SHIBATA Takehiko

J-GLOBAL         Last updated: Nov 9, 2018 at 11:04
 
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Name
SHIBATA Takehiko
Affiliation
RIKEN(The Institute of Physical and Chemical Research)
Section
Graduate School of Science and Engineering Department of Physics
Job title
Unit Lieder
Degree
Ph. D.

Research Areas

 
 

Academic & Professional Experience

 
1974
   
 
RIKEN Research Scientist
 
1977
   
 
Yale Medical School Research Scientist
 
1986
 - 
2005
RIKEN Director
 
1989
 - 
2001
Saitama University, Visiting Professor
 
2001
   
 
Yokohama City University, Visiting Professor
 
2005
   
 
RIKEN Distinguished Senior Scientist
 
2010
   
 
RIKEN Advanced Science Inst. Unit Leader
 

Education

 
 
   
 
University of Tokyo, Graduate School of Science
 
 
   
 
University of Tokyo, School of Science
 

Published Papers

 
Nonfilament-forming RecA dimer catalyzes homologous joint formation
Shinohara, T., Arai, N., Iikura, Y., Kasagi, M., Masuda-Ozawa, T., Yamaguchi, Y., Suzuki-Nagata, K., Shibata, T. and Mikawa, T.
Nonfilament-forming RecA dimer catalyzes homologous joint formation   Online    Oct 2018   [Refereed]
Phenotypic diversification by enhanced genome restructuring after induction of multiple DNA double-strand breaks.
Muramoto, N., Oda, A., Tanaka, H., Nakamura, T., Kugou, K., Suda, K., Kobayashi, A., Yoneda, S., Ikeuchi, A., Sugimoto, H., Kondo, S., Ohto, C., Shibata, T., Mitsukawa, N. and Ohta, K.
Nature Communications   9 1995   May 2018   [Refereed]
Konomura N, Arai N, Shinohara T, Kobayashi J, Iwasaki W, Ikawa S, Kusano K, Shibata T
Nucleic acids research   45(1) 337-352   Jan 2017   [Refereed]
Ling F, Niu R, Hatakeyama H, Goto Y, Shibata T, Yoshida M
Molecular biology of the cell   27(10) 1684-1693   May 2016   [Refereed]
Shinohara T, Ikawa S, Iwasaki W, Hiraki T, Hikima T, Mikawa T, Arai N, Kamiya N, Shibata T
Nucleic acids research   43(2) 973-986   Jan 2015   [Refereed]
Kagawa W, Arai N, Ichikawa Y, Saito K, Sugiyama S, Saotome M, Shibata T, Kurumizaka H
Nucleic acids research   42(2) 941-951   Jan 2014   [Refereed]
Shingu, Y., Kanno, Y., Tokai, T., Shibata, T. and Wakasa, K.
Plant Biotechnology   31 55-59   Jan 2014   [Refereed]
Morozumi Y, Ino R, Ikawa S, Mimida N, Shimizu T, Toki S, Ichikawa H, Shibata T, Kurumizaka H
PloS one   8(10) e75451   Oct 2013   [Refereed]
Miura T, Shibata T, Kusano K
Proceedings of the National Academy of Sciences of the United States of America   110(40) 16067-16072   Oct 2013   [Refereed]
Iwasaki W, Miya Y, Horikoshi N, Osakabe A, Taguchi H, Tachiwana H, Shibata T, Kagawa W, Kurumizaka H
FEBS open bio   3 363-369   Aug 2013   [Refereed]
Ling F, Hori A, Yoshitani A, Niu R, Yoshida M, Shibata T
Nucleic acids research   41(11) 5799-5816   Jun 2013   [Refereed]
Shingu Y, Tokai T, Agawa Y, Toyota K, Ahamed S, Kawagishi-Kobayashi M, Komatsu A, Mikawa T, Yamamoto MT, Wakasa K, Shibata T, Kusano K
BMC molecular biology   13 1   Jan 2012   [Refereed]
Iwasaki W, Tachiwana H, Kawaguchi K, Shibata T, Kagawa W, Kurumizaka H
Biochemistry   50(36) 7822-7832   Sep 2011   [Refereed]
Arai N, Kagawa W, Saito K, Shingu Y, Mikawa T, Kurumizaka H, Shibata T
The Journal of biological chemistry   286(20) 17607-17617   May 2011   [Refereed]
Ling F, Mikawa T, Shibata T
Genes   2(1) 169-190   Feb 2011   [Refereed]
Inoue J, Nagae T, Mishima M, Ito Y, Shibata T, Mikawa T
The Journal of biological chemistry   286(8) 6720-6732   Feb 2011   [Refereed]
Takaku M, Takahashi D, Machida S, Ueno H, Hosoya N, Ikawa S, Miyagawa K, Shibata T, Kurumizaka H
Nucleic acids research   38(21) 7579-7586   Nov 2010   [Refereed]
Takizawa Y, Qing Y, Takaku M, Ishida T, Morozumi Y, Tsujita T, Kogame T, Hirota K, Takahashi M, Shibata T, Kurumizaka H, Takeda S
Nucleic acids research   38(15) 5059-5074   Aug 2010   [Refereed]
Masuda T, Ling F, Shibata T, Mikawa T
The FEBS journal   277(6) 1440-1452   Mar 2010   [Refereed]
Shingu, Y., Mikawa, T., Onuma, M., Hirayama, T. and Shibata, T.
FEBS J.   277(10) 2360-2374   2010
Ishida T, Takizawa Y, Kainuma T, Inoue J, Mikawa T, Shibata T, Suzuki H, Tashiro S, Kurumizaka H
Nucleic acids research   37(10) 3367-3376   Jun 2009   [Refereed]
Takaku M, Machida S, Hosoya N, Nakayama S, Takizawa Y, Sakane I, Shibata T, Miyagawa K, Kurumizaka H
The Journal of biological chemistry   284(21) 14326-14336   May 2009   [Refereed]
Hikiba J, Takizawa Y, Ikawa S, Shibata T, Kurumizaka H
The FEBS journal   276(2) 457-465   Jan 2009   [Refereed]
Hori, A., Yoshida, M., Shibata, T. and Ling, F.
Nucleic Acids Res.   37(3) 749-761   2009
Ling, F., Yoshida, M. and Shibata, T.
J. Biol. Chem.   284(14) 9341-9353   2009
J. Biol. Chem.
Masuda, T., Ito, Y., Terada, T., Shibata, T. and Mikawa, T.   284(44) 30230-30239   2009
Kugou, K., Fukuda, T., Yamada, S., Ito, M., Sasanuma, H., Mori, S., Katou, Y., Itoh, T., Matsumoto, K., Shibata, T., Shirahige, K. and Ohta, K.
Mol. Biol. Cell   20(13) 3064-3076   2009
Mikawa T, Lkeda M, Shibata T
Methods in molecular biology (Clifton, N.J.)   524 305-313   2009   [Refereed]
Yamada K, Hirota K, Mizuno K, Shibata T, Ohta K
Genes & genetic systems   83(5) 361-372   Oct 2008   [Refereed]
Sakane I, Kamataki C, Takizawa Y, Nakashima M, Toki S, Ichikawa H, Ikawa S, Shibata T, Kurumizaka H
Nucleic acids research   36(13) 4266-4276   Aug 2008   [Refereed]
Hikiba J, Hirota K, Kagawa W, Ikawa S, Kinebuchi T, Sakane I, Takizawa Y, Yokoyama S, Mandon-Pépin B, Nicolas A, Shibata T, Ohta K, Kurumizaka H
Nucleic acids research   36(12) 4181-4190   Jul 2008   [Refereed]
[Structural and biochemical aspects of homologous genetic (DNA) recombination].
Kurumizaka H, Mikawa T, Hikiba J, Shibata T
Seikagaku. The Journal of Japanese Biochemical Society   80(6) 511-520   Jun 2008   [Refereed]
Lin W, Hashimoto S, Seo H, Shibata T, Ohta K
Genes to cells : devoted to molecular & cellular mechanisms   13(3) 255-268   Mar 2008   [Refereed]
Inoue, J., Honda, M., Ikawa, S., Shibata, T. and Mikawa, T.
Nucleic Acids Res.   36(1) 94-109   2008
Sasanuma, H., Hirota, K., Fukuda, T., Kakusho, N., Kugou, K., Kawasaki, Y., Shibata, T., Masai, H. and Ohta, K.
Genes Dev.,   22(3) 398-410   2008
Hirota, K., Mizuno, K. I., Shibata, T. and Ohta, K.
Mol. Biol. Cell,   19(3) 1162-1173   2008
Honda, M., Fujisawa, T., Shibata, T. and Mikawa, T.
Nucleic Acids Res.   36(15) 5013-5020   2008
Kagawa, W., Kagawa, A., Saito, K., Ikawa, S., Shibata, T., Kurumizaka, H. and Yokoyama, S.:
J. Biol. Chem.   283(35) 24264-24273   2008
Hirota, K., Miyoshi, T., Kugou, K., Hoffman, C. S., Shibata, T. and Ohta, K.
Nature   456(7218) 130-134   2008
Hirota K, Steiner WW, Shibata T, Ohta K
Eukaryotic cell   6(11) 2072-2080   Nov 2007   [Refereed]
[Rolling circle replication: a universal model for controlling mechanisms of mitochondrial DNA copy number].
Ling F, Hori A, Yoshida M, Shibata T
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   52(8) 886-892   Jul 2007   [Refereed]
Shibata, T. and Ling, F.
Mitochondrion   7(1-2) 17-23   2007
Sasanuma H, Murakami H, Fukuda T, Shibata T, Nicolas A, Ohta K
Nucleic acids research   35(4) 1119-1133   2007   [Refereed]
Kurashima-Ito K, Ikeya T, Senbongi H, Tochio H, Mikawa T, Shibata T, Ito Y
Journal of biomolecular NMR   35(1) 53-71   May 2006   [Refereed]
Honda, M., Inoue, J., Yoshimasu, M., Ito, Y., Shibata, T. and Mikawa, T.
J. Biol. Chem.   281(27) 18549-18559   2006
Seo H, Hashimoto S, Tsuchiya K, Lin W, Shibata T, Ohta K
Nature protocols   1(3) 1502-1506   2006   [Refereed]
Sarai N, Kagawa W, Kinebuchi T, Kagawa A, Tanaka K, Miyagawa K, Ikawa S, Shibata T, Kurumizaka H, Yokoyama S
Nucleic acids research   34(16) 4429-4437   2006   [Refereed]
[Mitochondrial inheritance in yeast: mtDNA recombination and homoplasmy].
Shibata T, Ling F
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   50(14 Suppl) 1822-1826   Nov 2005   [Refereed]
Seo, H., Masuoka, M., Murofushi, H., Takeda, S., Shibata, T. and Ohta, K.:
Nature Biotechnol.,   23(6) 731-735   2005
Multiplex PCR: use of heat-stable Thermus thermophilus RecA protein to minimize non-specific PCR products
Shigemori, Y., Mikawa, T., Shibata, T. and Oishi, M.
Nucleic Acids Res.   33(14) e126   2005
Arai, N., Ito, D., Inoue, T., Shibata, T. and Takahashi, H.
J. Biol. Chem.   280(37) 32218-32229   2005
Kawasaki K, Shibata T, Ito F
Bioscience, biotechnology, and biochemistry   68(12) 2557-2564   Dec 2004   [Refereed]
Takizawa Y, Kinebuchi T, Kagawa W, Yokoyama S, Shibata T, Kurumizaka H
Genes to cells : devoted to molecular & cellular mechanisms   9(9) 781-790   Sep 2004   [Refereed]
Enomoto R, Kinebuchi T, Sato M, Yagi H, Shibata T, Kurumizaka H, Yokoyama S
The Journal of biological chemistry   279(34) 35263-35272   Aug 2004   [Refereed]
Nakayama M, Kawasaki K, Matsumoto K, Shibata T
DNA repair   3(4) 369-378   Apr 2004   [Refereed]
Honda M, Rajesh S, Nietlispach D, Mikawa T, Shibata T, Ito Y
Journal of biomolecular NMR   28(2) 199-200   Feb 2004   [Refereed]
Hirota, K., Hasemi, T., Yamada, T., Mizuno, K.-i., Hoffman, C. S., Shibata, T. and Ohta, K.
Nucleic Acids Res.   32(2) 855-862   2004
Yamada, T., Mizuno, K.-i., Hirota, K., Kon, N., Wahls, W. P., Hartsuiker, E., Murofushi, H., Shibata, T. and Ohta, K.
EMBO J.   23(8) 1792-1803   2004
Kinebuchi, T., Kagawa, W., Enomoto, R., Tanaka, K., Miyagawa, K., Shibata, T., Kurumizaka, H. and Yokoyama, S.
Mol. Cell   14(3) 363-374   2004
Yokoyama H, Sarai N, Kagawa W, Enomoto R, Shibata T, Kurumizaka H, Yokoyama S
Nucleic acids research   32(8) 2556-2565   2004   [Refereed]
Hoseki J, Okamoto A, Masui R, Shibata T, Inoue Y, Yokoyama S, Kuramitsu S
Journal of molecular biology   333(3) 515-526   Oct 2003   [Refereed]
Rajesh S, Nietlispach D, Nakayama H, Takio K, Laue ED, Shibata T, Ito Y
Journal of biomolecular NMR   27(1) 81-86   Sep 2003   [Refereed]
Murakami H, Borde V, Shibata T, Lichten M, Ohta K
Nucleic acids research   31(14) 4085-4090   Jul 2003   [Refereed]
Kurumizaka H, Enomoto R, Nakada M, Eda K, Yokoyama S, Shibata T
Nucleic acids research   31(14) 4041-4050   Jul 2003   [Refereed]
Seo H, Okuhara K, Kurumizaka H, Yamada T, Shibata T, Ohta K, Akiyama T, Murofushi H
Biochemical and biophysical research communications   303(1) 8-13   Mar 2003   [Refereed]
Yoshimasu M, Aihara H, Ito Y, Rajesh S, Ishibe S, Mikawa T, Yokoyama S, Shibata T
Nucleic acids research   31(6) 1735-1743   Mar 2003   [Refereed]
Yokoyama, H., Kurumizaka, H., Ikawa, S., Yokoyama, S. and Shibata, T.
J. Biol. Chem.   278(4) 2767-2772   2003
Fission yeast Tup1-like repressors repress chromatin remodeling at the fbp1+ promoter and the ade6-M26 recombination hotspot
Hirota, K., Hoffman, C. S., Shibata, T. and Ohta, K.
Genetics   165(2) 505-515   2003
Kawasaki K, Maruyama S, Nakayama M, Matsumoto K, Shibata T
Nucleic acids research   30(17) 3682-3691   Sep 2002   [Refereed]
Ling F, Shibata T
The EMBO journal   21(17) 4730-4740   Sep 2002   [Refereed]
Mizumura H, Shibata T, Morishima N
FEBS letters   522(1-3) 177-182   Jul 2002   [Refereed]
Counteracting regulation of chromatin remodeling at a fission yeast CRE-related recombination hotspot by SAPK, cAMP-dependent kinase, and meiosis regulators1
Geneticsm   159, 1467-1478    2001
J. Biol. Chem., 276, 35201-35208 (2001)   
A nuclear mutation defective in mitochondrial recombination in yeast
EMBO J., 14, 4090-4101 (1995)   
Changes in chromatin structure at recombination initiation sites during yeast meiosis
EMBO J., 13, 5754-5763 (1994)   
An endonuclease with multiple cutting sites, Endo. SceI, initiates genetic recombination at its cutting site in yeast mitochondria
EMBO J., 11, 2707-2715 (1992)   
A maturase-like subunit of the sequence-specific endonuclease, Endo. SceI, from yeast mitochondria
J. Biol. Chem., 266, 1977-1984 (1991)   
A new class of site-specific endo-deoxyribonucleases : Endo. SceI isolated from a eukaryote, Saccharomyces cerevisiae
J. Biol. Chem., 258, 4663-4665 (1983)   
D-loops cycle : a circular reaction sequence which comprises formation and dissociation of D-loops and inactivation and reactivation of superhelical closed circular DNA promoted by recA protein of Escherichia coli
J. Biol. Chem., 257, 13981-13986 (1982)   
Site-specific endo-deoxyribonucleases in eukaryotes : endonucleases of yeasts, Saccharomyces and Pichia
J. Biochem. (Tokyo), 90, 1623-1632 (1981)   
Purified Escherichia coli recA protein catalyzes homologous pairing of superhelical DNA and single-stranded fragments
Proc. Natl. Acad. Sci USA, 76, 1638-1642 (1979)   
Host controlled modification and restriction in Bacillus subtilis
Mol. Gen. Genet., 131, 275-280 (1974)   

Research Grants & Projects

 
Genetic, biochemical and structural biological studies on the molecular mechanisms of the initiation of homologous recombination
Biochemical and structural biological studies on the regulation of partner selection and consequence of homologous recombination.
The developments of new genome technology using controlled homologous recombination