MURAKAMI Makoto

J-GLOBAL         Last updated: Oct 11, 2018 at 14:28
 
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Name
MURAKAMI Makoto
E-mail
makmurakm.u-tokyo.ac.jp
Affiliation
The University of Tokyo
Section
Graduate School of Medicine
Job title
Project leader
Degree
PhD(The University of Tokyo)

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
Apr 2017
 - 
Today
Professor, Graduate School of Medicine, The University of Tokyo
 
Apr 2011
 - 
Mar 2017
Project Leader, Lipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science
 
Apr 2005
 - 
Mar 2011
Project Leader, Biomembrane Signaling Project, Tokyo Metropolitan Institute of Medical Science
 

Education

 
 
 - 
1991
Department of Health Chemistry, Graduate School, Division of Food and Medical Sciences, The University of Tokyo
 
 
 - 
1986
Faculty of Pharmaceutical Science, The University of Tokyo
 

Awards & Honors

 
2000
Young Investigators Award, The Japanese Society of Inflammation and Regeneration
 
1999
Young Investigators Award, The Pharmaceutical Society of Japan
 

Published Papers

 
Li X, Park SJ, Jin F, Deng Y, Yang JH, Chang JH, Kim DY, Kim JA, Lee YJ, Murakami M, Son KH, Chang HW
Biochemical pharmacology   152 362-372   Jun 2018   [Refereed]
Hirabayashi T, Murakami M, Kihara A
Biochimica et biophysica acta. Molecular and cell biology of lipids      Oct 2018   [Refereed]
Shimanaka Y, Kono N, Taketomi Y, Arita M, Okayama Y, Tanaka Y, Nishito Y, Mochizuki T, Kusuhara H, Adibekian A, Cravatt BF, Murakami M, Arai H
Nature medicine   23(11) 1287-1297   Nov 2017   [Refereed]
Murase R, Taketomi Y, Miki Y, Nishito Y, Saito M, Fukami K, Yamamoto K, Murakami M
Scientific reports   7(1) 12261   Sep 2017   [Refereed]
Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T
Journal of clinical biochemistry and nutrition   62(2) 139-147   Mar 2018   [Refereed]
Aikawa S, Kano K, Inoue A, Wang J, Saigusa D, Nagamatsu T, Hirota Y, Fujii T, Tsuchiya S, Taketomi Y, Sugimoto Y, Murakami M, Arita M, Kurano M, Ikeda H, Yatomi Y, Chun J, Aoki J
The EMBO journal   36(14) 2146-2160   Jul 2017   [Refereed]
Li X, Lee YJ, Jin F, Park YN, Deng Y, Kang Y, Yang JH, Chang JH, Kim DY, Kim JA, Chang YC, Ko HJ, Kim CH, Murakami M, Chang HW
Scientific reports   7(1) 6444   Jul 2017   [Refereed]
Irie A, Yamamoto K, Miki Y, Murakami M
Scientific reports   7 46715   Apr 2017   [Refereed]
Hirabayashi T, Anjo T, Kaneko A, Senoo Y, Shibata A, Takama H, Yokoyama K, Nishito Y, Ono T, Taya C, Muramatsu K, Fukami K, Muñoz-Garcia A, Brash AR, Ikeda K, Arita M, Akiyama M, Murakami M
Nature communications   8 14609   Mar 2017   [Refereed]
Murakami M, Nakatani Y, Atsumi GI, Inoue K, Kudo I
Critical reviews in immunology   37(2-6) 121-179   2017   [Refereed]
Taketomi Y, Murakami M
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan   137(5) 503-515   2017   [Refereed]
Murakami M
Proceedings of the Japan Academy. Series B, Physical and biological sciences   93(9) 677-702   2017   [Refereed]
Hata S, Kitamura F, Yamaguchi M, Shitara H, Murakami M, Sorimachi H
The Journal of biological chemistry   291(53) 27313-27322   Dec 2016   [Refereed]
Tanigawa H, Miyata K, Tian Z, Aoi J, Kadomatsu T, Fukushima S, Ogata A, Takeda N, Zhao J, Zhu S, Terada K, Endo M, Morinaga J, Sugizaki T, Sato M, Morioka MS, Manabe I, Mashimo Y, Hata A, Taketomi Y, Yamamoto K, Murakami M, Araki K, Jinnin M, Ihn H, Oike Y
Scientific reports   6 34690   Oct 2016   [Refereed]
Shigematsu M, Koga T, Ishimori A, Saeki K, Ishii Y, Taketomi Y, Ohba M, Jo-Watanabe A, Okuno T, Harada N, Harayama T, Shindou H, Li JD, Murakami M, Hoka S, Yokomizo T
Scientific reports   6 34560   Oct 2016   [Refereed]
Peña L, Meana C, Astudillo AM, Lordén G, Valdearcos M, Sato H, Murakami M, Balsinde J, Balboa MA
Biochimica et biophysica acta   1861(9 Pt A) 1083-1095   Sep 2016   [Refereed]
Miki Y, Kidoguchi Y, Sato M, Taketomi Y, Taya C, Muramatsu K, Gelb MH, Yamamoto K, Murakami M
The Journal of biological chemistry   291(30) 15588-15601   Jul 2016   [Refereed]
Yamamoto K, Miki Y, Sato H, Nishito Y, Gelb MH, Taketomi Y, Murakami M
The Journal of biological chemistry   291(30) 15602-15613   Jul 2016   [Refereed]
Murase R, Sato H, Yamamoto K, Ushida A, Nishito Y, Ikeda K, Kobayashi T, Yamamoto T, Taketomi Y, Murakami M
The Journal of biological chemistry   291(13) 6895-6911   Mar 2016   [Refereed]
Sato H, Taketomi Y, Murakami M
Inflammation and regeneration   36 7   2016   [Refereed]

Misc

 
Secreted phospholipase A2 specificity on natural membrane phospholipids
MURAKAMI Makoto
Methods Enzymol   583 101-117   2017   [Refereed][Invited]
The roles of the secreted phospholipase A2 (sPLA2) gene family in immunology
MURAKAMI Makoto
Adv. Immunol   132 91-134   2016   [Refereed][Invited]
食品と開発
MURAKAMI Makoto
50(2) 9-11   2015
Phospholipase A2 and lipid mediators in health and disease
MURAKAMI Makoto
Bioactive Lipid Mediators: Current Reviews and Protocols   23-42   2015   [Invited]
Phospholipase A2
MURAKAMI Makoto
Encyclo. Sig. Mol.   1401-1409   2012   [Invited]
Unraveling the secrets of secreted phospholipase A2
MURAKAMI Makoto
Trends Cell. Mol. Biol.   7 57-71   2012   [Refereed][Invited]
Phospholipase A2 as a potential target of airway diseases
MURAKAMI Makoto
Obstructive Airway Diseases: Role of Lipid Mediators   39-67   2011   [Refereed][Invited]
Hara, S., Kamei, D., Sasaki, Y., Tanemoto, A., Nakatani, Y., and Murakami, M.
Biochimie   92(6) 651-659   2010
Murakami, M., Taketomi, Y., Girard, G., Yamamoto, K., and Lambeau, G.
Biochimie   92(6) 561-582   2010
Escoffier, J., Jemel, I., Tanemoto, A., Taketomi, Y., Payre, C., Coatrieux, C., Sato, H., Yamamoto, K., Masuda, S., Pernet-Gallay, K., Pierre, V., Hara, S., Murakami, M., De Waard, M., Lambeau, G., and Arnoult, C.
Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice.
J. Clin. Invest.   120 1415-1428   2010
Sato, H., Taketomi, T., Isogai, Y., Miki, Y., Yamamoto, K., Masuda, S., Hosono, T., Arata, S., Ishikawa, Y., Ishii, T., Kobayashi, T., Nakanishi, H., Ikeda, K., Taguchi, R., Hara, S., Kudo, I., and Murakami, M.
J. Clin. Invest.   120(5) 1400-1414   2010
Ishikawa, Y, Kimura-Matsumoto, M, Murakami, M, Yamamoto, K, Akasaka, Y, and Ishii, T.
J. Ather. Thrombosis.   16(6) 829-839   2010
Kamei, D., Murakami, M., Sasaki, Y., Nakatani, Y., Majima, M., Ishikawa, Y., Ishii, T., Uematsu, S., Akira, S., Hara, S., and Kudo, I.
Biochem. J.   425(2) 361-371   2009
Sato, H., Taketomi, Y., Isogai, Y., Masuda, S., Kobayashi, T., Yamamoto, K., and Murakami, M.
Biochem. J.   421(1) 17-27   2009
Nakamura, Y., Kambe, N., Saito, M., Nishikomiri, R., Kim, Y-G., Murakami, M., Núñez, G., and Matsue, H.
J. Exp. Med.   206 1037-1046   2009
Maehama, T., Tanaka, M., Nishina, H., Murakami, M., Kanaho, Y., and Hanada, K.
J. Biol. Chem.   283(50) 35053-35059   2008
Sato, H., Kato, R., Isogai, Y., Saka, G., Ohtsuki, M., Taketomi, Y., Yamamoto, K., Tsutsumi, K., Yamada, J., Masuda, S., Ishikawa, Y., Ishii, T., Kobayashi, T., Ikeda, K., Taguchi, R., Hatakeyama, S., Hara, S., Kudo, I., Itabe, H., and Murakami, M.
J. Biol. Chem.   283(48) 33483-33497   2008
Ueno, N., Taketomi, Y., Koga, K., Atsumi, Y., Kikuchi-Yanoshita, R., Kudo, I., and Murakami, M.
Biochim. Biophys. Acta.   1781 415-421   2008
Yamakawa, K., Kamekura, S., Kawamura, N., Saegusa, M., Kamei, D., Murakami, M., Kudo, I., Uematsu, S., Akira, S., Chung, U.I., Nakamura, K., and Kawaguchi, H.
Arthritis Rheum.   58 172-183   2008
Takano, H., Nakazawa, S., Okuno, Y., Shirata, N., Tsuchiya, S., Kainoh, T., Takamatsu, S., Furuta, K., Taketomi, Y., Naito, Y., Takematsu, H., Kozutsumi, Y., Tsujimoto, G., Murakami, M., Kudo, I., Ichikawa, A., Nakayama, K., Sugimoto, Y., Tanaka, S.
FEBS Lett.   582(10) 1444-1450   2008
Masuda, S., Yamamoto, K., Hirabayashi, T., Ishikawa, Y., Ishii, T., Kudo, I., and Murakami, M.
Biochem. J.   409(2) 429-438   2008
Kimura-Matsumoto, M., Ishikawa, Y., Komiyama, K., Tsuruta, T., Murakami, M., Masuda, S., Akasaka, Y., Ito, K., Ishiguro, S., Morita, H., Sato, S., and Ishii, T.
Atherosclerosis   196 81-91   2008
Moon, T.C., Quan, Z., Kim, J., Kim, H.P., Kudo, I., Murakami, M., Park, H., and Chang, H.W.
Bioorg. Med. Chem.   15 7138-7143   2007
Kuwata, H., Fujimoto, C., Yoda, E., Nakatani, Y., Hara, S., Murakami, M., and Kudo, I.
J. Biol. Chem.   282(28) 20124-20132   2007
Taketomi, Y., Sunaga, K., Tanaka, S., Nakamura, M., Arata, S., Okuda, T., Moon, T. C., Chang, H. W., Sugimoto, Y., Kokame, K., Miyata, T., Murakami, M., and Kudo, I.
J. Immunol.   178 7042-7053   2007
Ohtsuki, M., Taketomi, Y., Arata, S., Masuda, S., Ishikawa, Y., Ishii, T., Takanezawa, Y., Aoki, J., Arai, H., Yamamoto, K., Kudo, I., and Murakami. M.
J. Biol. Chem.   281(47) 36420-36433   2006

Books etc

 
Bioactive Lipid Mediators: Current Reviews and Protocols
MURAKAMI Makoto (Part:Supervisor)
Springer   2015   
PLA2 and lipid mediators
Biochimie   2010   

Conference Activities & Talks

 
Phospholipid metabolism in healthy and maladaptive aging [Invited]
MURAKAMI Makoto
The 2nd Stockholm-Tokyo Workshop   29 Oct 2018   
Long-lasting sPLA2 research with Mike Gelb [Invited]
MURAKAMI Makoto
Gelb Research Symposium   20 Jul 2018   
Lipoquality control by the phospholipase A2 family in the skin [Invited]
MURAKAMI Makoto
Tokyo 2018 Cell and Developmental Biology Meeting   8 Jun 2018   
Updating the PLA2 knockout studies: immunity, metabolic diseases, and beyond [Invited]
MURAKAMI Makoto
Bioactive Lipids Conference 2018   29 Mar 2018   
Lipoquality control by the phospholipase A2 family in the skin [Invited]
MURAKAMI Makoto
The 15th International Conference on Bioactive Lipids in Inflammation, Cancer and Related Diseases   24 Oct 2017   

Research Grants & Projects

 
Regulatory mechanisms of allergic diseases by lipids
AMED: Practical Research Project for Allergic Diseases and Immunology
Project Year: Apr 2018 - Mar 2021    Investigator(s): MURAKAMI Makoto
Novel insights into lipids toward metabolic health
JSPS: Grant-in-Aid for Scientific Research (A)
Project Year: Apr 2016 - Mar 2021    Investigator(s): MURAKAMI Makoto
Regulation of inflammation cellular society by lipids toward better understanding of allergic diseases
JSPS: Grant-in-Aid for Scientific Research on Innovative Areas
Project Year: Apr 2018 - Mar 2019    Investigator(s): MURAKAMI Makoto
Exploration of disease-associated lipid maps by PLA2 metabolome and its clinical application
AMED: CREST
Project Year: Oct 2013 - Mar 2019    Investigator(s): MURAKAMI Makoto
Phospholipid Recycling
JSPS: Grant-in-Aid for challenging Exploratory Research
Project Year: Apr 2014 - Mar 2016    Investigator(s): MURAKAMI Makoto
Novel lipid networks regulated by the phospholipase A2 family
MEXT: Grant-in-Aid for Scientific Research on Innovative Areas
Project Year: Oct 2010 - Mar 2015    Investigator(s): MURAKAMI Makoto
Metabolism of endogenous GPC and its application
JSPS: Grant-in-Aid for challenging Exploratory Research
Project Year: Apr 2012 - Mar 2014    Investigator(s): MURAKAMI Makoto
Functional deorphaning of novel phospholipase
LSPS: Grant-in-Aid for Scientific Research (B)
Project Year: Apr 2011 - Mar 2014    Investigator(s): MURAKAMI Makoto
Analysis of the functions of sPLA2 family
JSPS: Grant-in-Aid for Scientific Research (B)
Project Year: Apr 2008 - Mar 2011    Investigator(s): MURAKAMI Makoto
Biological functions of phospholipase A2 enzymes
JST Basic Research Programs (Precursory Research for Embryonic Science and Technology :PRESTO)
Project Year: 2005 - 2008
Analysis of the functions of PGE2 synthase as a novel drug target
JSPS: Grant-in-Aid for Scientific Research (B)
Project Year: Apr 2005 - Mar 2007    Investigator(s): MURAKAMI Makoto
Analysis of PGE2 synthase as a novel drug target
JSPS: Grant-in-Aid for Scientific Research (B)
Project Year: Apr 2003 - Mar 2005    Investigator(s): MURAKAMI Makoto
Arachidonate metabolism in mast cell differentiation
MEXT: Grant-in-Aid for Scientific Research on Priority Areas
Project Year: Oct 2000 - Mar 2004    Investigator(s): MURAKAMI Makoto
Swich on/off of arachidonic acid metabolism
JSPS: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2001 - Mar 2003    Investigator(s): MURAKAMI Makoto
IgE-independent activation of mast cells
JSPS: Grant-in-Aid for Scientific Research (B)
Project Year: Apr 1998 - Mar 2001    Investigator(s): MURAKAMI Makoto
Coupling of lipid mediator-biosynthetic enzymes in mast cells
JSPS: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 1996 - Mar 1998    Investigator(s): MURAKAMI Makoto