YOSHIOKA Yasuo

J-GLOBAL         Last updated: Nov 21, 2019 at 04:24
 
Avatar
Name
YOSHIOKA Yasuo
Affiliation
Osaka University
Section
Research Institute for Microbial Diseases
Job title
Associate Professor
Degree
(BLANK)(Osaka University)

Research Areas

 
 

Education

 
 
 - 
2000
Graduate School, Division of Food and Medical Sciences, Osaka University
 

Published Papers

 
Peptides with the multibasic cleavage site of the hemagglutinin from highly pathogenic influenza viruses act as cell-penetrating via binding to heparan sulfate and neuropilins.
Yamamoto Y, Tamiya S, Shibuya M, Nakase I, Yoshioka Y.
Biochem Biophys Res Commun   512(3) 453-459   May 2019   [Refereed]
Autophagy is a new protective mechanism against the cytotoxicity of platinum nanoparticles in human trophoblasts.
Nakashima A, Higashisaka K, Kusabiraki T, Aoki A, Ushijima A, Ono Y, Tsuda S, Shima T, Yoshino O, Nagano K, Yoshioka Y, Tsutsumi Y, Saito S.
Sci Rep   9(1)    Apr 2019   [Refereed]
Aoyama M, Yoshioka Y, Arai Y, Hirai H, Ishimoto R, Nagano K, Higashisaka K, Nagai T, Tsutsumi Y
Journal of controlled release : official journal of the Controlled Release Society   260 183-193   Aug 2017   [Refereed]
Nagano T, Nagano K, Nabeshi H, Yoshida T, Kamada H, Tsunoda SI, Gao JQ, Higashisaka K, Yoshioka Y, Tsutsumi Y
Biological & pharmaceutical bulletin   40(5) 726-728   May 2017   [Refereed]
Nishijima N, Hirai T, Misato K, Aoyama M, Kuroda E, Ishii KJ, Higashisaka K, Yoshioka Y, Tsutsumi Y
Frontiers in immunology   8(379) 379   Apr 2017   [Refereed]
Handa T, Hirai T, Izumi N, Eto SI, Tsunoda SI, Nagano K, Higashisaka K, Yoshioka Y, Tsutsumi Y
Nanotechnology   28(13) 135101   Mar 2017   [Refereed]
Imai S, Morishita Y, Hata T, Kondoh M, Yagi K, Gao JQ, Nagano K, Higashisaka K, Yoshioka Y, Tsutsumi Y
Biochemical and biophysical research communications   484(3) 543-549   Mar 2017   [Refereed]
Hirai T, Yoshioka Y, Udaka A, Uemura E, Ohe T, Aoshima H, Gao JQ, Kokubo K, Oshima T, Nagano K, Higashisaka K, Mashino T, Tsutsumi Y
Nanoscale research letters   11(1) 449   Dec 2016   [Refereed]
Aoyama M, Hata K, Higashisaka K, Nagano K, Yoshioka Y, Tsutsumi Y
Biochemical and biophysical research communications   480(4) 690-695   Nov 2016   [Refereed]
Relationship between size and surface modification of silica particles and enhancement and suppression of inflammatory cytokine production by lipopolysaccharide- or peptidoglycan-stimulated RAW264.7 macrophages
Uemura E, Yoshioka Y, Hirai T, Handa T, Nagano K, Higashisaka K, Tsutsumi Y.
Journal of Nanoparticle Research   June 2016, 18:165    2016   [Refereed]
Hirai T, Yoshioka Y, Takahashi H, Ichihashi K, Udaka A, Mori T, Nishijima N, Yoshida T, Nagano K, Kamada H, Tsunoda S, Takagi T, Ishii KJ, Nabeshi H, Yoshikawa T, Higashisaka K, Tsutsumi Y
Particle and fibre toxicology   12(1)    Jun 2015   [Refereed]
Short-term changes in intracellular ROS localisation after the silver nanoparticles exposure depending on particle size.
Onodera A, Nishiumi F, Kakiguchi K, Tanaka A, Tanabe N, Honma A, Yayama K, Yoshioka Y, Nakahira K, Yonemura S, Yanagihara I, Tsutsumi Y, Kawai Y.
Toxicol Rep.   Mar 23;2:574-579.    2015   [Refereed]
Polyethyleneimine-coating enhances adenoviral transduction of mesenchymal stem cells.
Yao X, Zhou N, Wan L, Su X, Sun Z, Mizuguchi H, Yoshioka Y, Nakagawa S, Zhao RC, Gao JQ.
Biochem Biophys Res Commun.   2014 May 9;447(3):383-7.    2014   [Refereed]
Acute and chronic nephrotoxicity of platinum nanoparticles in mice
Yoshiaki Yamagishi, Akihiro Watari, Yuya Hayata, X. Li, Yasuo Yoshioka, Masuo Kondoh, Yasuo Tsutsumi, Kiyohito Yagi, K.
Nanoscale Res. Lett.      Sep 2013   [Refereed]
Corresponding author
Robo4 is an effective tumor endothelial marker for antibody-drug conjugates based on the rapid isolation of the anti-Robo4 cell-internalizing antibody
Yoshikawa M, Mukai Y, Okada Y, Tsumori Y, Tsunoda S, Tsutsumi Y, Aird WC, Yoshioka Y, Okada N, Doi T, Nakagawa S.
Blood      Apr 2013   [Refereed]
Mutants of lymphotoxin-α with augmented cytotoxic activity via TNFR1 for use in cancer therapy.
Morishige T, Yoshioka Y, Narimatsu S, Ikemizu S, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Cytokine.   2013 Feb;61(2):578-84.    2013   [Refereed]
Dermal absorption of amorphous nanosilica particles after topical exposure for three days
Pharmazie      Aug 2012   [Refereed]
Distribution and histological effects of intravenously administered amorphous nanosilica particles in the testes of mice.
Morishita Y, Yoshioka Y, Satoh H, Nojiri N, Nagano K, Abe Y, Kamada H, Tsunoda S, Nabeshi H, Yoshikawa T, Tsutsumi Y.
Biochem. Biophys. Res. Commun.      Apr 2012   [Refereed]
Annexin A4 is a possible biomarker for cisplatin susceptibility of malignant mesothelioma cells.
Yamashita T, Nagano K, Kanasaki S, Maeda Y, Furuya T, Inoue M, Nabeshi H, Yoshikawa T, Yoshioka Y, Itoh N, Abe Y, Kamada H, Tsutsumi Y, Tsunoda S
Biochem. Biophys. Res. Commun.      Apr 2012   [Refereed]
Rho GDP-dissociation inhibitor alpha is associated with cancer metastasis in colon and prostate cancer.
Yamashita T, Okamura T, Nagano K, Imai S, Abe Y, Nabeshi H, Yoshikawa T, Yoshioka Y, Kamada H, Tsutsumi Y, Tsunoda S.
Pharmazie      Mar 2012   [Refereed]
Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection
Hirai T, Yoshikawa T, Nabeshi H, Yoshida T, Tochigi S, Ichihashi K, Uji M, Akase T, Nagano K, Abe Y, Kamada H, Itoh N, Tsunoda S, Yoshioka Y, Tsutsumi Y.
Part. Fibre. Toxicol      Feb 2012   [Refereed]
Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure
Nabeshi H, Yoshikawa T, Matsuyama K, Nakazato Y, Arimori A, Isobe M, Tochigi S, Kondoh S, Hirai T, Akase T, Yamashita T, Yamashita K, Yoshida T, Nagano K, Abe Y, Yoshioka Y, Kamada H, Imazawa T, Kondoh M, Yagi K, Mayumi T, Itoh N, Tsunoda S, Tsutsumi Y.
Nanotechnology      Feb 2012   [Refereed]
Intravenous administration of polyethylene glycol-coated (PEGylated) proteins and PEGylated adenovirus elicits an anti-PEG immunoglobulin M response.
Shimizu T, Ichihara M, Yoshioka Y, Ishida T, Nakagawa S, Kiwada H.
Biol Pharm Bull.   2012;35(8):1336-42.    2012   [Refereed]
Optimization and internalization mechanisms of PEGylated adenovirus vector with targeting peptide for cancer gene therapy.
Yao XL, Yoshioka Y, Ruan GX, Chen YZ, Mizuguchi H, Mukai Y, Okada N, Gao JQ, Nakagawa S.
Biomacromolecules.   2012 Aug 13;13(8):2402-9.    2012   [Refereed]
Lysine-deficient lymphotoxin-alfa mutant for site-specific PEGylation.
Narimatsu S, Yoshioka Y, Watanabe H, Masano T, Morishige T, Yao X, Tanabe A, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Cytokine      Nov 2011   [Refereed]
Structure-activity relationship of T-cell receptors based on alanine scanning.
Narimatsu S, Yoshioka Y, Morishige T, Yao X, Tsunoda S, Tsutsumi Y, Nishimura MI, Mukai Y, Okada N, Nakagawa S.
Biochem. Biophys. Res. Commun      Oct 2011   [Refereed]
Detection of titanium dioxide particles on frozen tissue sections using synchrotron radiation X-ray fluorescence analysis.
Morishita Y, Yamashita K, Yoshikawa T, Terada Y, Nabeshi H, Yoshioka Y, Itoh N, Tsutsumi Y.
Pharmazie      Oct 2011   [Refereed]
Tumor vascular targeted delivery of polymer-conjugated adenovirus vector for cancer gene therapy.
Yao X, Yoshioka Y, Morishige T, Eto Y, Narimatsu S, Kawai Y, Mizuguchi H, Gao JQ, Mukai Y, Okada N, Nakagawa S.
Mol Ther      Sep 2011   [Refereed]
Size-dependent immune-modulating effect of amorphous nanosilica particles.
Hirai T, Yoshikawa T, Nabeshi H, Yoshida T, Tochigi S, Uji M, Ichihashi K, Akase T, Yamashita T, Yamashita K, Nagano K, Abe Y, Kamada H, Tsunoda S, Yoshioka Y, Itoh N, Tsutsumi Y.
Pharmazie      Sep 2011   [Refereed]
Fine tuning of receptor-selectivity for tumor necrosis factor-α using a phage display system with one-step competitive panning.
Abe Y, Yoshikawa T, Inoue M, Nomura T, Furuya T, Yamashita T, Nagano K, Nabeshi H, Yoshioka Y, Mukai Y, Nakagawa S, Kamada H, Tsutsumi Y, Tsunoda S.
Biomaterials      Aug 2011   [Refereed]
Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.
Yamashita K, Yoshioka Y, Higashisaka K, Mimura K, Morishita Y, Nozaki M, Yoshida T, Ogura T, Nabeshi H, Nagano K, Abe Y, Kamada H, Monobe Y, Imazawa T, Aoshima H, Shishido K, Kawai Y, Mayumi T, Tsunoda S, Itoh N, Yoshikawa T, Yanagihara I, Saito S, Tsutsumi Y.
Nature Nanotechnology (Nat. Nanotechnol.)      Mar 2011   [Refereed]
Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice.
Yoshida T, Yoshioka Y, Fujimura M, Yamashita K, Higashisaka K, Morishita Y, Kayamuro H, Nabeshi H, Nagano K, Abe Y, Kamada H, Tsunoda S, Itoh N, Yoshikawa T, Tsutsumi Y.
Nanoscale Res. Lett.      Mar 2011   [Refereed]
Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes.
Nabeshi H, Yoshikawa T, Matsuyama K, Nakazato Y, Tochigi S, Kondoh S, Hirai T, Akase T, Yamashita T, Yamashita K, Yoshida T, Nagano K, Abe Y, Yoshioka Y, Kamada H, Imazawa T, Itoh N, Tsunoda S, Tsutsumi Y.
Part. Fibre. Toxicol.      Mar 2011   [Refereed]
Modifying the antigen-immunization schedule improves the variety of monoclonal antibodies obtained from immune-phage antibody libraries against HIV-1 Nef and Vif.
Yoshikawa M, Mukai Y, Tsunoda S, Tsutsumi Y, Yoshioka Y, Okada N, Nakagawa S.
J. Biosci. Bioeng.      Mar 2011   [Refereed]
Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages.
Nabeshi H., Yoshikawa T., Arimori A., Yoshida T., Tochigi S., Kondoh S., Hirai T., Akase T., Nagano K., Abe Y., Kamada H., Tsunoda S., Itoh N., Yoshioka Y., Tsutsumi Y.
Nanoscale Res. Lett      Mar 2011   [Refereed]
Limited expression of reticulocalbin-1 in lymphatic endothelial cells in lung tumor but not in normal lung.
Yoshida Y, Yamashita T, Nagano K, Imai S, Nabeshi H, Yoshikawa T, Yoshioka Y, Abe Y, Kamada H, Tsutsumi Y, Tsunoda S.
Biochem Biophys Res Commun      Feb 2011   [Refereed]
Development of an antibody proteomics system using a phage antibody library for efficient screening of tumor-related biomarker proteins.
Imai S, Nagano K, Yoshida Y, Okamura T, Yamashita T, Abe Y, Yoshikawa T, Yoshioka Y, Kamada H, Mukai Y, Nakagawa S, Tsutsumi Y, Tsunoda S.
Biomaterials      Jan 2011   [Refereed]
Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application.
Nabeshi H, Yoshikawa T, Matsuyama K, Nakazato Y, Matsuo K, Arimori A, Isobe M, Tochigi S, Kondoh S, Hirai T, Akase T, Yamashita T, Yamashita K, Yoshida T, Nagano K, Abe Y, Yoshioka Y, Kamada H, Imazawa T, Nakagawa S, Mayumi T, Itoh N, Tsunoda S, Tsutsumi Y.
Biomaterials      Jan 2011   [Refereed]
Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials.
Higashisaka K, Yoshioka Y, Yamashita K, Morishita Y, Fujimura M, Nabeshi H, Nagano K, Abe Y, Kamada H, Tsunoda S, Yoshikawa T, Itoh N, Tsutsumi Y.
Biomaterials      Jan 2011   [Refereed]
Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.
Nomura T, Abe Y, Kamada H, Shibata H, Kayamuro H, Inoue M, Kawara T, Arita S, Furuya T, Yamashita T, Nagano K, Yoshikawa T, Yoshioka Y, Mukai Y, Nakagawa S, Taniai M, Ohta T, Serada S, Naka T, Tsunoda SI, Tsutsumi Y.
J Control Release.      Jan 2011   [Refereed]
Induction of endoplasmic reticulum-endosome fusion for antigen cross-presentation induced by poly (γ-glutamic acid) nanoparticles.
Mukai Y, Yoshinaga T, Yoshikawa M, Matsuo K, Yoshikawa T, Matsuo K, Niki K, Yoshioka Y, Okada N, Nakagawa S.
J Immunol.   2011 Dec 15;187(12):6249-55.    2011   [Refereed]
Nabeshi H, Yoshikawa T, Akase T, Yoshida T, Tochigi S, Hirai T, Uji M, Ichihashi K, Yamashita T, Higashisaka K, Morishita Y, Nagano K, Abe Y, Kamada H, Tsunoda S, Itoh N, Yoshioka Y, Tsutsumi Y.
Nanoscale Res. Lett.      2011   [Refereed]
The utility of poly(γ-glutamic acid) nanoparticles as antigen delivery carriers in dendritic cell-based cancer immunotherapy.
Matsuo K, Ishii Y, Matsuo K, Yoshinaga T, Akashi M, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
Biol Pharm Bull.      Dec 2010   [Refereed]
Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.
Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S.
J Virol      Dec 2010   [Refereed]
Potential adjuvant effect of intranasal urban aerosols in mice through induction of dendritic cell maturation.
Yoshida T, Yoshioka Y, Fujimura M, Yamashita K, Higashisaka K, Nakanishi R, Morishita Y, Kayamuro H, Nabeshi H, Nagano K, Abe Y, Kamada H, Tsunoda S, Yoshikawa T, Itoh N, Tsutsumi Y
Toxicol Lett      Dec 2010   [Refereed]
Optimized PEGylated adenovirus vector reduces the anti-vector humoral immune response against adenovirus and induces a therapeutic effect against metastatic lung cancer.
Eto Y, Yoshioka Y, Ishida T, Yao X, Morishige T, Narimatsu S, Mizuguchi H, Mukai Y, Okada N, Kiwada H, Nakagawa S.
Biol Pharm Bull   33(9) 1540-1544   Sep 2010   [Refereed]
Cytotoxicity of amorphous silica particles against macrophage-like THP-1 cells depends on particle-size and surface properties
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Pharmazie      Aug 2010   [Refereed]
Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape.
Yamashita K, Yoshioka Y, Higashisaka K, Morishita Y, Yoshida T, Fujimura M, Kayamuro H, Nabeshi H, Yamashita T, Nagano K, Abe Y, Kamada H, Kawai Y, Mayumi T, Yoshikawa T, Itoh N, Tsunoda S, Tsutsumi Y
Inflammation      Aug 2010   [Refereed]
Urban aerosol induce pro-inflammatory cytokine production in macrophages and cause airway inflammation in vivo
Yoshida T, Yoshioka Y, Fujimura M, Kayamuro H, Yamashita K, Higashisaka K, Nakanishi R, Morishita Y, Nabeshi H, Yamashita T, Muroi M, Tanamoto K, Nagano K, Abe Y, Kamada H, Kawai Y, Mayumi T, Itoh N, Yoshikawa T, Tsunoda S, Tsutsumi Y
Biol Pharm Bull      May 2010   [Refereed]
Mutant TNF-alpha, mTNF, K90R, is a novel mucosal vaccine adjuvant candidate against HIV
Kayamuro H, Abe Y, Yoshioka Y, Katayama K, Yoshida T, Yamashita K, Yoshikawa T, Kawai Y, Mayumi T, Hiroi T, Ito N, Nagano K, Kamada H, Tsunoda S, Tsutsumi Y
Pharmazie      Apr 2010   [Refereed]
Generation of mouse macrophages expressing membrane-bound TNF variants with selectivity for TNFR1- or TNFR2. Cytokine
Shibata H, Abe Y, Yoshioka Y, Nomura T, Sato M, Kayamuro H, Kawara T, Arita S, Furuya T, Nagano K, Yoshikawa T, Kamada H, Tsutsumi Y
Cytokine      Apr 2010   [Refereed]
Size-dependent cytotoxic effects of amorphous silica nanoparticles on Langerhans cells
Nabeshi H, Yoshikawa T, Matsuyama K, Nakazato Y, Arimori A, Isobe M, Tochigi S, Kondoh S, Hirai T, Akase T, Yamashita T, Yamashita K, Yoshida T, Nagano K, Abe Y, Yoshioka Y, Kamada H, Imazawa T, Itoh N, Tsunoda S, Tsutsumi Y
Pharmazie      Mar 2010   [Refereed]
Evaluation of synthetic cell-penetrating peptides, pro-rich peptide and octaargine derivatives, as adenovirus vector carrier
Kida S, Eto Y, Yoshioka Y, Nakagawa S, Kawasaki K, Maeda M
Protein Pept Lett      Feb 2010   [Refereed]
Creation of an improved mutant TNF with TNFR1-selectivity and antagonistic activity by phage display technology.
Nomura T, Abe Y, Kamada H, Inoue M, Kawara T, Arita S, Furuya T, Minowa K, Yoshioka Y, Shibata H, Kayamuro H, Yamashita T, Nagano K, Yoshikawa T, Mukai Y, Nakagawa S, Tsunoda S, Tsutsumi Y.
Pharmazie.      Feb 2010   [Refereed]
Kojima H, Mukai Y, Yoshikawa M, Kamei K, Yoshikawa T, Morita M, Inubushi T, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
Bioconjug Chem      2010   [Refereed]
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Biomaterials.   2010 Apr;31(12):3357-63.    2010   [Refereed]
Yoshioka Y, Watanabe H, Morishige T, Yao X, Ikemizu S, Nagao C, Ahmad S, Mizuguchi K, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S
Biomaterials.   2010 Mar;31(7):1935-43.    2010   [Refereed]
Morishige T, Yoshioka Y, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Biochem Biophys Res Commun.   2010 Feb 5;392(2):160-5.    2010   [Refereed]
Morishige T, Yoshioka Y, Tanabe A, Yao X, Mizuguchi H, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Int Immunopharmacol.   2010 Jan;10(1):26-33.    2010   [Refereed]
Structure of the TNF-TNFR2 complex
Mukai Y, Nakamura T, Yoshikawa M, Yoshioka Y, Tsunoda S, Nakagawa S, Yamagata Y, Tsutsumi Y.
Sci Signal.   2010 Nov 16;3(148)    2010   [Refereed]
Matsuo K, Ishii Y, Quan YS, Kamiyama F, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
J Control Release.   2011 Jan 5;149(1):15-20    2011   [Refereed]
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Narimatsu S, Monobe Y, Imazawa T, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S
Biomaterials   2010 Sep;31(26):6833-42    2010   [Refereed]
Yao X, Yoshioka Y, Morishige T, Eto Y, Narimatsu S, Mizuguchi H, Mukai Y, Okada N, Nakagawa S.
Biol Pharm Bull.   2010;33(6):1073-6.    2010   [Refereed]
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Biochem Biophys Res Commun.   2010 Mar 19;393(4):888-93.    2010   [Refereed]
Kanagawa N, Yanagawa T, Mukai Y, Yoshioka Y, Okada N, Nakagawa S
Biochem Biophys Res Commun.   2010 Mar 26;394(1):54-8.    2010   [Refereed]
The use of a mutant TNFalpha as a vaccine adjuvant for the induction of mucosal immune responses
Kayamuro H, Abe Y, Yoshioka Y, Katayama K, Nomura T, Yoshida T, Yamashita K, Yoshikawa T, Kawai Y, Mayumi T, Hiroi T, Itoh N, Nagano K, Kamada H, Tsunoda S, Tsutsumi Y
Biomaterials      Oct 2009   [Refereed]
Arsenic Trioxide Inhibits Human T Cell-Lymphotropic Virus-1-Induced Syncytiums by Down-Regulating gp46
Nabeshi H, Yoshikawa T, Kamada H, Shibata H, Sugita T, Abe Y, Nagano K, Nomura T, Minowa K, Yamashita T, Itoh N, Yoshioka Y, Tsunoda S, Tsutsumi Y
Biol Pharm Bull   32(7) 1286-1288   Jul 2009   [Refereed]
TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant
Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, Yoshikawa T, Hiroi T, Itoh N, Kawai Y, Kamada H, Tsunoda SI, Tsutsumi Y
Biochem Biophys Res Commun      Jul 2009   [Refereed]
Molecular cloning, expression and characterization of a major 38 kDa cochineal allergen
Ohgiya Y, Arakawa F, Akiyama H, Yoshioka Y, Hayashi H, Sakai S, Ito S, Yamakawa Y, Ohgiya S, Ikezawa Z, Teshima R
Journal of Allergy and Clinical Immunology      May 2009   [Refereed]
Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant
Mukai Y, Shibata H, Nakamura T, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y
J Mol Biol      Jan 2009   [Refereed]
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Watanabe H, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
Immunol Lett.   2009 Dec 2;127(1):33-8.    2009   [Refereed]
Yao X, Yoshioka Y, Morishige T, Eto Y, Watanabe H, Okada Y, Mizuguchi H, Mukai Y, Okada N, Nakagawa S.
Gene Ther.   2009 Dec;16(12):1395-404    2009   [Refereed]
Shibata H, Yoshioka Y, Abe Y, Ohkawa A, Nomura T, Minowa K, Mukai Y, Nakagawa S, Taniai M, Ohta T, Kamada H, Tsunoda S, Tsutsumi Y
Biomaterials.   2009 Dec;30(34):6638-47.    2009   [Refereed]
Nomura T, Abe Y, Kamada H, Inoue M, Kawara T, Arita S, Furuya T, Yoshioka Y, Shibata H, Kayamuro H, Yamashita T, Nagano K, Yoshikawa T, Mukai Y, Nakagawa S, Taniai M, Ohta T, Tsunoda S, Tsutsumi Y.
Biochem Biophys Res Commun.   2009 Oct 30;388(4):667-71.    2009   [Refereed]
Eto Y, Yoshioka Y, Asavatanabodee R, Kida S, Maeda M, Mukai Y, Mizuguchi H, Kawasaki K, Okada N, Nakagawa S.
Peptides.   2009 Aug;30(8):1548-52.    2009   [Refereed]
Mukai Y, Nakamura T, Yoshioka Y, Shibata H, Abe Y, Nomura T, Taniai M, Ohta T, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.
J Biochem   2009 Aug;146(2):167-72.    2009   [Refereed]
Mukai Y, Nakamura T, Yoshioka Y, Tsunoda S, Kamada H, Nakagawa S, Yamagata Y, Tsutsumi Y.
Acta Crystallogr Sect F Struct Biol Cryst Commun   F65(Pt 3):295-8.    2009   [Refereed]
Kamei K, Mukai Y, Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
Biomaterials   30(9):1809-14.    2009   [Refereed]
Orally administered apple procyanidins protect against experimental inflammatory bowel disease in mice
Yoshioka Y, Akiyama H, Nakano M, Shoji T, Kanda T, Ohtake Y, Takita T, Matsuda R, Maitani T
Int Immunopharmacol      Dec 2008   [Refereed]
The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models.
Shibata H, Yoshioka Y, Ohkawa A, Abe Y, Nomura T, Mukai Y, Nakagawa S, Taniai M, Ohta T, Mayumi T, Kamada H, Tsunoda S, Tsutsumi Y.
Cytokine      Nov 2008   [Refereed]
Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker.
Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda SI, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S.
Protein Expr Purif.      Sep 2008   [Refereed]
Antitumor mechanism of intratumoral injection with IL-12-expressing adenoviral vector against IL-12-unresponsive tumor.
Kanagawa N, Gao JQ, Motomura Y, Yanagawa T, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
Biochem Biophys Res Commun.      Aug 2008   [Refereed]
Organelle-Targeted Delivery of Biological Macromolecules Using the Protein Transduction Domain: Potential Applications for Peptide Aptamer Delivery into the Nucleus.
Yoshikawa T, Sugita T, Mukai Y, Yamanada N, Nagano K, Nabeshi H, Yoshioka Y, Nakagawa S, Abe Y, Kamada H, Tsunoda SI, Tsutsumi Y.
J Mol Biol.      Jul 2008   [Refereed]
Simple and highly sensitive assay system for TNFR2-mediated soluble- and transmembrane-TNF activity.
Abe Y, Yoshikawa T, Kamada H, Shibata H, Nomura T, Minowa K, Kayamuro H, Katayama K, Miyoshi H, Mukai Y, Yoshioka Y, Nakagawa S, Tsunoda S, Tsutsumi Y.
J Immunol Methods.      Jun 2008   [Refereed]
Comparative study on transduction and toxicity of protein transduction domains.
Sugita T, Yoshikawa T, Mukai Y, Yamanada N, Imai S, Nagano K, Yoshida Y, Shibata H, Yoshioka Y, Nakagawa S, Kamada H, Tsunoda SI, Tsutsumi Y.
Br J Pharmacol.      Mar 2008   [Refereed]
Preparation of a Tat-related transporter peptide for carrying the adenovirus vector into cells.
Kida S, Eto Y, Maeda M, Yoshioka Y, Nakagawa S, Hojo K, Tsuda Y, Mayumia T, Kawasaki K.
Protein Pept Lett.      Feb 2008   [Refereed]
Development of amphiphilic gamma-PGA-nanoparticle based tumor vaccine: potential of the nanoparticulate cytosolic protein delivery carrier.
Yoshikawa T, Okada N, Oda A, Matsuo K, Matsuo K, Mukai Y, Yoshioka Y, Akagi T, Akashi M, Nakagawa S.
Biochem Biophys Res Commun.      Feb 2008   [Refereed]
Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist.
Shibata H, Yoshioka Y, Ohkawa A, Minowa K, Mukai Y, Abe Y, Taniai M, Nomura T, Kayamuro H, Nabeshi H, Sugita T, Imai S, Nagano K, Yoshikawa T, Fujita T, Nakagawa S, Yamamoto A, Ohta T, Hayakawa T, Mayumi T, Vandenabeele P, Aggarwal BB, Nakamura T, Yamagata Y, Tsunoda S, Kamada H, Tsutsumi Y.
J Biol Chem.      Jan 2008   [Refereed]
Tat conjugation of adenovirus vector broadens tropism and enhances transduction efficiency
Yoshioka Y, Asavatanabodee R, Eto Y, Watanabe H, Morishige T, Yao X, Kida S, Maeda M, Mukai Y, Mizuguchi H, Kawasaki K, Okada N, Nakagawa S
Life Sci   2008 Nov 21;83(21-22):747-55.    2008   [Refereed]
Improved cytosolic translocation and tumor-killing activity of Tat-shepherdin conjugates mediated by co-treatment with Tat-fused endosome-disruptive HA2 peptide.
Sugita T, Yoshikawa T, Mukai Y, Yamanada N, Imai S, Nagano K, Yoshida Y, Shibata H, Yoshioka Y, Nakagawa S, Kamada H, Tsunoda S, Tsutsumi Y.
Biochem Biophys Res Commun.      Nov 2007   [Refereed]
Efficient generation of antigen-specific cellular immunity by vaccination with poly(gamma-glutamic acid) nanoparticles entrapping endoplasmic reticulum-targeted peptides.
Matsuo K, Yoshikawa T, Oda A, Akagi T, Akashi M, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
Biochem Biophys Res Commun.      Nov 2007   [Refereed]
Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration.
Gao JQ, Eto Y, Yoshioka Y, Sekiguchi F, Kurachi S, Morishige T, Yao X, Watanabe H, Asavatanabodee R, Sakurai F, Mizuguchi H, Okada Y, Mukai Y, Tsutsumi Y, Mayumi T, Okada N, Nakagawa S.
J Control Release.      Sep 2007   [Refereed]
Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants.
Shibata H, Kamada H, Kobayashi-Nishibata K, Yoshioka Y, Nishibata T, Abe Y, Nomura T, Nabeshi H, Minowa K, Mukai Y, Nakagawa S, Mayumi T, Tsunoda S, Tsutsumi Y.
Biochim Biophys Acta.      Aug 2007   [Refereed]
A strategy for efficient cross-presentation of CTL-epitope peptides leading to enhanced induction of in vivo tumor immunity.
Hayashi A, Wakita H, Yoshikawa T, Nakanishi T, Tsutsumi Y, Mayumi T, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
J Control Release.      Jan 2007   [Refereed]
Yao X, Yoshioka Y, Eto Y, Morishige T, Okada Y, Mizuguchi H, Mukai Y, Okada N, Nakagawa S.
Biochem Biophys Res Commun.   362(2):419-24.    2007   [Refereed]
Interlaboratory evaluation of two enzyme-linked immunosorbent assay kits for the detection of egg, milk, wheat, buckwheat, and peanut in foods.
Matsuda R, Yoshioka Y, Akiyama H, Aburatani K, Watanabe Y, Matsumoto T, Morishita N, Sato H, Mishima T, Gamo R, Kihira Y, Maitani T.
J AOAC Int.      Nov 2006   [Refereed]
Chondroitin sulfate intake inhibits the IgE-mediated allergic response by down-regulating Th2 responses in mice.
Sakai S, Akiyama H, Sato Y, Yoshioka Y, Linhardt RJ, Goda Y, Maitani T, Toida T.
J Biol Chem      Jul 2006   [Refereed]
Profile analysis and immunoglobulin E reactivity of wheat protein hydrolysates.
Akiyama H, Sato Y, Watanabe T, Nagaoka MH, Yoshioka Y, Shoji T, Kanda T, Yamada K, Totsuka M, Teshima R, Sawada J, Goda Y, Maitani T.
Int Arch Allergy Immunol      Mar 2006   [Refereed]
Dietary unripe apple polyphenol inhibits the development of food allergies in murine models.
Akiyama H, Sato Y, Watanabe T, Nagaoka MH, Yoshioka Y, Shoji T, Kanda T, Yamada K, Totsuka M, Teshima R, Sawada J, Goda Y, Maitani T.
FEBS Lett.      Aug 2005   [Refereed]
Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window.
Shibata H, Yoshioka Y, Ikemizu S, Kobayashi K, Yamamoto Y, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Hayakawa T, Nagata S, Yamagata Y, Mayumi T, Kamada H, Tsutsumi Y.
Clin Cancer Res.      Dec 2004   [Refereed]

Misc

 
Higashisaka K, Nagano K, Yoshioka Y, Tsutsumi Y
Biological & pharmaceutical bulletin   40(3) 243-248   Mar 2017   [Refereed]
Yoshioka Y, Kuroda E, Hirai T, Tsutsumi Y, Ishii KJ
Frontiers in immunology   8 169   Feb 2017   [Refereed]
Resent topics on development of nanomaterials and nano-safety science
Yoshioka Y., Tsutsumi Y.
Yakugaku Zasshi, 133(2):149-50, 2013.      Feb 2013
Recent topics about nano-safety science and its future
Yoshioka Y., Yoshikawa T., Nabeshi H., Tsutsumi Y.
Yakugaku Zasshi      Feb 2013
The safety assessment of nanomaterials for development of nano-cosmetics
Yoshida T., Yoshioka Y., Tsustumi Y.
Yakugaku Zasshi      Nov 2012
The safety assessment of nanomaterials in reproductive developmental field
Yamashita K., Yoshioka Y.
Yakugaku Zasshi      Mar 2012
Carbone nanonmaterials: efficacy and safety for nanomedicine
10. Yamashita T, Yamashita K, Nabeshi H, Yoshikawa T, Yoshioka Y, Tsunoda S, Tsutsumi Y
Materials   5: 350-363    2012   [Refereed]
Development of a novel DDS for site-specific PEGylated proteins
Yoshioka Y., Tsunoda S., Tsutsumi Y.
Chem. Cent. J. (Chemistry Central Journal)      Dec 2011   [Refereed]
Safety evaluation study of nanomaterials aimed at the promotion of the social reception.
Gene. Environ      Mar 2011   [Refereed]
Identification of New Candidates as Mucosal Vaccine Adjuvant in TNF Family Cytokines
6. Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Arita S, Nomura T, Yoshikawa T, Itoh N, Kamada H, Tsunoda S, Tsutsumi Y
Adv Exp Med Biol   691: 299-304    2011   [Refereed]
Anti-inflammatory Effects of a Novel TNFR1-Selective Antagonistic TNF Mutant on Established Murine Collagen-Induced Arthritis
7. Abe Y, Nomura T, Yoshioka Y, Kamada H, Tsunoda S, Tsutsumi Y
Adv Exp Med Biol   691: 493-500    2011   [Refereed]
Development of PEGylated adenovirus vector with targeting ligand.
Eto Y, Yoshioka Y, Mukai Y, Okada N, Nakagawa S.
Int J Pharm.      Aug 2008   [Refereed]
Phage display and PEGylation of therapeutic proteins.
Mukai Y, Yoshioka Y, Tsutsumi Y.
Comb Chem High Throughput Screen.      May 2005
Bioconjugation of proteins with polymeric modifiers for improvement of their therapeutic efficacy.
Mukai Y, Tsutsumi Y Yoshioka Y, Mayumi T
Current Topics in Peptide & Protein Reserch      Aug 2004
Recent progress on tumor missile therapy and tumor vascular targeting therapy as a new approach.
Yoshioka Y, Tsutsumi Y, Nakagawa S, Mayumi T.
Curr Vasc Pharmacol.      Jul 2004   [Refereed]
Construction and evaluation of phage-displayed naive antibody libraries derived from human, mouse and rabbit
29th Annual Meeting of the Controlled Relearse Society      2002
Cytomedical therapy for diabetes mellitus using microencapsulated pancreatic beta cell line with glucose sensor
Millennial world Congress of Pharmaceutical Sciences      2000
Development of the novel cytomedical device that can protect against humoral immunity
Millennial world Congress of Pharmaceutical Sciences   

Books etc

 
Biological Effects of Fibrous and Particulate Substances
Hirai T, Yoshioka Y, Higashisaka K, Tsutsumi Y (Part:Joint Work, Potential hazards of skin exposure to nanoparticles)
Springer   Jan 2016   ISBN:978-4-431-55732-6
Reproductive and developmental effects of nanomaterials
Morishita Y, Yoshioka Y, Higashisaka K, Tsutsumi Y (Part:Joint Work, Reproductive and developmental effects of nanomaterials)
Springer   Jan 2016   ISBN:978-4-431-55731-9
Nanomaterials in Pharmacology
Yoshioka Y, Higashisaka K, Tsutsumi Y (Part:Joint Work, Biocompatibility of nanomaterials)
Springer   2016   
Engineered Cell Manipulation for Biomedical Application
Yoshioka Y, Higashisaka K, Tsunoda S, Tsutsumi Y (Part:Joint Work, The absorption, distribution, metabolism, and excretion profile of nanoparticles)
Springer   2014   
Recent Developments in Gene Therapy
Eto Y, Yoshioka Y, Mukai Y, Okada N, Nakagawa S (Part:Joint Work, Improvement of adenovirus vectors for cancer gene therapy)
Research Sigupost in India   2007   

Research Grants & Projects

 
Development of the device for organ targeting.