高畑武功 (Takenori Takahata) - マイポータル

基本情報

所属: 弘前大学大学院医学研究科消化器血液内科学講座准教授

学位: 博士(医学)(弘前大学)

J-GLOBAL ID: 200901060716173373
researchmap会員ID: 1000363651

外部リンク: https://ghi-hirosaki-u.com/

消化器癌、悪性リンパ腫中心に臨床を行っています。

研究キーワード

研究分野

学歴

論文

Influence of Polymorphisms in Pharmacokinetics-Related Genes on the Areas Under the Plasma Concentration-Time Curves of Doxorubicin and Doxorubicinol in Patients with Diffuse Large B-Cell Lymphoma Receiving CHOP Therapy.

Keigo Saito, Takenori Takahata, Junichi Nakagawa, Yu Chen, Kensuke Saito, Kosuke Kamata, Takuto Tachita, Satoru Yamashita, Kayo Ueno, Atsushi Sato …

European journal of drug metabolism and pharmacokinetics 50(3) 219-227 2025年5月
Coexistence of plasmablastic lymphoma and adenocarcinoma in the stomach: a case report and literature review.

Takato Maeda, Takenori Takahata, Shintaro Goto, Takao Oyama, Satoru Nakagawa, Yasuhisa Murai, Ryuma Machida, Nao Ishidoya, Juichi Sakamoto, Hideki Iwamura …

International cancer conference journal 14(2) 155-162 2025年4月
Influence of CYP3A5 and ABCB1 polymorphisms on the pharmacokinetics of vincristine in adult patients receiving CHOP therapy.

Junichi Nakagawa, Takenori Takahata, Yu Chen, Kensuke Saito, Kosuke Kamata, Takuto Tachita, Satoru Yamashita, Keigo Saito, Kayo Ueno, Atsushi Sato …

Cancer chemotherapy and pharmacology 92(5) 391-398 2023年11月
Newly diagnosed extranodal NK/T-cell lymphoma, nasal type, at the injected left arm after BNT162b2 mRNA COVID-19 vaccination.

Takuto Tachita, Takenori Takahata, Satoru Yamashita, Toru Ebina, Kosuke Kamata, Kazufumi Yamagata, Yoshiko Tamai, Hirotake Sakuraba

International journal of hematology 2023年4月24日査読有り
Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole.

Naoya Aiuchi, Junichi Nakagawa, Hirotake Sakuraba, Takenori Takahata, Kosuke Kamata, Norihiro Saito, Kayo Ueno, Masahiro Ishiyama, Kazufumi Yamagata, Hiroyuki Kayaba …

Pharmacology research & perspectives 10(2) e00935 2022年4月
Evaluation for pharmacokinetic exposure of cytotoxic anticancer drugs in elderly patients receiving (R-)CHOP therapy.

Junichi Nakagawa, Takenori Takahata, Rui Hyodo, Yu Chen, Kengo Hasui, Kota Sasaki, Kensuke Saito, Kayo Ueno, Kazuhiro Hosoi, Kazufumi Terui …

Scientific reports 11(1) 785-785 2021年1月12日
大腸癌化学療法の治療選択に有用なバイオマーカー切除不能大腸がんに対するがん薬物療法効果予測バイオマーカーとしてのCMSの意義

大堀久詔, 坂本康寛, 傳田忠道, 高島淳生, 高畑武功, 小松嘉人, 山口達郎, 嶋田顕, 高橋信, 森田智視 …

日本癌治療学会学術集会抄録集 58回 WS7-2 2020年10月
A Case of Non-Resectable Pancreatic Cancer with Multiple Hepatic Metastases Treated with FOLFIRINOX Therapy and Conversion Surgery

Takanobu Akaishi, Keinosuke Ishido, Norihisa Kimura, Hayato Nagase, Tadashi Odagiri, Hiroaki Fujita, Yu Chen, Kensuke Saito, Takenori Takahata, Atsushi Sato …

Gan to kagaku ryoho. Cancer & chemotherapy 46(13) 2551-2553 2019年12月1日
TRICOLORE試験(大腸癌第3相試験:mFOLFOX6/CapeOX+Bev vs S-1/CPT-11+Bev)のQOL解析

佐藤温, 高島淳生, 傳田忠道, 蒲生真紀夫, 高畑武功, 天貝賢二, 倉持英和, 近藤仁, 的場周一郎, 有岡仁 …

日本癌治療学会学術集会抄録集 57回 O38-1 2019年10月
A case of celiac disease with type I enteropathy-associated T-cell lymphoma in a Japanese male patient.

Hiroto Hiraga, Hirotake Sakuraba, Nahoko Tanaka, Rina Watanabe, Yui Akemoto, Shinji Ota, Hidezumi Kikuchi, Manabu Sawaya, Noriko Hiraga, Daisuke Chinda …

Immunological medicine 42(3) 142-147 2019年9月
Intermittent withdrawal of oxaliplatin for alleviating neurotoxicity during oxaliplatin-based chemotherapy for Japanese patients with inoperable or metastatic colorectal cancer: A phase 2 multicenter study

Shunsuke Kato, Hiroo Imai, Makio Gamoh, Takenori Takahata, Hisatsugu Ohori, Katsuhiro Yasuda, Tomohito Niitani, Yasuko Murakawa, Kenji Amagai, Hideki Isobe …

Tohoku Journal of Experimental Medicine 245(1) 21-28 2018年5月1日査読有り
Retrospective analysis of weekly paditaxel chemotherapy for gemcitabine- and S-1-resistant pancreatic cancer

Takenori Takahata, Atsushi Sato, Chen Yu, Kensuke Saito

Japanese Journal of Cancer and Chemotherapy 45(5) 817-821 2018年5月1日
[Microtubule polymerization inhibitors].

Takahata T, Sato A, Saito K, Yamagata K

Nihon rinsho. Japanese journal of clinical medicine 73 Suppl 2 162-166 2015年2月査読有り
[Topoisomerase II inhibitors (anthracyclines)].

Sato A, Takahata T, Saito K

Nihon rinsho. Japanese journal of clinical medicine 73 Suppl 2 178-183 2015年2月査読有り
Use of Granulocyte-Colony Stimulating Factor (G-CSF) in patients with cancer at high risk of febrile neutropenia on the basis of high age and complications, Recommendations for Patients Receiving Radiotherapy, and Adverse Events because of G-CSF

Naoyuki Hanada, Satoshi Tanaka, Takenori Takahata, Atsushi Sato

Japanese Journal of Cancer and Chemotherapy 41(6) 702-706 2014年査読有り
A change in the number of CCSPpos/SPCpos cells in mouse lung during development, growth, and repair

Ruowen Sun, Qiliang Zhou, Xulu Ye, Takenori Takahata, Atsushi Ishiguro, Hiroshi Kijima, Toshihiro Nukiwa, Yasuo Saijo

Respiratory Investigation 51(4) 229-240 2013年12月査読有り
肝転移を伴う切除不能胆管癌に対して化学療法が著効した1例

脇屋太一, 豊木嘉一, 石戸圭之輔, 工藤大輔, 木村憲央, 矢越雄太, 石黒敦, 高畑武功, 佐藤温, 袴田健一

癌と化学療法 40(12) 1753-1755 2013年11月
[A case of unresectable biliary tract cancer with liver metastasis that exhibited an effective response to chemotherapy].

Wakiya T, Toyoki Y, Ishido K, Kudo D, Kimura N, Yakoshi Y, Ishiguro A, Takahata T, Sato A, Hakamada K

Gan to kagaku ryoho. Cancer & chemotherapy 40(12) 1753-1755 2013年11月査読有り
Methylation of the KEAP1 gene promoter region in human colorectal cancer

Naoyuki Hanada, Takenori Takahata, Qiliang Zhou, Xulu Ye, Ruowen Sun, Jugoh Itoh, Atsushi Ishiguro, Hiroshi Kijima, Junsei Mimura, Ken Itoh …

BMC CANCER 12 66 2012年2月査読有り
A case of gastric cancer treated with modified docetaxel, cisplatin and 5-fluorouracil (mDCF) with ingestion inability

Atsushi Ishiguro, Takenori Takahata, Yoshifumi Matsumoto, Satoshi Tanaka, Jugoh Itoh, Hitoshi Kawasaki, Yasuyuki Kudoh, Hiroshi Kijima, Sen Shimaya, Yasuo Saijo

Japanese Journal of Cancer and Chemotherapy 39(3) 465-467 2012年査読有り

もっとみる

MISC

手術により完全切除可能であった後腹膜巨大脂肪肉腫の一例

高畑武功, 舘田哲幸, 工藤沙映, 立田卓登, 鎌田耕輔, 石戸圭之輔, 木村憲央, 脇屋太一, 須藤亜希子, 袴田健一 …

日本癌治療学会学術集会抄録集 60回 P67-5 2022年10月
TRICOLORE 切除不能大腸癌に対するmFOLFOX6/CapeOX+BevとS-1/CPT-11+Bevとの第3相試験

岩永一郎, 岩佐悟, 高畑武功, 天貝賢二, 倉持英和, 辻靖, 的場周一郎, 有岡仁, 江藤和範, 畑中一映 …

日本癌治療学会学術集会抄録集 55回 O30-2 2017年10月
大腸分子標的治療薬ベバシズマブベバシズマブ投与例(一次治療)におけるGlasgow Prognostic Scoreの有用性 HGCSG0802

高畑武功, 結城敏志, 中積宏之, 佐々木尚英, 中村路夫, 岩永一郎, 舘山美樹, 江藤和範, 畑中一映, 工藤峰生 …

日本癌治療学会学術集会抄録集 54回 WS50-5 2016年10月
Observational cohort study of first-line bevacizumab combined with chemotherapy in metastatic colorectal cancer (HGCSG0802): Sub-group analysis by KRAS Exon2 status

Takenori Takahata, Satoshi Yuki, Hiroshi Nakatsumi, Kazuaki Harada, Hiraku Fukushima, Atsushi Sato, Takashi Kato, Takashi Meguro, Michio Nakamura, Nobuyuki Ehira …

JOURNAL OF CLINICAL ONCOLOGY 33(3) 2015年1月
OBSERVATIONAL COHORT STUDY OF 1ST LINE BEVACIZUMAB COMBINED WITH CHEMOTHERAPY IN METASTATIC COLORECTAL CANCER: HGCSG0802

Michio Nakamura, Satoshi Yuki, Kazuaki Harada, Yoshimitsu Kobayashi, Takashi Kato, Minoru Uebayashi, Norikazu Sonoda, Kazunori Eto, Takenori Takahata, Yoshito Komatsu

ANNALS OF ONCOLOGY 25 2014年10月
A CASE OF RELAPSED LYMPHOPLASMACYTIC LYMPHOMA WITH MARKED RESPONSE OF BENDAMUSTINE HYDROCHLORIDE

Takenori Takahata, Satoshi Tanaka, Naoyuki Hanada, Kensuke Saitoh, Hiroto Hiraga, Hirotake Sakuraba, Shinsaku Fukuda, Atsushi Sato

ANNALS OF ONCOLOGY 25 2014年10月
Comparison of cetuximab (Cmab) with panitumumab (Pmab) monotherapy in salvage line against KRAS wild-type patients with metastatic colorectal cancer (mCRC): Analysis of HGCSG0901 and 1002.

Akira Ueda, Satoshi Yuki, Takahide Sasaki, Yoshimitsu Kobayashi, Ayumu Hosokawa, Ayako Doi, Yasushi Tsuji, Hiroyuki Okuda, Takashi Kato, Yutaka Watanabe …

JOURNAL OF CLINICAL ONCOLOGY 32(3) 2014年1月
Phase II trial of S-1 plus split cisplatin (SSP) in patients with advanced gastric cancer (HGCSG0702): Final report.

Satoshi Yuki, Yoshito Komatsu, Hiraku Fukushima, Takahide Sasaki, Yoshimitsu Kobayashi, Kazuaki Harada, Masayoshi Dazai, Susumu Sogabe, Takuto Miyagishima, Atsushi Ishiguro …

JOURNAL OF CLINICAL ONCOLOGY 32(3) 2014年1月
An open, multicenter, phase II clinical trial to evaluate efficacy and safety of S-1 split cisplatin in patients with advanced gastric cancer (AGC): HGCSG0702-Safety analysis

Ichiro Iwanaga, Satoshi Yuki, Hiraku Fukushima, Atsushi Ishiguro, Takenori Takahata, Takuto Miyagishima, Mineo Kudo, Yasuko Uehata, Yuh Sakata, Yoshito Komatsu

JOURNAL OF CLINICAL ONCOLOGY 31(4) 2013年2月
マウスiPS細胞におけるin vitro肺上皮細胞への分化誘導

周啓亮, 叶許緑, 孫若文, 石黒敦, 高畑武功, 西條康夫

日本呼吸器学会誌 1 2012年
Hypermethylation of Keap1 promoter and expression of the downstream genes in human colorectal cancer cell lines

Naoyuki Hanada, Takenori Takahata, Jugoh Itoh, Yasuo Saijo

CANCER RESEARCH 71 2011年4月
3 CASES OF PRIMARY SMALL CELL ESOPHAGEAL CARCINOMA TREATED WITH THERAPY FOR SMALL CELL LUNG CARCINOMA

Atsushi Ishiguro, Takenori Takahata, Jugoh Itoh, Yasuo Saijo

ANNALS OF ONCOLOGY 21 27-27 2010年11月
Trousseau症候群を来した胃癌の1例

川口章吾, 石黒敦, 鈴木一広, 花田直之, 高畑武功, 伊東重豪, 谷口啓, 福田眞作

癌と化学療法 36(2) 317-320 2009年2月
12.縦隔原発と考えられるmalignant fibrous histiocytomaの1例(第47回日本肺癌学会東北支部会,東北支部,支部活動)

広瀬勝己, 花田直之, 高畑武功, 伊東重豪, 西條康夫, 木村大輔, 対馬敬夫, 阿部由直

肺癌 48(6) 794-794 2008年10月20日
間葉系幹細胞は生体の腫瘍増殖を促進させる(Mesenchymal stem cells promote tumor growth in vivo)

鈴木一広, 折口真人, 兼平雅彦, 孫若文, 花田直之, 高畑武功, 伊東重豪, 西條康夫

日本癌学会総会記事 67回 452-452 2008年9月
Chemosensitivity determinants of irinotecan hydrochloride in hepatocellular carcinoma cell lines

Takenori Takahata, Keizou Ookawa, Koji Suto, Masanori Tanaka, Hirohisa Yano, Osamu Nakashima, Masamichi Kojiro, Yoshihiro Tamura, Tomonori Tateishi, Yuh Sakata …

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 102(4) 399-407 2008年4月
早期胃癌を合併したマントル細胞リンパ腫の1例

花畑憲洋, 三上達也, 福田真作, 西谷大輔, 佐々木聡, 高畑武功, 伊東重豪, 佐々木賀広, 鬼島宏, 棟方昭博

日本消化器内視鏡学会雑誌 = Gastroenterological endoscopy 49(7) 1674-1680 2007年7月20日
Sensitive determination of omeprazole and its two main metabolites in human plasma by column-switching high-performance liquid chromatography : Application to pharmacokinetic study in relation to CYP2C19 genotypes

SHIMIZU Mikiko, UNO Tsukasa, NIIOKA Takenori, YAUI FURUKORI Norio, TAKAHATA Takenori, SUGAWARA Kazunobu, TATEISHI Tomonori

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 832(2) 241-248 2006年3月7日
The effect of aging on the relationship between the cytochrome P4502C19 genotype and omeprazole pharmacokinetics

Y Ishizawa, N Yasui-Furukori, T Takahata, M Sasaki, T Tateishi

CLINICAL PHARMACOKINETICS 44(11) 1179-1189 2005年
Influence of hepatic impairment on the pharmacokinetics and pharmacodynamics of landiolol hydrochloride, an ultra-short-acting β1-blocker

Takenori Takahata, Norio Yasui-Furukori, Juichi Sakamoto, Koji Suto, Toshiyuki Suto, Tomonori Tateishi, Akihiro Munakata

Drugs in R and D 6(6) 385-394 2005年