三木隆幸 (Miki Takayuki) - マイポータル - researchmap

基本情報

所属: 札幌医科大学医学部医学科内科学第二講座医学部医学科臨床医学部門講座内科学第二講座助手

学位: 博士（医学）、札幌医科大学

J-GLOBAL ID: 200901035700150395
researchmap会員ID: 1000363277

研究キーワード

1

循環器内科学

受賞

2

2001年

欧州心臓学会Moderated Poster Award
2000年

日本心臓病学会YIA優秀賞

MISC

34

Role of microtubules in ischemic preconditioning against myocardial infarction

Y Nakamura, T Miura, A Nakano, Y Ichikawa, T Yano, H Kobayashi, Y Ikeda, T Miki, K Shimamoto

CARDIOVASCULAR RESEARCH 64(2) 322-330 2004年11月
The role of ADAM protease in the tyrosine kinase-mediated trigger mechanism of ischemic preconditioning

Y Ichikawa, T Miura, A Nakano, T Miki, Y Nakamura, K Tsuchihashi, K Shimamoto

CARDIOVASCULAR RESEARCH 62(1) 167-175 2004年4月
Ischemic preconditioning activates AMPK in a PKC-dependent manner and induces GLUT4 up-regulation in the late phase of cardioprotection

Y Nishino, T Miura, T Miki, J Sakamoto, Y Nakamura, Y Ikeda, H Kobayashi, K Shimamoto

CARDIOVASCULAR RESEARCH 61(3) 610-619 2004年2月
Dietary habits and risk of urothelial cancer death in a large-scale cohort study (JACC Study) in Japan.

Nutr Cancer 50 33-9 2004年
Granulocyte colony stimulating factor/macrophage colony stimulating factor improves postinfarct ventricular function by suppression of border zone remodelling in rats.

Clin Exp Pharmacol Physiol 31 873-82 2004年
Protective role of gap junctions in preconditioning against myocardial infarction.

Am J Physiol Heart Circ Physiol 286 0-21 2004年
ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart.

Curr Vasc Pharmacol 1 251-8 2003年
Does enhanced expression of the Na+-Ca2+ exchanger increase myocardial vulnerability to ischemia/reperfusion injury in rabbit hearts?

Mol Cell Biochem 248(1-2) 141-147 2003年
Interruption of signal transduction between G protein and PKC-epsilon underlies the impaired myocardial response to ischemic preconditioning in postinfarct remodeled hearts.

Mol Cell Biochem 247(1-2) 185-193 2003年
Mitochondrial K-ATP channel-dependent and -independent phases of ischemic preconditioning against myocardial infarction in the rat

Y Nozawa, T Miura, T Miki, Y Ohnuma, T Yano, K Shimamoto

BASIC RESEARCH IN CARDIOLOGY 98(1) 50-58 2003年1月
Effects of neutral endopeptidase 24.11 inhibition on myocardial infarct size and ischemic preconditioning in rabbits

A Nakano, T Miura, T Miki, Y Nozawa, Y Ichikawa, N Ura, K Shimamoto

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 366(4) 335-342 2002年10月
Blockade of the Na+-Ca2+ exchanger is more efficient than blockade of the Na+-H+ exchanger for protection of the myocardium from lethal reperfusion injury

T Matsumoto, T Miura, T Miki, S Genda, K Shimamoto

CARDIOVASCULAR DRUGS AND THERAPY 16(4) 295-301 2002年7月
Blockade of angiotensin II type 1 receptors suppressed free radical production and preserved coronary endothelial function in the rabbit heart after myocardial infarction.

J Cardiovasc Pharmacol 39(1) 49-57 2002年
Opening of mitochondrial K(ATP) channel occurs downstream of PKC-epsilon activation in the mechanism of preconditioning.

Am J Physiol Heart Circ Physiol 283 440-7 2002年
Infarct size limitation by nicorandil: roles of mitochondrial K(ATP) channels, sarcolemmal K(ATP) channels, and protein kinase C.

J Am Coll Cardiol 40 1523-30 2002年
K(ATP) channel opening is an endogenous mechanism of protection against the no-reflow phenomenon but its function is compromised by hypercholesterolemia.

J Am Coll Cardiol 40 1339-46 2002年
Contribution of both the sarcolemmal K-ATP and mitochondrial K-ATP channels to infarct size limitation by K-ATP channel openers: differences from preconditioning in the role of sarcolemmal K-ATP channels

M Tanno, T Miura, A Tsuchida, T Miki, Y Nishino, Y Ohnuma, K Shimamoto

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 364(3) 226-232 2001年9月
Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction.

Basic Res Cardiol 96 446-53 2001年
Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection by Na+-H+ exchange inhibition against ischemia/reperfusion injury.

J Am Coll Cardiol 37 957-63 2001年
Cardioprotective mechanism of ischemic preconditioning is impaired by postinfarct ventricular remodeling through angiotensin II type 1 receptor activation

J Cardiol 37 112-3 2001年

もっとみる

所属学協会

9

共同研究・競争的資金等の研究課題

1

心筋虚血再灌流障害の分子機構と心筋保護、心不全の治療