Takikawa Osamu

J-GLOBAL         Last updated: Apr 28, 2015 at 09:58
 
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Name
Takikawa Osamu
Affiliation
National Center for Geriatrics and Gerontrogy
Job title
Associate Professor
Degree
(BLANK)(Kyoto University)

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
       Oversea Researcher
 
1983
 - 
1987
Wakayama Medical College, Research Assistant
 
1987
 - 
1997
Osaka Bioscience Institute, Researcher
 
2001
   
 
- Hokkaido University, Research Assistant
 
1997
 - 
2001
Japan Science and Technology Corporation,
 
2002
   
 
- Hokkaido University, Associate Professor
 

Education

 
 
 - 
1983
Graduate School, Division of Medicine, Kyoto University
 
 
 - 
1977
Faculty of Science, Kanazawa University
 

Published Papers

 
Tanizaki Y, Kobayashi A, Toujima S, Shiro M, Mizoguchi M, Mabuchi Y, Yagi S, Minami S, Takikawa O, Ino K.
Cancer Sci.      May 2014   [Refereed]
Tajima Y, Ishikawa M, Maekawa K, Murayama M, Senoo Y, Nishimaki-Mogami T, Nakanishi H, Ikeda K, Arita M, Taguchi R, Okuno A, Mikawa R, Niida S, Takikawa O, Saito Y.
Lipids Health Dis.   12 68-81   May 2013   [Refereed]
Higashitani K, Kanto T, Kuroda S, Yoshio S, Matsubara T, Kakita N, Oze T, Miyazaki M, Sakakibara M, Hiramatsu N, Mita E, Imai Y, Kasahara A, Okuno A, Takikawa O, Hayashi N, Takehara T.
J Gastroenterol.   48(5) 660-670   May 2013   [Refereed]
NMR-based metabolomics of urine in a mouse model of Alzheimer's disease: identification of oxidative stress biomarkers.
Fukuhara K, Ohno A, Ota Y, Senoo Y, Maekawa K, Okuda H, Kurihara M, Okuno A, Niida S, Saito Y, Takikawa O.
J Clin Biochem Nutr.   52(2) 133-138   Mar 2013   [Refereed]
Tanaka M, Li X, Hikawa H, Suzuki T, Tsutsumi K, Sato M, Takikawa O, Suzuki H, Yokoyama Y.
Bioorg Med Chem.   21(5) 1159-1165   Mar 2013   [Refereed]
Sato N, Saga Y, Mizukami H, Wang D, Takahashi S, Nonaka H, Fujiwara H, Takei Y, Machida S, Takikawa O, Ozawa K, Suzuki M.
Oncol Rep.   28(5) 1574-1578   Nov 2012   [Refereed]
Wang D, Saga Y, Mizukami H, Sato N, Nonaka H, Fujiwara H, Takei Y, Machida S, Takikawa O, Ozawa K, Suzuki M.
Int J Oncol.   40(4) 929-934   Apr 2012   [Refereed]
Nakano S, Takai K, Isaka Y, Takahashi S, Unno Y, Ogo N, Matsuno K, Takikawa O, Asai A.
Biochem Biophys Res Commun.   419(3) 556-561   Mar 2012   [Refereed]
Croitoru-Lamoury J, Lamoury FM, Caristo M, Suzuki K, Walker D, Takikawa O, Taylor R, Brew BJ.
PLoS One.   6(2) e14698   Feb 2011   [Refereed]
Blaschitz A, Gauster M, Fuchs D, Lang I, Maschke P, Ulrich D, Karpf E, Takikawa O, Schimek MG, Dohr G, Sedlmayr P.
PLoS One.   6(7) e21774   2011   [Refereed]
Nonaka H, Saga Y, Fujiwara H, Akimoto H, Yamada A, Kagawa S, Takei Y, Machida S, Takikawa O, Suzuki M.
Int J Oncol.   38(1) 113-120   Sep 2010   [Refereed]
Matsuno K, Takai K, Isaka Y, Unno Y, Sato M, Takikawa O, Asai A.
Bioorg Med Chem Lett.   20(17) 5126-5129   Jul 2010   [Refereed]
Inaba T, Ino K, Kajiyama H, Shibata K, Yamamoto E, Kondo S, Umezu T, Nawa A, Takikawa O, Kikkawa F.
Gynecol Oncol.   117(3) 423-428   Jun 2010   [Refereed]
Onodera T, Jang MH, Guo Z, Yamasaki M, Hirata T, Bai Z, Tsuji NM, Nagakubo D, Yoshie O, Sakaguchi S, Takikawa O, Miyasaka M.
J Immunol.   183(9) 5608-5614   Nov 2009   [Refereed]
Ogasawara N, Oguro T, Sakabe T, Matsushima M, Takikawa O, Isobe K, Nagase F.
J Cell Biochem.   108(3) 716-725   Oct 2009   [Refereed]
Inaba T, Ino K, Kajiyama H, Yamamoto E, Shibata K, Nawa A, Nagasaka T, Akimoto H, Takikawa O, Kikkawa F.
Gynecol Oncol.   115(2) 185-192   Aug 2009   [Refereed]
Brenk M, Scheler M, Koch S, Neumann J, Takikawa O, Häcker G, Bieber T, von Bubnoff D.
J Immunol.   183(1) 145-154   Jul 2009   [Refereed]
Krausse-Opatz B, Wittkop U, Gutzki FM, Schmidt C, Jürgens-Saathoff B, Meier S, Beckmann B, Takikawa O, Morgan MA, Tsikas D, Stichtenoth DO, Wagner AD, Zeidler H, Köhler L.
Microb Pathog.   46(6) 289-297   Jun 2009   [Refereed]
Nisapakultorn K, Makrudthong J, Sa-Ard-Iam N, Rerkyen P, Mahanonda R, Takikawa O.
J Periodontol.   80(1) 114-121   Jan 2009   [Refereed]
Yoshida N, Ino K, Ishida Y, Kajiyama H, Yamamoto E, Shibata K, Terauchi M, Nawa A, Akimoto H, Takikawa O, Isobe K, Kikkawa F.
Clin Cancer Res.   14(22) 7251-7259   Nov 2008   [Refereed]
Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms.
Popov A, Driesen J, Abdullah Z, Wickenhauser C, Beyer M, Debey-Pascher S, Saric T, Kummer S, Takikawa O, Domann E, Chakraborty T, Krönke M, Utermöhlen O, Schultze JL.
J Immunol.   181(7) 4976-4988   Oct 2008   [Refereed]
Ino K, Yamamoto E, Shibata K, Kajiyama H, Yoshida N, Terauchi M, Nawa A, Nagasaka T, Takikawa O, Kikkawa F.
Clin Cancer Res.   14(8) 2310-2317   Apr 2008   [Refereed]
Hara T, Yamakura F, Takikawa O, Hiramatsu R, Kawabe T, Isobe K, Nagase F.
J Immunol Methods.   332(1-2) 162-169   Mar 2008   [Refereed]
Pfaff AW, Mousli M, Sénégas A, Marcellin L, Takikawa O, Klein JP, Candolfi E.
Int J Parasitol.   38(2) 249-258   Feb 2008   [Refereed]
Hara T, Ogasawara N, Akimoto H, Takikawa O, Hiramatsu R, Kawabe T, Isobe K, Nagase F.
Immunol Lett.   116(1) 95-102   Feb 2008   [Refereed]
Hiramatsu R, Hara T, Akimoto H, Takikawa O, Kawabe T, Isobe K, Nagase F.
J Cell Biochem.   103(1) 42-53   Jan 2008   [Refereed]
Scheler M, Wenzel J, Tüting T, Takikawa O, Bieber T, von Bubnoff D.
Am J Pathol.   171(6) 1936-1943   Dec 2007   [Refereed]
Riesenberg R, Weiler C, Spring O, Eder M, Buchner A, Popp T, Castro M, Kammerer R, Takikawa O, Hatz RA, Stief CG, Hofstetter A, Zimmermann W.
Clin Cancer Res.   13(23) 6993-7002   Dec 2007   [Refereed]
Guillemin GJ, Cullen KM, Lim CK, Smythe GA, Garner B, Kapoor V, Takikawa O, Brew BJ.
J Neurosci.   27(47) 12884-12892   Nov 2007   [Refereed]
Suh HS, Zhao ML, Rivieccio M, Choi S, Connolly E, Zhao Y, Takikawa O, Brosnan CF, Lee SC.
J Virol.   81(18) 9838-9850   Sep 2007   [Refereed]
Thomas SR, Terentis AC, Cai H, Takikawa O, Levina A, Lay PA, Freewan M, Stocker R.
J Biol Chem.   282(33) 23778-23787   Aug 2007   [Refereed]
Nakamura T, Shima T, Saeki A, Hidaka T, Nakashima A, Takikawa O, Saito S.
Cancer Sci.   98(6) 874-881   Jun 2007   [Refereed]
Increased synthesis of indoleamine-2,3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer.
Takao M, Okamoto A, Nikaido T, Urashima M, Takakura S, Saito M, Saito M, Okamoto S, Takikawa O, Sasaki H, Yasuda M, Ochiai K, Tanaka T.
Oncol Rep.   17(6) 1333-1339   Jun 2007   [Refereed]
Maekawa S, Mori D, Nishiya T, Takikawa O, Horinouchi T, Nishimoto A, Kajita E, Miwa S.
Biochim Biophys Acta.   1773(6) 1000-1006   Jun 2007   [Refereed]
[Chronic fatigue syndrome and neurotransmitters].
Miwa S, Takikawa O.
Nihon Rinsho.   65(6) 1005-1010   Jun 2007   [Refereed]
Lei ZM, Yang M, Li X, Takikawa O, Rao CV.
Biol Reprod.   76(4) 639-644   Apr 2007   [Refereed]
Ino K, Yoshida N, Kajiyama H, Shibata K, Yamamoto E, Kidokoro K, Takahashi N, Terauchi M, Nawa A, Nomura S, Nagasaka T, Takikawa O, Kikkawa F.
Br J Cancer.   95(11) 1555-1561   Dec 2006   [Refereed]
Nagai K, Takikawa O, Kawakami N, Fukao M, Soma T, Oda A, Nishiya T, Hayashi M, Lu L, Nakano M, Kajita E, Fujita H, Miwa S.
Arch Biochem Biophys.   452(1) 29-37   Aug 2006   [Refereed]
Wingender G, Garbi N, Schumak B, Jüngerkes F, Endl E, von Bubnoff D, Steitz J, Striegler J, Moldenhauer G, Tüting T, Heit A, Huster KM, Takikawa O, Akira S, Busch DH, Wagner H, Hämmerling GJ, Knolle PA, Limmer A.
Eur J Immunol.   36(1) 12-20   Jan 2006   [Refereed]
Nitration and inactivation of IDO by peroxynitrite.
Fujigaki H, Saito K, Lin F, Fujigaki S, Takahashi K, Martin BM, Chen CY, Masuda J, Kowalak J, Takikawa O, Seishima M, Markey SP.
J Immunol.   176(1) 372-379   Jan 2006   [Refereed]
Poljak A, Grant R, Austin CJ, Jamie JF, Willows RD, Takikawa O, Littlejohn TK, Truscott RJ, Walker MJ, Sachdev P, Smythe GA.
Arch Biochem Biophys.   450(1) 9-19   Jan 2006   [Refereed]
Takikawa O.
Biochem Biophys Res Commun.   338(1) 12-19   Dec 2005   [Refereed]
Miwa N, Hayakawa S, Miyazaki S, Myojo S, Sasaki Y, Sakai M, Takikawa O, Saito S.
Mol Hum Reprod.   11(12) 865-870   Dec 2005   [Refereed]
Potula R, Poluektova L, Knipe B, Chrastil J, Heilman D, Dou H, Takikawa O, Munn DH, Gendelman HE, Persidsky Y.
Blood.   106(7) 2382-2390   Oct 2005   [Refereed]
Roy EJ, Takikawa O, Kranz DM, Brown AR, Thomas DL.
Neurosci Lett.   387(2) 95-99   Oct 2005   [Refereed]
Guillemin GJ, Brew BJ, Noonan CE, Takikawa O, Cullen KM.
Neuropathol Appl Neurobiol.   31(4) 395-404   Aug 2005   [Refereed]
Okamoto A, Nikaido T, Ochiai K, Takakura S, Saito M, Aoki Y, Ishii N, Yanaihara N, Yamada K, Takikawa O, Kawaguchi R, Isonishi S, Tanaka T, Urashima M.
Clin Cancer Res.   11(16) 6030-6039   Aug 2005   [Refereed]
Hainz U, Obexer P, Winkler C, Sedlmayr P, Takikawa O, Greinix H, Lawitschka A, Pötschger U, Fuchs D, Ladisch S, Heitger A.
Blood.   105(10) 4127-4134   May 2005   [Refereed]
Nawate S, Fukao M, Sakuma I, Soma T, Nagai K, Takikawa O, Miwa S, Kitabatake A.
Br J Pharmacol.   144(2) 178-189   Jan 2005   [Refereed]
Nakano S, Takai K, Isaka Y, Takahashi S, Unno Y, Ogo N, Matsuno K, Takikawa O, Asai A.
Biochem Biophys Res Commun.   419(3) 556-561   [Refereed]

Misc

 
The Journal of clinical investigation   114: 270-279    2004
Tryptophan pyrrole ring cleavage enzymes in placenta. "jointly worked"
Advances in experimental medicine and biology   527: 425-434    2003

Works

 
Study on Tryptophan Metabolism in Placenta
2001
AIDS Virus Infection and Tryptophan Metabolism
2000
Malaria Infection and Tryptophan Metabolism
2000

Research Grants & Projects

 
Study on Acetyl carnitine transporter
Development of inhibitors for indoleamine 2,3-dioxygenase(tryptophan metabolizing enzyme)
Study on Acetyl Carnitine Transporter in Brain
Study on Tryptophan Metabolism during Malaria Infection
Study on Tryptophan Metabolism in Placenta

Patents

 
特願2013-112444 : 化学・物理現象検出方法及びその装置
滝川修、奥野海良人、吉見立也、澤田和明、奥村弘一
A Surface Antigen Expressed on Activated Macrophages Involved in Cellular Immunity
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