論文

査読有り
2018年6月1日

Treatment modalities and risk factors associated with refractory neurosensory disturbances of the inferior alveolar nerve following oral surgery: a multicentre retrospective study

International Journal of Oral and Maxillofacial Surgery
  • T. Hasegawa
  • S. I. Yamada
  • N. Ueda
  • S. Soutome
  • M. Funahara
  • M. Akashi
  • S. Furuno
  • H. Miyamoto
  • S. Hayashida
  • R. Amano
  • K. Mori
  • Y. Kojima
  • H. Kurita
  • T. Kirita
  • M. Umeda
  • Y. Shibuya
  • S. Fujita
  • T. Komori
  • Japanese Study Group of Cooperative Dentistry with Medicine (JCDM)
  • 全て表示

47
6
開始ページ
794
終了ページ
801
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.ijom.2017.10.020
出版者・発行元
Churchill Livingstone

Little research has been conducted into hypoesthesia, and no studies have elucidated the risk factors for refractory hypoesthesia and compared treatment modalities. The purpose of this multicentre retrospective cohort study was to investigate the relationships between various risk factors, treatment modalities, and refractory hypoesthesia. Risk factors for refractory hypoesthesia after oral surgery were evaluated using univariate and multivariate analysis. To minimize the selection bias associated with a retrospective data analysis, a propensity score analysis was performed between the medication and non-medication groups (65 sites in each group). Moderate or severe hypoesthesia (odds ratio 13.42) and no or late administration of ATP/vitamin B12 (odds ratio 2.28) were significantly associated with refractory hypoesthesia. In the propensity score analysis, the incidence rate of refractory hypoesthesia in the medication group was lower than that in the non-medication group (P &lt
0.001). This study demonstrated the multivariate relationships between various risk factors, treatment modalities, and refractory hypoesthesia. Moderate or severe hypoesthesia and no or late administration of ATP/vitamin B12 were significantly associated with refractory hypoesthesia. Therefore, clinicians should consider these risk factors and initiate early oral administration of ATP/vitamin B12 in cases of hypoesthesia.

リンク情報
DOI
https://doi.org/10.1016/j.ijom.2017.10.020
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29307502
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85039900564&origin=inward 本文へのリンクあり
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85039900564&origin=inward
ID情報
  • DOI : 10.1016/j.ijom.2017.10.020
  • ISSN : 1399-0020
  • ISSN : 0901-5027
  • eISSN : 1399-0020
  • PubMed ID : 29307502
  • SCOPUS ID : 85039900564

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