宮城琢也 (Takuya Miyagi) - マイポータル

基本情報

所属: 大阪大学消化器内科学助教

学位: 医学博士(大阪大学)

J-GLOBAL ID: 200901022281668384
researchmap会員ID: 1000367285

研究キーワード

研究分野

経歴

2008年 - 2011年

大阪大学大学院消化器内科学特任助教（グローバルCOE）
2011年

- 大阪大学大学院消化器内科学助教
2008年

Assistant Professor, Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine.
2004年 - 2007年

米国ブラウン大学医学部博士研究員
2004年

Post-doctoral Research Associate, Department of Molecular Microbiology and Immunology, Brown University.

学歴

受賞

MISC

Delayed-Onset Caspase-Dependent Massive Hepatocyte Apoptosis upon Fas Activation in Bak/Bax-Deficient Mice

Hayato Hikita, Tetsuo Takehara, Takahiro Kodama, Satoshi Shimizu, Minoru Shigekawa, Atsushi Hosui, Takuya Miyagi, Tomohide Tatsumi, Hisashi Ishida, Wei Li …

HEPATOLOGY 54(1) 240-251 2011年7月
The efficacy of extended treatment with pegylated interferon plus ribavirin in patients with HCV genotype 1 and slow virologic response in Japan

Tsugiko Oze, Naoki Hiramatsu, Takayuki Yakushijin, Kiyoshi Mochizuki, Kazuho Imanaka, Akira Yamada, Masahide Oshita, Akira Kaneko, Hideki Hagiwara, Eiji Mita …

JOURNAL OF GASTROENTEROLOGY 46(7) 944-952 2011年7月
The efficacy of extended treatment with pegylated interferon plus ribavirin in patients with HCV genotype 1 and slow virologic response in Japan

Tsugiko Oze, Naoki Hiramatsu, Takayuki Yakushijin, Kiyoshi Mochizuki, Kazuho Imanaka, Akira Yamada, Masahide Oshita, Akira Kaneko, Hideki Hagiwara, Eiji Mita …

JOURNAL OF GASTROENTEROLOGY 46(7) 944-952 2011年7月
Delayed-Onset Caspase-Dependent Massive Hepatocyte Apoptosis upon Fas Activation in Bak/Bax-Deficient Mice

Hayato Hikita, Tetsuo Takehara, Takahiro Kodama, Satoshi Shimizu, Minoru Shigekawa, Atsushi Hosui, Takuya Miyagi, Tomohide Tatsumi, Hisashi Ishida, Wei Li …

HEPATOLOGY 54(1) 240-251 2011年7月
BH3-only Activator Proteins Bid and Bim Are Dispensable for Bak/Bax-dependent Thrombocyte Apoptosis Induced by Bcl-xL Deficiency MOLECULAR REQUISITES FOR THE MITOCHONDRIAL PATHWAY TO APOPTOSIS IN PLATELETS

Takahiro Kodama, Tetsuo Takehara, Hayato Hikita, Satoshi Shimizu, Minoru Shigekawa, Wei Li, Takuya Miyagi, Atsushi Hosui, Tomohide Tatsumi, Hisashi Ishida …

JOURNAL OF BIOLOGICAL CHEMISTRY 286(16) 13905-13913 2011年4月
BH3-only Activator Proteins Bid and Bim Are Dispensable for Bak/Bax-dependent Thrombocyte Apoptosis Induced by Bcl-xL Deficiency MOLECULAR REQUISITES FOR THE MITOCHONDRIAL PATHWAY TO APOPTOSIS IN PLATELETS

Takahiro Kodama, Tetsuo Takehara, Hayato Hikita, Satoshi Shimizu, Minoru Shigekawa, Wei Li, Takuya Miyagi, Atsushi Hosui, Tomohide Tatsumi, Hisashi Ishida …

JOURNAL OF BIOLOGICAL CHEMISTRY 286(16) 13905-13913 2011年4月
Amino Acid Substitution in the Core Protein has no Impact on Relapse in Hepatitis C Genotype 1 Patients Treated With Peginterferon and Ribavirin

Yuko Inoue, Naoki Hiramatsu, Tsugiko Oze, Takayuki Yakushijin, Kiyoshi Mochizuki, Kazuto Fukuda, Eiji Mita, Yoshimichi Haruna, Atsuo Inoue, Yasuharu Imai …

JOURNAL OF MEDICAL VIROLOGY 83(3) 419-427 2011年3月
Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice

Minoru Shigekawa, Tetsuo Takehara, Takahiro Kodama, Hayato Hikita, Satoshi Shimizu, Wei Li, Takuya Miyagi, Atsushi Hosui, Tomohide Tatsumi, Hisashi Ishida …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 406(4) 614-620 2011年3月
Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice

Minoru Shigekawa, Tetsuo Takehara, Takahiro Kodama, Hayato Hikita, Satoshi Shimizu, Wei Li, Takuya Miyagi, Atsushi Hosui, Tomohide Tatsumi, Hisashi Ishida …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 406(4) 614-620 2011年3月
Amino Acid Substitution in the Core Protein has no Impact on Relapse in Hepatitis C Genotype 1 Patients Treated With Peginterferon and Ribavirin

Yuko Inoue, Naoki Hiramatsu, Tsugiko Oze, Takayuki Yakushijin, Kiyoshi Mochizuki, Kazuto Fukuda, Eiji Mita, Yoshimichi Haruna, Atsuo Inoue, Yasuharu Imai …

JOURNAL OF MEDICAL VIROLOGY 83(3) 419-427 2011年3月
α-Galactosylceramide activates antitumor immunity against liver tumor.

Hepatol Res 41(2) 160-169 2011年2月
α-Galactosylceramide activates antitumor immunity against liver tumor.

TATSUMI, T, TAKEHARA, T, MIYAGI, T, SUGIYAMA, T, AKETA, H, SASAKAWA, A, KANTO, T, HIRAMATSU, N, HAYASHI, N

Hepatol Res 41(2) 160-169 2011年2月
alpha-Galactosylceramide activates antitumor immunity against liver tumor

Tomohide Tatsumi, Tetsuo Takehara, Takuya Miyagi, Tsukasa Sugiyama, Hiroshi Aketa, Akira Sasakawa, Tatsuya Kanto, Naoki Hiramatsu, Norio Hayashi

HEPATOLOGY RESEARCH 41(2) 160-169 2011年2月
Annual Review 2011 消化器．C型肝炎・肝がんにおける自然免疫応答．

中外医学社 109-116 2011年
Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection.

Hepatol Res 41(1) 30-38 2011年1月
Indications and limitations for aged patients with chronic hepatitis C in pegylated interferon alfa-2b plus ribavirin combination therapy.

J Hepatol 54, (4), 604-11. 2011年
Ｃ型肝炎・肝がんにおける自然免疫応答．

宮城琢也, 竹原徹郎

Annual Review 2011 消化器. 109-16 2011年
NAFLD病態におけるinvariant NKT細胞が果たす役割.

宮城琢也, 竹原徹郎

消化器内科 52(5) 535-42 2011年
Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection.

TATSUMI, T, TAKEHARA, T, MIYAGI, T, NAKAZURU, S, MITA, E, KANTO, T, HIRAMATSU, N, HAYASHI, N

Hepatol Res 41(1) 30-38 2011年1月
Indications and limitations for aged patients with chronic hepatitis C in pegylated interferon alfa-2b plus ribavirin combination therapy.

OZE, T, HIRAMATSU, N, YAKUSHIJIN, T, MOCHIZUKI, K, OSHITA, M, HAGIWARA, H, MITA, E, ITO, T, FUKUI, H, INUI, Y …

J Hepatol 54 604-11 2011年

もっとみる

講演・口頭発表等

NAFLD病態進展におけるinvariant NKT細胞が果たす役割

第96回日本消化器病学会総会 2010年
Altered interferon-alpha-signaling in natural killer cells in HCV infection.

Osaka University GCOE International Symposium 2010. 2010年
Altered interferon-alpha-signaling in natural killer cells in HCV infection.

Osaka University GCOE International Symposium 2010. 2010年
C型肝炎に対するインターフェロン治療における免疫エフェクター細胞内シグナル伝達解析

第95回日本消化器病学会総会 2009年
非アルコール性脂肪性肝炎病態形成におけるNKT細胞の関与

第45回日本肝臓学会総会 2009年
非アルコール性脂肪性肝炎病態進展におけるInvariant NKT細胞の役割

第51回日本消化器病学会大会、第13回日本肝臓学会大会合同 2009年
Interferon-alpha-signaling in natural killer cells is impaired in chronic hepatitis C virus infection.

The 60th Annual Meeting of the American Association for the Study of Liver Disease. 2009年
Interferon-alpha-signaling in natural killer cells is impaired in chronic hepatitis C virus infection.

The 60th Annual Meeting of the American Association for the Study of Liver Disease. 2009年
ウイルス感染モデルを用いたインターフェロンの免疫細胞内におけるシグナル伝達機構の制御メカニズムに関する基礎的検討

第44回日本肝臓学会総会 2008年
C型肝炎に対するインターフェロン治療における免疫細胞内シグナル伝達解析による治療効果予測の可能性

第50回日本消化器病学会大会、第12回日本肝臓学会大会合同 2008年
Mapping the intracellular signaling pathways regulating type 1 IFN effects during viral infection.

Keystone Symposia, Jaks, Stats and Immunity. 2007年
Access to Signalling Pathways Regulating Type 1 Interferon Effects on Natural Killer Cells During Viral Infection.

第37回日本免疫学会総会・学術集会 2007年
Mapping the intracellular signaling pathways regulating type 1 IFN effects during viral infection.

Keystone Symposia, Jaks, Stats and Immunity. 2007年
STAT REGULATION FOR CONTROLLING NK CELL IFN-GAMMA RESPONSE DURING VIRAL INFECTIONS.

The 93th Annual Meeting of the American Association of Immunologists. 2006年
STAT REGULATION FOR CONTROLLING NK CELL IFN-GAMMA RESPONSE DURING VIRAL INFECTIONS.

The 93th Annual Meeting of the American Association of Immunologists. 2006年
STAT regulation and function in the NK cell IFN-gamma response to acute viral infections.

The 9th Annual Meeting of the Society for Natural Immunity. 2005年
STAT regulation and function in the NK cell IFN-gamma response to acute viral infections.

The 9th Annual Meeting of the Society for Natural Immunity. 2005年
CONCANAVALIN A INJECTION ACTIVATES LIVER INNATE IMMUNE CELLS, NKT CELLS AND NK CELLS, TO PROVOKE AN ANTI-TUMOR EFFECT IN MURINE LIVER.

The 55th Annual Meeting of the American Association for the Study of Liver Disease. 2004年
CONCANAVALIN A INJECTION ACTIVATES LIVER INNATE IMMUNE CELLS, NKT CELLS AND NK CELLS, TO PROVOKE AN ANTI-TUMOR EFFECT IN MURINE LIVER.

The 55th Annual Meeting of the American Association for the Study of Liver Disease. 2004年
CD1D-MEDIATED STIMULATION OF NATURAL KILLER T CELLS ACTIVATES HEPATIC NATURAL KILLER CELLS IN IFN-GAMMA INDEPENDENT PATHWAY AND INDUCES THE ACTIVATION OF ACQUIRED IMMUNITY.

The 54th Annual Meeting of the American Association for the Study of Liver Disease. 2003年

もっとみる

宮城琢也

基本情報

研究キーワード

研究分野

経歴

学歴

受賞

MISC

講演・口頭発表等

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

メニュー