Sakai Satoshi

J-GLOBAL         Last updated: Sep 11, 2019 at 14:23
 
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Name
Sakai Satoshi
Affiliation
Tsukuba University of Technology

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
Assistant Professor, University of Tsukuba Faculty of Medicine
 

Education

 
 
 - 
1990
School of Medicine, University of Tsukuba
 
 
 - 
1996
Graduate School, Division of Medicine, University of Tsukuba
 

Published Papers

 
Takashi, Miyauchi;Satoshi, Sakai
Peptides   111(SI) 77-88   Jan 2019
Endothelin-1 (ET-1), a 21-amino acid peptide, was initially identified in 1988 as a potent vasoconstrictor and pressor substance isolated from the culture supernatant of porcine aortic endothelial cells. From human genomic DNA analysis, two other ...
Peroxisome proliferator-activated receptor-gamma activators inhibit endothelin-1-related cardiac hypertrophy in rats
Sakai, Satoshi; Miyauchi, Takashi; Irukayama-Tomobe, Yoko; Ogata, Takehiro; Goto, Katsutoshi; Yamaguchi, Iwao
Clinical science (London, England : 1979)   103 Suppl 48 16S-20S   Aug 2002   [Refereed]
Endothelin-1 (ET-1) causes cardiac hypertrophy, and ET receptor antagonists inhibit the development of cardiac hypertrophy in vitro and in vivo. Peroxisome proliferator-activated receptor gamma (PPAR gamma), a member of the family of nuclear recep...
Miyauchi, Takashi; Sakai, Satoshi
Peptides   Epub    Oct 2018
Endothelin-1 (ET-1), a 21-amino acid peptide, was initially identified in 1988 as a potent vasoconstrictor and pressor substance isolated from the culture supernatant of porcine aortic endothelial cells. From human genomic DNA analysis, two other ...
Kimura, Taizo; Tajiri, Kazuko; Sato, Akira; Sakai, Satoshi; Wang, Zheng; Yoshida, Toshimichi; Uede, Toshimitsu; Hiroe, Michiaki; Aonuma, Kazutaka; Ieda, Masaki; Imanaka-Yoshida, Kyoko
Cardiovascular Research   115 614-624   Mar 2019   [Refereed]
[Aims] Tenascin-C (TN-C) is an extracellular matrix protein undetected in the normal adult heart, but expressed in several heart diseases associated with inflammation. We previously reported that serum TN-C levels of myocardial infarction (MI) pat...
Effects of resistance training on arterial compliance and plasma endothelin-1 levels in healthy men
Tagawa, K; Ra, S-G; Kumagai, H; Yoshikawa, T; Yoshida, Y; Takekoshi, K; Sakai, S; Miyauchi, T; Maeda, S
Physiological research   67(Supplementum 1) S155-S166   Jun 2018   [Refereed]
Arterial compliance (AC) is an index of the elasticity of large arteries. Endothelial dysfunction has been reported to result in reduced arterial compliance, which represents increased arterial stiffness. A reduction in AC is elicited by high-inte...

Books etc

 
心臓における生命現象の分子生物学
前田清司;酒井, 俊;宮内, 卓 (Part:Contributor, エンドセリンの心肥大・心不全発症における役割)
東京 メディカルレビュー社   Jan 2001   
循環器疾患モデル動物の病態生理における内因性エンドセリンの役割に関する分子生物学的手法を用いた研究
宮内, 卓;酒井, 俊;山口, 巖;杉下靖郎;寄兼良輔;桜井, 武;後藤勝年.
分子循環器研究会編.「第2回分子循環器研究会講演記録集」,東京:分子循環器研究会   Jan 1994   
心疾患と分子生物
宮内, 卓;酒井, 俊;杉下靖郎 (Part:Supervisor)
臨床成人病   Jan 1995   
心肥大作製法──圧負荷・容量負荷・運動負荷による心肥大
宮内, 卓;酒井, 俊;杉下靖郎 (Part:Supervisor)
実験医学   Jan 1996   
心不全・心肥大の進展における内因性ET-1の関与と受容体遮断薬の効果
宮内, 卓;酒井, 俊;寄兼良輔;後藤勝年;杉下靖郎 (Part:Supervisor)
血管と内皮   Jan 1996   

Conference Activities & Talks

 
Direct Injection of Vascular Cell Adhesion Molecule-1-positive Cardiac Fibroblasts Improves Cardiac Dysfunction after Myocardial Infarction
小菅, 寿徳;中村, 真紀;大矢根, 綾子;田尻, 和子;村越 伸行;酒井 俊;佐藤 明;家田 真樹;青沼 和隆
第83回日本循環器学会学術集会   29 Mar 2019   
MAIR-II deficiency prevents excessive inflammation and fibrosis protecting against cardiac dysfunction post-myocardial infarction
Yonebayashi, Saori;Tajiri, Kazuko;Murakoshi, Nobuyuki;Fumi, Yamagami;Okabe, Yuta;Feng, Duo;Qin, Rujie;Sakai, Satoshi;Shibuya, Akira;Aonuma, Kazutaka;Ieda, Masaki
The 2nd JCS Council Forum on Basic CardioVascular Research   22 Sep 2018   
肺高血圧症の診断と治療 ─実臨床の立場から─ [Invited]
酒井,俊
第2回 長岡 PH Clinical Conference   18 Jul 2018   
静注PGI2開始後肺うっ血をきたした肺高血圧症の1例
大津和也;酒井, 俊;家田真樹
第6回 茨城PAH Clinical Conference   29 Jun 2018   
肺高血圧症の病態と治療の進化 [Invited]
酒井,俊
第27回医学医療系研究発表会   29 Mar 2018   
Gold nanoparticles for imaging vascular inflammation
小菅寿徳;中村真紀;大矢根綾子;田尻和子;村越伸行;酒井 俊;佐藤 明;青沼和隆
第82回日本循環器学会学術集会   23 Mar 2018   
Altered BMP signaling by endothelin-1 to accelerate proliferation of smooth muscle cells
Maruyama, Hidekazu;Sakai, Satoshi;Aonuma, Kazutaka
第82回日本循環器学会学術集会   23 Mar 2018   
The glucagon-like peptide-1 receptor agonist liraglutide suppresses hyopxia-induced pulmonary hypertension in mice partly via recovery of ETB receptor expression
Honda, Junya;Kimura, Taizo;Sakai, Satoshi;Maruyama, Hidekazu;Homma, Satoshi;Miyauchi, Takashi;Aonuma, Kazutaka
第82回日本循環器学会学術集会   23 Mar 2018   
Neutrophil elastase exacerbates myocardial injury after myocardial infarction in mice
Ogura, Yukino;Tajiri, Kazuko;Murakoshi, Nobuyuki;Kimura, Taizo;Xu, Dongzhu;Yonebayashi, Saori;Feng, Duo;Endin, Nokik Stujanna;Honda, Junya;Yamagami, Fumi;Isaka, Yumi;Sakai, Satoshi;Aonuma, Kazutaka;Nogami, Akihiko
第82回日本循環器学会学術集会   23 Mar 2018   
Antagonism of endothelin receptor type B promotes apoptosis in human pulmonary arterial smooth muscle cells
Sakai, Satoshi;Maruyama, Hidekazu;Kimura, Taizo;Honda, Junya;Tajiri, Kazuko;Homma, Satoshi;Miyauchi, Takashi;Aonuma, Kazutaka
第82回日本循環器学会学術集会   23 Mar 2018   
Blockade of endothelin receptor type B promotes apoptosis in human pulmonary arterial smooth muscle cells
Sakai, Satoshi;Maruyama, Hidekazu;Kimura, Taizo;Honda, Junya;Otsu, Kazuya;Homma, Satoshi;Miyauchi, Takashi;Aonuma, Kazutaka
Sixth World Symposium on Pulmonary Hypertension   27 Feb 2018   
Altered BMP signaling by endothelin-1 to accelerate proliferation of smooth muscle cells
Maruyama, Hidekazu;Sakai, Satoshi;Aonuma, Kazutaka
Nice   27 Feb 2018   
The Glucagon-like Peptide-1 Receptor Agonist Ameliorates Hypoxia Induced Pulmonary Hypertension in Mice Model
Honda, Junya;Kimura, Taizo;Sakai, Satoshi;Maruyama, Hidekazu;Homma, Satoshi;Miyauchi, Takashi;Aonuma, Kazutaka
第21回日本心不全学会学術集会   12 Oct 2017   
Glucagon-like peptide-1 receptor agonist liraglutide inhibits hypoxia-induced pulmonary hypertension in mice partly via recovery or ETB receptor expression
Honda, Junya;Kimura, Taizo;Sakai, Satoshi;Maruyama, Hidekazu;Homma, Satoshi;Miyauchi, Takashi;Aonuma, Kazutaka
The 15th International Conference on Endothelin   4 Oct 2017   
Effects of resistance training on central arterial compliance and plasma endothelin-1 levels in young men
Tagawa, Kaname;Ra, Song-Gyu;Kumagai, Hiroshi;Sawano, Yuriko;Yamamoto, Kosaku;Yoshikawa, Toru;Yoshida, Yasuko;Takekoshi, Kazuhiro;Sakai, Satoshi;Miyauchi, Takashi;Maeda, Seiji
The 15th International Conference on Endothelin   4 Oct 2017   
肺動脈性肺高血圧症におけるPGI2系薬剤の位置づけ [Invited]
酒井,俊
第65回日本心臓病学会学術集会   29 Sep 2017   
最新ディーゼルエンジン排気(二次粒子を含む)の曝露が虚血性心疾患に及ぼす影響(1) 曝露チャンバー内の成分分析
細谷純一;荻野浩之;内田里沙;伊藤晃佳;伊藤剛;酒井俊;小林隆弘;坂元和彦;内山巌雄
第58回大気環境学会年会   6 Sep 2017   
最新ディーゼルエンジン排気(二次粒子を含む)の曝露が虚血性心疾患に及ぼす影響(2) SDラットを用いた自律神経系影響の評価
細谷純一;田中睦美;荻野浩之;伊藤剛;酒井俊;小林隆弘;坂元和彦;内山巌雄
第58回大気環境学会年会   6 Sep 2017   
最新ディーゼルエンジン排気(二次粒子を含む)の曝露が虚血性心疾患に及ぼす影響(3) ApoE KOマウスを用いたアテローム性動脈硬化影響の評価
細谷純一;田中睦美;堺温哉;荻野浩之;内田里沙;伊藤晃佳;伊藤剛;酒井俊;小林隆弘;坂元和彦;内山巌雄
第58回大気環境学会年会   6 Sep 2017   
Endothelin-1 modifies BMP signaling pathway to induce cyclin D1 in pulmonary smooth muscle cells.
Mruyama, Hidekazu;Sakai, Satoshi;Aonuma, Kazutaka
Congress of the European-Society-of-Cardiology (ESC) 2017   26 Aug 2017