Osamu SHIROTA

J-GLOBAL         Last updated: Nov 10, 2018 at 11:04
 
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Name
Osamu SHIROTA
Affiliation
Tokushima Bunri University
Section
Kagawa School of Pharmaceutical Sciences
Job title
Professor
Degree
Ph.D.(Tokyo University of Pharmacy and Life Science)

Academic & Professional Experience

 
Apr 2013
 - 
Today
Professor, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University
 
Apr 2007
 - 
Mar 2013
Associate Professor, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University
 
Apr 2004
 - 
Mar 2007
Associate Professor, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University
 
Apr 2001
 - 
Mar 2004
Senior Research Scientist, Division of Pharmacognosy, National Institute of Health Sciences
 
Apr 1997
 - 
Mar 2001
Research Scientist, Division of Pharmacognosy, National Institute of Health Sciences
 
Mar 1998
 - 
Mar 2000
Visiting Scientist, Department of Chemistry, Columbia University
 
Sep 1994
 - 
Mar 1997
Postdoctoral research fellow, Science and Technology Agency
 
Apr 1994
 - 
Aug 1994
National Institute of Health Sciences
 
Apr 1990
 - 
Mar 1991
Researcher, Institute of Molecular Genetics, Tsumura Co.
 

Education

 
Apr 1991
 - 
Mar 1994
Graduate School of Pharmaceutical Sciences, Tokyo College of Pharmacy
 
Apr 1988
 - 
Mar 1990
Doctoral Course, Graduate School of Pharmaceutical Sciences, Tokyo College of Pharmacy
 
Apr 1984
 - 
Mar 1988
Faculty of Pharmaceutical Science, Tokyo College of Pharmacy
 

Published Papers

 
Nugroho AE, Inoue D, Wong CP, Hirasawa Y, Kaneda T, Shirota O, Hadi AHA, Morita H
Journal of natural medicines      Feb 2018   [Refereed]
Tokumura T, Kurita T, Yoshida N, Mori-Yasumoto K, Shirota O
Journal of pharmaceutical analysis   7(5) 297-302   Oct 2017   [Refereed]
Apowalsogynes A and B, Two Highly Oxidized 3,4-Seco- Apotirucallane Triterpenoids from Walsura chrysogyne.
Nugroho AE, Okuda M, Yamamoto Y, Chin-Piow W, Hirasawa Y, Kaneda T, Shirota O, Hadi AHA, Morita H
Natural Product Communications   12(8) 1189-1192   2017   [Refereed]
Paudel MK, Shirota O, Sakamoto S, Morimoto S, Tanaka H
Journal of Immunoassay and Immunochemistry   38(4) 438-448   2017   [Refereed]
Daphnane Diterpenoids from Daphne altaica.
Nugroho AE, Chin-Piow W, Hirasawa Y, Janar J, Kaneda T, Shirota O, Morita H
Natural Product Communications   11(8) 1073-1075   2016   [Refereed]
Komoto N, Nakane T, Matsumoto S, Hashimoto S, Shirota O, Sekita S, Kuroyanagi M
Journal of Natural Medicines   69(4) 479-486   Oct 2015   [Refereed]
A new benzylisoquinoline alkaloid from Leontice altaica
Jenis J, Nugroho Alfarius E, Hashimoto A, Deguchi J, Hirasawa Y, Wong Chin P, Kaneda T, Shirota O, Morita H
Natural Product Communications   10(2) 291-292   Feb 2015   [Refereed]
Haseo A, Nugroho AE, Hirasawa Y, Kaneda T, Shirota O, Rahman A, Kusumawati I, Zaini NC, Morita H
Heterocycles   90(1) 601-606   2015   [Refereed]
Flavonoid glucuronides isolated from spinach inhibit IgE-mediated degranulation in basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice.
Morishita Y, Saito E, Takemura E, Fujikawa R, Yamamoto R, Kuroyanagi M, Shirota O, Muto N
Integrative Molecular Medicine   2(2) 99-205   2015   [Refereed]
Diterpenoids from Fagonia mollis
Sallam A, Nugroho AE, Hirasawa Y, Chin-Piow W, Kaneda T, Shirota O, Gedara SR, Morita H
Natural Product Communications   9(9) 1243-1244   Sep 2014   [Refereed]
Morita H, Nugroho AE, Nagakura Y, Hirasawa Y, Yoshida H, Kaneda T, Shirota O, Ismail IS
Bioorganic & Medicinal Chemistry Letters   24(11) 2437-2439   Jun 2014   [Refereed]
Kiren Y, Nugroho AE, Hirasawa Y, Shirota O, Bekenova M, Narbekovich NO, Shapilova M, Maeno H, Morita H
Journal of Natural Medicines   68(1) 199-205   Jan 2014   [Refereed]
Mori R, Nugroho AE, Hirasawa Y, Wong CP, Kaneda T, Shirota O, Hadi AH, Morita H
Journal of natural medicines   68(1) 186-191   Jan 2014   [Refereed]
Deguchi J, Sasaki T, Hirasawa Y, Kaneda T, Kusumawati I, Shirota O, Morita H
Tetrahedron Letters   55(7) 1362-1365   2014   [Refereed]
Kuroyanagi M, Shirota O, Sekita S
Chemical & Pharmaceutical Bulletin   62(7) 725-728   2014   [Refereed]
Paudel MK, Shirota O, Sasaki-Tabata K, Tanaka H, Sekita S, Morimoto S
Journal of Natural Products   76(9) 1654-1660   Sep 2013   [Refereed]
Yamasaki F, Machida S, Nakata A, Nugroho AE, Hirasawa Y, Kaneda T, Shirota O, Hagane N, Sugizaki T, Morita H
Journal of Natural Medicines   67(1) 212-216   Jan 2013   [Refereed]
Hirasawa, Yusuke Arai, Hiroko Rahman, Abdul Kusumawati, Idha Zaini, Noor Cholies Shirota, Osamu Morita, Hiroshi
Tetrahedron   69(51) 10869-10875   2013   [Refereed]
Nugroho, Alfarius E. Okuda, Maho Yamamoto, Yukari Hirasawa, Yusuke Wong, Chin-Piow Kaneda, Toshio Shirota, Osamu Hadi, A. Hamid A. Morita, Hiroshi
Tetrahedron   69(20) 4139-4145   2013   [Refereed]
Wong CP, Shimada M, Nugroho AE, Hirasawa Y, Kaneda T, Hadi AH, Osamu S, Morita H
Journal of Natural Medicines   66(3) 566-570   Jul 2012   [Refereed]
Nugroho AE, Hirasawa Y, Piow WC, Kaneda T, Hadi AH, Shirota O, Ekasari W, Widyawaruyanti A, Morita H
Journal of Natural Medicines   66(2) 350-353   Apr 2012   [Refereed]
Transannular cyclization of (4S,5S)-germacrone-4,5-epoxide into guaiane and secoguaiane-type sesquiterpenes.
Kuroyanagi M, Shirota O, Sekita S, Nakane T
Natural Product Communications   7(4) 441-446   Apr 2012   [Refereed]
Deguchi J, Hirahara T, Hirasawa Y, Ekasari W, Widyawaruyanti A, Shirota O, Shiro M, Morita H
Chemical & Pharmaceutical Bulletin   60(2) 219-222   2012   [Refereed]
He F, Nugroho AE, Wong CP, Hirasawa Y, Shirota O, Morita H, Aisa HA
Chemical & Pharmaceutical Bulletin   60(2) 213-218   2012   [Refereed]
Deguchi, Jun Shoji, Tomokazu Hirasawa, Yusuke Rahman, Abdul Shirota, Osamu Morita, Hiroshi
Heterocycles   86(2) 1603-1610   2012   [Refereed]
Janar J, Nugroho AE, Wong CP, Hirasawa Y, Kaneda T, Shirota O, Morita H
Chemical & Pharmaceutical Bulletin   60(1) 154-159   2012   [Refereed]
Kuroyanagi M, Murata M, Nakane T, Shirota O, Sekita S, Fuchino H, Shinwari ZK
Chemical & Pharmaceutical Bulletin   60(7) 892-897   2012   [Refereed]
Deguchi J, Hirahara T, Oshimi S, Hirasawa Y, Ekasari W, Shirota O, Honda T, Morita H
Organic Letters   13(16) 4344-4347   Aug 2011   [Refereed]
Najmuldeen IA, Hadi AH, Awang K, Mohamad K, Ketuly KA, Mukhtar MR, Chong SL, Chan G, Nafiah MA, Weng NS, Shirota O, Hosoya T, Nugroho AE, Morita H
Journal of Natural Products   74(5) 1313-1317   May 2011   [Refereed]
Tanaka H, Atsumi I, Shirota O, Sekita S, Sakai E, Sato M, Murata J, Murata H, Darnaedi D, Chen IS
Chemistry & Biodiversity   8(3) 476-482   Mar 2011   [Refereed]
Shirota O, Oribello JM, Sekita S, Satake M
Journal of Natural products   74(3) 470-476   Mar 2011   [Refereed]
Qureshi AK, Mukhtar MR, Hirasawa Y, Hosoya T, Nugroho AE, Morita H, Shirota O, Mohamad K, Hadi AH, Litaudon M, Awang K
Chemical & Pharmaceutical Bulletin   59(2) 291-293   Feb 2011   [Refereed]
Taha H, Hadi AH, Nordin N, Najmuldeen IA, Mohamad K, Shirota O, Nugroho AE, Piow WC, Kaneda T, Morita H
Chemical & Pharmaceutical Bulletin   59(7) 896-897   2011   [Refereed]
Deguchi J, Shoji T, Nugroho AE, Hirasawa Y, Hosoya T, Shirota O, Awang K, Hadi AH, Morita H
Journal of Natural Products   73(10) 1727-1729   Sep 2010   [Refereed]
Kawauchi M, Arima T, Shirota O, Sekita S, Nakane T, Takase Y, Kuroyanagi M
Chemical & Pharmaceutical Bulletin   58(7) 934-938   Jul 2010   [Refereed]
Komoto N, Ichikawa M, Ohta S, Nakano D, Nishihama T, Ushijima M, Kodera Y, Hayama M, Shirota O, Sekita S, Kuroyanagi M
Journal of Natural Medicines   64(3) 321-329   Jul 2010   [Refereed]
Ishida Y, Shirota O, Sekita S, Someya K, Tokita F, Nakane T, Kuroyanagi M
Chemical & Pharmaceutical Bulletin   58(3) 336-343   Mar 2010   [Refereed]
Teh, Chin-Hoe Morita, Hiroshi Shirota, Osamu Chan, Kit-Lam
Food Chemistry   120(3) 794-798   2010   [Refereed]
Liu, Yongqiang Nugroho, Alfarius E. Hirasawa, Yusuke Nakata, Asami Kaneda, Toshio Uchiyama, Nahoko Goda, Yukihiro Shirota, Osamu Morita, Hiroshi Aisa, Haji Akber
Tetrahedron Letters   51(50) 6584-65847   2010   [Refereed]
Oshimi S, Deguchi J, Hirasawa Y, Ekasari W, Widyawaruyanti A, Wahyuni TS, Zaini NC, Shirota O, Morita H
Journal of Natural Products   72(10) 1899-1901   Oct 2009   [Refereed]
Matsushima Y, Shirota O, Kikura-Hanajiri R, Goda Y, Eguchi F
Bioscience, Biotechnology, and Biochemistry   73(8) 1866-1868   Aug 2009   [Refereed]
Suzuki A, Shirota O, Mori K, Sekita S, Fuchino H, Takano A, Kuroyanagi M
Chemical & Pharmaceutical Bulletin   57(3) 245-251   Mar 2009   [Refereed]
Ichikawa M, Ohta S, Komoto N, Ushijima M, Kodera Y, Hayama M, Shirota O, Sekita S, Kuroyanagi M
Journal of Natural Medicines   63(1) 52-57   Jan 2009   [Refereed]
Ichikawa M, Ohta S, Komoto N, Ushijima M, Kodera Y, Hayama M, Shirota O, Sekita S, Kuroyanagi M
Journal of Natural Medicines   62(4) 423-429   Oct 2008   [Refereed]
Gao HY, Wu LJ, Nakane T, Shirota O, Kuroyanagi M
Chemical & Pharmaceutical Bulletin   56(9) 1352-1354   Sep 2008   [Refereed]
Shirota O, Nagamatsu K, Sekita S, Komoto N, Kuroyanagi M, Ichikawa M, Ohta S, Ushijima M
Phytochemical analysis : PCA   19 403-410   Sep 2008   [Refereed]
Gao HY, Wu LJ, Muto N, Fuchino H, Nakane T, Shirota O, Sano T, Kuroyanagi M
Chemical & Pharmaceutical Bulletin   56(7) 1030-1034   Jul 2008   [Refereed]
Gao HY, Wu LJ, Nakane T, Shirota O, Kuroyanagi M
Chemical & Pharmaceutical Bulletin   56(4) 554-558   Apr 2008   [Refereed]
Ushijima M, Komoto N, Sugizono Y, Mizuno I, Sumihiro M, Ichikawa M, Hayama M, Kawahara N, Nakane T, Shirota O, Sekita S, Kuroyanagi M
Chemical & Pharmaceutical Bulletin   56(3) 308-314   Mar 2008   [Refereed]
Morita H, Hirasawa Y, Muto A, Yoshida T, Sekita S, Shirota O
Bioorganic & Medicinal Chemistry Letters   18(3) 1050-1052   Feb 2008   [Refereed]
Kuroyanagi M, Ishii H, Kawahara N, Sugimoto H, Yamada H, Okihara K, Shirota O
Journal of Natural Medicines   62(1) 107-111   Jan 2008   [Refereed]
Shirota, O., Nagamatsu, K., Sekita, S., Komoto, N., Kuroyanagi, M., Ichikawa, M., Ohta, S., Ushijima, M.
Phytochem. Anal.   19(5) 403-410   2008   [Refereed]
Morita, H., Hirasawa, Y., Muto, A., Yoshida, T., Sekita, S., Shirota, O.
Bioorg. Med. Chem. Lett.   18(3) 1050-1052   2008   [Refereed]
Shirota O, Nagamatsu K, Sekita S
Journal of Natural Products   69(12) 1782-1786   Dec 2006   [Refereed]
Saito K, Toyo'oka T, Kato M, Fukushima T, Shirota O, Goda Y
Talanta   66(3) 562-568   Apr 2005   [Refereed]
Shirota O, Sekita S, Satake M, Morita H, Takeya K, Itokawa H
Chemistry & Biodiversity   1 1296-1307   Sep 2004   [Refereed]
Shirota O, Sekita S, Satake M, Morita H, Takeya K, Itokawa H
Chemical & Pharmaceutical Bulletin   52(9) 1148-1150   Sep 2004   [Refereed]
Shirota O, Sekita S, Satake M, Morita H, Takeya K, Itokawa H
Chemical & Pharmaceutical Bulletin   52(6) 739-746   Jun 2004   [Refereed]
Helv. Chim. Acta   87(6), 1539-1544    2004
Shirota O, Pathak V, Sekita S, Satake M, Nagashima Y, Hirayama Y, Hakamata Y, Hayashi T
Journal of Natural Products   66(8) 1128-1131   Aug 2003   [Refereed]
Shirota O, Hakamata W, Goda Y
Journal of Natural Products   66(6) 885-887   Jun 2003   [Refereed]
Can. J. Chem   79(11), 1786-1791    2001
Random amplified polymorphic DNA and restriction fragment length polymorphism analyses of Cannabis sativa
Natural Medicines   52(2), 160-166    1998
Yun, Young Sook; Shimizu, Kazuhiro; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Shirota, Osamu
Phytochemistry   47(1) 143-144   1998   [Refereed]
Shirota, Osamu; Sekita, Setsuko; Hirayama, Yutaka; Hakamata, Yusuke; Hayashi, Tatsuo; Yanagawa, Takuma; Satake, Motoyoshi
Phytochemistry   47(7) 1381-1385   1998   [Refereed]
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Chemical & Pharmaceutical Bulletin   46(1) 102-106   1998   [Refereed]
Isolation of antitumor substance, dulcitol, from Maytenus ebenifolia
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Natural Medicines (Tokyo)   52(2) 184-186   1998   [Refereed]
Structural elucidation of trichotetronines: polyketides possessing a bicyclo[2.2.2] octane skeleton with a tetronic acid moiety isolated from Trichoderma sp
J. Chem. Soc. Perkin Trans.1.   2961-2964    1997
Shirota, Osamu; Takizawa, Kenji; Sekita, Setsuko; Satake, Motoyoshi; Hirayama, Yutaka; Hakamada, Yusuke; Hayashi, Tatsuo; Yanagawa, Takuma
Journal of Natural Products   60(10) 997-1002   1997   [Refereed]
Shirota, Osamu; Sekita, Setsuko; Satake, Motoyoshi; Ni, Yan; Weiyi, Hua
Phytochemistry   44(4) 695-698   1997   [Refereed]
Cytotoxic triterpene from Aster tataricus
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Natural Medicines (Tokyo)   51(2) 170-172   1997   [Refereed]
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Journal of Natural Products   60(2) 111-115   1997   [Refereed]
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Journal of Natural Products   60(11) 1100-1104   1997   [Refereed]
Lignans from a cactus, Opuntia soehrensii
Shirota, Osamu; Kumakura, Morihiko; Sekita, Setsuko; Satake, Motoyoshi
Natural Medicines (Tokyo)   51(3) 281-281   1997   [Refereed]
Pathak, Vibha; Shirota, Osamu; Sekita, Setsuko; Hirayama, Yutaka; Hakamata, Yusuke; Hayashi, Tatsuo; Yanagawa, Takuma; Satake, Motoyoshi
Phytochemistry   46(7) 1219-1223   1997   [Refereed]
Morita, Hiroshi; Yun, Young Sook; Takeya, Koichi; Itokawa, Hideji; Yamada, Kenji; Shirota, Osamu
Bioorganic & Medicinal Chemistry Letters   7(8) 1095-1096   1997   [Refereed]
Morita, Hiroshi; Yun, Young Sook; Takeya, Koichi; Itokawa, Hideji; Shirota, Osamu
Bioorganic & Medicinal Chemistry   5(3) 631-636   1997   [Refereed]
Morita, Hiroshi; Gonda, Akira; Takeya, Koichi; Itokawa, Hideji; Shirota, Osamu
Chemical & Pharmaceutical Bulletin   45(1) 161-164   1997   [Refereed]
Morita, Hiroshi; Gonda, Akira; Takeya, Koichi; Itokawa, Hideji; Hirano, Toshihiko; Oka, Kitaro; Shirota, Osamu
Tetrahedron   53(22) 7469-7478   1997   [Refereed]
Shirota, Osamu; Tamemura, Toshihiko; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji
Journal of Natural Products   59(11) 1072-1075   1996   [Refereed]
Chemical constituents of Chinese folk medicine "San Leng", Sparganium stoloniferum
Shirota, Osamu; Sekita, Setsuko; Satake, Motoyoshi; Ni, Yan; Weiyi, Hua
Journal of Natural Products   59(3) 242-245   1996   [Refereed]
Morita, Hiroshi; Yun, Young Sook; Takeya, Koichi; Itokawa, Hideji; Shirota, Osamu
Phytochemistry   42(2) 439-441   1996   [Refereed]
Morita, Hiroshi; Yoshida, Natsuko; Takeya, Koichi; Itokawa, Hideji; Shirota, Osamu
Tetrahedron   52(8) 2795-2802   1996   [Refereed]
Kamano, Yoshiaki; Zhang, Hui-ping; Morita, Hiroshi; Itokawa, Hideji; Shirota, Osamu; Pettit, George R.; Herald, Delbert L.; Herald, Cherry L.
Tetrahedron   52(7) 2369-2376   1996   [Refereed]
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Tetrahedron   51(4) 1107-1120   1995   [Refereed]
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Chemistry Letters   (2) 101-102   1995   [Refereed]
Sesquiterpene pyridine alkaloids from Maytenus chuchuhuasca
Shirota, Osamu; Otsuka, Akiko; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji
Heterocycles   38(10) 2219-2229   1994   [Refereed]
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Journal of Natural Products   57(12) 1675-1681   1994   [Refereed]
Sesquiterpene pyridine alkaloids from Maytenus ilicifolia
Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Itokawa, Hideji; Iitaka, Yoichi
Heterocycles   38(2) 383-389   1994   [Refereed]
Itokawa, Hideji; Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Iitaka, Yoichi
Journal of Natural Products   57(4) 460-470   1994   [Refereed]
Morita, Hiroshi; Nagashima, Shinji; Shirota, Osamu; Takeya, Koichi; Itokawa, Hideji
Chemistry Letters   (11) 1877-1880   1993   [Refereed]
Isolation, structural elucidation and conformational analysis of sesquiterpene pyridine alkaloids from Maytenus ebenifolia Reiss. X-ray molecular structure of ebenifoline W-I
Itokawa, Hideji; Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Iitaka, Yoichi
Journal of the Chemical Society, Perkin Transactions 1   (11) 1247-1254   1993   [Refereed]
Itokawa, Hideji; Shirota, Osamu; Ichitsuka, Kenichiro; Morita, Hiroshi; Takeya, Koichi
Journal of Natural Products   56(9) 1479-1485   1993   [Refereed]
Sesquiterpene pyridine alkaloids from Maytenus ebenifolia
Itokawa, Hideji; Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Tomioka, Nobuo; Itai, Akiko
Heterocycles   34(5) 885-889   1992   [Refereed]
Itokawa, Hideji; Shirota, Osamu; Ikuta, Hiroshi; Morita, Hiroshi; Takeya, Koichi; Iitaka, Yoichi
Phytochemistry   30(11) 3713-3716   1991   [Refereed]
Itokawa, Hideji; Ichihara, Yoshitatsu; Mochizuki, Miwako; Enomori, Tamami; Morita, Hiroshi; Shirota, Osamu; Inamatsu, Mutsumi; Takeya, Koichi
Chemical & Pharmaceutical Bulletin   39(4) 1041-1042   1991   [Refereed]
Itokawa, Hideji; Shirota, Osamu; Morita, Hiroshi; Takeya, Koichi; Tomioka, Nobuo; Itai, Akiko
Tetrahedron Letters   31(47) 6881-6882   1990   [Refereed]

Misc

 
Foods & food ingredients journal of Japan   215(2) 144-153   2010

Research Grants & Projects

 
Study on the Chemical constituents of Harbal medicines