OHASHI Toya

J-GLOBAL         Last updated: Jun 20, 2019 at 16:50
 
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Name
OHASHI Toya
Affiliation
Jikei University
Section
Institute of DNA Medicine, Department of Gene Therapy
Job title
Associate Professor
Degree
Doctor of Medical Science

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
University School of Medicine
 
 
   
 
Sinai University
 
 
   
 
Children's Hospital Los Angels
 
 
   
 
Univ. Pittsburg
 
 
   
 
Univ. School of Medicine
 
 
   
 
Medicine, The Jikei University School of Medicine
 
 
   
 
Inst. DNA Medicine, The Jikei University School of
 
 
   
 
Medicine
 
1983
   
 
: Medical Staff, Department of Pediatics, The Jikei
 
1986
   
 
: Reseach fellow, Department of Human Genetics, Mt
 

Education

 
 
   
 
The Jikei University School of Medicine
 
 
 - 
1981
Faculty of Medicine, Jikei University
 

Committee Memberships

 
1995
   
 
The Japan Society of Gene Therapy  
 
1996
   
 
Japanese Society of Inherited Metabolic Disease  
 

Awards & Honors

 
Oct 2008
Poster award, 9th European Round Table on Fabry disease, Athens, Greece
 

Published Papers

 
Characteristics of Japanese patients with X-linked adrenoleukodystrophy and concerns of their families from the 1st registry system.
Sakurai K, Ohashi T, Shimozawa N1) (1Gifu Univ), Joo-hyun S 2), Okuyama T 2)(2 National Center for Child Health and Development), Ida H.
Brain Dev.   4(1) 50-56   Jan 2019   [Refereed]
Nafamostat Mesilate Enhances the Radiosensitivity and Reduces the Radiation-Induced Invasive Ability of Colorectal Cancer Cells.
Sugano H, Shirai Y, Horiuchi T, Saito N, Shimada Y, Eto K, Uwagawa T, Ohashi T, Yanaga K.
Cancers (Basel).   10(10) E386   2018   [Refereed]
P-Tau and Subunit c Mitochondrial ATP Synthase Accumulation in the Central Nervous System of a Woman with Hurler-Scheie Syndrome Treated with Enzyme Replacement Therapy for 12 Years.
Kobayashi H, Ariga M, Sato Y, Fujiwara M, Fukasawa N, Fukuda T, Takahashi H, Ikegami M, Kosuga M1), Okuyama T1)(1National Center for Child Health and Development), Eto Y, Ida H.
JIMD Rep   41 101-107   2018   [Refereed]
Glycogen synthase kinase-3β activity plays a key role in the antitumor effect of nafamostat mesilate in pancreatic cancer cells.
(5) Haruki K, Shiba H, Shimada Y, Shirai Y, Iwase R, Fujiwara Y, Uwagawa T, Ohashi T, Yanaga K.
Ann Gastroenterol Surg   2 65-71   2018   [Refereed]
Hongo K, Ito K, Date T, Anan I, Inoue Y, Morimoto S, Ogawa K, Kawai M, Kobayashi H, Kobayashi M, Ida H, Ohashi T, Taniguchi I, Yoshimura M, Eto Y
124(2) 143-151   2018   [Refereed]

Misc

 
Adenoviral-mediated gene transfer and expression of human beta-glucuronidase gene in the liver,spleen,and central nervoussystem in MPS VII mice.
Proc. Natl. Acad. Sci. USA 1997 ; 94 : 1287-1292   94 : 1287-1292    1997
Efficient and persistend expression of B-glucuronidqse gene in CD34+ cells from human umbilical cord blood by retroviral vector.
Eur. J. Haematol. 1998 ; 61 : 235-239   61 : 235-239    1998
Overexpression of arylsulfatase A gene in fibroblasts from metachromatic leukodystrophy patients dose not induce a new pherotype.
Gene Therapy 1995 ; 2 : 363-368   2 : 363-368    1995
Reduction of lysosomal storage in murine mucopolysaccharidosis type VII by transplanation of normal and genetically modified macrophages.
Blood. 2000 ; 95 : 3631-3633   95 : 3631-3633    2000
Successful transdyction of oligodendrocytes and restoration of arylsulfatase A deficiency in metachromatic leukodystrophy fibroblasts using an adenovirus vector.
Gene Therapy 1995 ; 2 : 443-449   2 : 443-449    1995

Conference Activities & Talks

 
Inhibition of lysosomal enzyme activity enhances antitumor effect of gemcitabine in pancreatic cancer cells. 
Hamura R, Shirai Y, Saito N, Taniai T, Shimada Y, Horiuchi T, Sugano H, Takada N, Kanegae Y, Ohashi T, Yanaga K.
The 14th Annual Academic Surgical Congress   Feb 2019   
Celland Gene Therapy for Lysosomal Storege Disease,
OHASHI Toya
2018 International Joint Conference on Genetics & Medicine   Nov 2018   
Intravenous AAV9-mediated Gene Therapy Ameliorates Neuronal Disease of Mucopolysaccharidosis TypeⅡ.
Miwa S, Shimada Y, Higuchi T, Kobayashi H, Muramatsu S1), Yamagata T1)((1Jichi Medical Univ)), Ohashi T.
The 21st Annual Congress of European Society of Gene and Cell Therapy.   Oct 2018   
Development of HSC mediated gene therapy using ACK2 as preconditioning.
Miwa S, Shimada Y, Higuchi T, Kobayashi H, Ohashi T
The 24th Annual Meeting of Japan Society of Gene and Cell Therapy.   Jul 2018   
Improvement of peripheral neuropathy by intrathecal administration of Adeno-associated virus vector expressing α-galactosidase A in murine Fabry model.
Higuchi T, Shimada Y, Kobayashi H, Fukuda T, Kato F, Ida H, Ohashi T.
The 24th Annual Meeting of Japan Society of Gene and Cell Therapy   Jul 2018   

Research Grants & Projects

 
Gene therapy