MISC

2007年12月

Genetic diversity and reassortments among Akabane virus field isolates

VIRUS RESEARCH
  • Takahiko Kobayashi
  • ,
  • Tohru Yanase
  • ,
  • Makoto Yamakawa
  • ,
  • Tomoko Kato
  • ,
  • Kazuo Yoshida
  • ,
  • Tomoyuki Tsuda

130
1-2
開始ページ
162
終了ページ
171
記述言語
英語
掲載種別
DOI
10.1016/j.virusres.2007.06.007
出版者・発行元
ELSEVIER SCIENCE BV

Sequencing and phylogenetic analysis were carried out for 35 Akabane virus (AKAV) field isolates collected from Japan, Taiwan, Australia and Kenya, and for one Tinaroo virus (TINV). Of the three RNA segments, the M RNA segment encoding the glycoproteins that induce neutralization antibodies was the most variable among the isolates. The difference in the M RNA segments among Asian (Japanese and Taiwanese) isolates was not large (<12.3% nucleotide (nt) and <5.9% amino acid (aa) differences), rather than those between Asian and Australian isolates (13.4-14.9% nt and 6.2-8.2% aa difference). In phylogenetic trees, the Australian isolates form a separate branch from Asian isolates. All three RNA segments of the Kenyan isolate MP496 were genetically distant from those of the other AKAV field isolates. Although the S and L RNA segments of TINV, which is regarded as a strain of AKAV, was closely related to those of the Asian and Australian AKAV isolates, the M RNA was divergent that of the most distant AKAV isolate, MP496. Discrepancies among the phylogenetic trees of the S, M and L RNA segments indicate genomic reassortment events among AKAV field isolates. (c) 2007 Elsevier B.V. All rights reserved.

Web of Science ® 被引用回数 : 34

リンク情報
DOI
https://doi.org/10.1016/j.virusres.2007.06.007
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000251480800018&DestApp=WOS_CPL

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