2020年12月8日
Kinetic Resolution of α-Nitrolactones by Catalytic Asymmetric Hydrolysis or Ester–Amide Exchange Reaction
Synlett
- ,
- ,
- ,
- ,
- 巻
- 31
- 号
- 20
- 開始ページ
- 2018
- 終了ページ
- 2022
- 記述言語
- 英語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1055/s-0040-1707303
- 出版者・発行元
- Georg Thieme Verlag {KG}
<title>Abstract</title>
C
1-Symmetric chiral ammonium salt catalysts induced a kinetic resolution of racemic α-nitrolactones through an asymmetric ester–amide exchange reaction. The corresponding amides were obtained with high enantioselectivities and high S (= k
fast/k
slow) values. This reaction system is a useful approach for obtaining carbocyclic quaternary α-nitroamides as chiral building blocks.
C
1-Symmetric chiral ammonium salt catalysts induced a kinetic resolution of racemic α-nitrolactones through an asymmetric ester–amide exchange reaction. The corresponding amides were obtained with high enantioselectivities and high S (= k
fast/k
slow) values. This reaction system is a useful approach for obtaining carbocyclic quaternary α-nitroamides as chiral building blocks.
- リンク情報
- ID情報
-
- DOI : 10.1055/s-0040-1707303
- ISSN : 0936-5214
- eISSN : 1437-2096
- ORCIDのPut Code : 81675032