2001年12月
The actin-depolymerizing factor destrin has an actin-stabilizing domain
BIOCHEMISTRY AND CELL BIOLOGY
- ,
- ,
- ,
- ,
- 巻
- 79
- 号
- 6
- 開始ページ
- 773
- 終了ページ
- 778
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- 出版者・発行元
- CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
Destrin is a 19 kDa actin-depolymerizing protein of the ADF-cofilin family. Destrin was digested with trypsin to a structurally stable 9.2 kDa fragment that contains the actin-binding sequence. The purified 9.2 kDa fragment has an actin filament stabilizing activity, rather than an actin filament depolymerizing activity. The deleted region is probably essential for the actin filament depolymerizing activity of intact destrin. Surprisingly, the 9.2 kDa fragment also has an assembly-promoting activity in the absence of ATP.
- リンク情報
- ID情報
-
- ISSN : 0829-8211
- eISSN : 1208-6002
- Web of Science ID : WOS:000172572800010