MAIKO KAWAGUCHI

Profile Information

Affiliation: (Associate Professor), School of Agriculture, Undergraduate School

Degree: PhD(Mar, 2001, Yokohama City University)

J-GLOBAL ID: 200901098388277228
researchmap Member ID: 5000004204

External link: http://www.isc.meiji.ac.jp/~maiko/English/Index_English.html

Research Interests

Research Areas

Research History

Apr, 2019 - Present

School of Agriculture, Meiji University

Education

Apr, 1997 - Mar, 2001

Graduate School, Division of Medicine, Yokohama City University
Apr, 1991 - Mar, 1997

Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology

Papers

Bidirectional effects of voluntary exercise on the expression of Bdnf isoforms in the hippocampus of Hatano rat strains displaying different activity levels

Shuichi Chiba, Hikaru Asano, Shogo Moriya, Taichi Hatakeyama, Shohei Kobayashi, Ryo Ohta, Maiko Kawaguchi

Neuropsychopharmacology Reports, 43(1) 126-131, Jan 17, 2023
Alterations between high and low-avoidance lines of Hatano rats in learning behaviors, ultrasonic vocalizations, and histological characteristics in hippocampus and amygdala

Shuichi Chiba, Toru Okawara, Kotaro Kawakami, Ryo Ohta, Maiko Kawaguchi

Physiology & Behavior, 245 113670-113670, Mar, 2022 Peer-reviewed
Novel toxicity of tris(1,3-dichloro-2-propyl) phosphate in adult male rats

Shohei Kobayashi, Kodai Abe, Anna Isobe, Airi Nakayama, Takahiro Akimoto, Taichi Hatakeyama, Yoshiaki Saito, Rie Yanagisawa, Eiko Koike, Noriyuki Suzuki …

Journal of Applied Toxicology, Sep, 2020 Peer-reviewed
Repressor Element 1 Silencing Transcription factor /Neuron-Restrictive Silencing Factor (REST/NRSF) in Social Stress and Depression

Soga T, Nakajima S, Kawaguchi M, Parhar IS.

Prog Neuropsychopharmacol Biol Psychiatry, Jul, 2020 Peer-reviewed
The impact of oral exposure to low dose tris(2-butoxyethyl)phosphate in allergic asthmatic mice

Yanagisawa R, Koike E, Win-Shwe TT, Kawaguchi M, Takano H

Journal of Applied Toxicology, Jun, 2020 Peer-reviewed
The effects of 28-day early-life exposure to triphenyl phosphate (TPhP) on odor preference and sexual behavior in female rats.

Nakayama, A., Hattori, T., Isobe, A., Kobayashi, S., Suzuki, G. …

Journal of Applied Toxicology, Jun, 2020 Peer-reviewed
Relationship between motor function and ultrasonic vocalizations induced by maternal separation in rat pups.

Isobe, A. and Kawaguchi, M.

The Journal of Veterinary Medical Science, 81(2) 287-293, Feb, 2019 Peer-reviewed
Hatano rats are a suitable metabolic syndrome model for studying feeding behavior, blood pressure levels, and percent body fat

Anna ISOBE, Tsutomu SHIMADA, Masaki ABURADA, Rie YANAGISAWA, Tomoyoshi SAKAWA, Takahiro NAKAMURA, Toshiyuki HIMI, Ryo OHTA, Maiko KAWAGUCHI

The Journal of Veterinary Medical Science, 81(1) in press, Nov, 2018 Peer-reviewed
Testing Animal Anxiety in Rats: Effects of Open Arm Ledges and Closed Arm Wall Transparency in Elevated Plus Maze Test

Horii Y, McTaggart, Kawaguchi M

JoVE, 29(136), Jun, 2018 Peer-reviewed
Male Hatano low-avoidance rats show more active sexual behavior with lower plasma testosterone than high-avoidance rats

Nakayama A, Okawa H, Zheng M, Pu S, Watanabe G, Ohta R, Kawaguchi M

J Vet Med Sci., 80(7) 1179-1182, May, 2018 Peer-reviewed
Early-life exposure to Tris(1,3-dichloroisopropyl) phosphate induces dose-dependent suppression of sexual behavior in male rats.

Manami Kamishima, Tatsuya Hattori, Go Suzuki, Hidenori Matsukami, Chiaki Komine, Yasuyuki Horii, Gen Watanabe, Takumi Oti, Hirotaka Sakamoto, Tomoko Soga …

Journal of applied toxicology : JAT, 38(5) 649-655, May, 2018 Peer-reviewed
Effects of neonatal 17α-ethinyloestradiol exposure on female-paced mating behaviour in the rat.

Komine C, Nakajima S, Kondo Y, Horii Y, Yoshida M, Kawaguchi M.

J Appl Toxicol., 37(8) 996-1003, Feb, 2017 Peer-reviewed
A Single Neonatal Injection of Ethinyl Estradiol Impairs Passive Avoidance Learning and Reduces Expression of Estrogen Receptor a in the Hippocampus and Cortex of Adult Female Rats

Tatsuomi Shiga, Takahiro J. Nakamura, Chiaki Komine, Yoshikuni Goto, Yasushi Mizoguchi, Midori Yoshida, Yasuhiko Kondo, Maiko Kawaguchi

PLOS ONE, 11(1), Jan, 2016 Peer-reviewed
Higher detection sensitivity of anxiolytic effects of diazepam by ledge-free open arm with opaque walled closed arm elevated plus maze in male rats

Yasuyuki Horii, Maiko Kawaguchi

BEHAVIOURAL BRAIN RESEARCH, 294(Nov 1) 131-140, Nov, 2015 Peer-reviewed
Dietary deprivation of each essential amino acid induces differential systemic adaptive responses in mice

Shotaro Kamata, Junya Yamamoto, Kenta Kamijo, Takahito Ochiai, Tamako Morita, Yurika Yoshitomi, Yoshifumi Hagiya, Masashi Kubota, Rika Ohkubo, Maiko Kawaguchi …

MOLECULAR NUTRITION & FOOD RESEARCH, 58(6) 1309-1321, Jun, 2014 Peer-reviewed
生後24時間以内のethinyl estradiol曝露は成熟後の脳内ERα発現量を減少させる

志賀健臣, 中村孝博, 小峰千亜希, 神島愛未, 後藤芳邦, 吉田緑, 近藤保彦, 溝口康, 川口真以子

日本内分泌かく乱化学物質学会研究発表会要旨集, 16th 130, Dec, 2013
Male Hatano High-Avoidance Rats Show High Avoidance and High Anxiety-Like Behaviors as Compared with Male Low-Avoidance Rats

Yasuyuki Horii, Maiko Kawaguchi, Ryo Ohta, Akihiro Hirano, Gen Watanabe, Nobumasa Kato, Toshiyuki Himi, Kazuyoshi Taya

EXPERIMENTAL ANIMALS, 61(5) 517-524, Oct, 2012 Peer-reviewed
Neonatal exposure to a low dose of ethynyl estradiol affects sexual behavior

KOMINE Chiaki, KONDO Yasuhiko, ODASHIMA Yumeka, UEMURA Hanae, SENBON Takasi, KAWAGUCHI Maiko

The Journal of Reproduction and Development Supplement, 105 1014-1014, 2012
Male Hatano high-avoidance rats show high avoidance and high anxiety-like behaviors as compared with male low-avoidance rats

Yasuyuki Horii, Maiko Kawaguchi, Ryo Ohta, Akihiro Hirano, Gen Watanabe, Nobumasa Kato, Toshiyuki Himi, Kazuyoshi Taya

Experimental Animals, 61(5) 517-524, 2012
Maternal Exposure to Isobutyl-Paraben Impairs Social Recognition in Adult Female Rats

Maiko Kawaguchi, Kaori Morohoshi, Hideki Imai, Masatoshi Morita, Nobumasa Kato, Toshiyuki Himi

EXPERIMENTAL ANIMALS, 59(5) 631-635, Oct, 2010

Misc.

Early-life exposure to Tris(1,3-dichloroisopropyl) phosphate (TDCIPP) induces dose-dependent suppression of sexual behavior in male rats

Kamishima M, Hattori T, Suzuki G, Matsukami H, Komine C, Horii Y, Watanabe G, Oti T, Sakamoto H, Soga T …

Journal of Applied Toxicology, 35(8) 472-483, 2018
幼若期tris(1,3-dichloroisopropyl)phosphate(TDCIPP)とtriphenyl phosphate(TPhP)曝露は雄ラットの性行動へ濃度依存的な抑制効果をもつ

服部達哉, 神島愛未, 鈴木剛, 松神秀徳, 渡辺元, 近藤保彦, 滝上英孝, 川口真以子

環境ホルモン学会研究発表会プログラム・要旨集, 19th, 2016
Behavioral profile in ovariectomized female Hatano high- and low-avoidance rats

Maiko Kawaguchi, Ryo Ohta, Hiroko Makihara, Gen Watanabe, Kazuyoshi Taya, Tsutomu Shimada, Masaki Aburata, Nobumasa Kato, Toshiyuki Himi

ENDOCRINE JOURNAL, 57 S527-S527, Mar, 2010
Behavioral profiles of HATANO rats

Toshiyuki Himi, Maiko Kawaguchi, Kaori Morohoshi, Gen Watanabe, Kazuyoshi Taya, Masatoshi Morita, Yasuhiko Kondo, Hideki Imai, Nobumasa Kato

NEUROSCIENCE RESEARCH, 68 E204-E204, 2010
Maternal isobutyl-paraben induce obesity in female rats

Maiko Kawaguchi, Kaori Morohoshi, Gen Watanabe, Yasuyuki Horii, Kazuyoshi Taya, Masatoshi Morita, Hideki Imai, Nobumasa Kato, Toshiyuki Himi

JOURNAL OF PHYSIOLOGICAL SCIENCES, 60 S195-S195, 2010
Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor beta 1 and synapsin I in rats cerebral cortex

Maiko Kawaguchi, Kaori Morohoshi, Erina Saita, Rie Yanagisawa, Gen Watanabe, Hirohisa Takano, Masatoshi Morita, Hideki Imai, Kazuyoshi Taya, Toshiyuki Himi

JOURNAL OF PHARMACOLOGICAL SCIENCES, 109 192P-192P, 2009
Developmental exposure to pentachlorophenol affects thyroid hormone responsive gene in the brain but not stress response

Maiko Kawaguchi, Kaori Morohoshi, Rie Yanagisawa, Erina Saita, Gen Watanabe, Masatoshi Morita, Kazuyoshi Taya, Hirohisa Takano, Toshiyuki Himi, Hideki Imai

NEUROSCIENCE RESEARCH, 55 S166-S166, 2006
Effects of bisphenol a on the progesterone receptor system in the adult female rat brain.

T Funabashi, A Sano, D Mitsushima, M Kawaguchi, F Kimura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 91 34P-34P, 2003
脳の記憶学習を,制御するニューロステロイド,変動させる環境ホルモン内分泌攪乱物質の中枢神経系に及ぼす作用

舩橋利也, 美津島大, 佐野由加根, 中村孝博, 川口真以子, 貴邑冨久子

生化学, 74(8) 636-636, Aug, 2002
内分泌撹乱物質の中枢作用に関する研究の現在・未来内分泌攪乱物質が脳に及ぼすエストロジェニック作用とノン・エストロジェニック作用

舩橋利也, 川口真以子, 中村孝博, 貴邑冨久子

日本内分泌学会雑誌, 78(1) 19-19, Apr, 2002
胎生期および授乳期にBisphenol Aを曝露されたラットの血清甲状腺ホルモン濃度

川口真以子, 森田昌敏, 今井秀樹, 舩橋利也, 美津島大, 貴邑冨久子

環境ホルモン学会研究発表会要旨集, 4回 359-359, Dec, 2001
卵巣摘除成熟ラットの視床下部プロジェステロン受容体発現に及ぼすビスフェノールAの影響

舩橋利也, 川口真以子, 貴邑冨久子

神経化学, 40(2-3) 466-466, Sep, 2001
視床下部プロジェステロン受容体(PR)mRNA発現に及ぼす内分泌攪乱物質の影響

舩橋利也, 川口真以子, 佐野亜加根, 貴邑冨久子

日本内分泌学会雑誌, 77(2) 312-312, Sep, 2001
内分泌攪乱物質のパルス状黄体形成ホルモン(LH)分泌に及ぼす影響

舩橋利也, 川口真以子, 貴邑冨久子

日本生気象学会雑誌, 36(3) S39-S39, Oct, 1999
卵巣摘除ラットのパルス状LH分泌に対する内分泌攪乱物質の影響

川口真以子, 舩橋利也, 饗庭祥子, 貴邑冨久子

日本内分泌学会雑誌, 75(1) 155-155, Apr, 1999

Books and Other Publications

脳を攻撃する環境ホルモン

貴邑冨久子, 舩橋利也, 川口真以子 (Role: Joint author)

藤原書店, Feb, 2001

Presentations

リン酸トリス(1,3-ジクロロ-2-プロピル)の混餌経口曝露がアレルギー性喘息マウスモデルの肺炎症に及ぼす影響

柳澤利枝, 小池英子, Tin-Tin Win-Shwe, 川口真以子, 嶋田努, 高野裕久

第27回日本免疫毒性学会学術年会, Sep 26, 2020, 日本免疫毒性学会
Tris(1,3-dichloro-2-propyl)phosphate(TDCIPP)の幼若期曝露は成熟期曝露後の毒性影響に変化を及ぼすか

秋元貴尋, 小林翔平, 磯部翔一, 畠山太一, 太田亮, 柳澤利枝, 小池英子, 鈴木規之, 川口真以子

第64回日本薬学会関東支部大会, Sep 19, 2020, 日本薬学会
Tris(1,3-dichloro-2-propyl)phosphate(TDCIPP)の幼若期、成熟期2回曝露が成熟期雄ラットに及ぼす毒性影響

秋元貴尋, 小林翔平, 磯部翔一, 畠山太一, 太田亮, 柳澤利枝, 小池英子, 鈴木規之, 川口真以子

第47回日本毒性学会学術年会, Jun 29, 2020, 日本毒性学会
4Tris (1,3-dichloro-2-propyl) phosphate の 7 日間反復経口投与が成熟期雄ラットに及ぼす毒性影響

小林翔平・阿部光海・大沼愛美・畠山太一・河野菜摘子・宮戸健二・斉藤義明・柳澤利枝・小池英子・鈴木規之・川口真以子

第22回環境ホルモン学会研究発表会, Dec 12, 2019, 日本内分泌撹乱化学物質学会
災害・事故と非定常曝露に対するリスク評価手法

鈴木規之, 小池英子, 柳澤利枝, 川口真以子

2019年度第32 回日本リスク学会年次大会, Nov 22, 2019, 日本リスク学会
アオウミガメ小笠原諸島個体群において日陰がウミガメ幼体の特性に与える影響について

小林翔平, 遠藤大輔, 近藤理美, 北山知代, 新井克彦, 渡辺元, 川口真以子

第30回日本ウミガメ会議, Nov 15, 2019, 日本ウミガメ協議会
The effect of environmental enrichment on hippocampal neuroplasticity-related genes in Hatano rats.

Asano, H., Okawa, H., Nakayama, A., Tokuoka, H., Kasai, W., Ota, R. and Kawaguchi, M

Society for Neuroscience 2019., Oct 19, 2019, Society for Neuroscience
Sutability of sociality research using Hatano rats

Abe, K., Endo, S., Yanagisawa, R., Ota, R. and Kawaguchi, M

Society for Neuroscience 2019., Oct 19, 2019, Society for Neuroscience
Genetic and Endocrinological Analysus of Stress Response and Angsiety-Like Behaviour by Cross-Fostered Hatano Rats

Akimoto, T., Kawakami, K., Ichikawa, M., Horii, Y., Nakajima, S., Hatakeyama, T., Tokuoka, H., Ota, R., Soga, T., Ishwar S Parhar. and Kawaguchi, M

Society for Neuroscience 2019., Oct 19, 2019, Society for Neuroscience
Hatano高回避系(HAA)及び低回避系(LAA)ラットは養母交換により不安様行動・ストレス内分泌応答が変化する

堀井康行・川上光太郎・徳岡秀代・太田亮・田谷一善・川口真以子

第162回日本獣医学会学術集会, Sep 10, 2019, 日本獣医学会
Hatano ラットの社会性再認記憶の系統差の検討

畠山太一, 川上光太郎, 大河原利, 武者晃司, 太田亮, 川口真以子

第42回日本神経科学大会, Jul 25, 2019, 日本神経科学学会
The Effects of Environmental Enrichment on Anxiety-Like Behavior, Learning Behavior and Hippocampal Gene Expression in Hatano Rats.

Asano, H., Nakayama, A., Okawa, H., Tokuoka, H., Ota, R., Kasai, W. and Kawaguchi, M

The 14th International Conference on Environmental Enrichment (ICEE KYOTO 2019)., Jun 22, 2019
Effect of Environmental Enrichment on Reproductive Behavior in Hatano Rats.

Okawa, H., Ota, R., Nakayama, A., Asano, H., Kasai, W., Kobayashi, S. and Kawaguchi, M

The 14th International Conference on Environmental Enrichment (ICEE KYOTO 2019)., Jun 22, 2019
文脈恐怖条件づけ場面におけるHatanoラットの特徴

畠山太一・大河原利・太田亮・川口真以子

第37回日本生理心理学会大会, May 25, 2019, 日本生理心理学会
Tris (1,3-dichloro-2-propyl) Phosphate (TDCIPP) の幼若期・成熟期曝露の毒性影響

中山愛里, 磯部安奈, 阿部光海, 坂井亮太, 白藤勇登, 柳澤利枝, 小池栄子, 鈴木規之, 川口真以子.

環境ホルモン学会第12回研究発表会, Dec 15, 2018, 環境ホルモン学会第12回研究発表会
幼若期Hatanoラットの社会性の獲得・発達の特徴

阿部光海, 服部達哉, 前田侑乃, 柳澤利枝, 太田亮, 川口真以子

第161回日本獣医学会学術集会, Sep 11, 2018
The effects of environmental enrichment on anxiety-like behavior and hippocampal gene expression in Hatano rats.

Hikaru Asano, Airi Nakayama, Hasuka Okawa, Hideyo Tokuoka, Ryo Ota, Maiko Kawaguchi

The 78th Annual Meeting of the Japanese Society for Animal Psychology, Aug 28, 2018
Social companions may affect rat pup physical strength and anxiety calls

Anna Isobe, Maiko Kawaguchi

The 78th Annual Meeting of the Japanese Society for Animal Psychology, Aug 28, 2018
Influence of Cross-Fostering on Anxiety-Like Behavior and Expression of Wnt3a Gene in Hippocampus in Hatano Rats

Kotaro Kawakami, Shingo Nakazima, Tomoko Soga, Ishwar S Parhar, Ryo Ohta, Maiko Kawaguchi

The 78th Annual Meeting of the Japanese Society for Animal Psychology, Aug 28, 2018
Effect of environmental enrichment on reproductive behavior and body weight in Hatano rats

Airi Nakayama, Hasuka Okawa, Hikaru Asano, Hideyo Tokuoka, Ryo Ohta, Maiko Kawaguchi

The 78th Annual Meeting of the Japanese Society for Animal Psychology, Aug 28, 2018

Research Projects

室内ダスト中の化学物質曝露による腸内細菌叢の変化は生体高次機能をかく乱し得るか

基盤研究B（一般）, Apr, 2017 - Mar, 2020

国立研究開発法人国立環境研究所柳澤利枝
製品に含まれる化成品及び不純物に由来する有害廃棄物対策と循環方策構築に向けた研究

独立行政法人環境再生保全機構, Apr, 2013 - Mar, 2015

国立研究開発法人国立環境研究所滝上英孝
Identification of in vitro reproductive toxicants in house and office environments

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, Nov, 2011 - Mar, 2014

SUZUKI Go, KAWAGUCHI Maiko
内分泌かく乱化学物質が甲状腺機能とストレス応答に及ぼす影響の検証

特別研究員奨励費, Apr, 2003 - Mar, 2006

川口真以子

Profile Information

Research Interests

Research Areas

Research History

Education

Papers

Misc.

Books and Other Publications

Presentations

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