2015年
Identification of antisense RNA stem-loops that inhibit RNA-Protein interactions using a bacterial reporter system
Methods in Molecular Biology
- 巻
- 1240
- 号
- 開始ページ
- 49
- 終了ページ
- 56
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1007/978-1-4939-1896-6_4
- 出版者・発行元
- Humana Press Inc.
RNA-protein interactions play important roles in gene regulation, functional RNA-protein complexes such as the ribosome, and in viral replication. Molecules that regulate specific RNA-protein interactions may be used to dissect biological processes, and to establish the validity of targeting an RNA-protein interaction. There are many examples of biological regulation by antisense RNA stem-loops that form loop-loop and loop-linear RNA-RNA interactions. Here, a bacterial reporter system for the identification of RNA stem-loops that inhibit the formation of RNA-protein complexes through RNA-RNA interactions is described.
- リンク情報
- ID情報
-
- DOI : 10.1007/978-1-4939-1896-6_4
- ISSN : 1064-3745
- PubMed ID : 25352136
- SCOPUS ID : 84919673673