YoungSook Yun

Profile Information

Affiliation: School of Life Science, Tokyo University of Pharmacy and Life Sciences

Degree: (BLANK)(Tokyo University of Pharmacy and Life Science)

J-GLOBAL ID: 200901073982165844
researchmap Member ID: 1000360496

Research History

1999 - 2001

国立医薬品食品衛生研究所
1999 - 2001

National Institute of Health Sciences
1997 - 1998

韓国生命工学研究所
1997 - 1998

Korea Research Institute of Bioscience and Biotechnology

Education

Papers

17β-neriifolin from unripe fruits of Cerbera manghas suppressed cell proliferation via the inhibition of HOXA9-dependent transcription and the induction of apoptosis in the human AML cell line THP-1.

Shohei Takase, Young Sook Yun, Fuki Moriya, Saaya Sekine, Satoshi Yotsumoto, Katsunori Miyake, Tadahiro Yahagi, Akihiro Ito, Hideshi Inoue

Journal of natural medicines, 77(1) 180-187, Oct 21, 2022
Retusone A, a Guaiane-Type Sesquiterpene Dimer from Wikstroemia retusa and Its Inhibitory Effects on Histone Acetyltransferase HBO1 Expression.

Young Sook Yun, Tomomi Nakano, Haruhiko Fukaya, Yukio Hitotsuyanagi, Miho Nakamura, Megumi Umetsu, Nobuko Matsushita, Katsunori Miyake, Hiroyuki Fuchino, Nobuo Kawahara …

Molecules (Basel, Switzerland), 27(9), May 3, 2022
HBO1ヒストンアセチルトランスフェラーゼの発現を抑制する天然化合物の探索

中野朋美, 尹永淑, 梅津萌, 松下暢子, 三宅克典, 渕野裕之, 川原信夫, 高橋勇二, 井上英史

日本薬学会年会要旨集, 141年会 29V03-am11S, Mar, 2021
HBO1の発現を抑制する天然化合物の探索

中野朋美, 尹永淑, 梅津萌, 松下暢子, 三宅克典, 渕野裕之, 川原信夫, 柳茂, 高橋勇二, 井上英史

日本薬学会年会要旨集, 140年会 28Q-pm129S, Mar, 2020
A new ent-norabietant diterpenoid from roots of Euphorbia lathyris L.

Young Sook Yun, Yukari Takeda, Haruhiko Fukaya, Hiroyuki Fuchino, Nobuo Kawahara, Shigeru Takahashi, Yuji Takahashi, Hideshi Inoue

TETRAHEDRON LETTERS, 59(29) 2813-2815, Jul, 2018
Piperine-like alkamides from Piper nigrum induce BDNF promoter and promote neurite outgrowth in Neuro-2a cells

Young Sook Yun, Sachie Noda, Shigeru Takahashi, Yuji Takahashi, Hideshi Inoue

Journal of Natural Medicines, 72(1) 238-245, Jan 1, 2018 Peer-reviewed
Two Alkaloids from Bulbs of Lycoris sanguinea M-AXIM. Suppress PEPCK Expression by Inhibiting the Phosphorylation of CREB

Young Sook Yun, Miki Tajima, Shigeru Takahashi, Yuji Takahashi, Mariko Umemura, Haruo Nakano, Hyun Sun Park, Hideshi Inoue

PHYTOTHERAPY RESEARCH, 30(10) 1689-1695, Oct, 2016 Peer-reviewed
A New Bis-seco-abietane Diterpenoid from Hyptis crenata Pohl ex Benth

Young Sook Yun, Haruhiko Fukaya, Takahisa Nakane, Akihito Takano, Shigeru Takahashi, Yuji Takahashi, Hideshi Inoue

ORGANIC LETTERS, 16(23) 6188-6191, Dec, 2014 Peer-reviewed
Phenolic Diterpenes from Rosemary Suppress cAMP Responsiveness of Gluconeogenic Gene Promoters

Young Sook Yun, Sachie Noda, Genta Shigemori, Ryunosuke Kuriyama, Shigeru Takahashi, Mariko Umemura, Yuji Takahashi, Hideshi Inoue

PHYTOTHERAPY RESEARCH, 27(6) 906-910, Jun, 2013 Peer-reviewed
Compounds isolated from Curcuma aromatica Salisb. inhibit human P450 enzymes

Yoshinori Bamba, Young Sook Yun, Akira Kunugi, Hideshi Inoue

JOURNAL OF NATURAL MEDICINES, 65(3-4) 583-587, Jul, 2011 Peer-reviewed
Ovafolinins A-E, Five New Lignans from Lyonia ovalifolia

Kenji Kashima, Kaichi Sano, Young Sook Yun, Hiroji Ina, Akira Kunugi, Hideshi Inoue

CHEMICAL & PHARMACEUTICAL BULLETIN, 58(2) 191-194, Feb, 2010 Peer-reviewed
[Identification methods of terpenoid gum bases using TLC and GC/MS].

Akiyama T, Hayashi A, Yamazaki T, Tada A, Sugimoto N, Yun YS, Kunugi A, Tanamoto K, Kawamura Y

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 51(5) 264-272, 2010 Peer-reviewed
[Examination of original plant of Jamaica quassia extract, a natural bittering agent, based on composition of the constituents].

Tada A, Sugimoto N, Sato K, Akiyama T, Asanoma M, Yun YS, Yamazaki T, Tanamoto K

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 50(1) 16-21, Feb, 2009 Peer-reviewed
Antioxidant phenylpropanoid glycosides from the leaves of Wasabia japonica

Takahiro Hosoya, Young Sook Yun, Akira Kunugi

PHYTOCHEMISTRY, 69(3) 827-832, Feb, 2008 Peer-reviewed
[Survey of synthetic disinfectants in grapefruit seed extract and its compounded products].

Sugimoto N, Tada A, Kuroyanagi M, Yoneda Y, Yun YS, Kunugi A, Sato K, Yamazaki T, Tanamoto K

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 49(1) 56-62, Feb, 2008 Peer-reviewed
Neocrocin A: a novel crocetin glycoside with a unique system for binding sugars isolated from gardenia yellow

Yoshinori Uekusa, Naoki Sugimoto, Kyoko Sato, Young Sook Yun, Akira Kunugi, Takeshi Yamazaki, Ken-ichi Tanamoto

CHEMICAL & PHARMACEUTICAL BULLETIN, 55(11) 1643-1646, Nov, 2007 Peer-reviewed
Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis.

Hiroshi Morita, Michiko Eda, Toru Iizuka, Yusuke Hirasawa, Mitsuhiro Sekiguchi, Young Sook Yun, Hideji Itokawa, Koichi Takeya

Bioorganic & medicinal chemistry letters, 16(17) 4458-61, Sep 1, 2006 Peer-reviewed
Phenylpropanoid derivatives from edible canna, Canna edulis

YS Yun, M Satake, S Katsuki, A Kunugi

PHYTOCHEMISTRY, 65(14) 2167-2171, Jul, 2004 Peer-reviewed
Determination of antioxidant activity of herbs by ESR.

Yun YS, Nakajima Y, Iseda E, Kunugi A

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 44(1) 59-62, Feb, 2003 Peer-reviewed

Misc.

王不留行(Vaccaria segetalis)より単離された新規環状ペプチドsegetalin FおよびJの構造と血管平滑筋弛緩作用

江田理子, 飯塚徹, 平澤祐介, 森田博史, 関口光広, 尹永淑, 糸川秀治, 竹谷孝一

日本生薬学会年会講演要旨集, 53rd, 2006
Flavonoids from Laurus nobilis Leaves

Natural Medicines, 56(3), 120, 2002
Natural medicines(共著) A Cembrane-type Diterpene from Flue-cured Burley Tobacco (Nicotiana TabaccumL)

Natural Medicines, 55(5), 262-264, 2001
Two New Alkaloids from Cigarette Smoke Condensate(共著)

Young Sook YUN, Naoki SUGIMOTO, Setsuko SEKITA, Tamio MAITANI, Takashi YAMADA, Motoyoshi SATAKE

Chem. Pharm. Bull., 48(12) 1990-1991, 2000
An antioxidant Lignan and Other Constituents from the Root Bark of Hibiscus syriacus(共著)

Planta Med., 65(7) 658-660, 1999
Conformational analysis of thiosegetalins by distance geometry calculation

H Morita, YS Yun, K Takeya, H Itokawa

HETEROCYCLES, 47(1) 391-396, Jan, 1998
Triterpenoid Saponin from Vaccaria segetalis(共著)

Phytochemistry, 47(1) 143-144, 1998
Thionation of segetalins A and B, cyclic peptides with estrogen-like activity from seeds of Vaccaria segetalis

H Morita, YS Yun, K Takeya, H Itokawa, O Shirota

BIOORGANIC & MEDICINAL CHEMISTRY, 5(3) 631-636, Mar, 1997
Conformational Perfernece for segetalins G and H, Cyclic peptides with Estrogen-like Activity form Seeds of Vaccaria segetalis(共著)

Biorganic & Medicinal Chemistry, 5(11) 2063-2067, 1997
Cyclic Peptides form Higher Plants. 34. Segetalins G and H, structures and Estrogen-like Activity of Cyclic Pentapeptides form Vaccaria segetalis(共著)

Journal of Natural Products, 60(3) 216-218, 1997
A New Triterpenoid Saponin with Contrctility of Rat uterine from Vaccaria Segetalis(共著)

Biorganic & Medicinal Chemistry Letter, 7(8) 1095-1096, 1997
Conformationa of Cyclic Heptapeptides : Confromational Analysis of Segetalin D and E by Distance Geometry Calculations(共著)

Hiroshi MORITA, Young Sook YUN, Koichi TAKEYA, Hideji ITOKAWA

Chem. Pharm. Bull., 45(5) 883-887, 1997
A Cylic Heptapeptide from Vaccaria Segetalis(共著)

Phytochemistry, 42(2) 439-441, 1996
Estrogen-like Activity of Cyclic Peptides from Vaccaria Segetalis Extracts(共著)

Planta Med., 61(6) 561-562, 1995
Segetalins B, C and D, Three New Cyclic Peptide from Vaccaria Segetalis(共著)

Tetrahedron, 51(21) 6003-6014, 1995
Conformational analysis of a Cyclic hexapeptide, Segetalin A from Vaccaria Segetalis(共著)

Tetrahedron, 51(21) 5987-6002, 1995
A New Cyclic Hexapeptide from Vaccaria Segetalis(共著)

Tetrahedron Letter, 35(51) 9593-9596, 1994
Cytotoxic Coumarins from Roots of Angelica gigas NAKAI(共著)

ITOKAWA HIDEJI, YUN YONGSOOK, MORITA HIROSHI, TAKEYA KOICHI, LEE SANG RAE

Natural Medicines, 48(4) 334-335, 1994

Professional Memberships

THE PHARMACEUTICAL SOCIETY OF JAPAN

Research Projects

A study on bioactivity Compounds from Natural Sources.

Industrial Property Rights

特開2006-069982 抗酸化活性を有する本わさび由来の化合物

奥西勲, 村田充良, 山田一乃, 小林一光, 功刀彰, 細谷孝博, 尹永淑

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