MISC

2003年5月

Sequence analysis of the medium RNA segment of three Simbu serogroup viruses, Akabane, Aino, and Peaton viruses

VIRUS RESEARCH
  • T Yanase
  • ,
  • K Yoshida
  • ,
  • S Ohashi
  • ,
  • T Kato
  • ,
  • T Tsuda

93
1
開始ページ
63
終了ページ
69
記述言語
英語
掲載種別
DOI
10.1016/S0168-1702(03)00066-2
出版者・発行元
ELSEVIER SCIENCE BV

The sequence analysis was carried out for the medium (M) RNA segment of the Akabane virus (AKAV), Aino virus (AINV), and Peaton virus (PEAV) of the Simbu serogroup of the genus Orthobunyavirus of the family Bunyaviridae. The complementary sequences of the M RNA segments of AKAV, AINV, and PEAV contain a single large open reading frame (ORF), like other orthobunyaviruses. The ORFs potentially encode 1401 amino acids (aa), 1404 aa, and 1400 aa polypeptides, respectively. The identity of the M segment among these viruses is remarkably low, although previous researchers reported that the small RNA segments are highly conserved. Because the M segment codes for the viral surface glycoproteins G1 and G2, the variability of the M segment may affect the antigenicity of these viruses. Phylogenetic studies based on the M and S segment sequences suggested that genetic reassortment has been occurring among ancestral viruses of the three Simbu serogroup viruses throughout their evolution. (C) 2003 Elsevier Science B.V. All rights reserved.

Web of Science ® 被引用回数 : 25

リンク情報
DOI
https://doi.org/10.1016/S0168-1702(03)00066-2
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000182868300007&DestApp=WOS_CPL

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