NOGUCHI Satoru

J-GLOBAL         Last updated: Nov 8, 2018 at 16:31
 
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Name
NOGUCHI Satoru
Affiliation
National Center of Neurology and Psychiatry
Section
National Institute of Neuroscience,Ncnp
Job title
Section Chief
Degree
Doctor of Science

Research Areas

 
 

Academic & Professional Experience

 
1993
   
 
Postdoctoral Fellow, National Institute of
 
 
   
 
Neuroscience, NCNP
 
1995
   
 
COE Postdoctoral Fellow, National Institute of
 
 
   
 
Neuroscience, NCNP
 
1996
   
 
Researcher, PRESTO, JST
 

Education

 
 
   
 
Graduate School, Division of National Science and Technology, Chiba University
 
 
   
 
Department of Chemistry, Faculty of Science, Chiba University
 

Published Papers

 
Small-Vessel Vasculopathy Due to Aberrant Autophagy in LAMP-2 Deficiency.
Nguyen HT, Noguchi S, Sugie K, Matsuo Y, Nguyen CTH, Koito H, Shiojima I, Nishino I, Tsukaguchi H
Sci Rep   8(1) 3326-3326   Feb 2018   [Refereed]
Genetic diagnosis of Duchenne/ Becker muscular dystrophy using next-generation sequencing: validation analysis of DMD mutations.
Okubo M, Minami N, Goto K, Goto YI, Noguchi S, Mitsuhashi S, Nishino I
J Hum Genet.   62(10) 931-933   Oct 2017   [Refereed]
IBA57 mutations abrogate iron-sulfur cluster assembly leading to cavitating leukoencephalopathy.
Ishiyama A, Sakai C, Matsushima Y, Noguchi S, Mitsuhashi S, Endo Y, Hayashi YK, Saito Y, Nakagawa E, Komaki H, Sugai K, Sasaki M, Sato N, Nonaka I, Goto YI, Nishino I
Neurol Genet.   3(5) e184-e184   Sep 2017   [Refereed]
Sialic acid deficiency is associated with oxidative stress leading to muscle atrophy and weakness in the GNE myopathy.
NOGUCHI Satoru
Hum Mol Genet.   26(16) 3081-3093   Aug 2017   [Refereed]
Comprehensive analysis for genetic diagnosis of Dystrophinopathies in Japan.
Okubo M, Goto K, Komaki H, Nakamura H, Mori-Yoshimura M, Hayashi YK, Mitsuhashi S, Noguchi S, Kimura E, Nishino I
Orphanet J Rare Dis   12(1) 149-149   Aug 2017   [Refereed]

Books etc

 
Autophagy in GNE myopathy. Autophagy – A Double-Edged Sword – Cell Survival or Death?
Cho A, Noguchi S (Part:Joint Work)
InTech   2013   

Conference Activities & Talks

 
Muscle growth by activin type II receptor blocking ameliorates weakness in GNE myopathy mice.
Miyakawa M, Yonekawa T, Malicdan MC, Lach-Trifilieff E, Nonaka I, Nishino I, Noguchi S
22nd International Congress of the World Muscle Society   5 Oct 2017   
Tubular aggregate myopathy with dystrophic features.
Lee J, Yoshimura M, Hirano R, Miyatake W, Koshimizu E, Matsumoto N, Mori H, Tachii N, Suzuki M, Ogata K, Nishino I, Noguchi S
22nd International Congress of the World Muscle Societ   4 Oct 2017   
Comprehensive analysis: nonsense mutation induced exon skipping in Becker muscular dystrophy.
Okubo M, Noguchi S, Kimura E, Mitsuhashi S, Nishino I
22nd International Congress of the World Muscle Society   4 Oct 2017   
Integrated genome analysis of COX deficiency in Japan.
Takayama K, Iida A, Noguchi S, Nonaka I, Goto Y, Nishino I
22nd International Congress of the World Muscle Society   4 Oct 2017   
Comprehensive genome analysis of Japanese patients with myofibrillar myopathy.
Inoue M, Iida A, Noguchi S, Nonaka I, Nishino I
22nd International Congress of the World Muscle Society   4 Oct 2017   

Research Grants & Projects

 
Japan Agency for Medical Research and Development: Practical Research Project for Rare / Intractable Diseases
Project Year: Apr 2017 - Mar 2020    Investigator(s): NISHINO Ichizo
Japan Agency for Medical Research and Development: Research and Development Grants for Comprehensive Research for Persons with Disabilities
Project Year: Apr 2016 - Mar 2019    Investigator(s): NOGUCHI Satoru
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (B)
Project Year: Apr 2015 - Mar 2018    Investigator(s): NOGUCHI Satoru
National Center of Neurology and Psychiatru: Intramural Research Grant (28-6) for Neurological and Psychiatric Disorders of NCNP
Project Year: Apr 2015 - Mar 2018    Investigator(s): TAKEDA Shin'ichi
Molecular Mechanism Causing Muscular Dystrophy

Patents

 
特開2011-513374 : THERAPEUTIC PHARMACEUTICAL AGENT FOR DISEASES ASSOCIATED WITH DECREASE IN FUNCTION OF GNE PROTEIN, FOOD COMPOSITION, AND FOOD ADDITIVE
NOGUCHI Satoru