KOYASU Shigeo

J-GLOBAL         Last updated: Oct 21, 2019 at 10:44
 
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Name
KOYASU Shigeo
URL
http://www.riken.jp/en/research/labs/ims/immun_cell_sys/
Affiliation
RIKEN
Job title
Executive Director
Degree
Doctor of Science(The University of Tokyo)
Other affiliation
Keio University School of Medicine

Profile

Dr. Shigeo Koyasu received his D.Sc. degree from the University of Tokyo. He worked as Research Associate of the Tokyo Metropolitan Institute of Medical Science, Instructor, and Assistant Professor of the Department of Pathology, Harvard Medical School, Associate Professor of Medicine, Harvard Medical School, and Professor and Chairman of Microbiology and Immunology, Keio University of Medicine, director of RIKEN Center for Integrative Medical Sciences. He is now Executive Director of RIKEN. Dr. Koyasu discovered group 2 innate lymphoid cells (ILC2) originally called as natural helper (NH) cells and has been instrumental in the studies of type 2 innate immune responses in helminth infection and allergic inflammation. He has served as a board member of the Japanese Society for Immunology and the Molecular Biology Society of Japan, a council member of the International Union of Immunological Societies and the president of the Federation of Immunological Societies of Asia and Oceania.

Research Areas

 
 

Academic & Professional Experience

 
Apr 2015
 - 
Today
Executive Director, RIKEN
 
Oct 2014
 - 
Sep 2015
Director, Center for Integrative Medical Sciences (IMS), RIKEN
 
Apr 2013
 - 
Oct 2014
Director (acting), Center for Integrative Medical Sciences (IMS), RIKEN
 
Oct 1995
 - 
Mar 2013
Professor, Department of Microbiology and Immunology, Keio University Scool of Medicine
 
Apr 1995
 - 
Jul 1996
Associate Professor, Department of Medicine, Harvard Medical School
 
Oct 1990
 - 
Mar 1995
Assistant Professor, Department of Pathology, Harvard Medical School
 
Dec 1988
 - 
Sep 1990
Instructor, Department of Pathology, Harvard Medical School
 
May 1988
 - 
Nov 1988
Research Fellow, Laboratory of Immunobiology, Dana-Farber Cancer Institute, Harvard Medical School
 
Nov 1981
 - 
Oct 1991
Research Associate, Department of Cell Biology, Tokyo Metropolitan Institute of Medical Science
 

Education

 
 
 - 
1980
MS, Department of Biophysics and Biochemistry, Faculty of Science, The University of Tokyo Graduate School
 
 
 - 
1978
BS, Department of Biophysics and Biochemistry, Faculty of Science, The University of Tokyo
 

Committee Memberships

 
2017
 - 
Today
Science Council of Japan,  Member
 
2016
 - 
Today
JST,  Senior Fellow
 
2011
 - 
Today
MEXT Council for Science and Technology,  Ad-hoc member
 
2015
 - 
2018
Federation of Immunological Societies in Asia and Oceania (FIMSA),  President
 
2010
 - 
2016
International Union of Immunological Societies (IUIS),  Council member
 
2008
 - 
2013
JSPS Research Center for Science Systems,  Senior
 Program Officer (Medical, Dental and Pharmaceutical Science)
 
2007
 - 
2010
JST Center for Research and Development Strategy,  Fellow (Life Science)
 

Published Papers

 
Sasaki, T., Moro, K., Kubota, T., Kubota, N., Kato, T., Ohno, H., Nakae, S., Saito, H. and Koyasu, S.
Cell Rep.   28: 202-217   Jul 2019   [Refereed]
Koga, S., Hozumi, K., Hirano, K., Yazawa, M., Terooatea, T., Minoda, A., Koyasu, S. and Moro, K.
J. Exp. Med.   215: 1609-1626   May 2018   [Refereed]
Namkoong, H., Ishii, M., Fujii, H., Yagi, K., Asami, T., Asakura, T., Suzuki, S., Hegab, A. E., Kamata, H., Tasaka, S., Atarashi, K., Nakamoto, N., Honda, K., Kanai, T., Hasegawa, N., Koyasu, S. and Betsuyaku, T.
PLoS Pathog.   14: e1006955   Apr 2018   [Refereed]
The FANTOM5 consortium
Sci. Data   4: 170112   Aug 2017   [Refereed]
Kurebayashi, Y., Baba, Y., Minowa, A., Nadya, N. A., Yoshimura, A., Koyasu, S. and Nagai, S.
Biochem. Biophys. Res. Commun.   480: 114-119   Oct 2016   [Refereed]
Shiono, Y., Ishii, K., Nagai, S., Kakinuma, H., Sasaki, A., Funao, H., Kuramoto, T., Yoshioka, K., Ishihama, H., Isogai, N., Tskeshima, K., Tsuji, T., Okada, Y., Koyasu, S., Nakamura, M., Toyama, Y., Aizawa, M. and Matsumoto, M.
Sci. Rep.   6: 32758   Sep 2016   [Refereed]
Yamazumi, Y., Sasaki, O., Imamura, M., Oda, T., Ohno, Y., Shiozaki-Sato, Y., Nagai, S., Suyama, S., Kamoshita, Y., Funato, K., Yasui, T., Kikutani, H., Yamamoto, K., Dohi, M., Koyasu, S. and Akiyama, T.
Cell Rep.   16: 2456-2471   Aug 2016   [Refereed]
Funao, H., Nagai, S., Sasaki, A., Hoshikawa, T., Tsuji, T., Okada, Y., Koyasu, S., Toyama, Y., Nakamura, M., Aizawa, M., Matsumoto, M. and Ishii, K.
Sci. Rep.   6: 23238   Mar 2016   [Refereed]
Moro, K., Kabata, H., Tanabe, M., Koga, S., Takeno, N., Mochizuki, M., Fukunaga, K., Asano, K., Betsuyaku, T. and Koyasu S.
Nat. Immunol.   17: 76-86   Nov 2015   [Refereed]
Seed, T. M., Xiao, S., Manley, N., Nikolich-Zugich, J., Pugh, J., Vandenbrink, M. R. M., Hirabayashi, Y., Yasutomo, K., Iwama, A., Koyasu, S., Shterev, I., Sempowski, G., Macchiarini, F., Nakachi, K., Kunugi, K., Hammer, C. and DeWerd, L.
Int. J. Rad. Biol.   92: 59-70   Nov 2015   [Refereed]
Arai, Y., Martin-Ruiz, C. M., Takayama, M., Abe, Y., Takebayashi, T., Koyasu, S., Suematsu, M., Hirose, N. and von Zglinicki, T.
EBioMedicine   2: 1549-1558   Jul 2015   [Refereed]
Morita, H., Arae, K., Unno, H., Miyauchi, K., Toyama, S., Nambu, A., Oboki, K., Ohno, T., Moromura, K., Matsuda, A., Yamaguchi, S., Narushima, S., Kajiwara, N., Iikura, M., Suto, H., McKenzie, A. N., Takahashi, T., Karasuyama, H., Okumura, K., Azuma, M., Moro, K., Akdis, C., Galli, S. J., Koyasu, S., Kubo, M., Sudo, K., Saito, H., Matsumoto, K. and Nakae, S.
Immunity   43: 175-186   Jul 2015   [Refereed]
Vasanthakumar, A., Moro, K., Xin, A., Liao, Y, Gloury, R., Kawamoto, S., Fagarasan, S., Mielke, L. A., Afshar-Sterle, S., Seth L. Masters, S. L., Nakae, S., Saito, H., Wentworth, J. M., Li, P., Liao, W., Leonard, W. J., Smyth, G. K., Shi, W., Nutt, S. L., Koyasu, S. and Kallies, A.
Nat. Immunol.   16: 276-285   Jan 2015   [Refereed]
Yoshioka, K., Ishii, K., Kuramoto, T., Nagai, S., Funao, H., Ishihama, H., Shiono, Y., Sasaki, A., Aizawa, M., Okada, Y., Koyasu, S., Toyama, Y. and Matsumoto, M.
PLoS One   9: e106367   Sep 2014   [Refereed]
Motomura, Y., Morita, H., Moro, K., Nakae, S., Artis, D., Endo, T. A., Kuroki, Y., Ohara, O., Koyasu, S. and Kubo, M.
Immunity   40: 758-771   May 2014   [Refereed]
Yasui, F., Kohara, M., Kitabatake, M., Nishiwaki, T., Fujii, H., Tateno, C., Yoneda, M., Morita, K., Matsushima, K., Koyasu, S. and Kai, C.
Virology   454-455: 157-168   Mar 2014   [Refereed]
The FANTOM consortium
Nature   507: 462-470   Mar 2014   [Refereed]
Shirakabe, K., Shibagaki, Y., Yoshimura, A., Koyasu, S. and Hattori, S.
J. Proteomics   98: 233-243   Jan 2014   [Refereed]
Kabata, H., Moro, K., Fukunaga, K., Suzuki, Y., Miyata, J., Masaki, K., Betsuyaku, T., Koyasu, S. and Asano K.
Nat. Commun.   4: 2675   Oct 2013   [Refereed]
Nishimura, T., Zhao, X., Gan, H., Koyasu, S. and Remold, H. G.
FASEB J.   27: 3827-3836   Jun 2013   [Refereed]

Misc

 
Wagner, M. and Koyasu, S.
Trends Immunol.   40: 415-430   Apr 2019   [Refereed]
Kabata, H., Moro, K. and Koyasu, S.
Immunol. Rev.   286: 37-52   Oct 2018   [Refereed][Invited]
Vivier, E., Artis, D., Colonna, M., Diefenbach, A., Di Santo, J. P., Eberl, G., Koyasu, S., Locksley, R. M., McKenzie, A. N. J., Mebius, R. E., Powrie, F. and Spits, H.
Cell   174: 1054-1066   Aug 2018   [Refereed]
Ealey, K. N., Moro, K. and Koyasu, S.
Immunol. Rev.   278: 207-218   Jul 2017   [Refereed][Invited]
Wagner, M., Moro, K. and Koyasu, S.
Trends Cancer   5: 326-335   May 2017   [Refereed]
Ealey, K. N. and Koyasu, S.
Immunity   46: 10-13   Jan 2017   [Invited]
Morita, H., Moro, K. and Koyasu S.
J. Allergy Clin. Immunol.   138 1253-1264   Nov 2016   [Refereed]
Kabata, H., Moro, K., Koyasu, S. and Asano K.
Allergol. Int.   64: 227-234   Jul 2015   [Refereed][Invited]
Moro, K., Ealey, K. N., Kabata, H. and Koyasu S.
Nat. Protoc.   10: 792-806   May 2015   [Refereed]
Koyasu, S.
Nat. Immunol.   16: 133-134   Feb 2015   [Invited]
Moro, K. and Koyasu, S.
Semin. Immunopathol.   37: 27-37   Jan 2015   [Refereed][Invited]
Diefenbach, A., Colonna, M. and Koyasu, S.
Immunity   41: 354-365   Sep 2014   [Refereed]
Koyasu, S. and Moro, K.
Ann. N. Y. Acad. Sci.   1283: 43-49   Apr 2013   [Refereed][Invited]
Kurebayashi, Y., Nagai, S., Ikejiri, A. and Koyasu, S.
Genes Cells   18: 247-265   Apr 2013   [Invited]
Nagai, S., Kurebayashi, Y. and Koyasu, S.
Ann. N. Y. Acad. Sci.   1280: 30-34   Mar 2013   [Refereed][Invited]
Spits, H., Artis, D., Colonna, M., Diefenbach, A., Di Santo, J. P., Eberl, G., Koyasu, S., Locksley, R. M., McKenzie, A. N., Mebius, R. E., Powrie, F. and Vivier, E.
Nat. Rev. Immunol.   13: 145-149   Feb 2013   [Refereed][Invited]
Koyasu S.
Cornea   31: S20-S24   Nov 2012   [Invited]
Koyasu, S. and Moro, K.
Front. Immunol.   3: 101   May 2012   [Refereed][Invited]
Koyasu, S. and Moro, K.
Immunity   36: 317-319   Mar 2012   [Invited]
Koyasu, S. and Moro, K.
Immunology   132: 475-481   Apr 2011   [Invited]

Teaching Experience

 
 

Patents

 
#7,667,088 B2 : Autoimmune disease model animal
AMAGAI Masayuki, NISHIKAWA Takeji, SUZUKI Harumi, KOYASU Shigeo
#7,550,562 B2 : Pemphigus monoclonal antibody
TSUNODA Kazuyuki, AMAGAI Masayuki, NISHIKAWA Takeji, KOYASU Shigeo
#8,524,250 B2 : Carrier
KOYASU Shigeo, NAGAI Shigenori, SASAKAWA Chihiro, MIMURO Hitomi