金子清俊 (Kiyotoshi Kaneko) - マイポータル

基本情報

所属: 東京医科大学医学部医学科神経生理学講座主任教授,教授

学位: 医学博士
博士 (医学)(新潟大学)

J-GLOBAL ID: 200901040906485966
researchmap会員ID: 5000000739

外部リンク: http://www.asahi-net.or.jp/~zd8k-knk/

研究キーワード

研究分野

経歴

もっとみる

学歴

- 1983年

新潟大学医学部, 医学部
- 1983年

新潟大学

MISC

14-3-3zeta is indispensable for aggregate formation of polyglutamine-expanded huntingtin protein

Kazuya Omi, Naomi S. Hachiya, Mayumi Tanaka, Katsushi Tokunaga, Kiyotoshi Kaneko

NEUROSCIENCE LETTERS 431(1) 45-50 2008年1月
Screening of DNA Aptamer Against Mouse Prion Protein by Competitive Selection

Daisuke Ogasawara, Hijiri Hasegawa, Kiyotoshi Kaneko, Koji Sode, Kazunori Ikebukuro

PRION 1(4) 248-254 2007年10月
The possible role of protein X, a putative auxiliary factor in pathological prion replication, in regulating a physiological endoproteolytic cleavage of cellular prion protein

Naomi S. Hachiya, Midori Imagawa, Kiyotoshi Kaneko

MEDICAL HYPOTHESES 68(3) 670-673 2007年
Intracerebroventricular delivery of dominant negative prion protein in a mouse model of iatrogenic Creutzfeldt-Jakob disease after dura graft transplantation

K Furuya, N Kawahara, Y Yamakawa, H Kishida, NS Hachiya, M Nishijima, T Kirino, K Kaneko

NEUROSCIENCE LETTERS 402(3) 222-226 2006年7月
Three-repeat Tau 69 is a major tau isoform in laser-microdissected Pick bodies

T Ohkubo, Y Sakasegawa, H Toda, H Kishida, K Arima, M Yamada, H Takahashi, H Mizusawa, NS Hachiya, K Kaneko

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 13(1) 1-5 2006年3月
siRNA-mediated inhibition of endogenous Huntington disease gene expression induces an aberrant configuration of the ER network in vitro

K Omi, NS Hachiya, K Tokunaga, K Kaneko

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 338(2) 1229-1235 2005年12月
More than a 100-fold increase in immunoblot signals of laser-microdissected inclusion bodies with an excessive aggregation property by oligomeric actin interacting protein 2/D-lactate dehydrogenase protein 2

NS Hachiya, T Ohkubo, Y Kozuka, M Yamazaki, O Mori, H Mizusawa, Y Sakasegawa, K Kaneko

ANALYTICAL BIOCHEMISTRY 347(1) 106-111 2005年12月
More than a 100-fold increase in immunoblot signals of laser-microdissected inclusion bodies with an excessive aggregation property by oligomeric actin interacting protein 2/D-lactate dehydrogenase protein 2

NS Hachiya, T Ohkubo, Y Kozuka, M Yamazaki, O Mori, H Mizusawa, Y Sakasegawa, K Kaneko

ANALYTICAL BIOCHEMISTRY 347(1) 106-111 2005年12月
Prion protein with Y145STOP mutation induces mitochondria-mediated apoptosis and PrP-containing deposits in vitro

NS Hachiya, K Watanabe, MY Kawabata, A Jozuka, Y Kozuka, Y Sakasegawa, K Kaneko

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 327(3) 894-899 2005年2月
Oligomeric Aip2p/Dld2p modifies the protein conformation of both properly folded and misfolded substrates in vitro

NS Hachiya, Y Sakasegawa, H Sasaki, A Jozuka, S Tsukita, K Kaneko

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 323(1) 339-344 2004年10月
Oligomeric Aip2p/Dld2p forms a novel grapple-like structure and has an ATP-dependent F-actin conformation modifying activity in vitro

NS Hachiya, Y Sakasegawa, H Sasaki, A Jozuka, S Tsukita, K Kaneko

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 320(4) 1271-1276 2004年8月
Interaction of D-lactate dehydrogenase protein 2 (Dld2p) with F-actin: Implication for an alternative function of Dld2p

NS Hachiya, Y Sakasegawa, A Jozuka, S Tsukita, K Kaneko

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 319(1) 78-82 2004年6月
Anterograde and retrograde intracellular trafficking of fluorescent cellular prion protein

NS Hachiya, K Watanabe, M Yamada, Y Sakasegawa, K Kaneko

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 315(4) 802-807 2004年3月
Microtubules-associated intracellular localization of the NH2-terminal cellular prion protein fragment

NS Hachiya, K Watanabe, Y Sakasegawa, K Kaneko

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 313(3) 818-823 2004年1月
Absence of association between codon 129/219 polymorphisms of the prion protein gene and Alzheimer's disease in Japan

T Ohkubo, Y Sakasegawa, T Asada, T Kinoshita, Y Gore, H Kimura, H Mizusawa, NS Hachiya, K Kaneko

ANNALS OF NEUROLOGY 54(4) 553-554 2003年10月
Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene

C Korth, K Kaneko, D Groth, N Heye, G Telling, J Mastrianni, P Parchi, P Gambetti, R Will, J Ironside …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(8) 4784-4789 2003年4月
Dominant-negative inhibition of prion replication in transgenic mice

Perrier, V, K Kaneko, J Safar, J Vergara, P Tremblay, SJ DeArmond, FE Cohen, SB Prusiner, AC Wallace

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(20) 13079-13084 2002年10月
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

D Peretz, RA Williamson, K Kaneko, J Vergara, E Leclerc, G Schmitt-Ulms, IR Mehlhorn, G Legname, MR Wormald, PM Rudd …

NATURE 412(6848) 739-743 2001年8月
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

Nature 412 : 739-743 2001年

金子清俊

基本情報

研究キーワード

研究分野

経歴

学歴

MISC

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

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