafeet …

Journal of biochemistry 163(1) 51-60 2018年1月1日
Design, Synthesis and Cytotoxicity Evaluation of New 3, 5-Disubstituted-2-Thioxoimidazolidinones.

Khaled R A Abdellatif, Mostafa M Elbadawi, Mohammed T Elsaady, Amer A Abd El-Hafeez, Takashi Fujimura, Seiji Kawamoto, Ahmed I Khodair

Anti-cancer agents in medicinal chemistry 18(4) 573-582 2018年
Intake of a fermented plant product attenuates allergic symptoms without changing systemic immune responses in a mouse model of Japanese cedar pollinosis.

Takashi Fujimura, Ayane Hori, Hideto Torii, Shinsuke Kishida, Yoshinori Matsuura, Seiji Kawamoto

The World Allergy Organization journal 11(1) 31-31 2018年
Der f 35: An MD-2-like house dust mite allergen that cross-reacts with Der f 2 and Pso o 2.

T Fujimura, T Aki, T Isobe, A Matsuoka, T Hayashi, K Ono, S Kawamoto

Allergy 72(11) 1728-1736 2017年11月
A flavanone derivative from the Asian medicinal herb (Perilla frutescens) potently suppresses IgE-mediated immediate hypersensitivity reactions.

Rikiya Kamei, Takashi Fujimura, Miki Matsuda, Kotaro Kakihara, Noriko Hirakawa, Kenji Baba, Kazuhisa Ono, Kenji Arakawa, Seiji Kawamoto

Biochemical and biophysical research communications 483(1) 674-679 2017年1月29日
Plasma Cluster Ions Reduce the IgE-Binding Capacity of House Dust Mite Allergens under a Simulated Indoor Environmental Condition.

Hiroaki Okano, Takashi Fujimura, Norihiko Fukuoka, Takaharu Hayashi, Kazuo Nishikawa, Kazuhisa Ono, Seiji Kawamoto

International archives of allergy and immunology 173(4) 199-203 2017年
Der f 34, a Novel Major House Dust Mite Allergen Belonging to a Highly Conserved Rid/YjgF/YER057c/UK114 Family of Imine Deaminases.

Kareem Gamal ElRamlawy, Takashi Fujimura, Koji Baba, Ji Won Kim, Chika Kawamoto, Toshihide Isobe, Takuya Abe, Kelsey Hodge-Hanson, Diana M Downs, Inas Hussein Refaat …

The Journal of biological chemistry 291(41) 21607-21615 2016年10月7日
Impact of Histone H1 on the Progression of Allergic Rhinitis and Its Suppression by Neutralizing Antibody in Mice.

Toshiaki Nakano, Rikiya Kamei, Takashi Fujimura, Yuki Takaoka, Ayane Hori, Chia-Yun Lai, Kuei-Chen Chiang, Yayoi Shimada, Naoya Ohmori, Takeshi Goto …

PloS one 11(4) e0153630 2016年
Exposure to positively- and negatively-charged plasma cluster ions impairs IgE-binding capacity of indoor cat and fungal allergens.

Kazuo Nishikawa, Takashi Fujimura, Yasuhiro Ota, Takuya Abe, Kareem Gamal ElRamlawy, Miyako Nakano, Tomoaki Takado, Akira Uenishi, Hidechika Kawazoe, Yoshinori Sekoguchi …

The World Allergy Organization journal 9(1) 27-27 2016年
Spectrum of allergens for Japanese cedar pollinosis and impact of component-resolved diagnosis on allergen-specific immunotherapy.

Takashi Fujimura, Seiji Kawamoto

Allergology international : official journal of the Japanese Society of Allergology 64(4) 312-20 2015年10月
Recombinant Fusion Allergens, Cry j 1 and Cry j 2 from Japanese Cedar Pollen, Conjugated with Polyethylene Glycol Potentiate the Attenuation of Cry j 1-Specific IgE Production in Cry j 1-Sensitized Mice and Japanese Cedar Pollen Allergen-Sensitized Monkeys.

Takashi Fujimura, Koji Fujinami, Ryosuke Ishikawa, Minoru Tateno, Yoshio Tahara, Yasushi Okumura, Hisashi Ohta, Hiroyuki Miyazaki, Masaru Taniguchi

International archives of allergy and immunology 168(1) 32-43 2015年
IgE reactivity to a Cry j 3, an allergen of Japanese cedar (Cryptomeria japonica) pollen in dogs with canine atopic dermatitis.

Shota Kubota, Kazuki Miyaji, Yusaku Shimo, Hidekatsu Shimakura, Yukari Takase, Noriaki Okamoto, Akio Kiuchi, Masato Fujimura, Takashi Fujimura, Douglas J DeBoer …

Veterinary immunology and immunopathology 149(1-2) 132-5 2012年9月15日
Immunological parameters associated with the development of allergic rhinitis: A preliminary prospective study

Yasuhiro Uekusa, Ayako Inamine, Syuji Yonekura, Shigetoshi Horiguchi, Takashi Fujimura, Daijyu Sakurai, Heizaburo Yamamoto, Homare Suzuki, Toyoyuki Hanazawa, Yoshitaka Okamoto

AMERICAN JOURNAL OF RHINOLOGY & ALLERGY 26(2) 92-96 2012年3月査読有り

もっとみる

MISC

The challenge towards discrimination of clinical symptoms by component-resolved diagnosis using a repertoire of recombinant house dust mite allergens

K. G. ElRamlawy, T. Fujimura, G. Sumida, R. Murakami, A. Tanaka, T. Hayashi, T. Aki, K. Ono, S. Kawamoto

ALLERGY 71 188-188 2016年8月
A novel methoxyflavanone from a Chinese medicinal herb (Perilla frutescens) induces G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma cells

Amer Ali Abd El Hafeez Mohamed, Takashi Fujimura, Rikiya Kamei, Noriko Hirakawa, Kenji Baba, Miyako Nakano, Kazuhisa Ono, Seiji Kawamoto

CANCER RESEARCH 76 2016年7月

共同研究・競争的資金等の研究課題

IgEを介したアレルギーマーチ発症機序の解明

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2016年4月 - 2019年3月

藤村孝志, 河本正次