OHNO Mutsuhito

J-GLOBAL         Last updated: Jun 14, 2019 at 10:46
 
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Name
OHNO Mutsuhito
Affiliation
Kyoto University
Section
Institute for Virus Research, Department of Genetics and Molecular,Biolgy Laboratory of Biochemistry
Job title
Professor
Degree
Doctor of Science

Academic & Professional Experience

 
1988
   
 
: JSPS Researcher, JSPS
 
1990
   
 
: Postdoctoral Fellow, The Rockfeller University
 
1991
   
 
: Postdoctoral Fellow, Case Western Reserve University
 
1992
   
 
: Research Associate, Faculty of Science,
 
 
   
 
University of Kyoto
 

Education

 
 
   
 
Kyoto University, Graduate School of Science
 
 
   
 
Faculty of Science, Kyoto University
 

Awards & Honors

 
 
The To-nen prize for promotion of molecular Biology Research,
 
 
1988
 

Published Papers

 
Translational control of Sox9 RNA by mTORC1 contributes to skeletogenesis.
Takashi Iezaki, Tetsuhiro Horie, Kazuya Fukasawa, Makoto Kitabatake, Yuka Nakamura, Gyujin Park, Yuki Onishi, Kakeru Ozaki, Takashi Kanayama, Manami Hiraiwa, Yuka Kitaguchi, Katsuyuki, Kaneda, Takayuki Manabe, Yasuhito Ishigaki, Mutsuhito Ohno and Eiichi Hinoi
Stem Cell Reports   11(1) 228-241   Jul 2018   [Refereed]
Ribosomal protein uS7/Rps5 serine-223 in protein kinase-mediated phosphorylation and ribosomal small subunit maturation.
Tomioka M, Shimobayashi M, Kitabatake M, Ohno M, Kozutsumi Y, Oka S, Takematsu H.
Sci Rep.   8(1) 1244   Jan 2018   [Refereed]
Wang DO, Ninomiya K, Mori C, Koyama A, Haan M, Kitabatake M, Hagiwara M, Chida K, Takahashi SI, Ohno M, Kataoka N.
Front Mol Biosci.   2017(Dec 22) 4-93   Dec 2017   [Refereed]
Ninomiya K, Ohno M, Kataoka N.
Genes Cells.   21(11) 1263-1269   Nov 2016   [Refereed]
Takeiwa T, Taniguchi I, Ohno M.
Genes Cells   20(4) 281-291   Apr 2015   [Refereed]
Masaki S, Yoshimoto R, Kaida D, Hata A, Satoh T, Ohno M, Kataoka N.
Int. J. Mol. Sci.   16(2) 3705-3721   Feb 2015   [Refereed]
Sakata T, Fujii K, Ohno M, Kitabatake M.
Biochem. Biophys. Res. Commun.   457(1) 90-94   Jan 2015   [Refereed]
Taniguchi I, Mabuchi N, Ohno M.
Nucleic Acids Res.   42(10) 6645-6658   Jun 2014   [Refereed]
Taniguchi, I., McCloskey, A. and Ohno, M.
Methods Cell Biol   122 395-413   May 2014   [Invited]
Izumi, H., McCloskey, A., Shinmyozu, K., Ohno, M.
Nucleic Acids Res.   42(6) 3998-4007   Apr 2014   [Refereed]
R. Yoshimoto; K. Okawa; M. Yoshida; M. Ohno; N. Kataoka
Genes to Cells   19(1) 78-87   2014   [Refereed]
Random mutagenesis of yeast 25S rRNA identify bases critical for 60S subunit structural integrity and function.
Nemoto N, Udagawa T, Chowdhury W, Kitabatake M, Shin B-s, Hiraishi H, Wang S, Singh CR, Brown SJ, Ohno M, Asano K.
Translation   1(2) e26402   2013   [Refereed]
N. Kataoka; I. Dobashi; M. Hagiwara; M. Ohno
Scientific Reports   3    2013   [Refereed]
A. McCloskey; I. Taniguchi; K. Shinmyozu; M. Ohno
Science   335(6076) 1643-1646   Mar 2012   [Refereed]
M. Ohno
RNA Biology   9(12) 1413-1417   2012   [Refereed]
N. Sasaki-Haraguchi; M.K. Shimada; I. Taniguchi; M. Ohno; A. Mayeda
Biochemical and Biophysical Research Communications   423(2) 289-294   2012   [Refereed]
K. Fujii; M. Kitabatake; T. Sakata; M. Ohno
EMBO Journal   31(11) 2579-2589   2012   [Refereed]
N. Kataoka; M.D. Diem; M. Yoshida; C. Hatai; I. Dobashi; G. Dreyfuss; M. Hagiwara; M. Ohno
Scientific Reports   1    2011   [Refereed]
R. Takemura; T. Takeiwa; I. Taniguchi; A. McCloskey; M. Ohno
Genes to Cells   16(10) 1035-1049   2011   [Refereed]
T. Suzuki; H. Izumi; M. Ohno
Journal of Cell Biology   190(4) 603-612   Aug 2010   [Refereed]
N. Kataoka; M. Fujita; M. Ohno
Molecular and Cellular Biology   29(12) 3243-3254   Jun 2009   [Refereed]
K. Fujii; M. Kitabatake; T. Sakata; A. Miyata; M. Ohno
Genes and Development   23(8) 963-974   Apr 2009   [Refereed]
K. Fukumura; I. Taniguchi; H. Sakamoto; M. Ohno; K. Inoue
Nucleic Acids Research   37(6) 1907-1914   Apr 2009   [Refereed]
[Control of RNA distribution between the nucleus and cytoplasm].
M. Ohno
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   54(16 Suppl) 2114-2120   2009   [Refereed]
[Quality control of ribosomal RNAs].
M. Kitabatake; K. Fujii; M. Ohno
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   54(16 Suppl) 2195-2200   2009   [Refereed]
[Intron turnover in eukaryotes].
N. Kataoka; R. Yoshimoto; M. Fujita; M. Ohno
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   54(16 Suppl) 2060-2065   2009   [Refereed]
H. Fuke; M. Ohno
Nucleic Acids Research   36(3) 1037-1049   Feb 2008   [Refereed]
I. Taniguchi; M. Ohno
Molecular and Cellular Biology   28(2) 601-608   Jan 2008   [Refereed]
S. Kitao; A. Segref; J. Kast; M. Wilm; I.W. Mattaj; M. Ohno
Molecular and Cellular Biology   28(1) 487-497   Jan 2008   [Refereed]
N. Mabuchi; K. Masuyama; M. Ohno
Methods in Molecular Biology   488 257-265   2008
K. Masuyama; I. Taniguchi; K. Okawa; M. Ohno
Biochemical and Biophysical Research Communications   359(3) 580-585   2007   [Refereed]
I. Kashima; A. Yamashita; N. Izumi; N. Kataoka; R. Morishita; S. Hoshino; M. Ohno; G. Dreyfuss; S. Ohno
Genes and Development   20(3) 355-367   Feb 2006   [Refereed]
M. Dasso; M. Ohno; J. Pines; M. Stewart
Traffic   7(4) 474-478   2006   [Refereed]
J. Okuda; T. Toyotome; N. Kataoka; M. Ohno; H. Abe; Y. Shimura; A. Seyedarabi; R. Pickersgill; C. Sasakawa
Biochemical and Biophysical Research Communications   333(2) 531-539   2005   [Refereed]
D. Nameki; E. Kodama; M. Ikeuchi; N. Mabuchi; A. Otaka; H. Tamamura; M. Ohno; N. Fujii; M. Matsuoka
Journal of Virology   79(2) 764-770   2005   [Refereed]
K. Masuyama; I. Taniguchi; N. Kataoka; M. Ohno
Genes to Cells   9(10) 959-965   2004   [Refereed]
K. Masuyama; I. Taniguchi; N. Kataoka; M. Ohno
Genes and Development   18(17) 2074-2085   2004   [Refereed]
Exportin-mediated nuclear export of proteins and ribonucleoproteins.
M. Fornerod; M. Ohno
Results and problems in cell differentiation   35 67-91   2002   [Refereed]
M. Ohno; A. Segref; S. Kuersten; I.W. Mattaj
Molecular Cell   9(3) 659-671   2002   [Refereed]
S. Kuersten; M. Ohno; I.W. Mattaj
Trends in Cell Biology   11(12) 497-503   2001   [Refereed]
C. Mazza; M. Ohno; A. Segref; I.W. Mattaj; S. Cusack
Molecular Cell   8(2) 383-396   2001   [Refereed]
M. Ohno; A. Segref; A. Bachi; M. Wilm; I.W. Mattaj
Cell   101(2) 187-198   2000   [Refereed]
RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase
P. Askjaer; A. Bachi; M. Wilm; F.R. Bischoff; D.L. Weeks; V. Ogniewski; M. Ohno; C. Niehrs; J. Kjems; I.W. Mattaj; M. Fornerod
Molecular and Cellular Biology   19(9) 6276-6285   1999   [Refereed]
M. Ohno; I.W. Mattaj
Current Biology   9(2) R66-R69   1999   [Refereed]
K.F. Wilson; P. Fortes; U.S. Singh; M. Ohno; I.W. Mattaj; R.A. Cerione
Journal of Biological Chemistry   274(7) 4166-4173   1999   [Refereed]
Importins and exportins: receptors involved in nucleocytoplasmic transport of proteins and RNAs
M. Ohno
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   43(9) 1255-1264   1998   [Refereed]
M. Ohno; M. Fornerod; I.W. Mattaj
Cell   92(3) 327-336   1998   [Refereed]
N. Nikoh; N. Iwabe; K.-I. Kuma; M. Ohno; T. Sugiyama; Y. Watanabe; K. Yasui; Z. Shi-Cui; K. Hori; Y. Shimura; T. Miyata
Journal of Molecular Evolution   45(1) 97-106   Jul 1997   [Refereed]
M. Fornerod; M. Ohno; M. Yoshida; I.W. Mattaj
Cell   90(6) 1051-1060   1997   [Refereed]

Misc

 
Identification of RNA helicase used in U snRNA export
Ichiro Taniguchi, Mutsuhito Ohno
   Jul 2017
Systematic analysis of hnRNP C domains in sorting RNA polymerase II transcripts
Sayaka Dantsuji, Ichiro Taniguchi, Mutsuhito Ohno
   Jul 2017
Systematic analysis of hnRNP C domains in sorting RNA polymerase II transcripts
Sayaka Dantsuji, Ichiro Taniguchi, Mutsuhito Ohno
15th International Student Seminar      Feb 2017
A bridge that links an E3 ubiquitin ligase complex and nonfunctional 60S ribosomal particles.
Kitabatake, M., Sakata, T. and Ohno, M.
18th RNA meeting. Kyoto.      Jun 2016
Exportin-5 mediates nuclear export of SRP RNA in vertebrates.
Takeiwa,T,and Ohno, M.
18th RNA meeting. Kyoto      Jun 2016
Selective ubiquitination and degradation of defective 60S particles
Kitabatake, M., Sakata, T. and Ohno, M.
RNA2016 satellite-symposium, Kyoto      Jun 2016   [Invited]
Quality Control of Eukaryotic Ribosomes
Kitabatake M., Sakata T., Ohno M.
The 18th Tokyo RNA Club - Ribosome and Translational Apparatus      Jan 2016   [Invited]
HIV-1 Rev protein specifies the viral RNA export pathway by suppressing TAP/NXF1 recruitment
Taniguchi, I. and Ohno, M.
East Asia Joint Symposium      Nov 2015   [Invited]
A cellular mechanism that sorts RNA transcripts according to their lengths
OHNO Mutsuhito
The 10th International Symposium for the Inter-institutional Network (ISIIN)      Jul 2015   [Invited]
RNAi-mediated depletion of hnRNP C revealed a novel surveillance mechanism of proper mRNP formation.
Ohno M, McCloskey A
RNA Sciences in Cell and Developmental Biology. kobe.Dec.7.2013      Dec 2013
HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export.
Ohno M, McCloskey A, Taniguchi I
第86回 日本生化学学会. 横浜市. 2013年9月11-13日      Sep 2013
Classical low-throughput analyses on RNA export from the nucleus.
OHNO Mutsuhito
The2th RNA and Biofunctions-ASIA Study.hukuoka.Jan 10.2013.      Jan 2013
HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export.
McCloskey, A. Taniguchi,I,. Shinmyozu,K, and Ohno,M
The 10th International Student Seminar, Kyoto Japan.Mar 5-8.2012      May 2012
Characterization of a degradation intermediate of the nonfunctional ribosome.
Sakai T., Fujii K., Kitabatake M., Ohno M.
第34 回日本分子生物学会年会, 横浜市, 2011年12月13-16日      2011   [Refereed]
Nonfunctional rRNA decay functionally requires proteasome activity.
Fujii K., Kitabatake M., Sakata T., Sakai T., Ohno M.
第34 回日本分子生物学会年会, 横浜市, 2011年12月13-16日      2011   [Refereed]
A novel activity of HIV-1 Rev protein to remodel export RNPs in directing virus-specific RNA export.
Taniguchi I., Mabuchi N., Ohno M.
第34 回日本分子生物学会年会, 横浜市, 2011年12月13-16日      2011   [Refereed]
Selective Degradation of nonfunctional ribosomal particles.
北畠真, 藤井耕太郎, 酒井朗恵, 大野睦人
第12 回日本RNA 学会年会, 東京,2010年7 月27-29 日      2010   [Refereed]
Cis-acting RNA elements and trans-acting factors for nuclear pre-mRNA retention
Takeiwa T, Taniguchi I, Ohno M
The 17th East Asia Joint Symposium. Jun 30 - Jul 3      2010   [Refereed]
Functional Decay of Nonfunctional 25 S rRNA Requires Proteasome Activity.
Fujii K., Sakata T., Kitabatake M., Miyata A. and Ohno M
The 16th East Asia Joint Conference on Biomedical Research. Kyoto, Japan. Sep 13-14, 2009 ・      2009   [Refereed]
Quality Control of Ribosomal RNAs in S.cerevisiae
Fujii K., Kitabatake M., Sakata T., Ohno M.
The 6th International Student Seminar International Symposium Kyoto, Japan March 6, 2008.      2008   [Refereed]
I. Taniguchi; K. Masuyama; M. Ohno
Proceedings of the National Academy of Sciences of the United States of America   104(34) 13684-13689   2007   [Refereed]
RNA length defines RNA export pathway.
Masuyama K., Taniguchi I., Ohno M.
Shirokane International Symposium, Tokyo, Japan, July 22-23, 2005      2005   [Refereed]
Identity elements in mRNA export
大野睦人
国際シンポジウム「細胞核機能の分子スイッチRanと細胞周期」兵庫、2005年10月2 日      2005   [Refereed]
M. Ohno; H. Sakamoto; Y. Shimura
Proceedings of the National Academy of Sciences of the United States of America   84(15) 5187-5191   1987   [Refereed]

Conference Activities & Talks

 
A cellular mechanism that sorts RNA transcripts according to their lengths. [Invited]
OHNO Mutsuhito
The 10th International Symposium for the Inter-institutional Network (ISIIN)   23 Jul 2015   
RNAi-mediated depletion of hnRNP C revealed a novel surveillance mechanism of proper mRNP formation.
OHNO Mutsuhito
RNA Sciences in Cell and Developmental Biology.   7 Dec 2013   
Inhibition of mRNA export through dispersion of nucleoporins. [Invited]
OHNO Mutsuhito
3 Dec 2013   
HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export. [Invited]
OHNO Mutsuhito
11 Sep 2013   
Classical low-throughput analyses on RNA export from the nucleus [Invited]
OHNO Mutsuhito
The2th RNA and Biofunctions-ASIA Study   10 Jan 2013   

Research Grants & Projects

 
Nucleocytoplasmic Transport of macromolecules
RNA Processing