ITOH Yoshinori

J-GLOBAL         Last updated: Dec 11, 2019 at 02:48
 
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Name
ITOH Yoshinori
Affiliation
Gifu University
Section
Graduate School of Medicine
Degree
(BLANK)(Kyushu University)

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
Professor,Dean, Gifu University University Hospital, Division of Pharmacy
 

Published Papers

 
Okamoto Ritsuko, Itoh Yoshinori, Murata Yusuke, Kobayashi Daisuke, Hosoi Masako, Mine Kazunori
Pharmacology   91(3-4) 145-152   Jan 2013   [Refereed]
Prolonged use of benzodiazepines often leads to dependence and withdrawal syndrome. However, the cellular mechanisms underlying benzodiazepine dependence have not been fully clarified. Several investigators have shown an involvement of metabotropi...
A randomized controlled non-inferiority study comparing the antiemetic effect between intravenous granisetron and oral azasetron based on estimated 5-HT3 receptor occupancy.
Endo Junki, Iihara Hirotoshi, Yamada Maya, Yanase Koumei, Kamiya Fumihiko, Ito Fumitaka, Funaguchi Norihiko, Ohno Yasushi, Minatoguchi Shinya, Itoh Yoshinori
Anticancer research   32(9) 3939-47   Sep 2012   [Refereed]
The acute antiemetic effect was compared between oral azasetron and intravenous granisetron based on the 5-hydroxytryptamine(3) (5-HT(3)) receptor occupancy theory.
Okayasu Shinji, Kitaichi Kiyoyuki, Hori Akina, Suwa Tetsuya, Horikawa Yukio, Yamamoto Mayumi, Takeda Jun, Itoh Yoshinori
Biological&pharmaceutical bulletin   35(6) 933-7   2012   [Refereed]
Metformin is a drug to improve glycemic control by reducing insulin resistance and is currently considered to be one of the first-choice drugs for type 2 diabetes mellitus (T2DM). However, during metformin use, adverse drug reactions (ADRs) includ...
Nishigaki Minako, Kawahara Kana, Nawa Masahito, Futamura Manabu, Nishimura Misao, Matsuura Katsuhiko, Kitaichi Kiyoyuki, Kawaguchi Yoshihiro, Tsukioka Tadao, Yoshida Kazuhiro, Itoh Yoshinori
International journal of pharmaceutics   424(1-2) 12-7   Mar 2012   [Refereed]
We developed a fast dissolving oral film containing 4 mg dexamethasone and examined the clinical effect of the film as the antiemetic by a randomized controlled crossover study in breast cancer patients receiving a combination chemotherapy with an...
Ishihara Masashi, Ikesue Hiroaki, Matsunaga Hisashi, Suemaru Katsuya, Kitaichi Kiyoyuki, Suetsugu Kimitaka, Oishi Ryozo, Sendo Toshiaki, Araki Hiroaki, Itoh Yoshinori,
The Clinical journal of pain   28(5) 373-81   Jun 2012   [Refereed]
The aim of this study was to evaluate the effectiveness of prophylactic treatment with laxatives and antiemetics on the incidence of gastrointestinal adverse reactions such as constipation, nausea and vomiting in cancer patients who received oral ...

Misc

 
Michiko Oka, Yoshinori Itoh, Miyuki Wada, Akira Yamamoto, Takuya Fujita, Takuya Fujita
British Journal of Pharmacology   vol. 139, pp. 435-443 435-443
1. The mode of Ca 2+ channel blocking by gabapentin [1-(aminomethyl)cyclohexane acetic acid] was compared to those of other Ca 2+ channel blockers, and the potential role of Ca 2+ channel antagonists in providing protection against hypoxic injury ...
Tomofumi Ohmori, Mitsuhiro Nakamura, Shin Tada, Tadashi Sugiyama, Yoshinori Itoh, Yasuhiro Udagawa, Kazuyuki Hirano
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences   861(1) 95-100   Jan 2008
We developed a sensitive assay for ritodrine (RTD), a β2-adrenergic agonist, in human serum. This method was based upon the selective and sensitive technique by a tandem mass spectrometry (MS/MS) using a hydrophilic interaction chromatography (HIL...
Masashi Ishihara, Hiroaki Ikesue, Hisashi Matsunaga, Hisashi Matsunaga, Katsuya Suemaru, Kiyoyuki Kitaichi, Kimitaka Suetsugu, Ryozo Oishi, Toshiaki Sendo, Toshiaki Sendo, Hiroaki Araki, Yoshinori Itoh
Clinical Journal of Pain   28 373-381   2013
Objectives: The aim of this study was to evaluate the effectiveness of prophylactic treatment with laxatives and antiemetics on the incidence of gastrointestinal adverse reactions such as constipation, nausea and vomiting in cancer patients who re...
Toshiaki Sendo, Yoshinori Itoh, Takeshi Goromaru, Tomoko Sumimura, Mami Saito, Keisei Aki, Takahisa Yano, Ryozo Oishi
British Journal of Pharmacology   138 959-967
1. Intravenous injection of ioxaglate (4 g iodine kg -1), an iodinated radiographic contrast medium, caused a marked protein extravasation, pulmonary oedema and a decrease in the arterial partial oxygen pressure in rats. 2. All of these reactions ...
Takahisa Yano, Takahisa Yano, Yoshinori Itoh, Toshio Kubota, Toshiaki Sendo, Ryozo Oishi
Kidney International   vol. 65: 1654-1663 1654-1663
Background. We previously reported that the apoptotic injury in a porcine renal tubular cell line LLC-PK1 cells induced by radiographic contrast media is attenuated by dibutyl cyclic adenosine monophosphate (cAMP) in a manner dependent on protein ...

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2010 - 2012    Investigator(s): Yoshinori ITOH
We developed for the first time a fast dissolving oral film containing 4 mg dexamethasone (DEX) in cooperation with Tsukioka Film Co.Ltd. In rats, pharmacokinetic properties of DEX were very similar to those obtained after oral administration of D...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2007 - 2008    Investigator(s): Yoshinori ITOH
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2005 - 2006    Investigator(s): Yoshinori ITOH
The protective roles for cyclic AMP and its analogs were determined in the in vitro as well as in vivo models of, cisplatin-induced nephropathy. The transient exposure of a porcine renal tubular cell line LLC-PK_1, cells to a high concentration of...
Adverse reactions of contrast media
The Other Research Programs
Modulation of peripheral histamine release
The Other Research Programs

Patents

 
Tryptase inhibitors
2002-46613
Drugs for prevention or cure of drug-induced acute renal failure
2002-26586
Drugs for prevention of hypersensitivity reactions associated with anticancer agents
2002-26586