KIKUCHI Masanori

J-GLOBAL         Last updated: Dec 12, 2018 at 18:50
 
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Name
KIKUCHI Masanori
Affiliation
National Institute for Materials Science
Job title
Group Leader
Degree
Ph. D.
Other affiliation
Kanazawa Institute of TechnologyOkayama UniversityMeiji University

Research Areas

 

Academic & Professional Experience

 
Apr 2016
 - 
Today
Professor, School of Integrative and Global Majors, University of Tsukuba
 
Apr 2011
 - 
Today
Visiting Professor, Graduate School of Information Science and Technology, Hokkaido University
 
Apr 2006
 - 
Today
Visiting Professor, Okayama University
 
1997
   
 
Researcher, National Institute for Research in
 
1995
   
 
Fellow Researcher, National Institute for Research
 

Education

 
 
   
 
Waseda University, Graduate School of Science and Engineering
 
 
   
 
Department of Mineral Resorces Engineering, School of Science and Engineering Waseda University
 

Awards & Honors

 
Mar 2005
Top 1% cited paper in the field, Thomson (Web of Knowledge)
Winner: Masanori Kikuchi
 
 
1 Commendation for Achievement, Science and Technology
 
 
Agency(2000)
 
 
2 Ichimura Academic Award, The New Technology Development
 
 
Foundation(2000)
 

Published Papers

 
Yasuda Kouichi, Kawano Toshiyuki, Kikuchi Masanori, Aizawa Mamoru, Tsuru Kanji, Tsutsumi Sadami
JOURNAL OF ASIAN CERAMIC SOCIETIES   6(1) 43-53   2018   [Refereed]
Naga Vijaya Lakshmi Manchinasetty, Sho Oshima, Masanori Kikuchi
Journal of Materials Science: Materials in Medicine   28(11)    Nov 2017   [Refereed]
Taira Sato, Masanori Kikuchi, Mamoru Aizawa
Journal of Materials Science: Materials in Medicine   28(3)    Mar 2017   [Refereed]
Takeshi Ogasawara, Masayoshi Uezono, Masayoshi Uezono, Kazuo Takakuda, Masanori Kikuchi, Shoichi Suzuki, Keiji Moriyama
BioMed Research International   2017    Jan 2017
© 2017 Takeshi Ogasawara et al. Subperiosteal bone-bonding devices have been proposed for less invasive treatments in orthodontics. The device is osseointegrated onto a bone surface without fixation screws and is expected to rapidly attain a bone-...
Manchinasetty Naga Vijaya Lakshmi, Sato Taira, Aizawa Mamoru, Madanagurusamy Sridharan, Kikuchi Masanori
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   125(7) 579-583   2017   [Refereed]
Takeuchi Akari, Tsuge Tomohito, Kikuchi Masanori
Ceramics International   42(14) 15376-15382   2016   [Refereed]
Ito Atsuo, Sogo Yu, Yamazaki Atsushi, Aizawa Mamoru, Osaka Akiyoshi, Hayakawa Satoshi, Kikuchi Masanori, Yamashita Kimihiro, Tanaka Yumi, Tadokoro Mika, de Sena Lidia Agata, Buchanan Fraser, Ohgushi Hajime, Bohner Marc
Acta Biomaterialia   25(NA) 347-355   2015   [Refereed]
Bodhak S, Kikuchi M, Sogo Y, Tsurushima H, Ito A, Oyane A
Chemistry Letters   42(9) 1029-1031   2013   [Refereed]
Kikuchi M
Biological & Pharmaceutical Bulletin   36(11) 1666-1669   2013   [Refereed]
Uezono Masayoshi, Takakuda Kazuo, Kikuchi Masanori, Suzuki Shoichi, Moriyama Keiji
Journal of Biomedical Materials Research Part B-Applied Biomaterials   101B(6) 1031-1038   2013   [Refereed]
Sato T, Kochi A, Shirosaki Y, Hayakawa S, Aizawa M, Osaka A, Kikuchi M
Journal of the Ceramic Society of Japan   121(1417) 775-781   2013   [Refereed]
Byung Jae Kang, Hak Hyun Ryu, Sung Su Park, Yoshihisa Koyama, Masanori Kikuchi, Heung Myong Woo, Wan Hee Kim, Oh Kyeong Kweon
Journal of Veterinary Science   13 299-310   Oct 2012
Alternative sources of mesenchymal stem cells (MSCs) for replacing bone marrow (BM) have been extensively investigated in the field of bone tissue engineering. The purpose of this study was to compare the osteogenic potential of canine MSCs derive...
Hidetsugu Maehara, Shinichi Sotome, Shinichi Sotome, Toshitaka Yoshii, Ichiro Torigoe, Yuichi Kawasaki, Yumi Sugata, Yumi Sugata, Masato Yuasa, Masato Yuasa, Masahiro Hirano, Naomi Mochizuki, Masanori Kikuchi, Kenichi Shinomiya, Kenichi Shinomiya, Kenichi Shinomiya, Kenichi Shinomiya, Atsushi Okawa
Journal of Orthopaedic Research   28 677-686   May 2010
Articular cartilage has a limited capacity for self-renewal. This article reports the development of a porous hydroxyapatite/ collagen (HAp/Col) scaffold as a bone void filler and a vehicle for drug administration. The scaffold consists of HAp nan...
Teruaki Yoshida, Teruaki Yoshida, Masanori Kikuchi, Yoshihisa Koyama, Kazuo Takakuda
Journal of Materials Science: Materials in Medicine   21 1263-1272   Apr 2010
The hydroxyapatite/collagen (HAp/Col) sponge with 95% (v/v) porosity was prepared by freeze-drying of a HAp/Col fiber suspension. MG63 cells were seeded onto the HAp/Col sponge and cultured under a pressure/perfusion condition with osteogenic supp...
Ye Eun Byeon, Hak Hyun Ryu, Sung Su Park, Yoshihisa Koyama, Masanori Kikuchi, Wan Hee Kim, Kyung Sun Kang, Oh Kyeong Kweon
Cytotherapy   12 626-636   Jan 2010
Background aims. The aim of this study was to evaluate the paracrine effects of canine umbilical cord blood (cUCB) mesenchymal stromal cells (MSC) mixed with β-tricalcium phosphate (β-TCP) on bone regeneration in ectopic implantation. Methods. β-T...
Ye Eun Byeon, Hak Hyun Ryu, Sung Su Park, Yoshihisa Koyama, Masanori Kikuchi, Min Soo Seo, Wan Hee Kim, Kyung Sun Kang, Oh Kyeong Kweon
Tissue Engineering and Regenerative Medicine   6 833-839   Jun 2009
The objective of this study is to evaluate the effect of mixtures of β-tricalcium phosphate(β-Ca3(PO4)2, β-TCP) granules with canine allogenic umbilical cord blood derived mesenchymal stem cells(UCB-MSC) and their lysates on bone formation. The mi...
Akio Tsuchiya, Akio Tsuchiya, Shinichi Sotome, Yoshinori Asou, Masanori Kikuchi, Yoshihisa Koyama, Tetsuro Ogawa, Junzo Tanaka, Kenichi Shinomiya, Kenichi Shinomiya, Kenichi Shinomiya
Journal of Medical and Dental Sciences   55(1) 91-99   Mar 2008
A porous hydroxyapatite/collagen composite (HAp/Col) was developed that consists of hydroxyapatite nanocrystals and atelocollagen. In this study, cylindrical (diameter: 5 mm, height: 3 mm) porous HAp/Col implants with different pore sizes (diamete...
Byung Jun Jang, Ye Eun Byeon, Ji Hey Lim, Hak Hyun Ryu, Hee Kim Wan, Yoshihisa Koyama, Masanori Kikuchi, Kyung Sun Kang, Oh Kyeong Kweon
Journal of Veterinary Science   9 389-395   Jan 2008
This study was performed to evaluate the osteogenic effect of allogenic canine umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) mixed with beta-tricalcium phosphate (β-TCP) in orthotopic implantation. Seven hundred milligrams of β-TC...
Yoshihisa Koyama, Masanori Kikuchi, Kazuya Edamura, Katsuyoshi Nagaoka, Shigeo Tanaka, Junzo Tanaka, Kazuo Takakuda
Journal of Nanoscience and Nanotechnology   7(3) 859-861   Mar 2007
Guided Bone Regeneration (GBR) is a method for bone tissue regeneration. In this method, membranes are used to cover bone defects and to block the invasion of the surrounding soft tissues. It would provide sufficient time for the osteogenic cells ...
Kazuo Takakuda, Kazuo Takakuda, Yoshihisa Koyama, Yoshihisa Koyama, Hiroko N. Matsumoto, Noriaki Shirahama, Kazumi Akita, Daisuke Shoji, Tetsuro Ogawa, Masanori Kikuchi, Junzo Tanaka
Journal of Nanoscience and Nanotechnology   7(3) 738-741   Mar 2007
Two new bioabsorbable inorganic/organic composite materials were developed for bone regeneration. One material used was β-TCP/PLGC in which poly(L-lactide-co-glycolide-co-ε-caprolactone) and β-tricalcium phosphate were used as the matrix and fille...
Taehoon Oh, Md Mizanur Rahman, Ji Hey Lim, Mi Sun Park, Dae Yong Kim, Jung Hee Yoon, Wan Hee Kim, Masanori Kikuchi, Junzo Tanaka, Yoshihisa Koyama, Oh Kyeong Kweon
Journal of Veterinary Science   7 73-77   Jan 2006
This study was performed to evaluate the effect of betatricalcium phosphate and poly L-lactide-co-glyeolide-co-epsilon-caprolactone (TCP/PLGC) membrane in the repair of partial bone defects in canine proximal humerus. Three adult mixed-breed dogs ...
Soichiro Itoh, Soichiro Itoh, Masanori Kikuchi, Yosihisa Koyama, Hiroko N. Matumoto, Kazuo Takakuda, Kenichi Shinomiya, Junzo Tanaka
Bio-Medical Materials and Engineering   15 29-41   Jul 2005
A hydroxyapatite/type I collagen (HAp/Col) composite, aligning hydroxyapatite nano-crystals along collagen molecules, has been synthesized. The biocompatibility, osteoconductivity and efficacy as an rhBMP-2 carrier of this novel biomaterial implan...
Masanori Kikuchi, Yoshihisa Koyama, Takeki Yamada, Yukari Imamura, Takao Okada, Noriaki Shirahama, Kazumi Akita, Kazuo Takakuda, Junzo Tanaka
Biomaterials   25 5979-5986   Dec 2004
To create biodegradable and thermoplastic materials for guided bone regeneration, GBR, and guided tissue regeneration, GTR, membranes, composites of β-tricalcium phosphate, TCP, and biodegradable polyesters, poly (L-lactide-co-glycolide-co-ε-capro...
Masanori Kikuchi, Masanori Kikuchi, Toshiyuki Ikoma, Toshiyuki Ikoma, Soichiro Itoh, Soichiro Itoh, Hiroko N. Matsumoto, Hiroko N. Matsumoto, Yoshihisa Koyama, Yoshihisa Koyama, Kazuo Takakuda, Kazuo Takakuda, Kenichi Shinomiya, Kenichi Shinomiya, Junzo Tanaka, Junzo Tanaka
Composites Science and Technology   64 819-825   May 2004
To fabricate an artificial bone material having bone-like nanostructure and chemical composition, a composite composed of hydroxyapatite (HAp) and collagen was synthesized under a biomimetic condition through the self-organization mechanism betwee...
Shinichi Sotome, Toshimasa Uemura, Toshimasa Uemura, Masanori Kikuchi, Masanori Kikuchi, Jiani Chen, Soichiro Itoh, Soichiro Itoh, Junzo Tanaka, Junzo Tanaka, Tetsuya Tateishi, Tetsuya Tateishi, Tetsuya Tateishi, Kenichi Shinomiya, Kenichi Shinomiya
Materials Science and Engineering C   24 341-347   Apr 2004
Recently, hydroxyapatite/collagen (HAp/Col) nanocomposites incorporated into bone remodeling processes have been developed. Because bone tissue reaction to the composites is obviously suitable for bone tissue engineering, a novel HAp/Col-alginate ...
M. Kikuchi, M. Kikuchi, T. Ikoma, T. Ikoma, D. Syoji, H. N. Matsumoto, Y. Koyama, Y. Koyama, S. Itoh, S. Itoh, K. Takakuda, K. Takakuda, K. Shinomiya, K. Shinomiya, J. Tanaka, J. Tanaka
Key Engineering Materials   254-256 561-564   Jan 2004
Elastic porous bodies were fabricated from the self-organized hydroxyapatite/collagen nanocomposite fibers by lyophilization with the use of collagen as a binder. The porous bodies obtained rapidly absorbed water droplet on them and composed of in...
Soichiro Itoh, Soichiro Itoh, Masanori Kikuchi, Yoshihisa Koyama, Kazuo Takakuda, Kenichi Shinomiya, Junzo Tanaka
Cell Transplantation   13 451-461   Jan 2004
The effect of cross-linking of a hydroxyapatite/collagen (HA/Col) nanocomposite, in which HA nanocrystals and collagen fibers are aligned like natural bone by a self-organization mechanism between HA and collagen in vitro, on mechanical properties...
Masanori Kikuchi, Masanori Kikuchi, Hiroko N. Matsumoto, Hiroko N. Matsumoto, Takeki Yamada, Yoshihisa Koyama, Kazuo Takakuda, Kazuo Takakuda, Junzo Tanaka, Junzo Tanaka
Biomaterials   25 63-69   Jan 2004
To control the mechanical properties and biodegradability of self-organized hydroxyapatite/collagen (HAp/Col) nanocomposites, cross-linkage was introduced into the composites with glutaraldehyde (GA). The HAp/Col composite suspensions, prepared by...
Kazushi Ohta, Masanori Kikuchi, Junzo Tanaka
Chemistry Letters   32 646-647   Jul 2003
Hydroxyapatite (HAp) sintered bodies with c axis orientation were fabricated using c axis oriented plate-like HAp aggregates synthesized as described by us. The results of scanning electron microscopy and X-ray diffractometry indicated that the pl...
Pao Li Wang, Kiyoshi Ohura, Takeo Fujii, Mari Oido-Mori, Yusuke Kowashi, Masanori Kikuchi, Yasushi Suetsugu, Junzo Tanaka
Biochemical and Biophysical Research Communications   305 970-973   Jun 2003
In the inflammatory gingival tissues of patients with periodontitis, cytokines such as interleukin (IL)-1α, IL-1β, IL-6, IL-8, and tumor necrosis factor (TNF)-α have been detected. Gingival fibroblasts are the major constituents of gingival tissue...
Yoshihisa Koyama, Masanori Kikuchi, Takeki Yamada, Tomohiro Kanaya, Hiroko N. Matsumoto, Kazuo Takakuda, Hiroo Miyairi, Junzo Tanaka
JSME International Journal, Series C: Mechanical Systems, Machine Elements and Manufacturing   46 1409-1416   Jan 2003
Guided Bone Regeneration (GBR) is a method for bone tissue regeneration. In this method, membranes are used to cover bone defects and to block the invasion of the surrounding soft tissues. It would provide sufficient time for the osteogenic cells ...
Toshimasa Uemura, Toshimasa Uemura, Toshimasa Uemura, Jian Dong, Yichao Wang, Yichao Wang, Hiroko Kojima, Hiroko Kojima, Takashi Saito, Daisuke Iejima, Masanori Kikuchi, Masanori Kikuchi, Junzo Tanaka, Junzo Tanaka, Tetsuya Tateishi, Tetsuya Tateishi, Tetsuya Tateishi
Biomaterials   24 2277-2286   Jan 2003
The transplantation of cultured bone cells is expected to become a candidate for bone regeneration therapy. For the clinical application of this therapy, there remain several problems to be overcome, for example, the improvements of scaffolds and ...
Masanori Kikuchi, Masanori Kikuchi, Yoshihisa Koyama, Kazuo Takakuda, Hiroo Miyairi, Noriaki Shirahama, Junzo Tanaka
Journal of Biomedical Materials Research   62 265-272   Nov 2002
Novel composites of bioactive β-tricalcium phosphate [Ca3(PO4)2] and biodegradable copolymerized poly-L-lactide (CPLA) were prepared by a heat-kneading method. The mechanical and chemical changes of the composites were evaluated in vitro by soakin...
Soichiro Itoh, Masanori Kikuchi, Kazuo Takakuda, Katsuyoshi Nagaoka, Yoshihisa Koyama, Junzo Tanaka, Kenichi Shinomiya, Kenichi Shinomiya
Journal of Biomedical Materials Research   63 507-515   Oct 2002
A hydroxyapatite/type I collagen (HAp/Col) composite, aligning hydroxyapatite nanocrystals along collagen molecules, has been prepared. The biocompatibility, osteoconductive activity, and efficacy as a carrier of rhBMP-2 of this novel biomaterial ...
M. C. Chang, M. C. Chang, T. Ikoma, T. Ikoma, M. Kikuchi, M. Kikuchi, J. Tanaka, J. Tanaka
Journal of Materials Science: Materials in Medicine   13 993-997   Oct 2002
Hydroxyapatite(HAp)/collagen nanocomposites were prepared by a coprecipitation method controlling the degree of cross-linkage between collagen molecules using glutaraldehyde. The precipitates filtered were dried in a freeze drier or naturally drie...
Kazushi Ohta, Masanori Kikuchi, Junzo Tanaka, Hiroshi Eda
Chemistry Letters   894-895   Sep 2002
The c axes oriented hydroxyapatite (HAp) aggregates were synthesized by the hydrolysis of CaHPO4·2H2O (DCPD) at 100°C in 10 mass% NaOH solution. The HAp was of a plate-like form resembling DCPD. The X-ray diffraction pattern shows that the relativ...
Jian Dong, Jian Dong, Toshimasa Uemura, Masanori Kikuchi, Junzo Tanaka, Tetsuya Tateishi
Bio-Medical Materials and Engineering   12 203-209   Aug 2002
In this study, we hypothesize that loading more marrow-derived mesenchymal stem cells (MSCs) into porous material by using a low-pressure system during subculture, creating a composite which combines MSCs and a novel mechanical reinforced porous h...
Soichiro Itoh, Masanori Kikuchi, Yosihisa Koyama, Kazuo Takakuda, Kenichi Shinomiya, Junzo Tanaka
Biomaterials   23 3919-3926   Jul 2002
Hydroxyapatite/collagen (HAp/Col) composites having a bone-like nanostructure were synthesized and shaped into implants. This study was designed to develop an artificial vertebra system using this novel implant for anterior fusion of the cervical ...
Pao Li Wang, Mari Oido-Mori, Takeo Fujii, Yusuke Kowashi, Masanori Kikuchi, Yasushi Suetsugu, Junzo Tanaka, Yasutaka Azuma, Mitsuko Shinohara, Kiyoshi Ohura
Japanese Journal of Pharmacology   89 176-183   Jan 2002
The lipopolysaccharide (LPS) released by Porphyromonas gingivalis, a Gram-negative bacterium found in the periodontal pockets of patients with periodontitis, induces bone resorbing activity in vivo. We previously showed that a receptor for LPS on ...
P. L. Wang, M. Oido-Mori, T. Fujii, Y. Kowashi, M. Kikuchi, Y. Suetsugu, J. Tanaka, Y. Azuma, M. Shinohara, K. Ohura
Biochemical and Biophysical Research Communications   288 863-867   Nov 2001
Porphyromonas gingivalis (P. gingivalis) is implicated in the initiation and progression of periodontitis. Human gingival fibroblasts (HGFs) are the major constituent of gingival connective tissue. P. gingivalis or its components such as lipopolys...
Jian Dong, Jian Dong, Toshimasa Uemura, Toshimasa Uemura, Toshimasa Uemura, Hiroko Kojima, Hiroko Kojima, Masanori Kikuchi, Masanori Kikuchi, Junzo Tanaka, Junzo Tanaka, Tetsuya Tateishi, Tetsuya Tateishi, Tetsuya Tateishi
Materials Science and Engineering C   17 37-43   Nov 2001
Recently, synthetic porous hydroxyapatite (HA) has attracted a great deal of attention as a bone graft substitute in the field of tissue engineering. Combining with bone marrow-derived osteoblasts (BMO), bone formation has been confirmed in vivo a...
Jian Dong, Hiroko Kojima, Hiroko Kojima, Toshimasa Uemura, Toshimasa Uemura, Masanori Kikuchi, Tetsuya Tateishi, Junzo Tanaka, Junzo Tanaka, Junzo Tanaka
Journal of Biomedical Materials Research   57 208-216   Nov 2001
Biosynthetic bone grafts are considered to contain one or more of three critical components: osteoprogenitor cells, an osteoconductive matrix, and osteoinductive growth factors. The basic requirements of the scaffold material are biocompatibility,...
Masanori Kikuchi, Soichiro Itoh, Shizuko Ichinose, Kenichi Shinomiya, Junzo Tanaka
Biomaterials   22(13) 1705-1711   Jul 2001
When bone is lost due to injury and/or illness, the defects are generally filled with natural bone because artificial bone materials have problems of bioaffinity. However, natural bone also has supply and infection problems. If an artificial mater...
M. C. Chang, M. C. Chang, T. Ikoma, T. Ikoma, M. Kikuchi, M. Kikuchi, J. Tanaka, J. Tanaka
Journal of Materials Science Letters   20(13) 1199-1201   Jul 2001   [Refereed]
Glutaraldehyde was used as a crosslinkage agent for the preparation of porous hydroxyapatite/collagen nanocomposites. Hydroxyapatites (HAp) are the suitable bone subsitutes that gives biocompatible, bioactive, biodegradable and osteoconductive pro...
S. Itoh, K. Takakuda, S. Ichinose, M. Kikuchi, K. Schinomiya
Journal of Reconstructive Microsurgery   17 115-123   Mar 2001
A silicone tube (S-tube) was packed with CPLA (copolymer of poly-L-lactide) fibers (S-tube+CPLA) or collagen fibers (S-tube+fiber). Two types of tube were prepared from a collagen sheet (Col-tube) and a bioabsorbable atelocollagen membrane for gui...
Soichiro Itoh, Masanori Kikuchi, Kazuo Takakuda, Yoshihisa Koyama, Hiroko N. Matsumoto, Shizuko Ichinose, Junzo Tanaka, Toshiyuki Kawauchi, Kenichi Shinomiya
Journal of Biomedical Materials Research   54 445-453   Mar 2001
A hydroxyapatite/type I collagen (HAp/Col) composite, in which the hydroxyapatite nanocrystals align along the collagen molecules, has been prepared. The biocompatibility, osteoconductive activity, and efficacy as a carrier of recombinant human bo...
DONG J, KOJIMA H, UEMURA T, et al.
BONE   28(5) S153   2001   [Refereed]
Masanori Kikuchi, Junzo Tanaka
Journal of the Ceramic Society of Japan   108 642-645   Jan 2000
For the development of a novel biodegradable membrane useful for surgical operations, the chemical inter-action between β-tricalcium phosphate (TCP) and copolymerized poly-L-lactide (CPLA) in the TCP/CPLA composites was investigated by Fourier-tra...
Pao Li Wang, Pao Li Wang, Shinya Shirasu, Mitsuki Shinohara, Michiharu Daito, Masanori Kikuchi, Yasushi Suetsugu, Jyunzo Tanaka, Kiyoshi Ohura
Medical Science Research   27 311-313   Jun 1999
Our previous research showed that CD14 functions as a receptor for the lipopolysaccharides (LPS) of Porphyromonas gingivalis on human gingival fibroblasts (HGF), leading to cellular activation. This suggested that interleukin-6 (IL-6) derived from...
Masanori Kikuchi, Masanori Kikuchi, Junzo Tanaka, Yoshihisa Koyama, Kazuo Takakuda
Journal of Biomedical Materials Research   48 108-110   Apr 1999
Thermoplastic polymers filled with a ceramic powder (here described as a 'composite') of β-tricalcium phosphate (TCP) and copoly-L-lactide (CPLA) was prepared by a heat-kneading method. The TCP/CPLA composite obtained had a three-point bending str...
Masanori Kikuchi, Sung Baek Cho, Junzo Tanaka, Yoshihisa Koyama, Yoshihisa Koyama, Takayuki Kobayashi, Takayuki Kobayashi, Kazuo Takakuda, Kazuo Takakuda, Masaru Akao, Masaru Akao
Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy   45 36-40   Jan 1998
Thermoplastic composites of β-tricalcium phosphate (TCP) / copolymerized poly-L-lactide (CPLA) were prepared by a heat kneading method and evaluated by XRD, FT-IR, three-point bending strength test and SEM. The composites were white and no structu...
M. Kikuchi, Y. Suetsugu, J. Tanaka, M. Akao
Journal of Materials Science: Materials in Medicine   8 361-364   Jun 1997
New artificial bone materials were prepared using calcium phosphates, hydroxyapatite and β-tricalicum phosphate, and copoly-L-lactide, CPLA. Calcium phosphate powder and CPLA were mixed at 453 K for 10 min with various mixing ratios. Scanning elec...
Masanori Kikuchi, Astsushi Yamazaki, Masaru Akao, Hideki Aoki
Bio-Medical Materials and Engineering   6 405-413   Dec 1996
Barium hydroxyapatite (Ba10(PO4)6(OH)2, Ba-HAp) was synthesized by a wet method using Ba(OH)2 · 8H2O and (NH4)2HPO4 as starting materials. The Ba-HAp obtained had a Ba/P atomic ratio of 1.76 and contained CO3 groups. The Ba-HAp was sintered at 107...
Masanori Kikuchi, Atsushi Yamazaki, Ryohei Otsuka, Masaru Akao, Hideki Aoki
Journal of Solid State Chemistry   113 373-378   Jan 1994
Single crystals of Sr-substituted hydroxyapatite, (Ca9.42Sr0.18H0.8(PO4)6(OH)2, up to 0.2 × 0.2 × 5 mm3maximum size were grown hydrothermally from calcium hydrogenphosphate (CaHPO4) and strontium hydrogenphosphate (SrHPO4) in a long tube-type auto...
Masanori Kikuchi, Atsushi Yamazaki, Masaru Akao, Hideki Aoki Cytotoxicity of Symthetic Barium Hydroxyapatite
Bio-Med. Mater. Eng. 6, 405-413, 1996   
Masanori Kikuchi, Atsushi Yamazaki, Masaru Akao, Hideki Aoki Thermal Changes in Synthetic Deuterioxyapatite
Mineralogical J. 18, 79-86, 1996   

Misc

 
Arief Cahyanto, Kanji Tsuru, Kunio Ishikawa, Masanori Kikuchi
Key Engineering Materials   720 167-172   Jan 2017
© 2017 Trans Tech Publications. The combination of tetracalcium phosphate (TTCP; Ca4(PO4)2O) and dicalcium phosphate anhydrous (DCPA; CaHPO4) which are known as one system of apatite cements already used in the medical and dental application. In s...
Masanori Kikuchi
Biological and Pharmaceutical Bulletin   36 1666-1669   Nov 2013
Our group has succeeded to synthesize material with bone-like nanostructure and bone-like inorganic and organic composition via self-organization mechanism between them using simultaneous titration method under controlled pH and temperature. The h...
Yoshiyuki Yokogawa, Satoshi Hayakawa, Hiroaki Imai, Masakazu Kawashita, Toshiki Miyazaki, Masanori Kikuchi, Masahiro Yoshimura, Astushi Nakahira
Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan   121    Sep 2013
Subhadip Bodhak, Subhadip Bodhak, Subhadip Bodhak, Masanori Kikuchi, Ayako Oyane, Yu Sogo, Hideo Tsurushima, Atsuo Ito
Key Engineering Materials   529-530 490-494   Jan 2013
Calcium phosphate (CaP) coating is an effective technique for surface functionalization of biomaterials. The objective of our research is to prepare calcium phosphate (CaP) coatings on a hydroxyapatite/collagen (HAp/Col) nanocomposite and subseque...
Akinori Kochi, Akinori Kochi, Masanori Kikuchi, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka
Key Engineering Materials   493-494 689-692   Jan 2012
Injectable hydroxyapatite/collagen nanocomposite (HAp/Col) artificial bone was prepared utilizing gelation of sodium alginate (Na-Alg). Mass ratio of the HAp/Col powder, with or without Ca adsorption treatment and Na-Alg (80-120, 300-400, 500-600 ...
S. Bodhak, M. Kikuchi, A. Oyane, Y. Sogo, H. Tsurushima, A. Ito
Key Engineering Materials   493-494 126-131   Jan 2012
Hydroxyapatite/collagen (HAp/Col) nanocomposites with bone-like self-organized nanostructure show excellent bioactivity in vivo. However, they show quite high absorbability for cationic ions and lower culture medium ionic concentrations which adve...
Masanori Kikuchi, Atsushi Irie
Key Engineering Materials   396-398 449-452   Feb 2009
Osteoclast differentiation of bone marrow cells on hydroxyapatite/collagen self-organized bone-like nanocomposite (HAp/Col) disk in vitro was evaluated by coculture of mouse bone marrow cells with mouse osteoblasts with or without addition of oste...
Masanori Kikuchi, Yoshihisa Koyama, Kazuo Takakuda, Shigeo Tanaka
8th World Biomaterials Congress 2008   1 517   Dec 2008
Yulin Li, Masanori Kikuchi
8th World Biomaterials Congress 2008   1 518   Dec 2008
T. Yoshida, T. Yoshida, I. Mizuno, M. Kikuchi, Y. Koyama, K. Takakuda
Key Engineering Materials   361-363 II 1079-1082   Jan 2008
The bone-like self-organized hydroxyapatite/collagen (HAp/Col) nanocomposite sponge was prepared from HAp/Col nanocomposite fibers. We analyzed osteogenic activity of human osteoblastic MG63 cells in the HAp/Col sponge under pressure/perfusion cul...
Yulin Li, Masanori Kikuchi
Key Engineering Materials   361-363 I 415-418   Jan 2008
Biocompatible and water-soluble fibers (sodium carboxymethyl cellulose (CMC)) were fabricated via a wet-spinning method. The CMC fibers/ polymethyl methacrylate (PMMA) mixtures and CMC fibers/Poly (L-lactide-co-glycolide-co- ε-caprolactone) (PLGC)...
Masanori Kikuchi
Key Engineering Materials   361-363 I 431-434   Jan 2008
Effect of osteogenic activities of MG63 on the HAp/Col membrane was examined at day 10 and 14 by reverse-transcript and real-time polymerase chain reactions. Osteogenic activities of MG63 were upregulated by culture them on the HAp/Col membrane in...
Masanori Kikuchi, Yasushi Suetsugu, Yoshihisa Koyama, Shinichi Sotone, Saoichiro Itoh, Kazuo Takakuda, Kenichi Shinomiya, Kazuya Edamura, Katsuyoshi Nagaoka, Shigeo Tanaka
Biomaterials in Asia: In Commemoration of the 1st Asian Biomaterials Congress, Tsukuba, Japan, 6 - 8 December 2007   327-342   Jan 2008
Masanori Kikuchi, Junzo Tanaka
Key Engineering Materials   342-343 277-280   Apr 2007
Biomaterials Center is composed of five groups and collaborate each other to examine interdisciplinary fields of biomaterials. In the ceramics-based biomaterials research, we have been developing three novel bone regeneration materials, i.e., high...
Masatsugu Shimomura, Masatsugu Shimomura, Masatsugu Shimomura, Masatsugu Shimomura, Masatsugu Shimomura, Kuniharu Ijiro, Masanori Kikuchi, Junzo Tanaka, Junzo Tanaka
Journal of Nanoscience and Nanotechnology   7    Mar 2007
T. Yoshida, T. Yoshida, M. Kikuchi, Y. Koyama, K. Takakuda
Key Engineering Materials   330-332 I 317-320   Jan 2007
The purpose of this study is to analyze osteogenic activity of human osteoblastic MG63 cells on the bone-like self-organized hydroxyapatite/collagen (HAp/Col) nanocomposite sponge cultured by a pressure/perfusion technique using collagen sponge as...
Masanori Kikuchi
Key Engineering Materials   330-332 I 313-316   Jan 2007
The hydroxyapatite/collagen (HAp/Col) nanocomposite membrane was prepared from the HAp/Col nanocomposite fibers. The HAp/Col membrane crosslinked by a vacuum heating showed 14±2 (dry) and 1.0±0.1 (wet) MPa in tensile strengths that were enough str...
Sang Ho Ye, Masanori Kikuchi
Key Engineering Materials   330-332 II 1049-1052   Jan 2007
To develop a bioactive inorganic/organic composite matrix material, which could be applied in a proactive bone tissue regeneration therapy, a composite of ricalcium phosphate (TCP), and biodegradable poly-(L-lactide-co-glycolide-co-e- caprolactone...
Y. Suetsugu, Y. Hotta, M. Iwasashi, M. Sakane, M. Kikuchi, T. Ikoma, T. Higaki, N. Ochiai, J. Tanaka
Key Engineering Materials   330-332 II 1003-1006   Jan 2007
Porous ceramics of hydroxyapatite was fabricated utilizing the crystal growth of thin ice columns parallel to one another in gelatin gel containing hydroxyapatite nanoparticles. The obtained ceramics possessed unidirectional pore channels with a p...
Kazushi Ohta, Masanori Kikuchi, Toshiyuki Ikoma, Shunji Yunoki, Akira Monkawa, Junzo Tanaka
Key Engineering Materials   309-311 I 77-80   Apr 2006
Mesoporous HAp aggregates were composed of needle-like crystals that were aligned to the c-axes direction perpendicular to the flat surface of plate-like aggregates. The pore size distributions of the HAp aggregates increased with increasing heat ...
Shunji Yunoki, Toshiyuki Ikoma, Akira Monkawa, Kazushi Ohta, Masanori Kikuchi, Junzo Tanaka
Key Engineering Materials   309-311 II 1091-1094   Apr 2006
Hydroxyapatite/collagen (HAp/Col) composite scaffold with unidirectionally elongated pores (scaffold-U) was fabricated by the unidirectional solidification with ice growth and subsequent freeze-dry process. The pore architecture in the composite w...
Shinichi Sotome, Shinichi Sotome, Hisaya Orii, Hisaya Orii, Masanori Kikuchi, Toshiyuki Ikoma, Akimasa Ishida, Junzo Tanaka, Kenichi Shinomiya, Kenichi Shinomiya, Kenichi Shinomiya
Key Engineering Materials   309-311 II 977-980   Apr 2006
Transplantation surgeries of autologous bone require a second surgery with inherent risks. To avoid these risks, we developed a multi porous implant of hydroxyapatite/collagen composite with desirable biophysical properties (flexibility, elasticit...
S. Yunoki, T. Ikoma, A. Monkawa, K. Ohta, M. Kikuchi, S. Sotome, K. Shinomiya, J. Tanaka
Materials Letters   60(8) 999-1002   Apr 2006
The porous hydroxyapatite/collagen (HAp/Col = 80/20 in weight ratio) composite with unique three-dimensional pore structures was fabricated by the control of ice crystal growth using the liquid N2as a cooling medium and subsequent freeze-dry proce...
Shunji Yunoki, Toshiyuk Ikoma, Akira Monkawa, Masanori Kikuchi, Junzo Tanaka
Materials Research Society Symposium Proceedings   873 154-159   Dec 2005
Self-organized hydroxyapatite /collagen (HAp/Col) nanocomposite was synthesized by a co-precipitated method. The porous HAp/Col nanocomposites with unidirectional and interconnected pores with approximately 20μm in size were prepared by a facile m...
Y. Suetsugu, T. Ikoma, M. Kikuchi, J. Tanaka
Key Engineering Materials   288-289 525-528   Dec 2005
Single crystals of AB-type carbonate apatite were grown by a CaCO 3-Na2CO3 flux method under high pressure of Ar gas. The crystals obtained were hexagonal prismatic elongated along the c-axis with the length of 2mm and the diameter of 0.3mm at a m...
Tetsunari Nishikawa, Tetsunari Nishikawa, Kazuya Masuno, Kazuya Tominaga, Yoshihisa Koyama, Takeki Yamada, Kazuo Takakuda, Masanori Kikuchi, Masanori Kikuchi, Junzo Tanaka, Junzo Tanaka, Akio Tanaka
Implant Dentistry   14(3) 252-260   Sep 2005
The purpose of this study was to evaluate a biodegradable hydroxyapatite/collagen composite and to examine the use of the calcium ion contained for bone formation and growth. Surgical holes were prepared in the femora and tibiae of beagle dogs, an...
Masanori Kikuchi
Chemical Processing of Ceramics, Second Edition   613-628   Jan 2005
Kazushi Ohta, Masanori Kikuchi, Junzo Tanaka
Key Engineering Materials   254-256 15-18   Jan 2004
Hydroxyapatite (HAp) crystals were synthesized by the hydrolysis of CaHPO4·2H2O in a NaOH solution. Their aggregates formed by hydrolysis at 100°C were composed of needle-like crystals which aligned in c-axis orientation perpendicular to the wide ...
M. Kikuchi, M. Kikuchi, S. Itoh, S. Itoh, H. N. Matsumoto, H. N. Matsumoto, Y. Koyama, Y. Koyama, K. Takakuda, K. Takakuda, K. Shinomiya, K. Shinomiya, J. Tanaka, J. Tanaka
Key Engineering Materials   240-242 567-570   Apr 2003
Fibrillogenesis of hydroxyapatite(HAp)/collagen(Col) self-organized composites was examined at several synthesis conditions. The measurement of calcium concentration in a reaction vessel during the synthesis indicated that the presence of collagen...
Kazushi Ohta, Masanori Kikuchi, Junzo Tanaka, Hiroshi Eda
Key Engineering Materials   240-242 517-520   Apr 2003
The aggregates of c-axes oriented hydroxyapatite (HAp) crystallites were synthesized by the hydrolysis of CaHPO4·2H2O (DCPD) at 100 °C in 10mass% of NaOH solution. The HAp aggregate was of a plate-like form resembling DCPD. The measurements of X-r...
M. Kikuchi, T. Taguchi, H. N. Matsumoto, K. Takakuda, J. Tanaka
Key Engineering Materials   218-220 449-452   Feb 2002
To control the mechanical properties and biodegradability of self-organized hydroxyapatite/collagen (HAp/Col) nanocomposites, cross-linkage was introduced into the composites with three different reagents: i.e. glutaraldehyde, water-soluble carbod...
S. Sotome, T. Uemura, M. Kikuchi, S. Itoh, J. Tanaka, M. Takahashi, T. Tateishi, K. Shinomiya
Key Engineering Materials   218-220 153-156   Feb 2002
We had studied HAp/Col by conventional in-vitro methods but met with problems. In this study, we introduced some of these challenges in the in-vitro tests for HAp/Col composite. Osteoblastic primary cells were cultured from rat bone marrow. After ...
M. Kikuchi, Y. Koyama, K. Takakuda, H. Miyairi, J. Tanaka
Key Engineering Materials   192-195 677-680   Jan 2001
In order to realize easy handling films, novel composites of β-tricalcium phosphate (TCP) and poly-(lactide-glycolic acid-ε-caprolactone) (PLGC) having a softening temperature of about 40°C were prepared by a heat-kneading method. The composite pr...
Masanori Kikuchi, Junzo Tanaka, Soichiro Itoh, Shizuko Ichinose, Yoshihisa Koyama, Kazuo Takakuda, Katsuyoshi Nagaoka, Shigeo Tanaka
Materials Research Society Symposium - Proceedings   599 51-53   Dec 2000
Nanocomposites of hydroxyapatite (HAp) and collagen (Col) were prepared by a biomimetic coprecipitation method under controlled pH and temperature. Transmission electron micrographs showed that the c-axis of HAp nanocrystals aligned along collagen...
田中順三, 菊池正紀, 佐藤公泰, 生駒俊之, 山口勇
物質・材料の自己組織化機構の解析と制御に関する研究(第1期)成果報告書 平成8-10年度   107-121   2000
菊池正紀, 田中順三, 伊藤聡一郎
顎顔面バイオメカニクス学会誌   5(1) 33-34   Dec 1999
高久田和夫, 小山富久, 松本裕子, 宮入裕夫, 菊池正紀, 田中順三, 永岡勝好, 小坂俊文, 田中茂男
顎顔面バイオメカニクス学会誌   5(1) 37-38   Dec 1999
井村浩一, 上本英雄, 田中順三, 菊池正紀, 山崎拓
日本バイオマテリアル学会大会予稿集   21st 70   Nov 1999
高久田和夫, 小山富久, 松本裕子, 宮入裕夫, 菊池正紀, 田中順三
バイオエンジニアリング学術講演会・秋季セミナー講演論文集   10th 23-24   Sep 1999
田中順三, 菊池正紀
表面科学   20(9) 600-606   Sep 1999
田中順三, 菊池正紀
セラミックス   34(7) 543-546   Jul 1999
菊池正紀, 田中順三, 小山富久, 高久田和夫
粉体粉末冶金協会講演概要集   1999 181   Jun 1999
菊池正紀, 末次寧, 田中順三, 伊藤聡一郎, 四宮謙一, 市野瀬志津子, 平岡陽介, 万代佳宣, 中谷伸一
インテリジェント材料シンポジウム講演要旨集   8th 44-45   Mar 1999
菊池正紀, 藤沢章, 服部昌晃
セラミックス   34(1) 42-46   Jan 1999
Sung Baek Cho, Masanori Kikuchi, Yasushi Suetsugu, Junzo Tanaka
Key Engineering Materials   802-805   Dec 1997
Artificial bone materials are required to form bonelike apatite on their surfaces in the body environment to bond them to living bone. Novel calcium phosphate -polylactide composites were prepared and their bioactivity was evaluated by examining a...
S. B. Cho, M. Kikuchi, J. Tanaka, R. Azumi, M. Matsumoto
Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium   1 240   Dec 1996
The Langmuir-Blodgett (LB) method has been widely studied as one of the most versatile techniques for fabricating organic thin films with well controlled composition, structure, and thickness. An experiment was conducted to determine the apatite f...
Jiao Sun, Miao Xue, Masanori Kikuchi, Masaru Akao, Hideki Aoki
Biomedical Materials and Engineering   4 503-512   Dec 1994
Strontium-hydroxyapatite microcrystals (Sr-HAp sol) were produced by a wet method at room temperature with ultrasonic irradiation and were applied to MC3T3-E1, ROS, and L cells for periods of 2, 4, and 6 days in vitro. The effect on cell growth, t...
Yoshihisa Koyama, Kazuo Takakuda, Hiroo Miyairi, Masanori Kikuchi, Junzo, Development of Bioabsorbable Membrane for Guided Bone and tissue Regeneration
Conference Proceedings,11 the Annual veterinary dental, 161-162, 1997   
Yoshihisa Koyama, Kazuo Takakuda, Hiroo Miyairi, Masanori Kikuchi, Junzo Tanaka, Development of a Tricalucium-Phosphate Membrane for Guided tissue Regeneration
Conference Proceeding,11 th Annual veterinary dental, 163-164, 1997   
Yoshihisa Koyama, Hiroko Matsumoto, Kazuo Takakuda, Hiroo Miyairi, Peter Emily, Masanori Kikuchi, Yasushi Suetsugu, Junzo Tanaka, Midori Shishikura, Katsuyoshi Nagaoka, Toshifumi Kosaka, Shigeo Tanaka, Soichiro Ito, Kenichi Shinomiya, Kiyoshi Kawas・・・
Conference Proceedings, 13 th Annual Veterinary Dental Forum, 66-68, 1999   
Yoshihisa Koyama, Hiroko Matsumoto, Kazuo Takakuda,
Hiroo Miyairi, Peter Emily, Masanori Kikuchi,
Yasushi Suetsugu, Junzo Tanaka, Midori Shishikura,
Katsuyoshi Nagaoka, Toshifumi Kosaka, Shigeo Tanaka,
Soichiro Ito, Kenichi Shinomiya, Kiyoshi ...
Yasushi Suetsugu, Masanori Kikuchi, Kimiyasu Sato, Junzo Tanaka, Crystal Grow and Analysis of Carbonate Hydroxypatite,
Bioceramics, 11, 93-95, 1998,   
Yasushi Suetsugu, Ichiro Shimoya, Masanori Kikuchi, Junzo Tanaka, Crystal Growth of Carbonate Apatite using CaCO3-Ca(OH)2Flux
Phosphorous Research Bulletin, 6, 225-228, 1996   
Y. Koyama, H. Matsumoto, K. Takakuda, H. Miyairi, M. Kikuchi, J. Tanaka, Guided Bone Regeneration with Bioabsorbabe Organic/Inorganic Composite Membrane
Proc of International, Workshop on Bio-integrated Materials & Tissue Engineering, 70-71, 2000   
Tohru Takagi, Ryuichi Fujisawa, Masaru Akao, Masanori Kikuchi, Noriyuki Nagai, Satoshi Sasaki Effects of Bovine Amelogenin and Enamelin on in Vitro Mineralization in Gel
J.Hard Tissue Biology. 5, 15-22, 1996   
Sung-Baek Cho, Masanori Kikuchi, Yasuchi Suetsugu, Junzo Tanaka Novel Calcium Phosphate/Polylactide Composites: Its in Vitro Evaluation
Key Engineering Materials. 132-136, 802-805, 1997   
Sung-Baek Cho, Kimiyasu Sato, Masanori Kikuchi, Yasushi Suetsugu, Zeta Potential of Various Bioactive Ceramics and Organic/Inorganic Composites
Proceeding of The 14 th Japan-Kore a Seminar on, 123-126, 1997   
Soichiro Itoh, Masanori Kikuchi, Kazuo Takakuda, Yoshihisa Koyama, Hiroko N. Matsumoto, Shizuko Ichinose, Junzo Tanaka, Toshiyuki Kawauchi and Kenichi Shinomiya The Biocompatibility and Osteoconductivie Activity of a Novel Biomaterial, Hydroxyapatit・・・
Journal of Biomedical, Materials Research, in print   
Soichiro Itoh, Masanori Kikuchi, Kazuo Takakuda,
Yoshihisa Koyama, Hiroko N. Matsumoto, Shizuko Ichinose,
Junzo Tanaka, Toshiyuki Kawauchi and Kenichi Shinomiya
The Biocompatibility and Osteoconductivie Activity of a
Novel Biomaterial, Hydroxya...
Pao-Li Wang, Shinya Shirasu, Mitsuki Shinohara, Michihatu Daito, Masanori Kikuchi, Yasushi Suetsugu, Junzo Tanaka, Kiyoshi Ohura The Singnal Transduction Pathway from Prophyromonas Gingivalis LPS-Stimulated Gingivalis Fibroblasts to Osteoclast Activ・・・
Medical Sci. Res. 27, 311-313, 1999   
Pao-Li Wang, Shinya Shirasu, Mitsuki Shinohara,
Michihatu Daito, Masanori Kikuchi,
Yasushi Suetsugu, Junzo Tanaka, Kiyoshi Ohura
The Singnal Transduction Pathway from Prophyromonas
Gingivalis LPS-Stimulated Gingivalis Fibroblasts to
Osteoclast ...
P. Zhou, M. Hosonuma, M. Kikuchi, J. Tanaka, S. Nakamura, M. Ohgaki and M. Akao, Thermal Decomposition Methods for HA and CaTiO3 Coating Titanium,
Bioceramics, 9, 349-352, 1996   
Naofumi Murata, Akiyoshi Osaka, Kenji Ito, Masanori Kikuchi, Yasushi Suetsugu, Junzo.Tanaka, Organic/Inorganic Interaction Between Hydroxyapatite and Derivatives of Poly(Etylene Glycol)
Transactions of the Materials Research Society of Japan, 24(4), 549-552, 1999   
Masanori Kikuchi, Yoshihisa Koyama, Kazuo Takakuda, Hiroo Miyairi, Junzo Tanaka, In vitro test and Aplication for Guided Bone Regeneration of bete-tricalcium Phosphate /Poly- (Iactide-Glycolic Acid-epsilon-Caprolactone)Composite
Key-Engineering(Biomaterials 13)195,   
Masanori Kikuchi, Yasushi Suetsugu, Junzo Tanaka, Masaru Akao, Preparation of Calcium Phosphate-CPLA Composite
Bioceramics, 9, 395-398, 1996   
Masanori Kikuchi, Yasushi .Suetsugu, Junzo Tanaka, Soichiro Ito, Shizuko Ichinose, Kenichi Shinomiya, Yousuke Hiraoka, Yoshinobu Mandai, Shinichi Nakatani, The Biomimetic Synthesis and Biocompatibility of Self-Organized Hydroxyapatite/Collagen Compo・・・
Bioceramics, 12, 393-396, 1999   
Masanori Kikuchi, Yasushi .Suetsugu, Junzo Tanaka,
Soichiro Ito, Shizuko Ichinose,
Kenichi Shinomiya, Yousuke Hiraoka, Yoshinobu Mandai,
Shinichi Nakatani,
The Biomimetic Synthesis and Biocompatibility of
Self-Organized Hydroxyapatite/Collagen ...
Masanori Kikuchi, Sung-Baek Cho, Yasushi Suetsugu, Junzo Tanaka, In vitro and in vivo tests of newly developed TCP/CPLA composites,
Bioceramics, 10, 407-410, 1997   
Masanori Kikuchi, Sung-Baek Cho, Yasushi Suetsugu, Junzo Tanaka, Yoshihisa Koyama, Takayuki Kobayashi, Kazuo Takakuda, Masaru Akao, Toshiki Shikata, Yutaka Tashiro, Mechanical and Osteoconductive Properties of TCP/CPLA Composites,
Proceeding of The 14 th Japan-Kore a Seminar on Ceramics, 268-271, 1997   
Masanori Kikuchi, Soichiro Itoh, Shizuko Ichinose, Kenichi Shinomiya and Junzo Takada Self-Organization Mechanism in Bone-like Hydroxyapatite / Collagen Nanocomposite Synthesized in vitro and lts Biological Reaction in vivo
Biomaterials, in print   
Masanori Kikuchi, Seisuke Kano, Atsushi Yamazaki, Ryohei Otsuka, Masataka Ohgaki, Satoshi Nakamura, Masaru Akao, Hideki Aoki, Hydrothermal Synthesis of Sr-Substituted Hydroxyapatite,
Phosphorous Research Bulletin, 1, 483-488, 1991   
Masanori Kikuchi, Kimiyasu Sato, Yasushi Suetsugu, Junzo Tanaka, Yoshihisa Koyama, Kazuo Takakuda, Changes in Mechanical Properties and GBR Application of TCP/CPLA Composite
Bioceramics, 11, 153-156, 1998   
Masanori Kikuchi, Junzo Tanaka, Soichiro Ito, Shizuko Ichinose, Yoshihisa Koyama, Kazuo Takakuda, Katsuyoshi Nagaoka, Shigeo Tanaka, Preparation of Hydroxyapatite / Collagen Composites Using Biomimetic Process and Their Biocompatibility
Material Research Society Symposium Proceeding, 599, 51-53, 2000   
M. Kikuchi, J. Tanaka, S. Itoh, Preparation using Self-Organization Process and Bone Tissue Reaction of Hydroxyapatite/Collagen
Proc of International, Workshop on Bio-integrated, 68, 2000   
M. Kikuchi, A. Yamazaki, L. Ning, S. Okayama, M. Akao and H. Aoki, Biocompatibility of Strontium Hydroxyapatite,
Biomedical Materials Research in Far East(II), 129-130, 1996   
Kimiyasu Sato, Yasushi Suetsugu, Masanori Kikuchi, Yuri Kumagai, Junzo Tanaka, Electrostatic and Structural Analysis of Phosphate/Organic Materials Interfaces,
Bioceramics, 11, 485-488, 1998   
K. Takakuda, Y. Koyama, H. Matsumoto, H. Miyairi, S. Itoh, K. Shinomiya, M. Kikuchi, J. Tanaka, K. Nagaoka, T. Kosaka, S. Tanaka, Bone Reconstruction with Hydroxyapatite/Collagen
Proc of International, Workshop on Bio-integrated Materials & Tissue Engineering, 72-73, 2000   

Research Grants & Projects

 
Biological Tissue Inductive Bioabsorbable Organic/Inorganic Composite Materials
Synthesis and evaluation of hydroxyapatite/collagen self-organized bone-like nanocomposite